메뉴 건너뛰기




Volumn 67, Issue 7, 2007, Pages 3475-3482

Oral consumption of pomegranate fruit extract inhibits growth and progression of primary lung tumors in mice

Author keywords

[No Author keywords available]

Indexed keywords

BENZO[A]PYRENE; CARCINOGEN; CD31 ANTIGEN; CYCLINE; I KAPPA B ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; KI 67 ANTIGEN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE 9; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P110; PROTEIN P85; SCATTER FACTOR RECEPTOR; STRESS ACTIVATED PROTEIN KINASE 1; THREONINE; VASCULOTROPIN; ANTINEOPLASTIC AGENT; DRUG DERIVATIVE; I KAPPA B; I KAPPA B KINASE; MITOGEN ACTIVATED PROTEIN KINASE; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; PLANT EXTRACT; PROTEIN KINASE; UNCLASSIFIED DRUG; UREA;

EID: 34248215034     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-06-3941     Document Type: Article
Times cited : (158)

References (29)
  • 2
    • 33244454723 scopus 로고    scopus 로고
    • Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells
    • Adams LS, Seeram NP, Aggarwal BB, Takada Y, Sand D, Heber D. Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells. J Agric Food Chem 2006;54:980-5.
    • (2006) J Agric Food Chem , vol.54 , pp. 980-985
    • Adams, L.S.1    Seeram, N.P.2    Aggarwal, B.B.3    Takada, Y.4    Sand, D.5    Heber, D.6
  • 3
    • 0036201937 scopus 로고    scopus 로고
    • Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer
    • Kim ND, Mehta R, Yu W, et al. Chemopreventive and adjuvant therapeutic potential of pomegranate (Punica granatum) for human breast cancer. Breast Cancer Res Treat 2002;71:203-17.
    • (2002) Breast Cancer Res Treat , vol.71 , pp. 203-217
    • Kim, N.D.1    Mehta, R.2    Yu, W.3
  • 4
    • 33746795022 scopus 로고    scopus 로고
    • Pomegranate juice protects nitric oxide against oxidative destruction and enhances the biological actions of nitric oxide
    • Ignarro LJ, Byrns RE, Sumi D, de Nigris F, Napoli C. Pomegranate juice protects nitric oxide against oxidative destruction and enhances the biological actions of nitric oxide. Nitric Oxide 2006;15:93-102.
    • (2006) Nitric Oxide , vol.15 , pp. 93-102
    • Ignarro, L.J.1    Byrns, R.E.2    Sumi, D.3    de Nigris, F.4    Napoli, C.5
  • 5
    • 33749065777 scopus 로고    scopus 로고
    • Pomegranate juice reduces oxidized low-density lipoprotein downregulation of endothelial nitric oxide synthase in human coronary endothelial cells
    • de Nigris F, Williams-Ignarro S, Botti C, Sica V, Ignarro LJ, Napoli C. Pomegranate juice reduces oxidized low-density lipoprotein downregulation of endothelial nitric oxide synthase in human coronary endothelial cells. Nitric Oxide 2006;15:259-63.
    • (2006) Nitric Oxide , vol.15 , pp. 259-263
    • de Nigris, F.1    Williams-Ignarro, S.2    Botti, C.3    Sica, V.4    Ignarro, L.J.5    Napoli, C.6
  • 6
    • 0033788223 scopus 로고    scopus 로고
    • Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing
    • Gil MI, Tomas-Barberan FA, Hess-Pierce B, Holcroft DM, Kedar AA. Antioxidant activity of pomegranate juice and its relationship with phenolic composition and processing. J Agric Food Chem 2000;10:4581-9.
    • (2000) J Agric Food Chem , vol.10 , pp. 4581-4589
    • Gil, M.I.1    Tomas-Barberan, F.A.2    Hess-Pierce, B.3    Holcroft, D.M.4    Kedar, A.A.5
  • 7
    • 11144335895 scopus 로고    scopus 로고
    • Anthocyanin and hydrolyzable tannin-rich pomegranate fruit extract modulates MAPK and NF-κB pathways and inhibits skin tumorigenesis in CD-1 mice
    • Afaq F, Saleem M, Krueger CG, Reed JD, Mukhtar H. Anthocyanin and hydrolyzable tannin-rich pomegranate fruit extract modulates MAPK and NF-κB pathways and inhibits skin tumorigenesis in CD-1 mice. Int J Cancer 2005;113:423-33.
    • (2005) Int J Cancer , vol.113 , pp. 423-433
    • Afaq, F.1    Saleem, M.2    Krueger, C.G.3    Reed, J.D.4    Mukhtar, H.5
  • 9
    • 14744277141 scopus 로고    scopus 로고
    • Pomegranate fruit extract modulates UV-B-mediated phosphorylation of mitogen-activated protein kinases and activation of nuclear factor κB in normal human epidermal keratinocytes paragraph sign
