Myosin phosphatase target subunit: Many roles in cell function

Biochemical and Biophysical Research Communications

Volumn 369, Issue 1, 2008, Pages 149-156

  Matsumura, Fumio ^a   Hartshorne, David J ^b  

^a RUTGERS UNIVERSITY   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

Author keywords

Cell division; Cell migration; Myosin II phosphorylation; Myosin phosphatase; Myosin phosphatase targeting subunit

Indexed keywords

MYOSIN II; MYOSIN LIGHT CHAIN KINASE; MYOSIN PHOSPHATASE TARGET SUBUNIT; PHOSPHATASE; UNCLASSIFIED DRUG;

ARTICLE; CELL DIVISION; CELL MIGRATION; CELLULAR DISTRIBUTION; ENZYME ACTIVITY; ENZYME SUBUNIT; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION;

CELL DIVISION; CELL MOVEMENT; ENZYME ACTIVATION; MODELS, BIOLOGICAL; MYOSIN TYPE II; MYOSIN-LIGHT-CHAIN PHOSPHATASE; PHOSPHORYLATION;

EID: 40849097955     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.12.090     Document Type: Article

References (66)

1. Hartshorne D.J., Ito M., and Erdodi F. Role of protein phosphatase type 1 in contractile functions: myosin phosphatase. J. Biol. Chem. 279 (2004) 37211-37214
2. Dirksen W.P., Vladic F., and Fisher S.A. A myosin phosphatase targeting subunit isoform transition defines a smooth muscle developmental phenotypic switch. Am. J. Physiol. Cell Physiol. 278 (2000) C589-C600
3. Payne M.C., Zhang H.-Y., Prosdocimo T., Joyce K.M., Koga Y., Ikebe M., and Fisher S.A. Myosin phosphatase isoform switching in vascular smooth muscle development. J. Mol. Cell. Cardiol. 40 (2006) 274-282
4. Wu Y., Muranyi A., Erdodi F., and Hartshorne D.J. Localization of myosin phosphatase target subunit and its mutants. J. Mus. Res. Cell Motil. 26 (2005) 123-134
5. Toth A., Kiss E., Herberg F.W., Hartshorne D.J., and Erdodi F. Study of the subunit interactions in myosin phosphatase by surface plasmon resonance. Eur. J. Biochem. 267 (2000) 1687-1697
6. Hirano K., Phan B.C., and Hartshorne D.J. Interactions of the subunits of smooth muscle myosin phosphatase. J. Biol. Chem. 272 (1997) 3683-3688
7. Terrak M., Kerff F., Langsetmo K., Tao T., and Dominguez R. Structural basis of protein phosphatase 1 regulation. Nature 429 (2004) 780-784
8. Velasco G., Armstrong C., Morrice N., Frame S., and Cohen P. Phosphorylation of the regulatory subunit of smooth muscle protein phosphatase 1 M at Thr850 induces its dissociation from myosin. FEBS Lett. 527 (2002) 101-104
9. Surks H.K., Riddick N., and Ohtani K.-I. M-RIP targets myosin phosphatase to stress fibers to regulate myosin light chain phosphorylation in vascular smooth muscle cells. J.Biol.Chem. 280 (2005) 42543-42551
10. Haystead T.A.J. ZIP kinase, a key regulator of myosin protein phosphatase 1. Cell. Signal. 17 (2005) 1313-1322
11. Rip is a novel filamentous actin-binding protein. J. Biol. Chem. 278 (2003) 27216-27223
12. Rip. FEBS. Lett. 579 (2005) 6121-6127
13. Rip decreases myosin II phosphorylation by activating myosin light chain phosphatase and by inactivating RhoA. J. Biol. Chem. 280 (2005) 4983-4991
14. Jin H., Sperka T., Herrlich P., and Morrison H. Tumorigenic transformation by CPI-17 through inhibition of merlin phosphatase. Nature 442/3 (2006) 576-579
15. Parra M., Mahmoudi T., and Verdin E. Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes. Genes Dev. 21 (2007) 638-643
