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Volumn 152, Issue 10, 2011, Pages 3905-3916

Unsaturated fatty acids stimulate LH secretion via novel PKCε and -θ in gonadotrope cells and inhibit GnRH-induced LH release

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOTROPIN; GONADORELIN; LINOLEIC ACID; LUTEINIZING HORMONE BETA SUBUNIT; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OLEIC ACID; PALMITIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PROTEIN KINASE C EPSILON; PROTEIN KINASE C THETA; THYROTROPIN; UNSATURATED FATTY ACID;

EID: 80053155457     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2011-1167     Document Type: Article
Times cited : (36)

References (56)
  • 2
    • 0033025052 scopus 로고    scopus 로고
    • Modulation of gonadotropin levels by peptides acting at the anterior pituitary gland
    • DOI 10.1210/er.20.1.46
    • Evans JJ 1999 Modulation of gonadotropin levels by peptides acting at the anterior pituitary gland. Endocr Rev 20:46-67 (Pubitemid 29091459)
    • (1999) Endocrine Reviews , vol.20 , Issue.1 , pp. 46-67
    • Evans, J.J.1
  • 3
    • 58049165874 scopus 로고    scopus 로고
    • Signaling by G-protein-coupled receptor (GPCR): Studies on the GnRH receptor
    • Naor Z 2009 Signaling by G-protein-coupled receptor (GPCR): studies on the GnRH receptor. Front Neuroendocrinol 30:10-29
    • (2009) Front Neuroendocrinol , vol.30 , pp. 10-29
    • Naor, Z.1
  • 4
    • 75949117797 scopus 로고    scopus 로고
    • The GnRH receptor and the response of gonadotrope cells to GnRH pulse frequency code. A story of an atypical adaptation of cell function relying on a lack of receptor homologous desensitization
    • Counis R, Garrel G, Laverriere JN, Simon V, Bleux C, Magre S, Cohen-Tannoudji J 2009 The GnRH receptor and the response of gonadotrope cells to GnRH pulse frequency code. A story of an atypical adaptation of cell function relying on a lack of receptor homologous desensitization. Folia Histochem Cytobiol 47:S81-S87
    • (2009) Folia Histochem Cytobiol , vol.47
    • Counis, R.1    Garrel, G.2    Laverriere, J.N.3    Simon, V.4    Bleux, C.5    Magre, S.6    Cohen-Tannoudji, J.7
  • 5
    • 0031765845 scopus 로고    scopus 로고
    • Evidence that gonadotropin-releasing hormone stimulates gene expression and levels of active nitric oxide synthase type I in pituitary gonadotrophs, a process altered by desensitization and, indirectly, by gonadal steroids
    • Garrel G, Lerrant Y, Siriostis C, Bérault A, Magre S, Bouchaud C, Counis R 1998 Evidence that gonadotropin-releasing hormone stimulates gene expression and levels of active nitric oxide synthase type I in pituitary gonadotrophs, a process altered by desensitization and, indirectly, by gonadal steroids. Endocrinology 139:2163-2170 (Pubitemid 28513881)
    • (1998) Endocrinology , vol.139 , Issue.4 , pp. 2163-2170
    • Garrel, G.1    Lerrant, Y.2    Siriostis, C.3    Berault, A.4    Magre, S.5    Bouchaud, C.6    Counis, R.7
  • 6
    • 33847084653 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone couples to 3′,5′-cyclic adenosine-5′-monophosphate pathway through novel protein kinase Cδ and -ε in LßT2 gonadotrope cells
    • Larivière S, Garrel G, Simon V, Soh JW, Laverrière JN, Counis R,Cohen-Tannoudji J 2007 Gonadotropin-releasing hormone couples to 3′,5′-cyclic adenosine-5′-monophosphate pathway through novel protein kinase Cδ and -ε in LßT2 gonadotrope cells. Endocrinology 148:1099-1107
