The antiproliferative function of violacein-like purple violet pigment (PVP) from an Antarctic Janthinobacterium sp. Ant5-2 in UV-induced 2237 fibrosarcoma

International Journal of Dermatology

Volumn 50, Issue 10, 2011, Pages 1223-1233

  Mojib, Nazia ^a   Nasti, Tahseen H ^a   Andersen, Dale T ^b   Attigada, Venkatram R ^a   Hoover, Richard B ^c   Yusuf, Nabiha ^a   Bej, Asim K ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b SETI INSTITUTE   (United States)

^c NASA MARSHALL SPACE FLIGHT CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 9; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; CYTOCHROME C; NATURAL PRODUCT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PROTEIN BAX; PROTEIN BCL 2; PURPLE VIOLET PIGMENT; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BACTERIUM; CANCER CELL CULTURE; CELL CYCLE ARREST; CELL PROLIFERATION; CELL VIABILITY; ENZYME ACTIVITY; FIBROSARCOMA; IN VITRO STUDY; JANTHINOBACTERIUM; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PROTEIN EXPRESSION; ULTRAVIOLET RADIATION;

ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASES; CYTOCHROMES C; FIBROSARCOMA; INDOLES; MELANOMA; MELANOMA, EXPERIMENTAL; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; OXALOBACTERACEAE; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; SKIN NEOPLASMS;

EID: 80053198409     PISSN: 00119059     EISSN: 13654632     Source Type: Journal    
DOI: 10.1111/j.1365-4632.2010.04825.x     Document Type: Article

References (22)

1. Meeran SM, Katiyar S, Elmets CA, Katiyar SK. Interleukin-12 deficiency is permissive for angiogenesis in UV radiation-induced skin tumors. Cancer Res 2007; 67: 3785-3793.
2. Saladi RN, Persaud AN. The causes of skin cancer: a comprehensive review. Drugs Today (Barc) 2005; 41: 37-53.
3. Katiyar S, Elmets CA, Katiyar SK. Green tea and skin cancer: photoimmunology, angiogenesis and DNA repair. J Nutr Biochem 2007; 18: 287-296.
4. Yusuf N, Nasti TH, Meleth S, Elmets CA. Resveratrol enhances cell-mediated immune response to DMBA through TLR4 and prevents DMBA induced cutaneous carcinogenesis. Mol Carcinog 2009; 48: 713-723.
5. Katiyar SK. Grape seed proanthocyanidines and skin cancer prevention: inhibition of oxidative stress and protection of immune system. Mol Nutr Food Res 2008; 52(Suppl 1): S71-S76.
6. Konishi M, Hatori M, Tomita K, et al. Chicamycin, a new antitumor antibiotic I. Production, isolation and properties. J Antibiot (Tokyo) 1984; 37: 191-199.
7. Rettori D, Duran N. Production, extraction and purification of violacein: an antibiotic produced by Chromobacterium violaceum. World J Microbiol Biotechnol 1998; 14: 685-688.
8. Duran N, Menck CF. Chromobacterium violaceum: a review of pharmacological and industrial perspectives. Crit Rev Microbiol 2001; 27: 201-222.
9. Melo PS, Justo GZ, de Azevedo MB, et al. Violacein and its beta-cyclodextrin complexes induce apoptosis and differentiation in HL60 cells. Toxicology 2003; 186: 217-225.
10. Ferreira CV, Bos CL, Versteeg HH, et al. Molecular mechanism of violacein-mediated human leukemia cell death. Blood 2004; 104: 1459-1464.
11. de Carvalho DD, Costa FT, Duran N, et al. Cytotoxic activity of violacein in human colon cancer cells. Toxicol In Vitro 2006; 20: 1514-1521.
12. Khan N, Afaq F, Kweon MH, et al. Oral consumption of pomegranate fruit extract inhibits growth and progression of primary lung tumors in mice. Cancer Res 2007; 67: 3475-3482.
13. Mojib N, Philpott R, Huang JP, et al. Antimycobacterial activity in vitro of pigments isolated from Antarctic bacteria. Antonie Van Leeuwenhoek 2010; 98: 531-540.
14. Zhu Z, Hotchkiss SA, Boobis AR, Edwards RJ. Expression of P450 enzymes in rat whole skin and cultured epidermal keratinocytes. Biochem Biophys Res Commun 2002; 297: 65-70.
15. Hengartner MO. The biochemistry of apoptosis. Nature 2000; 407: 770-776.
16. Taraphdar AK, Roy M, Bhattacharya RK. Natural products as inducers of apoptosis: Implication for cancer therapy and prevention. Current Science 2001; 80: 1387-1396.
17. Molinari M. Cell cycle checkpoints and their inactivation in human cancer. Cell Prolif 2000; 33: 261-274.
18. Flatt PM, Tang LJ, Scatena CD, et al. p53 regulation of G(2) checkpoint is retinoblastoma protein dependent. Mol Cell Biol 2000; 20: 4210-4223.
19. Bunz F, Dutriaux A, Lengauer C, et al. Requirement for p53 and p21 to sustain G2 arrest after DNA damage. Science 1998; 282: 1497-1501.
20. Tang X, Zhu Y, Han L, et al. CP-31398 restores mutant p53 tumor suppressor function and inhibits UVB-induced skin carcinogenesis in mice. J Clin Invest 2007; 117: 3753-3764.
21. Melnikova VO, Santamaria AB, Bolshakov SB, Ananthaswamy HN. Mutant p53 is constitutively phosphorylated at Serine 15 in UV-induced mouse skin tumors: involvement of ERK1/2 MAP kinase. Oncogene 2003; 22: 5958-5966.
22. Gross A, McDonnell JM, Korsmeyer SJ. BCL-2 family members and the mitochondria in apoptosis. Genes Dev 1999; 13: 1899-11.