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Volumn 26, Issue 10, 2011, Pages 2473-2485

Parathyroid hormone signaling via Gαs is selectively inhibited by an NH 2-terminally truncated Gαs: Implications for pseudohypoparathyroidism

Author keywords

albright hereditary osteodystrophy; cyclic AMP; parathyroid hormone; pseudohypoparathyroidism; stimulatory G protein

Indexed keywords

ADENYLATE CYCLASE; ARGIPRESSIN RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; CYCLIC AMP; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; ISOPRENALINE; LEVOTHYROXINE; PARATHYROID HORMONE; PARATHYROID HORMONE RECEPTOR 1; THYROTROPIN RECEPTOR;

EID: 80053178756     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.461     Document Type: Article
Times cited : (37)

References (46)
  • 1
    • 36248940652 scopus 로고    scopus 로고
    • Perspectives: Pseudohypoparathyroidism, Gsα, and the GNAS locus
    • Bastepe M, Jüppner H,. Perspectives: pseudohypoparathyroidism, Gsα, and the GNAS locus. BoneKEy-Osteovision. 2005; 2: 20-32.
    • (2005) BoneKEy-Osteovision. , vol.2 , pp. 20-32
    • Bastepe, M.1    Jüppner, H.2
  • 2
    • 0005371412 scopus 로고    scopus 로고
    • J.P. Bilezikian, L.G. Raisz, G.A. Rodan, eds. Principles of bone biology, vol. New York: Academic Press
    • Levine MA., Pseudohypoparathyroidism. In:, JP Bilezikian, LG Raisz, GA Rodan, eds. Principles of bone biology, vol 2. New York: Academic Press; 2002, pp 1137-63.
    • (2002) Pseudohypoparathyroidism. , vol.2 , pp. 1137-1163
    • Levine, M.A.1
  • 3
    • 0000821313 scopus 로고
    • Pseudohypoparathyroidism: An example of "seabright-Bantam syndrome
    • Albright F, Burnett CH, Smith PH,. Pseudohypoparathyroidism: an example of "Seabright-Bantam syndrome." Endocrinology. 1942; 30: 922-32.
    • (1942) Endocrinology. , vol.30 , pp. 922-932
    • Albright, F.1    Burnett, C.H.2    Smith, P.H.3
  • 5
    • 0034793851 scopus 로고    scopus 로고
    • Endocrine manifestations of stimulatory G protein α subunit mutations and the role of genomic imprinting
    • DOI 10.1210/er.22.5.675
    • Weinstein LS, Yu S, Warner DR, Liu J,. Endocrine manifestations of stimulatory G protein α-subunit mutations and the role of genomic imprinting. Endocr Rev. 2001; 22: 675-705. (Pubitemid 32955250)
    • (2001) Endocrine Reviews , vol.22 , Issue.5 , pp. 675-705
    • Weinstein, L.S.1    Yu, S.2    Warner, D.R.3    Liu, J.4
  • 8
    • 0035362592 scopus 로고    scopus 로고
    • Positional dissociation between the genetic mutation responsible for pseudohypoparathyroidusm type 1b and the associated methylation defect at exon A/B: Evidence for a long-range regulatory element within the imprinted GNAS1 locus
    • Bastepe M, Pincus JE, Sugimoto T, Tojo K, Kanatani M, Azuma Y, Kruse K, Rosenbloom AL, Koshiyama H, Jüppner H,. Positional dissociation between the genetic mutation responsible for pseudohypoparathyroidusm type 1b and the associated methylation defect at exon A/B: evidence for a long-range regulatory element within the imprinted GNAS1 locus. Hum Mol Genet. 2001; 101231-41.