16. Patil S.B., and Bitar K.N. RhoA- and PKC-α-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells. Am. J. Physiol. Gastrointest. Liver Physiol. 290 (2005) G83-G95
17. Lontay B., Serfozo Z., Gergely P., Ito M., Hartshorne D.J., and Erdodi F. Localization of myosin phosphatase target subunit 1 in rat brain and in primary cultures of neuronal cells. J. Comp. Neurol. 478 (2004) 72-87
18. Lontay B., Kiss A., Gergely P., Hartshorne D.J., and Erdodi F. Okadaic acid induces phosphorylation and translocation of myosin phosphatase target subunit 1 influencing myosin phosphorylation, stress fiber assembly and cell migration in HepG2 cells. Cell. Signal. 17 (2005) 1265-1275
19. Tran H.T., Ulke A., Morrice N., Johannes C.J., and Moorhead G.B.G. Proteomic characterization of protein phosphatase complexes of the mammalian nucleus. Mol. Cell. Proteom. 3 (2004) 257-265
20. Murata K., Hirano K., Villa-Moruzzi E., Hartshorne D.J., and Brautigan D.L. Differential localization of myosin and myosin phosphatase subunits in smooth muscle cells and migrating fibroblasts. Mol. Biol. Cell 8 (1997) 663-673
21. Inagaki N., Nishizawa M., Ito M., Fujioka M., Nakano T., Tsujino S., Matsuzawa K., Kimura K., Kaibuchi K., and Inagaki M. Myosin binding subunit of smooth muscle myosin phosphatase at the cell-cell adhesion sites in MDCK cells. Biochem. Biophys. Res. Commun. 230 (1997) 552-556
22. Fukata Y., Kimura K., Oshiro N., Saya H., Matsuura Y., and Kaibuchi K. Association of the myosin-binding subunit of myosin phosphatase and moesin: dual regulation of moesin phosphorylation by Rho-associated kinase and myosin phosphatase. J. Cell Biol. 141 (1998) 409-418
23. Shin H.-M., Je H.-D., Gallant C., Tao T.C., Hartshorne D.J., Ito M., and Morgan K.G. Differential association and localization of myosin phosphatase subunits during agonist-induced signal transduction in smooth muscle. Circ. Res. 90 (2002) 546-553
24. Kawano Y., Fukata Y., Oshiro N., Amano M., Nakamura T., Ito M., Matsumura F., Inagaki M., and Kaibuchi K. Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by Rho-kinase in vivo. J. Cell Biol. 147 (1999) 1023-1037
25. Mabuchi I., and Okuno M. The effect of myosin antibody on the division of starfish blastomeres. J. Cell Biol. 74 (1977) 251-263
26. DeLozanne A., and Spudich J.A. Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination. Science 236 (1987) 1086-1091
27. Matsumura F., Ono S., Yamakita Y., Totsukawa G., and Yamashiro S. Specific localization of serine 19 phosphorylated myosin II during cell locomotion and mitosis of cultured cells. J. Cell Biol. 140 (1998) 119-129
28. Yokoyama T., Goto H., Izawa I., Mizutani H., and Inagaki M. Aurora-B and Rho-kinase/ROCK, the two cleavage furrow kinases, independently regulate the progression of cytokinesis: possible existence of a novel cleavage furrow kinase phosphorylates ezrin/radixin/moesin (ERM). Genes Cells 10 (2005) 127-137
29. Poperechnaya A., Varlamova O., Lin P.J., Stull J.T., and Bresnick A.R. Localization and activity of myosin light chain kinase isoforms during the cell cycle. J. Cell Biol. 151 (2000) 697-708
30. Chew T.L., Wolf W.A., Gallagher P.J., Matsumura F., and Chisholm R.L. A fluorescent resonant energy transfer-based biosensor reveals transient and regional myosin light chain kinase activation in lamella and cleavage furrows. J. Cell Biol. 156 (2002) 543-553
