Acute localized administration of tetrahydrobiopterin and chronic systemic atorvastatin treatment restore cutaneous microvascular function in hypercholesterolaemic humans

Journal of Physiology

Volumn 589, Issue 19, 2011, Pages 4787-4797

  Holowatz, Lacy A ^a   Kenney, W Larry ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE; ATORVASTATIN; CHOLESTEROL; LOW DENSITY LIPOPROTEIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE; TETRAHYDROBIOPTERIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG EFFICACY; DRUG MECHANISM; ENZYME INHIBITION; FEMALE; HUMAN; HYPERCHOLESTEROLEMIA; MALE; MICROANGIOPATHY; MONOTHERAPY; PRIORITY JOURNAL; SKIN BLOOD FLOW; SKIN BLOOD VESSEL DISORDER; SKIN CONDUCTANCE; SKIN TEMPERATURE; TREATMENT DURATION; TREATMENT RESPONSE; VASODILATATION;

ANTICHOLESTEREMIC AGENTS; ARGINASE; ARGININE; BIOPTERIN; CHOLESTEROL; FEMALE; HEATING; HEPTANOIC ACIDS; HUMANS; HYPERCHOLESTEROLEMIA; LIPOPROTEINS, LDL; MALE; MICROCIRCULATION; MICRODIALYSIS; MIDDLE AGED; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; PYRROLES; REGIONAL BLOOD FLOW; SKIN; VASODILATION;

EID: 80053393924     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2011.212100     Document Type: Article

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