    • (2001) Hum Mol Genet. , pp. 101231-101241
    • Bastepe, M.1    Pincus, J.E.2    Sugimoto, T.3    Tojo, K.4    Kanatani, M.5    Azuma, Y.6    Kruse, K.7    Rosenbloom, A.L.8    Koshiyama, H.9    Jüppner, H.10
  • 9
    • 42449155119 scopus 로고    scopus 로고
    • The GNAS locus and pseudohypoparathyroidism
    • Bastepe M,. The GNAS locus and pseudohypoparathyroidism. Adv Exp Med Biol. 2008; 626: 27-40.
    • (2008) Adv Exp Med Biol. , vol.626 , pp. 27-40
    • Bastepe, M.1
  • 12
    • 0034740058 scopus 로고    scopus 로고
    • Gαs transcripts are biallelically expressed in the human kidney cortex: Implications for pseudohypoparathyroidism type 1b
    • DOI 10.1210/jc.86.10.4627
    • Zheng H, Radeva G, McCann JA, Hendy GN, Goodyer CG,. Gαs transcripts are biallelically expressed in human kidney cortex: implications for pseudohypoparathyroidism type 1b. J Clin Endocrinol Metab. 2001; 86: 4627-9. (Pubitemid 33020497)
    • (2001) Journal of Clinical Endocrinology and Metabolism , vol.86 , Issue.10 , pp. 4627-4629
    • Zheng, H.1    Radeva, G.2    McCann, J.A.3    Hendy, G.N.4    Goodyer, C.G.5
  • 17
    • 0034721886 scopus 로고    scopus 로고
    • Characterization of the extra-large G protein α-subunit Xlas: II. Signal transduction properties
    • Klemke M, Pasolli HA, Kehlenbach RH, Offermanns S, Schultz G, Huttner WB,. Characterization of the extra-large G protein α-subunit Xlas: II. Signal transduction properties. J Biol Chem. 2000; 275: 33633-40.
    • (2000) J Biol Chem. , vol.275 , pp. 33633-33640
    • Klemke, M.1    Pasolli, H.A.2    Kehlenbach, R.H.3    Offermanns, S.4    Schultz, G.5    Huttner, W.B.6
  • 18
    • 0036020511 scopus 로고    scopus 로고
    • Receptor-mediated adenylyl cyclase activation through XLαs, the extra-large variant of the stimulatory G protein α-subunit
    • DOI 10.1210/me.2002-0054
    • Bastepe M, Gunes Y, Perez-Villamil B, Hunzelman J, Weinstein Lee S, Jüppner H,. Receptor-mediated adenylyl cyclase activation through XLαs, the extra-large variant of the stimulatory G protein α-subunit. Mol Endocrinol. 2002; 16: 1912-9. (Pubitemid 34828097)
    • (2002) Molecular Endocrinology , vol.16 , Issue.8 , pp. 1912-1919
    • Bastepe, M.1    Gunes, Y.2    Perez-Villamil, B.3    Hunzelman, J.4    Weinstein, L.S.5    Juppner, H.6
  • 19
    • 33645888144 scopus 로고    scopus 로고
    • Coding GNAS mutations leading to hormone resistance impair in vitro agonist- and cholera toxin-induced adenosine cyclic 3',5'-monophoshate formation mediated by human XLαs
    • Linglart A, Mahon MJ, Kerachian MA, Berlach DM, Hendy GN, Jüppner H, Bastepe M,. Coding GNAS mutations leading to hormone resistance impair in vitro agonist- and cholera toxin-induced adenosine cyclic 3',5'-monophoshate formation mediated by human XLαs. Endocrinology. 2006; 147: 2253-62.
