SH2-domain mutations in STAT3 in hyper-IgE syndrome patients result in impairment of IL-10 function

European Journal of Immunology

Volumn 41, Issue 10, 2011, Pages 3075-3084

  Giacomelli, Mauro ^a,b   Tamassia, Nicola ^c   Moratto, Daniele ^a   Bertolini, Patrizia ^d   Ricci, Giampaolo ^e   Bertulli, Cristina ^a   Plebani, Alessandro ^a   Cassatella, Marco ^c   Bazzoni, Flavia ^c   Badolato, Raffaele ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

^c UNIVERSITY OF VERONA   (Italy)

^d UNIVERSITY OF PARMA   (Italy)

^e UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

DCs; IL 1 receptor antagonist; IL 10; Monocytes; Neutrophils

Indexed keywords

CD14 ANTIGEN; CD83 ANTIGEN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; MESSENGER RNA; PROTEIN SH2; STAT1 PROTEIN; STAT3 PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ABSCESS; ADOLESCENT; ADULT; ARTICLE; AUTOSOMAL DOMINANT DISORDER; BONE MARROW CELL; CELL ISOLATION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CXCL8 GENE; CYTOKINE RELEASE; DENDRITIC CELL; ECZEMA; FEMALE; GENE; GENE EXPRESSION; GENE MUTATION; HEALING; HUMAN; HUMAN CELL; HYPER IGE SYNDROME; IL1RN GENE; IMMUNE DEFICIENCY; IMMUNOREGULATION; INFLAMMATION; LUNG INFECTION; MALE; MONOCYTE; NEUTROPHIL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RECURRENT INFECTION; SIGNAL TRANSDUCTION; SOCS3 GENE; STAPHYLOCOCCUS; STAT3 GENE;

ADOLESCENT; ADULT; BASE SEQUENCE; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; DENDRITIC CELLS; FEMALE; GENE EXPRESSION PROFILING; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-10; INTERLEUKIN-12; INTERLEUKIN-6; INTERLEUKIN-8; JOB'S SYNDROME; LIPOPOLYSACCHARIDES; MALE; MONOCYTES; MYELOID CELLS; NEUTROPHILS; PHOSPHORYLATION; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 80053158135     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201141721     Document Type: Article

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