Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity

Journal of Pharmacology and Experimental Therapeutics

Volumn 339, Issue 1, 2011, Pages 115-124

  Longo, Kenneth A ^a   Govek, Elizabeth K ^a   Nolan, Anna ^a   McDonagh, Thomas ^a   Charoenthongtrakul, Soratree ^a   Giuliana, Derek J ^a   Morgan, Kristen ^a   Hixon, Jeffrey ^a   Zhou, Chaoseng ^a   Kelder, Bruce ^b   Kopchick, John J ^b   Saunders, Jeffrey O ^a   Navia, Manuel A ^a   Curtis, Rory ^a   DiStefano, Peter S ^a   Geddes, Brad J ^a  

^a Elixir Pharmaceuticals Inc   (United States)

^b OHIO UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GHRELIN RECEPTOR; GHRELIN RECEPTOR ANTAGONIST; RECEPTOR BLOCKING AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG RESPONSE; DRUG SAFETY; FATTY LIVER; FOOD INTAKE; GENE SILENCING; GLUCOSE TOLERANCE; INSULIN RELEASE; INSULIN SENSITIVITY; LIVER FUNCTION; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SINGLE DRUG DOSE; WEIGHT REDUCTION; WHITE ADIPOSE TISSUE; WILD TYPE;

ANIMALS; ANTI-OBESITY AGENTS; BLOOD GLUCOSE; BODY WEIGHT; CHO CELLS; CRICETINAE; CRICETULUS; DIETARY FATS; EATING; GHRELIN; GLUCOSE CLAMP TECHNIQUE; IMMUNOHISTOCHEMISTRY; INSULIN; INSULIN RESISTANCE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; OBESITY; RECEPTORS, GHRELIN; SIGNAL TRANSDUCTION; STRESS, PHYSIOLOGICAL;

EID: 80053156695     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.183764     Document Type: Article

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