    • (2007) Endocrinology , vol.148 , pp. 1099-1107
    • Larivière, S.1    Garrel, G.2    Simon, V.3    Soh, J.W.4    Laverrière, J.N.5    Counis, R.6    Cohen-Tannoudji, J.7
  • 7
    • 71849088360 scopus 로고    scopus 로고
    • Hormones in synergy: Regulation of the pituitary gonadotropin genes
    • Thackray VG, Mellon PL, Coss D 2010 Hormones in synergy: regulation of the pituitary gonadotropin genes. Mol Cell Endocrinol 314:192-203
    • (2010) Mol Cell Endocrinol , vol.314 , pp. 192-203
    • Thackray, V.G.1    Mellon, P.L.2    Coss, D.3
  • 8
    • 37049011455 scopus 로고    scopus 로고
    • Paracrinicity: The story of 30 years of cellular pituitary crosstalk
    • DOI 10.1111/j.1365-2826.2007.01616.x
    • Denef C 2008 Paracrinicity: the story of 30 years of cellular pituitary crosstalk. J Neuroendocrinol 20:1-70 (Pubitemid 350244410)
    • (2008) Journal of Neuroendocrinology , vol.20 , Issue.1 , pp. 1-70
    • Denef, C.1
  • 9
    • 57349116794 scopus 로고    scopus 로고
    • Gonadotropin-releasing hormone inhibits pituitary adenylyl cyclase-activating polypeptide coupling to 3′,5′-cyclic adenosine-5′-monophosphate pathway in LßT2 gonadotrope cells through novel protein kinase C isoforms and phosphorylation of pituitary adenylyl cyclase-activating polypeptide type I receptor
    • Larivière S, Garrel-Lazayres G, Simon V, Shintani N, Baba A, Counis R, Cohen-Tannoudji J 2008 Gonadotropin-releasing hormone inhibits pituitary adenylyl cyclase-activating polypeptide coupling to 3′,5′-cyclic adenosine-5′-monophosphate pathway in LßT2 gonadotrope cells through novel protein kinase C isoforms and phosphorylation of pituitary adenylyl cyclase-activating polypeptide type I receptor. Endocrinology 149:6389-6398
    • (2008) Endocrinology , vol.149 , pp. 6389-6398
    • Larivière, S.1    Garrel-Lazayres, G.2    Simon, V.3    Shintani, N.4    Baba, A.5    Counis, R.6    Cohen-Tannoudji, J.7
  • 10
    • 33645837036 scopus 로고    scopus 로고
    • Nutrition and reproduction in women
    • The ESHRE Capri Workshop Group
    • The ESHRE Capri Workshop Group 2006 Nutrition and reproduction in women. Hum Reprod Update 12:193-207
    • (2006) Hum Reprod Update , vol.12 , pp. 193-207
  • 12
    • 33748250844 scopus 로고    scopus 로고
    • Dynamic and integrative aspects of the regulation of reproduction by metabolic status in male sheep
    • DOI 10.1051/rnd:2006019
    • Blache D, Zhang S, Martin GB 2006 Dynamic and integrative aspects of the regulation of reproduction by metabolic status in male sheep. Reprod Nutr Dev 46:379-390 (Pubitemid 44320281)
    • (2006) Reproduction Nutrition Development , vol.46 , Issue.4 , pp. 379-390
    • Blache, D.1    Zhang, S.2    Martin, G.B.3
  • 15
    • 40849092830 scopus 로고    scopus 로고
    • Adiponectin activates adenosine monophosphate-activated protein kinase and decreases luteinizing hormone secretion in LßT2 gonadotropes
    • DOI 10.1210/me.2007-0330
    • Lu M, Tang Q, Olefsky JM, Mellon PL, Webster NJ 2008 Adiponectin activates adenosine monophosphate-activated protein kinase and decreases luteinizing hormone secretion in LßT2 gonadotropes. Mol Endocrinol 22:760-771 (Pubitemid 351397801)
    • (2008) Molecular Endocrinology , vol.22 , Issue.3 , pp. 760-771
