Isolation of live label-retaining cells and cells undergoing asymmetric cell division via nonrandom chromosomal cosegregation from human cancers

Stem Cells and Development

Volumn 20, Issue 10, 2011, Pages 1649-1658

  Hari, Danielle ^a,b   Xin, Hong Wu ^a   Jaiswal, Kshama ^a   Wiegand, Gordon ^a   Kim, Bo Kyu ^a   Ambe, Che ^a   Burka, Douglas ^a   Koizumi, Tomotake ^a   Ray, Satyajit ^a   Garfield, Susan ^a   Thorgeirsson, Snorri ^a   Avital, Itzhak ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CANCER STEM CELL; CELL DIVISION; CELL ISOLATION; CHROMOSOME ANALYSIS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; LABEL RETAINING CELL; PRIMED IN SITU LABELING; PRIORITY JOURNAL;

ASYMMETRIC CELL DIVISION; CELL SEPARATION; CELL SURVIVAL; CHROMOSOME SEGREGATION; COLOR; HUMANS; MICROSCOPY, CONFOCAL; MICROSCOPY, FLUORESCENCE; NEOPLASMS; NUCLEOTIDES; STAINING AND LABELING;

EID: 80053410661     PISSN: 15473287     EISSN: 15578534     Source Type: Journal    
DOI: 10.1089/scd.2010.0455     Document Type: Article

References (32)

1. Morrison SJ and J Kimble. (2006). Asymmetric and symmetric stem-cell divisions in development and cancer. Nature 441:1068-1074. (Pubitemid 43990718)
2. McCulloch EA and JE Till. (2005). Perspectives on the properties of stem cells. Nat Med 11:1026-1028. (Pubitemid 41486814)
3. Strain AJ, HA Crosby, S Nijjar, DA Kelly and SG Hubscher. (2003). Human liver-derived stem cells. Semin Liver Dis 23:373-384.
4. Visvader JE and GJ Lindeman. (2008). Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 8:755-768.
5. Goodell MA, K Brose, G Paradis, AS Conner and RC Mulligan. (1996). Isolation and functional properties of murine hematopoietic stem cells that are replicating in vivo. J Exp Med 183:1797-1806. (Pubitemid 26134320)
6. Potten CS. (1971). Early and late incorporation of tritiated thymidine into skin cells and the presence of a long-lived G 0-specific precursor pool. J Cell Biol 51:855-861.
7. Bickenbach JR. (1981). Identification and behavior of labelretaining cells in oral mucosa and skin. J Dent Res 60 Spec No C:1611-1620.
8. Morris RJ and CS Potten. (1994). Slowly cycling (labelretaining) epidermal cells behave like clonogenic stem cells in vitro. Cell Prolif 27:279-289. (Pubitemid 24148610)
9. Zhang HB, CP Ren, XY Yang, L Wang, H Li, M Zhao, H Yang and KT Yao. (2007). Identification of label-retaining cells in nasopharyngeal epithelia and nasopharyngeal carcinoma tissues. Histochem Cell Biol 127:347-354.
10. Potten CS, R Gandara, YR Mahida, M Loeffler and NA Wright. (2009). The stem cells of small intestinal crypts: where are they? Cell Prolif 42:731-750.
11. Li F, L Lu and J Lu. Identification and location of label retaining cells in mouse liver. J Gastroenterol 45:113-121.
12. Oliver JA, A Klinakis, FH Cheema, J Friedlander, RV Sampogna, TP Martens, C Liu, A Efstratiadis and Q Al-Awqati. (2009). Proliferation and migration of label-retaining cells of the kidney papilla. J Am Soc Nephrol 20:2315-2327.
13. Cairns J. (1975). Mutation selection and the natural history of cancer. Nature 255:197-200.
14. Lark KG, RAConsigli and HCMinocha. (1966). Segregation of sister chromatids in mammalian cells. Science 154:1202-1205.
15. Potten CS, WJ Hume, P Reid and J Cairns. (1978). The segregation of DNA in epithelial stem cells. Cell 15:899-906.
16. Potten CS, G Owen and D Booth. (2002). Intestinal stem cells protect their genome by selective segregation of template DNA strands. J Cell Sci 115:2381-2388. (Pubitemid 34752981)
17. Booth BW, CA Boulanger and GH Smith. (2008). Selective segregation of DNA strands persists in long-label-retaining mammary cells during pregnancy. Breast Cancer Res 10:R90.
18. Merok JR, JA Lansita, JR Tunstead and JL Sherley. (2002). Cosegregation of chromosomes containing immortal DNA strands in cells that cycle with asymmetric stem cell kinetic . Cancer Res 62:6791-6795. (Pubitemid 35424060)
19. Karpowicz P, C Morshead, A Kam, E Jervis, J Ramunas, V Cheng and D van der Kooy. (2005). Support for the immortal strand hypothesis: neural stem cells partition DNA asymmetrically in vitro. J Cell Biol 170:721-732. (Pubitemid 41242105)
20. Rambhatla L, S Ram-Mohan, JJ Cheng and JL Sherley. (2005). Immortal DNA strand cosegregation requires p53/ IMPDH-dependent asymmetric self-renewal associated with adult stem cells. Cancer Res 65:3155-3161. (Pubitemid 40524596)
21. Shinin V, B Gayraud-Morel,D Gomes and S Tajbakhsh. (2006). Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells. Nat Cell Biol 8:677-687.
22. Cairns J. (2006). Cancer and the immortal strand hypothesis. Genetics 174:1069-1072. (Pubitemid 44808282)
23. Rando TA. (2006). Stem cells, ageing and the quest for immortality. Nature 441:1080-1086. (Pubitemid 43990720)
24. Rando TA. (2007). The immortal strand hypothesis: segregation and reconstruction. Cell 129:1239-1243. (Pubitemid 46962100)
25. Conboy MJ, AO Karasov and TA Rando. (2007). High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny. PLoS Biol 5:e102.
26. Pine SR, BM Ryan, L Varticovski, AI Robles and CC Harris. Microenvironmental modulation of asymmetric cell division in human lung cancer cells. Proc Natl Acad Sci U S A 107:2195-2200.
27. Lansdorp PM. (2007). Immortal strands? Give me a break. Cell 129:1244-1247.
28. Kiel MJ, S He, R Ashkenazi, SN Gentry, M Teta, JA Kushner, TL Jackson and SJ Morrison. (2007). Haematopoietic stem cells do not asymmetrically segregate chromosomes or retain BrdU. Nature 449:238-242. (Pubitemid 47402371)
29. Morris RJ and CS Potten. (1999). Highly persistent labelretaining cells in the hair follicles of mice and their fate following induction of anagen. J Invest Dermatol 112:470-475. (Pubitemid 29171937)
30. Potten CS. (2004). Keratinocyte stem cells, label-retaining cells and possible genome protection mechanisms. J Investig Dermatol Symp Proc 9:183-195. (Pubitemid 39108121)
31. Bussard KM, CA Boulanger, FS Kittrell, F Behbod, D Medina and GH Smith. Immortalized, premalignant epithelial cell populations contain long-lived, label-retaining cells that asymmetrically divide and retain their template DNA. Breast Cancer Res 12:R86.
32. Hart LS and WS El-Deiry. (2008). Invincible, but not invisible: imaging approaches toward in vivo detection of cancer stem cells. J Clin Oncol 26:2901-2910.