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Volumn 41, Issue 10, 2011, Pages 2966-2976

PD-L1 blockade overrides Salmonella typhimurium-mediated diabetes prevention in NOD mice: No role for Tregs

Author keywords

Autoimmunity; DCs; Inhibitory receptors; Tregs

Indexed keywords

CYCLOPHOSPHAMIDE; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; TRANSCRIPTION FACTOR FOXP3;

EID: 80053133748     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201141544     Document Type: Article
Times cited : (11)

References (38)
  • 1
    • 0032923558 scopus 로고    scopus 로고
    • Infection with Schistosoma mansoni prevents insulin dependent diabetes mellitus in non-obese diabetic mice
    • Cooke, A., Tonks, P., Jones, F. M., O'Shea, H., Hutchings, P., Fulford, A. J. and Dunne, D. W., Infection with Schistosoma mansoni prevents insulin dependent diabetes mellitus in non-obese diabetic mice. Parasite Immunol. 1999. 21: 169-176.
    • (1999) Parasite Immunol. , vol.21 , pp. 169-176
    • Cooke, A.1    Tonks, P.2    Jones, F.M.3    O'Shea, H.4    Hutchings, P.5    Fulford, A.J.6    Dunne, D.W.7
  • 2
    • 0038297115 scopus 로고    scopus 로고
    • Schistosoma mansoni antigens modulate the activity of the innate immune response and prevent onset of type 1 diabetes
    • Zaccone, P., Fehervari, Z., Jones, F. M., Sidobre, S., Kronenberg, M., Dunne, D. W. and Cooke, A., Schistosoma mansoni antigens modulate the activity of the innate immune response and prevent onset of type 1 diabetes. Eur. J. Immunol. 2003. 33: 1439-1449.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 1439-1449
    • Zaccone, P.1    Fehervari, Z.2    Jones, F.M.3    Sidobre, S.4    Kronenberg, M.5    Dunne, D.W.6    Cooke, A.7
  • 3
    • 65449180031 scopus 로고    scopus 로고
    • Schistosoma mansoni egg antigens induce Treg that participate in diabetes prevention in NOD mice
    • Zaccone, P., Burton, O., Miller, N., Jones, F. M., Dunne, D. W. and Cooke, A., Schistosoma mansoni egg antigens induce Treg that participate in diabetes prevention in NOD mice. Eur. J. Immunol. 2009. 39: 1098-1107.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 1098-1107
    • Zaccone, P.1    Burton, O.2    Miller, N.3    Jones, F.M.4    Dunne, D.W.5    Cooke, A.6
  • 4
    • 7044254968 scopus 로고    scopus 로고
    • Coxsackievirus B3 infection and type 1 diabetes development in NOD mice: insulitis determines susceptibility of pancreatic islets to virus infection
    • Drescher, K. M., Kono, K., Bopegamage, S., Carson, S. D. and Tracy, S., Coxsackievirus B3 infection and type 1 diabetes development in NOD mice: insulitis determines susceptibility of pancreatic islets to virus infection. Virology 2004. 329: 381-394.
    • (2004) Virology , vol.329 , pp. 381-394
    • Drescher, K.M.1    Kono, K.2    Bopegamage, S.3    Carson, S.D.4    Tracy, S.5
  • 5
    • 0029814323 scopus 로고    scopus 로고
    • Diabetes-prone NOD mice are resistant to Mycobacterium avium and the infection prevents autoimmune disease
    • Bras, A. and Aguas, A. P., Diabetes-prone NOD mice are resistant to Mycobacterium avium and the infection prevents autoimmune disease. Immunology 1996. 89: 20-25.
    • (1996) Immunology , vol.89 , pp. 20-25
    • Bras, A.1    Aguas, A.P.2
  • 6
    • 9244247590 scopus 로고    scopus 로고
    • Salmonella typhimurium infection halts development of type 1 diabetes in NOD mice
    • Zaccone, P., Raine, T., Sidobre, S., Kronenberg, M., Mastroeni, P. and Cooke, A., Salmonella typhimurium infection halts development of type 1 diabetes in NOD mice. Eur. J. Immunol. 2004. 34: 3246-3256.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 3246-3256
    • Zaccone, P.1    Raine, T.2    Sidobre, S.3    Kronenberg, M.4    Mastroeni, P.5    Cooke, A.6
  • 7
    • 33845994749 scopus 로고    scopus 로고
    • Inhibition of autoimmune type 1 diabetes by gastrointestinal helminth infection
