1,3-substituted imidazolidine-2,4,5-triones: Synthesis and inhibition of cholinergic enzymes

Molecules

Volumn 16, Issue 9, 2011, Pages 7565-7582

  Pejchal, Vladimir ^a   Stepankova, Sarka ^a   Padelkova, Zdenka ^a   Imramovsky, Ales ^a   Jampilek, Josef ^b  

^a UNIVERSITY OF PARDUBICE   (Czech Republic)

^b UNIVERSITY OF VETERINARY AND PHARMACEUTICAL SCIENCES   (Czech Republic)

Author keywords

1 (aryl) 3 (R) 1 (6 fluorobenzo d thiazol 2 yl)ethyl imidazolidine 2,4, 5 triones; In vitro acetylcholinesterase inhibition; In vitro butyrylcholinesterase inhibition; Lipophilicity; Structure activity relationships; X ray diffraction

Indexed keywords

ACETYLCHOLINESTERASE; BENZOTHIAZOLE DERIVATIVE; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; IMIDAZOLIDINE DERIVATIVE;

ARTICLE; CHEMICAL PHENOMENA; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; ENZYME ASSAY; REFERENCE VALUE; STRUCTURE ACTIVITY RELATION; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

ACETYLCHOLINESTERASE; BENZOTHIAZOLES; BUTYRYLCHOLINESTERASE; CHOLINESTERASE INHIBITORS; CRYSTALLOGRAPHY, X-RAY; ENZYME ASSAYS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; IMIDAZOLIDINES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; REFERENCE VALUES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 80053281946     PISSN: None     EISSN: 14203049     Source Type: Journal    
DOI: 10.3390/molecules16097565     Document Type: Article

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