Fibrillization of human Tau is accelerated by exposure to lead via interaction with His-330 and His-362

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Zhu, Hai Li ^a   Meng, Sheng Rong ^a   Fan, Jun Bao ^a   Chen, Jie ^a   Liang, Yi ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

8 ANILINO 1 NAPHTHALENESULFONIC ACID; HISTONE; HISTONE H330; HISTONE H362; LEAD; MONOMER; NEUROFILAMENT PROTEIN; PEPTIDE FRAGMENT; TAU PROTEIN; THIOFLAVINE; UNCLASSIFIED DRUG; COMPLEMENTARY DNA; HEPARIN; HISTIDINE; MAPT PROTEIN, HUMAN; NEUROTOXIN; RECOMBINANT PROTEIN;

ALZHEIMER DISEASE; ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; ENZYME KINETICS; FIBER; HUMAN; HYDROPHOBICITY; INFRARED SPECTROSCOPY; LEAD POISONING; PH; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; WILD TYPE; CALORIMETRY; CHEMISTRY; METABOLISM; METHODOLOGY; MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SECONDARY STRUCTURE; TEMPERATURE; THERMODYNAMICS; TRANSMISSION ELECTRON MICROSCOPY;

ALZHEIMER DISEASE; CALORIMETRY; CIRCULAR DICHROISM; DNA, COMPLEMENTARY; HEPARIN; HISTIDINE; HUMANS; HYDROGEN-ION CONCENTRATION; LEAD; MICROSCOPY, ELECTRON, TRANSMISSION; MUTATION; NEUROTOXINS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; TAU PROTEINS; TEMPERATURE; THERMODYNAMICS;

EID: 80053144801     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025020     Document Type: Article

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