    • Lu, M.1    Tang, Q.2    Olefsky, J.M.3    Mellon, P.L.4    Webster, N.J.G.5
  • 18
    • 0028127104 scopus 로고
    • Insulin insulin-like growth factor I (IGF-I) and IGF-II enhance basal and gonadotrophin-releasing hormone-stimulated luteinizing hormone release from rat anterior pituitary cells in vitro
    • Soldani R, Cagnacci A, Yen SS 1994 Insulin, insulin-like growth factor I (IGF-I) and IGF-II enhance basal and gonadotrophin-releasing hormone-stimulated luteinizing hormone release from rat anterior pituitary cells in vitro. Eur J Endocrinol 131:641-645 (Pubitemid 24377196)
    • (1994) European Journal of Endocrinology , vol.131 , Issue.6 , pp. 641-645
    • Soldani, R.1    Cagnacci, A.2    Yen, S.S.C.3
  • 20
    • 0019443286 scopus 로고
    • Insulin enhancement of luteinizing hormone and follicle-stimulating hormone release by cultured pituitary cells
    • Adashi EY, Hsueh AJ, Yen SS 1981 Insulin enhancement of luteinizing hormone and follicle-stimulating hormone release by cultured pituitary cells. Endocrinology 108:1441-1449 (Pubitemid 11079170)
    • (1981) Endocrinology , vol.108 , Issue.4 , pp. 1441-1449
    • Adashi, E.Y.1    Hsueh, A.J.W.2    Yen, S.S.C.3
  • 22
    • 0034527528 scopus 로고    scopus 로고
    • Central, but not peripheral, glucose-sensing mechanisms mediate glucoprivic suppression of pulsatile luteinizing hormone secretion in the sheep
    • DOI 10.1210/en.141.12.4472
    • Ohkura S, Tanaka T, Nagatani S, Bucholtz DC, Tsukamura H, Maeda K, Foster DL 2000 Central, but not peripheral, glucose-sensing mechanisms mediate glucoprivic suppression of pulsatile luteinizing hormone secretion in the sheep. Endocrinology 141:4472-4480 (Pubitemid 32055123)
    • (2000) Endocrinology , vol.141 , Issue.12 , pp. 4472-4480
    • Ohkura, S.1    Tanaka, T.2    Nagatani, S.3    Bucholtz, D.C.4    Tsukamura, H.5    Maeda, K.-I.6    Foster, D.L.7
  • 23
    • 34249804134 scopus 로고    scopus 로고
    • Fatty acid sensing and nervous control of energy homeostasis
    • DOI 10.1016/j.diabet.2007.01.006, PII S1262363607000638
    • Migrenne S, Magnan C, Cruciani-Guglielmacci C 2007 Fatty acid sensing and nervous control of energy homeostasis. Diabetes Metab 33:177-182 (Pubitemid 46856252)
    • (2007) Diabetes and Metabolism , vol.33 , Issue.3 , pp. 177-182
    • Migrenne, S.1    Magnan, C.2    Cruciani-Guglielmacci, C.3
  • 25
    • 0036065628 scopus 로고    scopus 로고
    • Central administration of oleic acid inhibits glucose production and food intake
    • Obici S, Feng Z, Morgan K, Stein D, Karkanias G, Rossetti L 2002 Central administration of oleic acid inhibits glucose production and food intake. Diabetes 51:271-275 (Pubitemid 34764780)
    • (2002) Diabetes , vol.51 , Issue.2 , pp. 271-275
    • Obici, S.1    Feng, Z.2    Morgan, K.3    Stein, D.4    Karkanias, G.5    Rossetti, L.6
  • 26
    • 34547445669 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids in male and female reproduction
    • DOI 10.1095/biolreprod.107.060558
    • Wathes DC, Abayasekara DR, Aitken RJ 2007 Polyunsaturated fatty acids in male and female reproduction. Biol Reprod 77:190-201 (Pubitemid 47173600)
    • (2007) Biology of Reproduction , vol.77 , Issue.2 , pp. 190-201
    • Wathes, D.C.1    Abayasekara, D.R.E.2    Aitken, R.J.3
  • 27
    • 0034613316 scopus 로고    scopus 로고
    • Fatty acid regulation of gene transcription