    • Afaq F, Malik A, Syed D, Maes D, Matsui MS, Mukhtar H. Pomegranate fruit extract modulates UV-B-mediated phosphorylation of mitogen-activated protein kinases and activation of nuclear factor κB in normal human epidermal keratinocytes paragraph sign. Photochem Photobiol 2005;81:38-45.
    • (2005) Photochem Photobiol , vol.81 , pp. 38-45
    • Afaq, F.1    Malik, A.2    Syed, D.3    Maes, D.4    Matsui, M.S.5    Mukhtar, H.6
  • 10
    • 33646268191 scopus 로고    scopus 로고
    • Photochemopreventive effect of pomegranate fruit extract on UVA-mediated activation of cellular pathways in normal human epidermal keratinocytes
    • Syed DN, Malik A, Hadi N, Sarfaraz S, Afaq F, Mukhtar H. Photochemopreventive effect of pomegranate fruit extract on UVA-mediated activation of cellular pathways in normal human epidermal keratinocytes. Photochem Photobiol 2006;82:398-405.
    • (2006) Photochem Photobiol , vol.82 , pp. 398-405
    • Syed, D.N.1    Malik, A.2    Hadi, N.3    Sarfaraz, S.4    Afaq, F.5    Mukhtar, H.6
  • 11
    • 33845612815 scopus 로고    scopus 로고
    • Pomegranate fruit extract inhibits prosurvival pathways in human A549 lung carcinoma cells and tumor growth in athymic nude mice
    • Khan N, Hadi N, Afaq F, Syed DN, Kweon MH, Mukhtar H. Pomegranate fruit extract inhibits prosurvival pathways in human A549 lung carcinoma cells and tumor growth in athymic nude mice. Carcinogenesis 2007;28:163-73.
    • (2007) Carcinogenesis , vol.28 , pp. 163-173
    • Khan, N.1    Hadi, N.2    Afaq, F.3    Syed, D.N.4    Kweon, M.H.5    Mukhtar, H.6
  • 12
    • 33746073732 scopus 로고    scopus 로고
    • Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for prostate cancer
    • Pantuck AJ, Leppert JT, Zomorodian N, et al. Phase II study of pomegranate juice for men with rising prostate-specific antigen following surgery or radiation for prostate cancer. Clin Cancer Res 2006;12:4018-26.
    • (2006) Clin Cancer Res , vol.12 , pp. 4018-4026
    • Pantuck, A.J.1    Leppert, J.T.2    Zomorodian, N.3
  • 13
    • 0142228320 scopus 로고    scopus 로고
    • Tobacco carcinogens, their biomarkers and tobacco-induced cancer
    • Hecht SS. Tobacco carcinogens, their biomarkers and tobacco-induced cancer. Nat Rev Cancer 2003;3:733-44.
    • (2003) Nat Rev Cancer , vol.3 , pp. 733-744
    • Hecht, S.S.1
  • 14
    • 1642363983 scopus 로고    scopus 로고
    • A chemically induced model for squamous cell carcinoma of the lung in mice: Histopathology and strain susceptibility
    • Wang Y, Zhang Z, Yan Y, et al. A chemically induced model for squamous cell carcinoma of the lung in mice: histopathology and strain susceptibility. Cancer Res 2004;64:1647-54.
    • (2004) Cancer Res , vol.64 , pp. 1647-1654
    • Wang, Y.1    Zhang, Z.2    Yan, Y.3
  • 15
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-κB in cancer development and progression
    • Karin M. Nuclear factor-κB in cancer development and progression. Nature 2006;441:431-6.
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 16
    • 33745530860 scopus 로고    scopus 로고
    • The many paths to p38 mitogen-activated protein kinase activation in the immune system
    • Ashwell JD. The many paths to p38 mitogen-activated protein kinase activation in the immune system. Nat Rev Immunol 2006;6:532-40.
    • (2006) Nat Rev Immunol , vol.6 , pp. 532-540
    • Ashwell, J.D.1
  • 18
    • 27944452718 scopus 로고    scopus 로고
    • Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis
    • Lee HY, Oh SH, Woo JK, et al. Chemopreventive effects of deguelin, a novel Akt inhibitor, on tobacco-induced lung tumorigenesis. J Natl Cancer Inst 2005;97:1695-9.
    • (2005) J Natl Cancer Inst , vol.97 , pp. 1695-1699
    • Lee, H.Y.1    Oh, S.H.2    Woo, J.K.3
  • 19
    • 33746637660 scopus 로고    scopus 로고
    • Current development of mTOR inhibitors as anticancer agents
    • Faivre S, Kroemer G, Raymond E. Current development of mTOR inhibitors as anticancer agents. Nat Rev Drug Discov 2006;5:671-88.
    • (2006) Nat Rev Drug Discov , vol.5 , pp. 671-688
    • Faivre, S.1    Kroemer, G.2    Raymond, E.3
  • 20
    • 31544464931 scopus 로고    scopus 로고
    • Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways
    • Han S, Khuri FR, Roman J. Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways. Cancer Res 2006;66:315-23.