31. Kosako H., Goto H., Yanagida M., Matsuzawa K., Fujita M., Tomono Y., Okigaki T., Odai H., Kaibuchi K., and Inagaki M. Specific accumulation of Rho-associated kinase at the cleavage furrow during cytokinesis: cleavage furrow-specific phosphorylation of intermediate filaments. Oncogene 18 (1999) 2783-2788
32. Madaule P., Eda M., Watanabe N., Fujisawa K., Matsuoka T., Bito H., Ishizaki T., and Narumiya S. Role of citron kinase as a target of the small GTPase Rho in cytokinesis. Nature 394 (1998) 491-494
33. Yamashiro S., Totsukawa G., Yamakita Y., Sasaki Y., Madaule P., Ishizaki T., Narumiya S., and Matsumura F. Citron kinase, a Rho-dependent kinase, induces di-phosphorylation of regulatory light chain of myosin II. Mol. Biol. Cell 14 (2003) 1745-1756
34. Schroeder T.E. In: Goldman R., Pollard T., and Rosenbaum J. (Eds). Cell Motility (1976), Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 265-278
35. Rappaport R. Cytokinesis in Animal Cells. first ed. (1996), Cambridge University Press, Cambridge
36. Scholey J.M., Taylor K.A., and Kendrick-Jones J. Regulation of non-muscle myosin assembly by calmodulin-dependent light chain kinase. Nature 287 (1980) 233-235
37. Kishi K., Sasaki T., Kuroda S., Itoh T., and Takai Y. Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI). J. Cell Biol. 120 (1993) 1187-1195
38. Mabuchi I., Hamaguchi Y., Fujimoto H., Morii N., Mishima M., and Narumiya S. A rho-like protein is involved in the organisation of the contractile ring in dividing sand dollar eggs. Zygote 1 (1993) 325-331
39. Drechsel D.N., Hyman A.A., Hall A., and Glotzer M. A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos. Curr. Biol. 7 (1997) 12-23
40. Petronczki M., Glotzer M., Kraut N., and Peters J.M. Polo-like kinase 1 triggers the initiation of cytokinesis in human cells by promoting recruitment of the RhoGEF Ect2 to the central spindle. Dev. Cell 12 (2007) 713-725
41. Burkard M.E., Randall C.L., Larochelle S., Zhang C., Shokat K.M., Fisher R.P., and Jallepalli P.V. Chemical genetics reveals the requirement for Polo-like kinase 1 activity in positioning RhoA and triggering cytokinesis in human cells. Proc. Natl. Acad. Sci. USA 104 (2007) 4383-4388
42. Balasubramanian M.K., Bi E., and Glotzer M. Comparative analysis of cytokinesis in budding yeast, fission yeast and animal cells. Curr. Biol. 14 (2004) R806-R818
43. Glotzer M. Cleavage furrow positioning. J. Cell Biol. 164 (2004) 347-351
44. Barr F.A., Sillje H.H., and Nigg E.A. Polo-like kinases and the orchestration of cell division. Nat. Rev. Mol. Cell. Biol. 5 (2004) 429-440
45. Birkenfeld J., Nalbant P., Bohl B.P., Pertz O., Hahn K.M., and Bokoch G.M. GEF-H1 modulates localized RhoA activation during cytokinesis under the control of mitotic kinases. Dev. Cell 12 (2007) 699-712
46. Wu D., Asiedu M., Adelstein R.S., and Wei Q. A novel guanine nucleotide exchange factor MyoGEF is required for cytokinesis. Cell Cycle 5 (2006) 1234-1239
47. Totsukawa G., Yamakita Y., Yamashiro S., Hosoya H., Hartshorne D.J., and Matsumura F. Activation of myosin phosphatase targeting subunit by mitosis-specific phosphorylation. J. Cell Biol. 144 (1999) 735-744
48. Lauffenburger D.A., and Horwitz A.F. Cell migration: a physically integrated molecular process. Cell 84 (1996) 359-369
49. Mitchison T.J., and Cramer L.P. Actin-based cell motility and cell locomotion. Cell 84 (1996) 371-379