    • Duplus E, Glorian M, Forest C 2000 Fatty acid regulation of gene transcription. J Biol Chem 275:30749-30752
    • (2000) J Biol Chem , vol.275 , pp. 30749-30752
    • Duplus, E.1    Glorian, M.2    Forest, C.3
  • 29
    • 47749128507 scopus 로고    scopus 로고
    • Seven transmembrane- Spanning receptors for free fatty acids as therapeutic targets for diabetes mellitus: Pharmacological, phylogenetic, and drug discovery aspects
    • Costanzi S, Neumann S, Gershengorn MC 2008 Seven transmembrane- spanning receptors for free fatty acids as therapeutic targets for diabetes mellitus: pharmacological, phylogenetic, and drug discovery aspects. J Biol Chem 283:16269-16273
    • (2008) J Biol Chem , vol.283 , pp. 16269-16273
    • Costanzi, S.1    Neumann, S.2    Gershengorn, M.C.3
  • 30
    • 32544432975 scopus 로고    scopus 로고
    • Involvement of novel PKC isoforms in FFA induced defects in insulin signaling
    • DOI 10.1016/j.mce.2005.12.014, PII S0303720705004600
    • Dey D, Basu D, Roy SS, Bandyopadhyay A, Bhattacharya S 2006 Involvement of novel PKC isoforms in FFA induced defects in insulin signaling. Mol Cell Endocrinol 246:60-64 (Pubitemid 43238397)
    • (2006) Molecular and Cellular Endocrinology , vol.246 , Issue.1-2 , pp. 60-64
    • Dey, D.1    Basu, D.2    Roy, S.S.3    Bandyopadhyay, A.4    Bhattacharya, S.5
  • 31
    • 0030897513 scopus 로고    scopus 로고
    • Role of long-chain fatty acyl-CoA esters in the regulation of metabolism and in cell signalling
    • Faergeman NJ, Knudsen J 1997 Role of long-chain fatty acyl-CoA esters in the regulation of metabolism and in cell signalling. Biochem J 323:1-12 (Pubitemid 27153867)
    • (1997) Biochemical Journal , vol.323 , Issue.1 , pp. 1-12
    • Faergeman, N.J.1    Knudsen, J.2
  • 32
    • 0037312819 scopus 로고    scopus 로고
    • Leptin receptor - Deficient obese zucker rats reduce their food intake in response to a systemic supply of calories from glucose
    • DOI 10.2337/diabetes.52.2.277
    • Gilbert M, Magnan C, Turban S, André J, Guerre-Millo M 2003 Leptin receptor-deficient obese Zucker rats reduce their food intake in response to a systemic supply of calories from glucose. Diabetes 52:277-282 (Pubitemid 36173179)
    • (2003) Diabetes , vol.52 , Issue.2 , pp. 277-282
    • Gilbert, M.1    Magnan, C.2    Turban, S.3    Andre, J.4    Guerre-Millo, M.5
  • 33
    • 0029880964 scopus 로고    scopus 로고
    • Steroid and pulsatile gonadotropin-releasing hormone (GnRH) regulation of luteinizing hormone and GnRH receptor in a novel gonadotrope cell line
    • DOI 10.1210/me.10.4.439
    • Turgeon JL, Kimura Y, Waring DW, Mellon PL 1996 Steroid and pulsatile gonadotropin-releasing hormone (GnRH) regulation of luteinizing hormone and GnRH receptor in a novel gonadotrope cell line. Mol Endocrinol 10:439-450 (Pubitemid 26112407)
    • (1996) Molecular Endocrinology , vol.10 , Issue.4 , pp. 439-450
    • Turgeon, J.L.1    Kimura, Y.2    Waring, D.W.3    Mellon, P.L.4
  • 34
    • 0029894817 scopus 로고    scopus 로고
    • The LβT2 clonal gonadotrope: A model for single cell studies of endocrine cell secretion
    • DOI 10.1210/en.137.7.2979
    • Thomas P, Mellon PL, Turgeon J, Waring DW 1996 The L β T2 clonal gonadotrope: a model for single cell studies of endocrine cell secretion. Endocrinology 137:2979-2989 (Pubitemid 26192195)
    • (1996) Endocrinology , vol.137 , Issue.7 , pp. 2979-2989