    • (2006) Cancer Res , vol.66 , pp. 315-323
    • Han, S.1    Khuri, F.R.2    Roman, J.3
  • 21
    • 4444278397 scopus 로고    scopus 로고
    • Overexpressed eIF4E is functionally active in surgical margins of head and neck cancer patients via activation of the Akt/mammalian target of rapamycin pathway
    • Nathan CA, Amirghahari N, Abreo F, et al. Overexpressed eIF4E is functionally active in surgical margins of head and neck cancer patients via activation of the Akt/mammalian target of rapamycin pathway. Clin Cancer Res 2004;10:5820-7.
    • (2004) Clin Cancer Res , vol.10 , pp. 5820-5827
    • Nathan, C.A.1    Amirghahari, N.2    Abreo, F.3
  • 22
    • 25444524850 scopus 로고    scopus 로고
    • Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity
    • Hahn-Windgassen A, Nogueira V, Chen CC, Skeen JE, Sonenberg N, Hay N. Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity. J Biol Chem 2005;280:32081-9.
    • (2005) J Biol Chem , vol.280 , pp. 32081-32089
    • Hahn-Windgassen, A.1    Nogueira, V.2    Chen, C.C.3    Skeen, J.E.4    Sonenberg, N.5    Hay, N.6
  • 23
    • 0029160069 scopus 로고
    • Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction
    • Burgering BM, Coffer PJ. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction. Nature 1995;376:599-602.
    • (1995) Nature , vol.376 , pp. 599-602
    • Burgering, B.M.1    Coffer, P.J.2
  • 24
    • 33745213627 scopus 로고    scopus 로고
    • AMPK and cell proliferation-AMPK as a therapeutic target for atherosclerosis and cancer
    • Motoshima H, Goldstein BJ, Igata M, Araki E. AMPK and cell proliferation-AMPK as a therapeutic target for atherosclerosis and cancer. J Physiol 2006;574:63-71.
    • (2006) J Physiol , vol.574 , pp. 63-71
    • Motoshima, H.1    Goldstein, B.J.2    Igata, M.3    Araki, E.4
  • 25
    • 13944276728 scopus 로고    scopus 로고
    • Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer
    • Ma PC, Jagadeeswaran R, Jagadeesh S, et al. Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer. Cancer Res 2005;65:1479-88.
    • (2005) Cancer Res , vol.65 , pp. 1479-1488
    • Ma, P.C.1    Jagadeeswaran, R.2    Jagadeesh, S.3
  • 26
    • 0033566973 scopus 로고    scopus 로고
    • Abnormal regulation of DNA methyltransferase expression during colorectal carcinogenesis
    • De Marzo AM, Marchi VL, Yang ES, Veeraswamy R, Lin X, Nelson WG. Abnormal regulation of DNA methyltransferase expression during colorectal carcinogenesis. Cancer Res 1999;59:3855-60.
    • (1999) Cancer Res , vol.59 , pp. 3855-3860
    • De Marzo, A.M.1    Marchi, V.L.2    Yang, E.S.3    Veeraswamy, R.4    Lin, X.5    Nelson, W.G.6
  • 27
    • 0034488632 scopus 로고    scopus 로고
    • Nitric oxide synthase, cyclooxygenase 2, and vascular endothelial growth factor in the angiogenesis of non-small cell lung carcinoma
    • Marrogi AJ, Travis WD, Welsh JA, Khan MA, Rahim H, Tazelaar H. Nitric oxide synthase, cyclooxygenase 2, and vascular endothelial growth factor in the angiogenesis of non-small cell lung carcinoma. Clin Cancer Res 2000;6:4739-44.
    • (2000) Clin Cancer Res , vol.6 , pp. 4739-4744
    • Marrogi, A.J.1    Travis, W.D.2    Welsh, J.A.3    Khan, M.A.4    Rahim, H.5    Tazelaar, H.6
  • 28
    • 33746776975 scopus 로고    scopus 로고
    • Effect of connective tissue growth factor on hypoxia-inducible factor 1α degradation and tumor angiogenesis
    • Chang CC, Lin MT, Lin BR, et al. Effect of connective tissue growth factor on hypoxia-inducible factor 1α degradation and tumor angiogenesis. J Natl Cancer Inst 2006;98:984-5.
    • (2006) J Natl Cancer Inst , vol.98 , pp. 984-985
    • Chang, C.C.1    Lin, M.T.2    Lin, B.R.3
  • 29
    • 23844545810 scopus 로고    scopus 로고
    • Platelet-derived growth factor-AA is an essential and autocrine regulator of vascular endothelial growth factor expression in non-small cell lung carcinomas
    • Shikada Y, Yonemitsu Y, Koga T, et al. Platelet-derived growth factor-AA is an essential and autocrine regulator of vascular endothelial growth factor expression in non-small cell lung carcinomas. Cancer Res 2005;65:7241-8.
    • (2005) Cancer Res , vol.65 , pp. 7241-7248
    • Shikada, Y.1    Yonemitsu, Y.2    Koga, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.