Role of nitric oxide in the vascular effects of local warming of the skin in humans

Journal of Applied Physiology

Volumn 86, Issue 4, 1999, Pages 1185-1190

  Kellogg Jr , D L ^a,b   Liu, Y ^b   Kosiba, I F ^b   O'Donnell, D ^b  

^a SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

Author keywords

Laser Doppler flowmetry; Microdialysis; Skin blood flow; Skin temperature; Vasodilation

Indexed keywords

N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE;

ADULT; ARTICLE; FEMALE; HUMAN; HUMAN EXPERIMENT; LASER DOPPLER FLOWMETRY; MALE; MEAN ARTERIAL PRESSURE; MICRODIALYSIS; NORMAL HUMAN; PRIORITY JOURNAL; SKIN BLOOD FLOW; SKIN CONDUCTANCE; SKIN TEMPERATURE; VASODILATATION;

EID: 0345059937     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/jappl.1999.86.4.1185     Document Type: Article

References (23)

1. Anderson, C., T. Andersson, and K. Wardell. Changes in skin circulation after insertion of a microdialysis probe visualized by laser-Doppler perfusion imaging. J. Invest. Dermatol. 102: 808-811, 1994.
2. Aulick, L. H., D. W. Wilmore, J. A. D. Mason, and J. B. A. Pruitt. Influence of the burn wound on peripheral circulation in thermally injured patients. Am. J. Physiol. 233 (Heart Circ. Physiol. 2): H520-H526, 1977.
3. Carberry, P. A., A. M. M. Shepherd, and J. M. Johnson. Resting and maximal forearm SkBF are reduced in hypertension. Hypertension 20: 349-355, 1992.
4. Coffman, J. D. Effects of endothelium-derived nitric oxide on skin and digital blood flow in humans. Am. J. Physiol. 267 (Heart Circ. Physiol. 36): H2087-H2090, 1994.
5. Cooke, J. P., J. T. Shepherd, and P. M. Vanhoutte. The effect of warming on adrenergic neurotransmission in canine cutaneous vein. Circ. Res. 54: 547-553, 1984.
6. Dietz, N. M., J. M. Rivera, D. O. Warner, and M. J. Joyner. Is nitric oxide involved in cutaneous vasodilation during body heating in humans? J. Appl. Physiol. 76: 2047-2053, 1994.
7. Edholm, O. G., R. H. Fox, and R. K. MacPherson. Vasomotor control of the cutaneous blood vessels in the human forearm. J. Physiol. (Lond.) 139: 455-465, 1957.
8. Farrell, D. M., and V. S. Bishop. Permissive role for nitric oxide in active thermoregulatory vasodilation in rabbit ear. Am. J. Physiol. 269 (Heart Circ. Physiol. 38): H1613-H1618, 1995.
9. Freund, P. R., G. L. Brengelmann, L. B. Rowell, L. Engrav, and D. M. Heinbach. Vasomotor control in healed grafted skin in humans. J. Appl. Physiol. 51: 168-171, 1981.
10. Goldsmith, P. C., T. A. Leslie, N. A. Hayes, N. J. Levell, P. M. Dowd, and J. C. Fremont. Inhibitors of nitric oxide synthase in human skin. J. Invest. Dermatol. 106: 113-118, 1996.
11. Johnson, J. M. The cutaneous circulation. In: Laser Doppler Blood Flowmetry, edited by A. Shepherd and P. Öberg. Boston, MA: Kluwer Academic, 1990, p. 121-140.
12. Johnson, J. M., D. S. O'Leary, W. F. Taylor, and W. Kosiba. Effect of local warming on forearm reactive hyperaemia. Clin. Physiol. 6: 337-346, 1986.
13. Kellogg, D. L., Jr., C. G. Crandall, Y. Liu, N. Charkoudian, and J. M. Johnson. Nitric oxide and cutaneous active vasodilation during heat stress in humans. J. Appl. Physiol. 85: 824-829, 1998.
14. Kellogg, D. L., Jr., P. E. Pérgola, W. A. Kosiba, M. Grossmann, and J. M. Johnson. Cutaneous active vasodilation in humans is mediated by cholinergic nerve co-transmission. Circ. Res. 77: 1222-1228, 1995.
15. Kreidstein, M. L., C. Y. Pang, L. N. Carlsen, and N. Xu. Evidence for endothelium-dependent and endothelium-independent vasodilation in human skin flaps. Can. J. Physiol. Pharmacol. 70: 1208-1216, 1992.
16. Noon, J. P., W. G. Haynes, D. J. Webb, and A. C. Shore. Local inhibition of nitric oxide generation in man reduces blood flow in finger pulp but not in hand dorsum skin. J. Physiol. (Lond.) 490: 501-508, 1996.
17. Pérgola, P. E., D. L. Kellogg, Jr., J. M. Johnson, and W. A. Kosiba. Role of sympathetic nerves in the vascular effects of local temperature in human forearm skin. Am. J. Physiol. 265 (Heart Circ. Physiol. 34): H785-H792, 1993.
18. Sandeman, D. D., C. A. Pym, E. M. Green, C. Seamark, A. C. Shore, and T. E. Tooke. Microvascular vasodilation in feet of newly diagnosed non-insulin dependent diabetic patients. Br. Med. J. 302: 1122-1123, 1991.
19. Saumet, J. L., D. L. Kellogg, Jr., W. F. Taylor, and J. M. Johnson. Cutaneous laser-Doppler flowmetry: influence of underlying muscle blood flow. J. Appl. Physiol. 65: 478-481, 1988.
20. Shastry, S., A. S. Reed, J. R. Halliwill, N. M. Dietz, and M. J. Joyner. Effects of nitric oxide synthase inhibition on cutaneous vasodilation during body heating in humans. J. Appl. Physiol. 85: 830-834, 1998.
21. Taylor, W. F., J. M. Johnson, D. O'Leary, and M. K. Park. Effect of high local temperature on reflex cutaneous vasodilation. J. Appl. Physiol. 57: 191-196, 1984.
22. Warren, J. B. Nitric oxide and human skin blood flow responses to acetylcholine and ultraviolet light. FASEB J. 8: 247-251, 1994.
23. Wenger, C. B., L. A. Stephenson, and M. A. Durkin. Effect of nerve block on response of forearm blood flow to local temperature. J. Appl. Physiol. 61: 227-232, 1986.