    • (2006) Endocrinology. , vol.147 , pp. 2253-2262
    • Linglart, A.1    Mahon, M.J.2    Kerachian, M.A.3    Berlach, D.M.4    Hendy, G.N.5    Jüppner, H.6    Bastepe, M.7
  • 20
    • 0030998512 scopus 로고    scopus 로고
    • Molecular cloning and characterization of NESP55, a novel chromogranin- like precursor of a peptide with 5-HT(1B) receptor antagonist activity
    • DOI 10.1074/jbc.272.17.11657
    • Ischia R, Lovisetti-Scamihorn P, Hogue-Angeletti R, Wolkersdorfer M, Winkler H, Fischer-Coldbrie R,. Molecular cloning and characterization of NESP55, a novel chromogranin-like precursor of a peptide with 5-HT1B receptor antagonist activity. J Biol Chem. 1997; 272: 11657-62. (Pubitemid 27184179)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.17 , pp. 11657-11662
    • Ischia, R.1    Lovisetti-Scamihorn, P.2    Hogue-Angeletti, R.3    Wolkersdorfer, M.4    Winkler, H.5    Fischer-Colbrie, R.6
  • 21
  • 22
    • 0025814814 scopus 로고
    • Differential expression of novel Gsα signal transduction protein cDNA species
    • Swaroop A, Agarwal N, Gruen JR, Bick D, Weissman SM,. Differential expression of novel Gαs signal transduction protein cDNA species. Nucleic Acids Res. 1991; 19: 4725-9. (Pubitemid 21912856)
    • (1991) Nucleic Acids Research , vol.19 , Issue.17 , pp. 4725-4729
    • Swaroop, A.1    Agarwal, N.2    Gruen, J.R.3    Bick, D.4    Weissman, S.M.5
  • 23
    • 80053209313 scopus 로고
    • Radiographic atlas of skeletal development of the hand and wrist, 2nd ed. Stanford, CA, USA: Stanford University Press
    • Greulich WW, Pyle SI., Radiographic atlas of skeletal development of the hand and wrist, 2nd ed. Stanford, CA, USA: Stanford University Press; 1959, 125-83.
    • (1959) , pp. 125-183
    • Greulich, W.W.1    Pyle, S.I.2
  • 24
    • 0013912696 scopus 로고
    • The roentgen appearance of pseudohypoparathyroidism (PH) and pseudo-pseudohypoparathyroidism. (PPH)
    • Steinbach HL, Young DA,. The roentgen appearance of pseudohypoparathyroidism (PH) and pseudo-pseudohypoparathyroidism. (PPH). Am J Roentgenol Radium Ther Nucl Med. 1966; 97: 49-66.
    • (1966) Am J Roentgenol Radium Ther Nucl Med. , vol.97 , pp. 49-66
    • Steinbach, H.L.1    Young, D.A.2
  • 25
    • 0027210606 scopus 로고
    • Heterogeneous mutations in the gene encoding the α-subunit of the stimulatory G protein of adenylyl cyclase in Albright hereditary osteodystrophy
    • DOI 10.1210/jc.76.6.1560
    • Miric A, Vechio JD, Levine MA,. Heterogeneous mutations in the gene encoding the α-subunit of the stimulatory G protein of adenylyl cyclase in Albright hereditary osteodystrophy. J Clin Endocrinol Metab. 1993; 76: 1560-8. (Pubitemid 23164378)
    • (1993) Journal of Clinical Endocrinology and Metabolism , vol.76 , Issue.6 , pp. 1560-1568
    • Miric, A.1    Vechio, J.D.2    Levine, M.A.3
  • 26
    • 0033855731 scopus 로고    scopus 로고
    • Activating and inactivating mutations in the human GNAS1 gene
    • Aldred MA, Trembath RC,. Activating and inactivating mutations in the human GNAS1 gene. Hum Mutat. 2000; 16: 183-9.
