Combined anti-inflammatory effects of β2-adrenergic agonists and PDE4 inhibitors on astrocytes by upregulation of intracellular cAMP

Neurochemistry International

Volumn 59, Issue 6, 2011, Pages 837-846

  Christiansen, S H ^a,d   Selige, J ^b   Dunkern, T ^c   Rassov, A ^a,e   Leist, M ^a,b  

^a H LUNDBECK A S   (Denmark)

^b UNIVERSITY OF KONSTANZ   (Germany)

^c Nycomed GmbH   (Germany)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

^e Symphogen AS   (Denmark)

Author keywords

Astrocytes; cAMP; Inflammation; PDE4; Adrenoceptors

Indexed keywords

4 (3 BUTOXY 4 METHOXYBENZYL) 2 IMIDAZOLIDINONE; CLENBUTEROL; CYCLIC AMP; FORSKOLIN; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; ISOPRENALINE; MESSENGER RNA; MILRINONE; MONOCYTE CHEMOTACTIC PROTEIN 1; PHOSPHODIESTERASE III; PHOSPHODIESTERASE IV; ROLIPRAM; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTROCYTE; CELL LEVEL; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; INFLAMMATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION;

MURINAE;

EID: 80053342836     PISSN: 01970186     EISSN: 18729754     Source Type: Journal    
DOI: 10.1016/j.neuint.2011.08.012     Document Type: Article

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