Cross-presentation of adeno-associated virus serotype 2 capsids activates cytotoxic T cells but does not render hepatocytes effective cytolytic targets

Human Gene Therapy

Volumn 18, Issue 3, 2007, Pages 185-194

  Wang, Lili ^a   Figueredo, Joanita ^a   Calcedo, Roberto ^a   Lin, Jianping ^a   Wilson, James M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; EPITOPE; PARVOVIRUS VECTOR;

ADENO ASSOCIATED VIRUS; ADENO ASSOCIATED VIRUS 2; ADENO ASSOCIATED VIRUS 7; ADENO ASSOCIATED VIRUS 8; ADOLESCENT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BAGG ALBINO MOUSE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CROSS PRESENTATION; CYTOKINE PRODUCTION; CYTOLYSIS; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; HEMOPHILIA; LIVER CELL; LIVER TOXICITY; LYMPHOCYTE ACTIVATION; MALE; MOUSE; NONHUMAN; SEROTYPE; VIRAL GENE THERAPY; VIRUS CAPSID;

AMINO ACID SEQUENCE; ANIMALS; CAPSID; CELL MOVEMENT; CROSS-PRIMING; CYTOTOXICITY TESTS, IMMUNOLOGIC; DEPENDOVIRUS; EPITOPE MAPPING; EPITOPES, T-LYMPHOCYTE; GENETIC VECTORS; HEPATOCYTES; LIVER; LYMPHOCYTE ACTIVATION; MICE; MOLECULAR SEQUENCE DATA; T-LYMPHOCYTES, CYTOTOXIC; TRANSDUCTION, GENETIC;

ADENO-ASSOCIATED VIRUS; ANIMALIA; MIRIDAE; MURINAE; MUS;

EID: 34247200575     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.2007.001     Document Type: Article

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