    • Thomas, P.1    Mellon, P.L.2    Turgeon, J.L.3    Waring, D.W.4
  • 35
    • 77953868109 scopus 로고    scopus 로고
    • Sustained gonadotropin-releasing hormone stimulation mobilizes the cAMP/PKA pathway to induce nitric oxide synthase type 1 expression in rat pituitary cells in vitro and in vivo at proestrus
    • Garrel G, Simon V, Thieulant ML, Cayla X, Garcia A, Counis R, Cohen-Tannoudji J 2010 Sustained gonadotropin-releasing hormone stimulation mobilizes the cAMP/PKA pathway to induce nitric oxide synthase type 1 expression in rat pituitary cells in vitro and in vivo at proestrus. Biol Reprod 82:1170-1179
    • (2010) Biol Reprod , vol.82 , pp. 1170-1179
    • Garrel, G.1    Simon, V.2    Thieulant, M.L.3    Cayla, X.4    Garcia, A.5    Counis, R.6    Cohen-Tannoudji, J.7
  • 37
    • 79952146228 scopus 로고    scopus 로고
    • PPARG regulates gonadotropin-releasing hormone signaling in LßT2 cells in vitro and pituitary gonadotroph function in vivo in mice
    • Sharma S, Sharma PM, Mistry DS, Chang RJ, Olefsky JM, Mellon PL, Webster NJ 2011 PPARG regulates gonadotropin-releasing hormone signaling in LßT2 cells in vitro and pituitary gonadotroph function in vivo in mice. Biol Reprod 84:466-475
    • (2011) Biol Reprod , vol.84 , pp. 466-475
    • Sharma, S.1    Sharma, P.M.2    Mistry, D.S.3    Chang, R.J.4    Olefsky, J.M.5    Mellon, P.L.6    Webster, N.J.7
  • 38
    • 34547489446 scopus 로고    scopus 로고
    • Effects of peroxisome proliferator-activated receptor activation on gonadotropin transcription and cell mitosis induced by bone morphogenetic proteins in mouse gonadotrope LßT2 cells
    • DOI 10.1677/JOE-07-0138
    • Takeda M, Otsuka F, Otani H, Inagaki K, Miyoshi T, Suzuki J, Mimura Y, Ogura T, Makino H 2007 Effects of peroxisome proliferator- activated receptor activation on gonadotropin transcription and cell mitosis induced by bone morphogenetic proteins in mouse gonadotrope LßT2 cells. J Endocrinol 194:87-99 (Pubitemid 47162890)
    • (2007) Journal of Endocrinology , vol.194 , Issue.1 , pp. 87-99
    • Takeda, M.1    Otsuka, F.2    Otani, H.3    Inagaki, K.4    Miyoshi, T.5    Suzuki, J.6    Mimura, Y.7    Ogura, T.8    Makino, H.9
  • 39
    • 0036218018 scopus 로고    scopus 로고
    • 2 gonadotrope cell lines
    • DOI 10.1210/en.143.4.1386
    • Junoy B, Maccario H, Mas JL, Enjalbert A, Drouva SV 2002 Proteasome implication in phorbol ester- and GnRH-induced selective down-regulation of PKC (α, ε, ζ) in α T(3)-1 and L β T(2) gonadotrope cell lines. Endocrinology 143:1386-1403 (Pubitemid 34274369)
    • (2002) Endocrinology , vol.143 , Issue.4 , pp. 1386-1403
    • Junoy, B.1    Maccario, H.2    Jean-Louis, M.A.S.3    Enjalbert, A.4    Drouva, S.V.5
  • 40
    • 2542629710 scopus 로고    scopus 로고
    • Protein kinase Cδ as gonadotropin-releasing hormone target isoenzyme in the αT3-1 gonadotrope cell line
    • DOI 10.1159/000078102
    • Maccario H, Junoy B, Poulin B, Boyer B, Enjalbert A, Drouva SV 2004 Protein kinase Cδ as gonadotropin-releasing hormone target isoenzyme in the αT3 - 1 gonadotrope cell line. Neuroendocrinology 79:204-220 (Pubitemid 38698123)
    • (2004) Neuroendocrinology , vol.79 , Issue.4 , pp. 204-220
    • Maccario, H.1    Junoy, B.2    Poulin, B.3    Boyer, B.4    Enjalbert, A.5    Drouva, S.V.6
  • 41
    • 1442348151 scopus 로고    scopus 로고
