Production, extraction and purification of violacein: An antibiotic pigment produced by Chromobacterium violaceum

World Journal of Microbiology and Biotechnology

Volumn 14, Issue 5, 1998, Pages 685-688

  Rettori, D ^a   Duran N ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Antibiotic; Bioreactor; Chromobacterium violaceum; Pigment; Violacein

Indexed keywords

ALCOHOL; ANTIBIOTIC PRODUCTION; BACTERIAL BIOSYNTHESIS; BACTERIAL METABOLISM; BIOREACTOR; CHROMOBACTERIUM VIOLACEUM; COTTON; CRYSTALLIZATION; CULTIVATION; DRUG PURIFICATION; EXTRACTION; FILTRATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROSCOPY; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; THERMOGRAVIMETRY; ULTRAVIOLET SPECTROSCOPY; VIOLACEIN;

EID: 0031737387     PISSN: 09593993     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008809504504     Document Type: Article

References (16)

1. Bycroft, B.W. 1988 Dictionary of Antibiotics and Related Substances. London: Chapman and Hall, pp. 733.
2. Caldas, L.R., Leitão, A.A.C., Santos, S.M. & Tyrrell, R.M. 1978 Preliminary experiments on the photobiological properties of violacein. In Proceedings of International Symposium on Current Topics in Radiology and Photobiology, ed Tyrrell, R.M. pp. 121-126. Rio de Janeiro: Academia Brasileira de Ciências.
3. Durán, N., Erazo, S. & Campos, V. 1983 Bacterial chemistry-II: antimicrobial photoproduct from pigment of Chromobacterium violaceum. Anais da Academia Brasileira de Ciências 55, 231-234.
4. Durán, N., Antonio, R.V., Haun, M. & Pilli, R.A. 1994 Biosynthesis of a trypanocide by Chromobacterium violaceum. World Journal of Microbiology and Biotechnology 10, 686-690.
5. Durán, N., Melo, P.S. & Haun, M. 1996 In vitro evaluation of violacein on AIDS-related lymphoma and human tumor cell lines. In XXV Annual Meetings of the Brazilian Society of Biochemistry and Molecular Biology, pp. 150. Caxambu: Sociedade Brasileira de Bioquímica e Biologia Molecular (SBBq).
6. Hoshino, T., Kondo, T., Uchiyama, T. & Ogasawara, N. 1987 Biosynthesis of violacein: a novel rearrangement in tryptophan metabolism with a 1,2-shift of the indole ring. Agricultural and Biological Chemistry 51, 965-968.
7. Kaufman, S.C., Ceraso, D. & Schugurensky, A. 1986 First case report from Argentina of fatal septicemia caused by Chromobacterium violaceum. Journal of Clinical Microbiology 23, 956-958.
8. Laatsch, H., Thomson, T.H. & Cox, P.J. 1984 Spectroscopic properties of violacein and related compounds: crystal structure of tetramethylviolacein. Journal of the Chemical Society, Perkin Transactions II, 1331-1339.
9. Lichstein, H.C. & Van de Sand, V.F. 1945 Violacein, an antibiotic pigment produced by Chromobacterium violaceum. Journal of Infectious Diseases 76, 47-51.
10. May, G., Brümmer, B. & Ott, H. 1991 Verfahren zur isolierung von violacein und seine verwendung zur prophylaxe und therapie von viruserkrankungen. Deutsches Patentamt Offenlegungsschrift DE 3,935,066 (CL.C12P17/16), 25 April 1991, Application. 20 October 1989, 5pp.
11. Melo, P.S. 1996 Pigmentos obtidos de Chromobacterium violaceum e Serratia marcescens, Propriedade tripanocida da prodigiosina e estudos toxicológicos. Masters Thesis, Biology Institute, Campinas State University, Campinas, SP, Brazil.
12. Perkampus, H.H., Sandeman, I. & Timmons, C.J. 1971 UV Atlas of Organic Compounds. London: Butterworth, Vol. 5, spectrum number 5812.
13. Ponte, R. & Jenkins, S.G. 1992 Fatal Chromobacterium violaceum infections associated with exposure to stagnant waters. The Pediatric Infectious Disease Journal 11, 583-586.
14. Rettori, D. 1996 Producção, extração e purificação da violaceína: um antibiótico produzido pela Chromobacterium violaceum. Masters Thesis. Chemistry Institute, Campinas State Univeristy, Campinas, SP, Brazil.
15. Rettori, D. & Durán, N. 1997 Um biorreator de prateleiras para superficies (BPS) para a produção de um metabolito bacteriano. Brazilian Patent P19702986-6.
16. Riveros, R., Haun, M., Campos, V. & Durán, N. 1988 Bacterial Chemistry-IV. Complete characterization of violacein: an antibiotic and trypanocide pigment from Chromobacterium violaceum. Arquivos de Biologia e Tecnologia (Brazil) 31, 475-487.