Selective segregation of DNA strands persists in long label retaining mammary cells during pregnancy

Breast Cancer Research

Volumn 10, Issue 5, 2008, Pages

  Booth, Brian W ^a   Boulanger, Corinne A ^a   Smith, Gilbert H ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; BIOLOGICAL MARKER; BROXURIDINE; CD31 ANTIGEN; DESMIN; DNA; ESTROGEN RECEPTOR ALPHA; KERATIN; PROGESTERONE RECEPTOR; TRITIUM;

ADULT STEM CELL; ANAPHASE; ANIMAL; ARTICLE; BIOLOGICAL MODEL; BREEDING; CELL LINEAGE; CHEMISTRY; CHROMATID; COMPARATIVE STUDY; CYTOLOGY; DNA TEMPLATE; FEMALE; GENETICS; METABOLISM; MOUSE; PREGNANCY; UDDER;

ACTINS; ADULT STEM CELLS; ANAPHASE; ANIMALS; ANTIGENS, CD31; BIOLOGICAL MARKERS; BROMODEOXYURIDINE; CELL LINEAGE; CHROMATIDS; DESMIN; DNA; ESTROGEN RECEPTOR ALPHA; FEMALE; KERATINS; MAMMARY GLANDS, ANIMAL; MICE; MODELS, GENETIC; PREGNANCY; PREGNANCY, ANIMAL; RECEPTORS, PROGESTERONE; TEMPLATES, GENETIC; TRITIUM;

EID: 59449097500     PISSN: 14655411     EISSN: 1465542X     Source Type: Journal    
DOI: 10.1186/bcr2188     Document Type: Article

References (36)