    • Dietary-Induced Obesity and Hypothalamic Infertility in Female DBA/2J Mice
    • DOI 10.1210/en.2003-1406
    • Tortoriello DV, McMinn J, Chua SC 2004 Dietary-induced obesity and hypothalamic infertility in female DBA/2J mice. Endocrinology 145:1238-1247 (Pubitemid 38281005)
    • (2004) Endocrinology , vol.145 , Issue.3 , pp. 1238-1247
    • Tortoriello, D.V.1    McMinn, J.2    Chua, S.C.3
  • 42
    • 0029061462 scopus 로고
    • Expression of gonadotropin-releasing hormone (GnRH) receptor gene is altered byGnRHagonist desensitization in a manner similar to that of gonadotropin β-subunit genes in normal and castrated rat pituitary
    • Lerrant Y, Kottler ML, Bergametti F, Moumni M, Blumberg-Tick J, Counis R 1995 Expression of gonadotropin-releasing hormone (GnRH) receptor gene is altered byGnRHagonist desensitization in a manner similar to that of gonadotropin β-subunit genes in normal and castrated rat pituitary. Endocrinology 136:2803-2808
    • (1995) Endocrinology , vol.136 , pp. 2803-2808
    • Lerrant, Y.1    Kottler, M.L.2    Bergametti, F.3    Moumni, M.4    Blumberg-Tick, J.5    Counis, R.6
  • 43
    • 0000009025 scopus 로고    scopus 로고
    • Gonadotropin biosynthesis
    • Neill JD, Knobil E, eds. New York: Academic Press
    • Counis R 1999 Gonadotropin biosynthesis. In: Neill JD, Knobil E, eds. Encyclopedia of reproduction, vol 2. New York: Academic Press; 507-520
    • (1999) Encyclopedia of Reproduction , vol.2 , pp. 507-520
    • Counis, R.1
  • 45
    • 0024314972 scopus 로고
    • Free fatty acids suppress growth hormone, but not luteinizing hormone, secretion in sheep
    • Estienne MJ, Schillo KK, Green MA, Boling JA 1989 Free fatty acids suppress growth hormone, but not luteinizing hormone, secretion in sheep. Endocrinology 125:85-91 (Pubitemid 19182645)
    • (1989) Endocrinology , vol.125 , Issue.1 , pp. 85-91
    • Estienne, M.J.1    Schillo, K.K.2    Green, M.A.3    Boling, J.A.4
  • 46
    • 0029300218 scopus 로고
    • Glucose and free fatty acid modulation of growth hormone and luteinizing hormone secretion by cultured porcine pituitary cells
    • Barb CR, Kraeling RR, Rampacek GB 1995 Glucose and free fatty acid modulation of growth hormone and luteinizing hormone secretion by cultured porcine pituitary cells. J Anim Sci 73:1416-1423
    • (1995) J Anim Sci , vol.73 , pp. 1416-1423
    • Barb, C.R.1    Kraeling, R.R.2    Rampacek, G.B.3
  • 48
    • 0028348472 scopus 로고
    • Effect of fatty acids on insulin release: Role of chain length and degree of unsaturation
    • Opara EC, Garfinkel M, Hubbard VS, Burch WM, Akwari OE 1994 Effect of fatty acids on insulin release: role of chain length and degree of unsaturation. Am J Physiol 266:E635-E639
    • (1994) Am J Physiol , vol.266
    • Opara, E.C.1    Garfinkel, M.2    Hubbard, V.S.3    Burch, W.M.4    Akwari, O.E.5
  • 49
    • 38649097529 scopus 로고    scopus 로고
    • Unsaturated fatty acids promote proliferation via ERK1/2 and Akt pathway in bovine mammary epithelial cells
    • Yonezawa T, Haga S, Kobayashi Y, Katoh K, Obara Y 2008 Unsaturated fatty acids promote proliferation via ERK1/2 and Akt pathway in bovine mammary epithelial cells. Biochem Biophys Res Commun 367:729-735
    • (2008) Biochem Biophys Res Commun , vol.367 , pp. 729-735
    • Yonezawa, T.1    Haga, S.2    Kobayashi, Y.3    Katoh, K.4    Obara, Y.5
