Opalescence of an IgG2 monoclonal antibody solution as it relates to liquid-liquid phase separation

Journal of Pharmaceutical Sciences

Volumn 100, Issue 11, 2011, Pages 4587-4596

  Mason, Bruce D ^a   Zhang, Le ^a   Remmele, Richard L ^a   Zhang, Jifeng ^a  

^a AMGEN INC   (United States)

Author keywords

Biopharmaceuticals characterization; Biotechnology; Formulation; Light scattering; Phase transition; Protein formulation; Protein stability

Indexed keywords

IMMUNOGLOBULIN G2;

ARTICLE; CHEMICAL PARAMETERS; CONTROLLED STUDY; DRUG SOLUBILITY; IONIC STRENGTH; LIQUID LIQUID EXTRACTION; NONHUMAN; OPALESCENCE; PH; PROTEIN PROTEIN INTERACTION; TEMPERATURE; TURBIDITY;

EID: 80053232304     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22650     Document Type: Article

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