    • (2000) Hum Mutat. , vol.16 , pp. 183-189
    • Aldred, M.A.1    Trembath, R.C.2
  • 27
    • 0027325376 scopus 로고
    • Identical complementary deoxyribonucleic acids encode a human renal and bone parathyroid hormone (PTH)/PTH-related peptide receptor
    • DOI 10.1210/en.132.5.2157
    • Schipani E, Karga H, Karaplis AC, Potts JT Jr, Kronenberg HM, Segre GV, Abou-Samra AB, Juppner H,. Identical complementary deoxyribonucleic acids encode a human renal and bone parathyroid hormone (PTH)/PTH-related peptide receptor. Endocrinology. 1993; 132: 2157-65. (Pubitemid 23133266)
    • (1993) Endocrinology , vol.132 , Issue.5 , pp. 2157-2165
    • Schipani, E.1    Karga, H.2    Karaplis, A.C.3    Potts Jr., J.T.4    Kronenberg, H.M.5    Segre, G.V.6    Abou-Samra, A.-B.7    Juppner, H.8
  • 30
    • 0035808314 scopus 로고    scopus 로고
    • Selective resistance to parathyroid hormone caused by a novel uncoupling mutation in the carboxyl terminus of Gα(s). A cause of pseudohypoparathyroidism type 1b
    • Wu WI, Schwindinger WF, Aparicio LF, Levine MA,. Selective resistance to parathyroid hormone caused by a novel uncoupling mutation in the carboxyl terminus of Gα(s). A cause of pseudohypoparathyroidism type 1b. J Biol Chem. 2001; 276: 65-171.
    • (2001) J Biol Chem. , vol.276 , pp. 65-171
    • Wu, W.I.1    Schwindinger, W.F.2    Aparicio, L.F.3    Levine, M.A.4
  • 33
    • 84856593135 scopus 로고    scopus 로고
    • The GNAS locus: Quintessential complex gene encoding Gsα, XLαs, and other imprinted transcripts
    • Bastepe M,. The GNAS locus: quintessential complex gene encoding Gsα, XLαs, and other imprinted transcripts. Curr Genomics. 2007; 9: 171-80.
    • (2007) Curr Genomics. , vol.9 , pp. 171-180
    • Bastepe, M.1
  • 34
    • 0042165833 scopus 로고    scopus 로고
    • Discordance between genetic and epigenetic defects in pseudohypoparathyroidism type 1b revealed by inconsistent loss of maternal imprinting at GNAS1
    • DOI 10.1086/377136
    • Jan de Beur SM, Ding C, Germain-Lee E, Cho J, Maret A, Levine MA,. Discordance between genetic and epigenetic defects in pseudohypoparathyroidism type 1b revealed by inconsistent loss of maternal imprinting at GNAS1. Am J Hum Genet. 2003; 73: 314-22. (Pubitemid 36920994)
    • (2003) American Journal of Human Genetics , vol.73 , Issue.2 , pp. 314-322
    • De Beur, S.J.1    Ding, C.2    Germain-Lee, E.3    Cho, J.4    Maret, A.5    Levine, M.A.6
  • 36
    • 0035854829 scopus 로고    scopus 로고
    • Gα minigenes expressing C-terminal peptides serve as specific inhibitors of thrombin-mediated endothelial activation
    • Gilchrist A, Vanhauwe JF, Li A, Thomas TO, Voyno-Yasenetskaya T, Hamm HE,. Gα minigenes expressing C-terminal peptides serve as specific inhibitors of thrombin-mediated endothelial activation. J Biol Chem. 2001; 276: 25672-9.
