Hyperthyroidism enhances 5-HT-induced contraction of the rat pulmonary artery: Role of calcium-activated chloride channel activation

European Journal of Pharmacology

Volumn 669, Issue 1-3, 2011, Pages 108-114

  Oriowo, Mabayoje A ^a   Oommen, Elsie ^a   Khan, Islam ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

5 HT; Ketanserin; Nifedipine; Niflumic acid; Pulmonary artery; Thyroxine

Indexed keywords

1 [5 (2 THIENYLMETHOXY) 3 INDOLYL] 2 PROPANAMINE; 3 (1,2,5,6 TETRAHYDRO 4 PYRIDYL)PYRROLO[3,2 B]PYRIDIN 5 ONE; KETANSERIN; NIFEDIPINE; NIFLUMIC ACID; SEROTONIN; SEROTONIN 2A RECEPTOR; THYROXINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERY CONSTRICTION; ARTICLE; CARDIOVASCULAR RESPONSE; CONCENTRATION RESPONSE; DRUG EFFICACY; DRUG INHIBITION; HYPERTHYROIDISM; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PULMONARY ARTERY; PULMONARY HYPERTENSION; RAT;

ANIMALS; CALCIUM; CHLORIDE CHANNELS; HYPERTENSION, PULMONARY; HYPERTHYROIDISM; MALE; PULMONARY ARTERY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, SEROTONIN, 5-HT2A; SEROTONIN; SEROTONIN AGENTS; SEROTONIN ANTAGONISTS; THYROXINE; VASOCONSTRICTION;

EID: 80053312273     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.07.002     Document Type: Article

References (39)