  • 50
    • 12144268025 scopus 로고    scopus 로고
    • Beta oxidation in the brain is required for the effects of non-esterified fatty acids on glucose-induced insulin secretion in rats
    • DOI 10.1007/s00125-004-1569-2
    • Cruciani-Guglielmacci C, Hervalet A, Douared L, Sanders NM, Levin BE, Ktorza A, Magnan C 2004 β Oxidation in the brain is required for the effects of non-esterified fatty acids on glucose-induced insulin secretion in rats. Diabetologia 47:2032-2038 (Pubitemid 40110215)
    • (2004) Diabetologia , vol.47 , Issue.11 , pp. 2032-2038
    • Cruciani-Guglielmacci, C.1    Hervalet, A.2    Douared, L.3    Sanders, N.M.4    Levin, B.E.5    Ktorza, A.6    Magnan, C.7
  • 51
    • 58149095589 scopus 로고    scopus 로고
    • International Union of Pharmacology. LXXI. Free fatty acid receptors FFA1, -2, and -3: Pharmacology and pathophysiological functions
    • Stoddart LA, Smith NJ, Milligan G 2008 International Union of Pharmacology. LXXI. Free fatty acid receptors FFA1, -2, and -3: pharmacology and pathophysiological functions. Pharmacol Rev 60:405-417
    • (2008) Pharmacol Rev , vol.60 , pp. 405-417
    • Stoddart, L.A.1    Smith, N.J.2    Milligan, G.3
  • 52
    • 0029029066 scopus 로고
    • Arachidonic acid and free fatty acids as second messengers and the role of protein kinase C
    • Khan WA, Blobe GC, Hannun YA 1995 Arachidonic acid and free fatty acids as second messengers and the role of protein kinase C. Cell Signal 7:171-184
    • (1995) Cell Signal , vol.7 , pp. 171-184
    • Khan, W.A.1    Blobe, G.C.2    Hannun, Y.A.3
  • 54
    • 0031024191 scopus 로고    scopus 로고
    • 3 cells by perturbing the function of plasma membrane integral proteins
    • DOI 10.1210/en.138.1.264
    • Pérez FR, Casabiell X, Camiña JP, Zugaza JL, Casanueva FF 1997 cis-Unsaturated free fatty acids block growth hormone and prolactin secretion in thyrotropin-releasing hormone-stimulated GH3 cells by perturbing the function of plasma membrane integral proteins. Endocrinology 138:264-272 (Pubitemid 27009433)
    • (1997) Endocrinology , vol.138 , Issue.1 , pp. 264-272
    • Perez, F.R.1    Casabiell, X.2    Camina, J.P.3    Zugaza, J.L.4    Casanueva, F.F.5
  • 55
    • 58149348589 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid modulation of voltage-gated ion channels
    • Boland LM, Drzewiecki MM 2008 Polyunsaturated fatty acid modulation of voltage-gated ion channels. Cell Biochem Biophys 52:59-84
    • (2008) Cell Biochem Biophys , vol.52 , pp. 59-84
    • Boland, L.M.1    Drzewiecki, M.M.2
  • 56
    • 0041355360 scopus 로고    scopus 로고
    • Constitutive localization of the gonadotropin-releasing hormone (GnRH) receptor to low density membrane microdomains is necessary for GnRH signaling to ERK
    • DOI 10.1074/jbc.M304273200
    • Navratil AM, Bliss SP, Berghorn KA, Haughian JM, Farmerie TA, Graham JK, Clay CM, Roberson MS 2003 Constitutive localization of the gonadotropin- releasing hormone (GnRH) receptor to low density membrane microdomains is necessary for GnRH signaling to ERK. J Biol Chem 278:31593-31602 (Pubitemid 37048337)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.34 , pp. 31593-31602
    • Navratil, A.M.1    Bliss, S.P.2    Berghorn, K.A.3    Haughian, J.M.4    Farmerie, T.A.5    Graham, J.K.6    Clay, C.M.7    Roberson, M.S.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.