50. Ridley A.J. Rho GTPases and cell migration. J. Cell Sci. 114 (2001) 2713-2722
51. Pollard T.D., Blanchoin L., and Mullins R.D. Molecular mechanisms controlling actin filament dynamics in nonmuscle cells. Annu. Rev. Biophys. Biomol. Struct. 29 (2000) 545-576
52. Nobes C.D., and Hall A. Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81 (1995) 53-62
53. Post P.L., DeBiasio R.L., and Taylor D.L. A fluorescent protein biosensor of myosin II regulatory light chain phosphorylation reports a gradient of phosphorylated myosin II in migrating cells. Mol. Biol. Cell 6 (1995) 1755-1768
54. Totsukawa G., Wu Y., Sasaki Y., Hartshorne D.J., Yamakita Y., Yamashiro S., and Matsumura F. Distinct roles of MLCK and ROCK in the regulation of membrane protrusions and focal adhesion dynamics during cell migration of fibroblasts. J. Cell Biol. 164 (2004) 427-439
55. Cai Y., Biais N., Giannone G., Tanase M., Jiang G., Hofman J.M., Wiggins C.H., Silberzan P., Buguin A., Ladoux B., and Sheetz M.P. Nonmuscle myosin IIA-dependent force inhibits cell spreading and drives F-actin flow. Biophys. J. 91 (2006) 3907-3920
56. Chrzanowska-Wodnicka M., and Burridge K. Rho-stimulated contractility drives the formation of stress fibers and focal adhesions. J. Cell Biol. 133 (1996) 1403-1415
57. Xia D., Stull J.T., and Kamm K.E. Myosin phosphatase targeting subunit 1 affects cell migration by regulating myosin phosphorylation and actin assembly. Exp. Cell Res. 304 (2005) 506-517
58. Wu Y., Erdodi F., Muranyi A., Nullmeyer K.D., Lynch R.M., and Hartshorne D.J. Myosin phosphatase and myosin phosphorylation in differentiating C2C12 cells. J. Muscle Res. Cell Motil. 24 (2003) 499-511
59. Uehata M., Ishizaki T., Satoh H., Ono T., Kawahara T., Morishita T., Tamakawa H., Yamagami K., Inui J., Maekawa M., and Narumiya S. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Nature 389 (1997) 990-994
60. Giannone G., Dubin-Thaler B.J., Dobereiner H.G., Kieffer N., Bresnick A.R., and Sheetz M.P. Periodic lamellipodial contractions correlate with rearward actin waves. Cell 116 (2004) 431-443
61. Webb D.J., Donais K., Whitmore L.A., Thomas S.M., Turner C.E., Parsons J.T., and Horwitz A.F. FAK-Src signalling through paxillin, ERK and MLCK regulates adhesion disassembly. Nat. Cell Biol. 6 (2004) 154-161
62. Mizuno T., Tsutsui K., and Nishida Y. Drosophila myosin phosphatase and its role in dorsal closure. Development 129 (2002) 1215-1223
63. Tan C., Stronach B., and Perrimon N. Roles of myosin phosphatase during Drosophila development. Development 130 (2003) 671-681
64. Wissmann A., Ingles J., McGhee J.D., and Mains P.E. Caenorhabditis elegans LET-502 is related to Rho-binding kinases and human myotonic dystrophy kinase and interacts genetically with a homolog of the regulatory subunit of smooth muscle myosin phosphatase to affect cell shape. Genes Dev. 11 (1997) 409-422
65. Piekny A.J., and Mains P.E. Rho-binding kinase (LET-502) and myosin phosphatase (MEL-11) regulate cytokinesis in the early Caenorhabditis elegans embryo. J. Cell Sci. 115 (2002) 2271-2282
66. Okamoto R., Ito M., Suzuki N., Kongo M., Moriki N., Saito H., Tsumura H., Imanaka-Yoshida K., Kimura K., Mizoguchi A., Hartshorne D.J., and Nakano T. The targeted disruption of the MYPT1 gene results in embryonic lethality. Transgenic Res. 14 (2005) 337-340