1. S. Adnot, B. Raffestin, S. Eddahibi, P. Braquet, and P.E. Chabrier Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia J. Clin. Invest. 87 1991 155 162
2. V.R. Alapati, C. McKenzie, A. Blair, D. Kenny, A. MacDonald, and A.M. Shaw Mechanisms of U 46619- and 5-HT-induced contraction of bovine pulmonary arteries: role of chloride ions Br. J. Pharmacol. 151 2007 1224 1334
3. O. Arunlakshana, and H.O. Schild Some quantitative uses of drug antagonists Br. J. Pharmacol. Chemother. 14 1959 48 58
4. 2B receptor antagonist in vitro and in vivo Br. J. Pharmacol. 143 2004 549 560 (Pubitemid 39524272)
5. C. Brink, C. Cerrina, C. Labat, J. Verley, and J. Benveniste The effect of contractile agonists on isolated pulmonary arterial and venous muscle preparations derived from patients with primary pulmonary hypertension Am. Rev. Respir. Dis. 137 1988 A106
6. L. Brown, J. Miller, A. Dagger, and C. Sernia Cardiac and vascular responses after monocrotaline-induced hypertrophy in rats J. Cardiovasc. Pharmacol. 31 1998 108 115 (Pubitemid 28027906)
7. A. Choppin, and S.E. O'Connor Presence of vasoconstrictor 5-HT1-like receptors revealed by precontraction of rabbit isolated mesenteric artery Br. J. Pharmacol. 114 1995 309 314
8. L.H. Clapp, J.L. Turner, and R.Z. Kolowski Ca(2+)-activated Cl- currents in pulmonary arterial myocytes Am. J. Physiol. 270 1996 H1577 H1584
9. D.N. Criddle, R. Soares de Moura, I.A. Greenwood, and W.A. Large Inhibitory action of niflumic acid on noradrenaline- and 5-hydroxytryptamine- induced pressor responses in the isolated mesenteric vascular bed of the rat Br. J. Pharmacol. 120 1997 813 818 (Pubitemid 27122720)
10. D. Cussac, A. Newman-Tancredi, Y. Quentric, N. Carpenter, G. Poissonnet, J.G. Parmentier, S. Goldstein, and M.J. Millan Characterization of phospholipase C activity at h5-HT2C compared with h5-HT2B receptors: influence of novel ligands upon membrane-bound levels of [3]phosphatidylinositols Naunyn Schmiedebergs Arch. Pharmacol. 365 2002 242 252 (Pubitemid 34212235)
11. G.A. Deuchar, M.N. Hicks, S.M. Cobbe, C.C. Docherty, and M.R. MacLean Pulmonary responses to 5-hydroxytryptamine and endothelin-1 in a rabbit model of left ventricular dysfunction Cardiovasc. Res. 38 1998 500 507 (Pubitemid 28294169)
12. P.F. Grassby, and J.H. McNeill The effect of hyperthyroidism on the responsiveness of the rat mesenteric artery to vasoactive agents Proc. West. Pharmacol. Soc. 29 1986 195 198 (Pubitemid 17169663)
13. D. Hoyer, D.E. Clarke, J.R. Fozard, P.R. Hartig, G.R. Martin, E.J. Mylecharane, P.R. Saxena, and P.P. Humphrey International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin) Pharmacol. Rev. 46 1994 157 203 (Pubitemid 24185150)
14. K.M. Ito, M. Sato, K. Ushijima, M. Nakai, and K. Ito Alterations of endothelium and smooth muscle function in monocrotaline-induced pulmonary hypertensive arteries Am. J. Physiol. 279 2000 H1786 H1795
15. 1B/1D-receptor antagonist GR 127935 Circ. Res. 89 2001 1231 1239 (Pubitemid 34627883)
16. W. Liang, J.B. Ray, J.Z. He, P.H. Backx, and M.E. Ward Regulation of proliferation and membrane potential by chloride currents in rat pulmonary artery smooth muscle cells Hypertension 54 2009 286 293
17. M.R. MacLean, G. Sweeney, M. Baird, K.M. McCulloch, M. Houslay, and I. Morecroft 5-Hydroxytryptamine receptors mediating vasoconstriction in pulmonary arteries from control and pulmonary hypertensive rats Br. J. Pharmacol. 119 1996 917 930 (Pubitemid 26366487)
18. M. Marvisi, P. Zambrelli, M. Brianti, G. Civardi, R. Lampugnani, and R. Delsignore Pulmonary hypertension is frequent in hyperthyroidism and normalizes after therapy Eur. J. Intern. Med. 17 2006 267 271 (Pubitemid 43817516)
19. K. Miyazawa, H. Hashimoto, and M. Nakashima Altered responsiveness of coronary arteries in hyperthyroid rats Arch. Int. Pharmacodyn. Ther. 297 1989 120 132 (Pubitemid 19066353)
20. E.J. Morcillo, and J. Cortijo Species differences in the responses of pulmonary vascular preparations to 5-hydroxytryptamine Therapie 54 1999 93 97 (Pubitemid 29145978)