1. Cairns J. Mutation selection and the natural history of cancer. Nature 1975, 255:197-200. 10.1038/255197a0, 1143315.
2. Cairns J. Somatic stem cells and the kinetics of mutagenesis and carcinogenesis. Proc Natl Acad Sci USA 2002, 99:10567-10570. 124976, 12149477, 10.1073/pnas.162369899.
3. Potten CS, Hume WJ, Reid P, Cairns J. The segregation of DNA in epithelial stem cells. Cell 1978, 15:899-906. 10.1016/0092-8674(78)90274-X, 728994.
4. Potten CS, Owen G, Booth D. Intestinal stem cells protect their genome by selective segregation of template DNA strands. J Cell Sci 2002, 115:2381-2388.
5. Merok JR, Lansita JA, Tunstead JR, Sherley JL. Cosegregation of chromosomes containing immortal DNA strands in cells that cycle with asymmetric stem cell kinetics. Cancer Res 2002, 62:6791-6795.
6. Smith GH. Label-retaining epithelial cells in mouse mammary gland divide asymmetrically and retain their template DNA strands. Development 2005, 132:681-687. 10.1242/dev.01609, 15647322.
7. Shinin V, Gayraud-Morel B, Gomes D, Tajbakhsh S. Asymmetric division and cosegregation of template DNA strands in adult muscle satellite cells. Nat Cell Biol 2006, 8:677-687. 10.1038/ncb1425, 16799552.
8. Conboy MJ, Karasov AO, Rando TA. High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny. PLoS Biol 2007, 5:e102. 1852584, 17439301, 10.1371/journal.pbio.0050102.
9. Hennighausen L, Robinson GW. Information networks in the mammary gland. Nat Rev Mol Cell Biol 2005, 6:715-725. 10.1038/nrm1714, 16231422.
10. Traurig HH, Morgan CF. Autoradiographic studies of the epithelium of mammary gland as influenced by ovarian hormones. Proc Soc Exp Biol Med 1964, 115:1076-1080.
11. Bresciani F. Effect of ovarian hormones on duration of DNA synthesis in cells of the C3h mouse mammary gland. Exp Cell Res 1965, 38:13-32. 10.1016/0014-4827(65)90423-4, 14281193.
12. Zeps N, Dawkins HJ, Papadimitriou JM, Redmond SL, Walters MI. Detection of a population of long-lived cells in mammary epithelium of the mouse. Cell Tissue Res 1996, 286:525-536. 10.1007/s004410050722, 8929355.
13. Zeps N, Bentel JM, Papadimitriou JM, D'Antuono MF, Dawkins HJ. Estrogen receptor-negative epithelial cells in mouse mammary gland development and growth. Differentiation 1998, 62:221-226. 10.1046/j.1432-0436.1998.6250221.x, 9566307.
14. Zeps N, Bentel JM, Papadimitriou JM, Dawkins HJ. Murine progesterone receptor expression in proliferating mammary epithelial cells during normal pubertal development and adult estrous cycle. Association with eralpha and erbeta status. J Histochem Cytochem 1999, 47:1323-1330.
15. Chepko G, Smith GH. Three division-competent, structurally-distinct cell populations contribute to murine mammary epithelial renewal. Tissue Cell 1997, 29:239-253. 10.1016/S0040-8166(97)80024-9, 9149446.
16. Smith CA, Monaghan P, Neville AM. Basal clear cells of the normal human breast. Virchows Arch A Pathol Anat Histopathol 1984, 402:319-329. 10.1007/BF00695085, 6422622.
17. Pechoux C, Gudjonsson T, Ronnov-Jessen L, Bissell MJ, Petersen OW. Human mammary luminal epithelial cells contain progenitors to myoepithelial cells. Dev Biol 1999, 206:88-99. 10.1006/dbio.1998.9133, 9918697.
18. Smith GH, Boulanger CA. Mammary stem cell repertoire: new insights in aging epithelial populations. Mech Ageing Dev 2002, 123:1505-1519. 10.1016/S0047-6374(02)00114-8, 12425957.
19. Molyneux G, Regan J, Smalley MJ. Mammary stem cells and breast cancer. Cell Mol Life Sci 2007, 64:3248-3260. 10.1007/s00018-007-7391-5, 17955177.
20. Anderson E, Clarke RB. Steroid receptors and cell cycle in normal mammary epithelium. J Mammary Gland Biol Neoplasia 2004, 9:3-13. 10.1023/B:JOMG.0000023584.01750.16, 15082914.
21. Booth BW, Smith GH. Estrogen receptor-alpha and progesterone receptor are expressed in label-retaining mammary epithelial cells that divide asymmetrically and retain their template DNA strands. Breast Cancer Res 2006, 8:R49. 1779481, 16882347, 10.1186/bcr1538.
22. Traurig HH. A radioautographic study of cell proliferation in the mammary gland of the pregnant mouse. Anat Rec 1967, 159:239-247. 10.1002/ar.1091590213, 6082276.
23. Traurig HH, Morgan CF. Autoradiographic studies of the epithelium of mammary gland as influenced by ovarian hormones. Proc Soc Exp Biol Med 1964, 115:1076-1080.
24. Bresciani F. DNA synthesis in alveolar cells of the mammary gland: acceleration by ovarian hormones. Science 1964, 146:653-655. 10.1126/science.146.3644.653, 14191705.
25. Berman ME, Xie Y, Muller WA. Roles of platelet/endothelial cell adhesion molecule-1 (PECAM-1, CD31) in natural killer cell transendothelial migration and beta 2 integrin activation. J Immunol 1996, 156:1515-1524.
26. Kordon EC, Smith GH. An entire functional mammary gland may comprise the progeny from a single cell. Development 1998, 125:1921-1930.
27. Stingl J, Caldas C. Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis. Nat Rev Cancer 2007, 7:791-799. 10.1038/nrc2212, 17851544.
28. Smith GH, Medina D. A morphologically distinct candidate for an epithelial stem cell in mouse mammary gland. J Cell Sci 1988, 90:173-183.
29. Smith GH, Medina D. Re-evaluation of mammary stem cell biology based on in vivo transplantation. Breast Cancer Res 2008, 10:203. 2374966, 18304381, 10.1186/bcr1856.
30. Smith GH. Experimental mammary epithelial morphogenesis in an in vivo model: evidence for distinct cellular progenitors of the ductal and lobular phenotype. Breast Cancer Res Treat 1996, 39:21-31. 10.1007/BF01806075, 8738603.
31. Booth BW, Boulanger CA, Smith GH. Stem cells and the mammary microenvironment. Breast Disease, Birmingham: Metapress 2008,
32. Mallepell S, Krust A, Chambon P, Brisken C. Paracrine signaling through the epithelial estrogen receptor alpha is required for proliferation and morphogenesis in the mammary gland. Proc Natl Acad Sci USA 2006, 103:2196-2201. 1413744, 16452162, 10.1073/pnas.0510974103.
33. Asselin-Labat ML, Shackleton M, Stingl J, Vaillant F, Forrest NC, Eaves CJ, Visvader JE, Lindeman GJ. Steroid hormone receptor status of mouse mammary stem cells. J Natl Cancer Inst 2006, 98:1011-1014.
34. Clarke RB, Smith GH. Stem cells and tissue homeostasis in mammary glands. J Mammary Gland Biol Neoplasia 2005, 10:1-3. 10.1007/s10911-005-2535-4, 15886881.
35. Morroni M, Giordano A, Zingaretti MC, Boiani R, De Matteis R, Kahn BB, Nisoli E, Tonello C, Pisoschi C, Luchetti MM, Marelli M, Cinti S. Reversible transdifferentiation of secretory epithelial cells into adipocytes in the mammary gland. Proc Natl Acad Sci USA 2004, 101:16801-16806. 534744, 15556998, 10.1073/pnas.0407647101.
36. Djonov V, Andres AC, Ziemiecki A. Vascular remodelling during the normal and malignant life cycle of the mammary gland. Microsc Res Tech 2001, 52:182-189. 10.1002/1097-0029(20010115)52:2<182::AID-JEMT1004>3.0.CO;2-M, 11169866.