    • (2001) J Biol Chem. , vol.276 , pp. 25672-25679
    • Gilchrist, A.1    Vanhauwe, J.F.2    Li, A.3    Thomas, T.O.4    Voyno-Yasenetskaya, T.5    Hamm, H.E.6
  • 37
    • 0032562289 scopus 로고    scopus 로고
    • Targeting the receptor-G(q) interface to inhibit in vivo pressure overload myocardial hypertrophy
    • DOI 10.1126/science.280.5363.574
    • Akhter SA, Luttrell LM, Rockman HA, Iaccarino G, Lefkowitz RJ, Koch WJ,. Targeting the receptor-Gq interface to inhibit in vivo pressure overload myocardial hypertrophy. Science. 1998; 280: 574-7. (Pubitemid 28227758)
    • (1998) Science , vol.280 , Issue.5363 , pp. 574-577
    • Akhter, S.A.1    Luttrell, L.M.2    Rockman, H.A.3    Iaccarino, G.4    Lefkowitz, R.J.5    Koch, W.J.6
  • 40
    • 0035040818 scopus 로고    scopus 로고
    • Regulation and role of adenylyl cyclase isoforms
    • DOI 10.1146/annurev.pharmtox.41.1.145
    • Hanoune J, Defer N,. Regulation and role of adenylyl cyclase isoforms. Annu Rev Pharmacol Toxicol. 2001; 41: 145-74. (Pubitemid 32385886)
    • (2001) Annual Review of Pharmacology and Toxicology , vol.41 , pp. 145-174
    • Hanoune, J.1    Defer, N.2
  • 41
    • 0036972975 scopus 로고    scopus 로고
    • Characterization of the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms
    • DOI 10.1081/RRS-120014589
    • Ludwig MG, Seuwen K,. Characterization the human adenylyl cyclase gene family: cDNA, gene structure, and tissue distribution of the nine isoforms. J Recept Signal Transduct Res. 2002; 22: 79-110. (Pubitemid 36169141)
    • (2002) Journal of Receptors and Signal Transduction , vol.22 , Issue.1-4 , pp. 79-110
    • Ludwig, M.-G.1    Seuwen, K.2
  • 44
    • 67651163684 scopus 로고    scopus 로고
    • Extralarge XLαs (XXLαs), a variant of stimulatory G protein α-subunit (Gsα), is a distinct, membrane-anchored GNAS product that can mimic Gsα
    • Aydin C, Aytan N, Mahon MJ, Tawfeek HA, Kowall HA, Dedeoglu A, Bastepe M,. Extralarge XLαs (XXLαs), a variant of stimulatory G protein α-subunit (Gsα), is a distinct, membrane-anchored GNAS product that can mimic Gsα. Endocrinology. 2009; 150: 3567-75.
    • (2009) Endocrinology. , vol.150 , pp. 3567-3575
    • Aydin, C.1    Aytan, N.2    Mahon, M.J.3    Tawfeek, H.A.4    Kowall, H.A.5    Dedeoglu, A.6    Bastepe, M.7
  • 45
    • 3543036987 scopus 로고    scopus 로고
    • The imprinted signaling protein XLαs is required for postnatal adaptation to feeding
    • DOI 10.1038/ng1397
    • Plagge A, Gordon E, Dean W, Boiani R, Cinti S, Peters J, Kelsey G,. The imprinted signalling protein XLαs is required for postnatal adaptation to feeding. Nat Genet. 2004; 36: 818-26. (Pubitemid 39014098)
    • (2004) Nature Genetics , vol.36 , Issue.8 , pp. 818-826
    • Plagge, A.1    Gordon, E.2    Dean, W.3    Boiani, R.4    Cinti, S.5    Peters, J.6    Kelsey, G.7
  • 46
    • 33745806530 scopus 로고    scopus 로고
    • The alternative stimulatory G protein α-subunit XLαs is a critical regulator of energy and glucose metabolism and sympathetic nerve activity in adult mice
    • DOI 10.1074/jbc.M511752200
    • Xie T, Plagge A, Gavrilova O, Pack S, Jou W, Lai EW, Fronetra M, Kelsey G, Weinstein LS,. The alternative stimulatory G protein α-subunit is a critical regulator of energy and glucose metabolism and sympathetic nerve activity in adult mice. J Biol Chem. 2006; 281: 18989-99. (Pubitemid 44035402)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.28 , pp. 18989-18999
    • Xie, T.1    Plagge, A.2    Gavrilova, O.3    Pack, S.4    Jou, W.5    Lai, E.W.6    Frontera, M.7    Kelsey, G.8    Weinstein, L.S.9


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