21. I. Morecroft, and M.R. MacLean 5-Hydroxytryptamine receptors mediating vasoconstriction and vasodilation in perinatal and adult rabbit small pulmonary arteries Br. J. Pharmacol. 125 1998 69 78 (Pubitemid 28418758)
22. H. Nakazawa, M. Hori, H. Ozaki, and H. Karaki Mechanisms underlying the impairment of endothelium-dependent relaxation in the pulmonary artery of monocrotaline-induced pulmonary hypertensive rats Br. J. Pharmacol. 128 1999 1098 1104 (Pubitemid 29512044)
23. B. Nillius, J. Prenen, G. Szucs, L. Wei, F. Tanzi, T. Voets, and G. Droogmans Calcium-activated chloride channels in bovine pulmonary artery endothelial cells J. Physiol. 498 1997 381 396 (Pubitemid 27073383)
24. S.R. O'Donnell, and J.C. Wanstall Thyroxine treatment of aged or young rats demonstrates that vascular responses mediated by beta-adrenoceptor subtypes can be differentially regulated Br. J. Pharmacol. 88 1986 41 49 (Pubitemid 16020775)
25. S.R. O'Donnell, J.C. Wanstall, and M.B. Mustafa Influence of thyroid status on responses of rat isolated pulmonary artery, vas deferens and trachea to smooth muscle relaxant drugs Br. J. Pharmacol. 92 1987 221 229 (Pubitemid 17134938)
26. H. Okura, and Y. Takatsu High-output heart failure as a cause of pulmonary hypertension Intern. Med. 33 1994 363 365
27. 1-adrenoceptor mediated pulmonary artery smooth muscle contraction: effect of pulmonary hypertension Eur. J. Pharmacol. 506 2004 157 163 (Pubitemid 39592913)
28. L. Rodat-Despoix, H. Crevel, R. Marthan, J.P. Savineau, and C. Guibert Heterogeneity in 5-HT-induced contractile and proliferative responses in rat pulmonary arterial bed J. Vasc. Res. 45 2008 181 192 (Pubitemid 351543142)
29. L. Rodat-Despoix, V. Aires, T. Ducret, R. Marthan, J.P. Savineau, E. Rousseau, and C. Guibert Signalling pathways involved in the contractile response to 5-HT in the human pulmonary artery Eur. Respir. J. 34 2009 1338 1347
30. A. Russell, A. Banes, H. Berlin, G.D. Fink, and S.W. Watts 5-Hydroxytryptamine(2B) receptor function is enhanced in the N(omega)-nitro-L-arginine hypertensive rat J. Pharmacol. Exp. Ther. 303 2002 179 187
31. H.C. Scarparo, G.C. Santos, J.H. Leal-Cardoso, and D.N. Criddle Selective inhibitory effects of niflumic acid on 5-HT-induced contraction of the rat isolated stomach fundus Br. J. Pharmacol. 130 2000 678 684 (Pubitemid 30332988)
32. M.C.L. Teixeira, R.R. Coelho, J.H. Leal-Cardoso, and D.N. Criddle Comparative effects of niflumic acid and nifedipine on 5-hydroxytryptamine- and acetylcholine-induced contraction of the rat trachea Eur. J. Pharmacol. 394 2000 117 122 (Pubitemid 30193297)
33. S.S. Virani, C.E. Mendoza, A.C. Ferreira, and E. De Marchena Grave's disease and pulmonary hypertension: report of 2 cases Tex. Heart Inst. J. 30 2003 314 315 (Pubitemid 37499755)
34. 1B receptor augmented 5-HT vasoconstrictor response of pulmonary artery in monocrotaline-induced pulmonary hypertensive rats Acta Pharmacol. Sin. 22 2001 269 273 (Pubitemid 32221500)
35. S.W. Watts Serotonin-induced contraction in mesenteric resistance arteries: signaling and changes in deoxycorticosterone acetate-salt hypertension Hypertension 39 2002 825 829 (Pubitemid 34252884)
36. S.W. Watts, M. Baez, and R.C. Webb The 5-hydroxytryptamine 2B receptor and 5-HT receptor signal transduction in mesenteric arteries from deoxycorticosterone acetate-salt hypertensive rats J. Pharmacol. Exp. Ther. 227 1996 1103 1113
37. M.M. White, and M. Aylwin Niflumic and flufenamic acids are potent reversible blockers of Ca2(+)-activated Cl-channels in Xenopus oocytes Mol. Pharmacol. 37 1990 720 724 (Pubitemid 20171508)
38. X.J. Yuan Role of calcium-activated chloride current in regulating pulmonary vasomotor tone Am. J. Physiol. 272 1997 L959 L968
39. J. Zwaveling, E.A. WinklerPrins, M. Pfaffendorf, and P.A. Van Zwitten The influence of hyperthyroidism on beta-adrenoceptor-mediated relaxation of isolated small mesenteric arteries Naunyn Schmiedebergs Arch. Pharmacol. 353 1996 438 444