    • Saunders, K. A., Raine, T., Cooke, A. and Lawrence, C. E., Inhibition of autoimmune type 1 diabetes by gastrointestinal helminth infection. Infect. Immun. 2007. 75: 397-407.
    • (2007) Infect. Immun. , vol.75 , pp. 397-407
    • Saunders, K.A.1    Raine, T.2    Cooke, A.3    Lawrence, C.E.4
  • 8
    • 38849130083 scopus 로고    scopus 로고
    • Murine gammaherpesvirus-68 infection alters self-antigen presentation and type 1 diabetes onset in NOD mice
    • Smith, K. A., Efstathiou, S. and Cooke, A., Murine gammaherpesvirus-68 infection alters self-antigen presentation and type 1 diabetes onset in NOD mice. J. Immunol. 2007. 179: 7325-7333.
    • (2007) J. Immunol. , vol.179 , pp. 7325-7333
    • Smith, K.A.1    Efstathiou, S.2    Cooke, A.3
  • 9
    • 33746904348 scopus 로고    scopus 로고
    • Salmonella typhimurium infection in nonobese diabetic mice generates immunomodulatory dendritic cells able to prevent type 1 diabetes
    • Raine, T., Zaccone, P., Mastroeni, P. and Cooke, A., Salmonella typhimurium infection in nonobese diabetic mice generates immunomodulatory dendritic cells able to prevent type 1 diabetes. J. Immunol. 2006. 177: 2224-2233.
    • (2006) J. Immunol. , vol.177 , pp. 2224-2233
    • Raine, T.1    Zaccone, P.2    Mastroeni, P.3    Cooke, A.4
  • 10
    • 0027420789 scopus 로고
    • Immunization with live versus killed Salmonella typhimurium leads to the generation of an IFN-gamma-dominant versus an IL-4-dominant immune response
    • Thatte, J., Rath, S. and Bal, V., Immunization with live versus killed Salmonella typhimurium leads to the generation of an IFN-gamma-dominant versus an IL-4-dominant immune response. Int. Immunol. 1993. 5: 1431-1436.
    • (1993) Int. Immunol. , vol.5 , pp. 1431-1436
    • Thatte, J.1    Rath, S.2    Bal, V.3
  • 11
    • 0029030964 scopus 로고
    • T helper cell subsets in insulin-dependent diabetes
    • Katz, J. D., Benoist, C. and Mathis, D., T helper cell subsets in insulin-dependent diabetes. Science 1995. 268: 1185-1188.
    • (1995) Science , vol.268 , pp. 1185-1188
    • Katz, J.D.1    Benoist, C.2    Mathis, D.3
  • 12
    • 77954966127 scopus 로고    scopus 로고
    • PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice
    • Mueller, S. N., Vanguri, V. K., Ha, S. J., West, E. E., Keir, M. E., Glickman, J. N., Sharpe, A. H. and Ahmed, R., PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice. J. Clin. Invest. 2010. 120: 2508-2515.
    • (2010) J. Clin. Invest. , vol.120 , pp. 2508-2515
    • Mueller, S.N.1    Vanguri, V.K.2    Ha, S.J.3    West, E.E.4    Keir, M.E.5    Glickman, J.N.6    Sharpe, A.H.7    Ahmed, R.8
  • 13
    • 0037477605 scopus 로고    scopus 로고
    • The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice
    • Ansari, M. J., Salama, A. D., Chitnis, T., Smith, R. N., Yagita, H., Akiba, H., Yamazaki, T. et al., The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice. J. Exp. Med. 2003. 198: 63-69.
    • (2003) J. Exp. Med. , vol.198 , pp. 63-69
    • Ansari, M.J.1    Salama, A.D.2    Chitnis, T.3    Smith, R.N.4    Yagita, H.5    Akiba, H.6    Yamazaki, T.7
  • 14
    • 4444317516 scopus 로고    scopus 로고
    • PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3zeta signalosome and downstream signaling to PKCtheta
    • Sheppard, K. A., Fitz, L. J., Lee, J. M., Benander, C., George, J. A., Wooters, J., Qiu, Y. et al., PD-1 inhibits T-cell receptor induced phosphorylation of the ZAP70/CD3zeta signalosome and downstream signaling to PKCtheta. FEBS Lett. 2004. 574: 37-41.
    • (2004) FEBS Lett. , vol.574 , pp. 37-41
    • Sheppard, K.A.1    Fitz, L.J.2    Lee, J.M.3    Benander, C.4    George, J.A.5    Wooters, J.6    Qiu, Y.7
  • 15
    • 70350433514 scopus 로고    scopus 로고
    • Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal
    • Fife, B. T., Pauken, K. E., Eagar, T. N., Obu, T., Wu, J., Tang, Q., Azuma, M. et al., Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal. Nat. Immunol. 2009. 10: 1185-1192.
    • (2009) Nat. Immunol. , vol.10 , pp. 1185-1192
    • Fife, B.T.1    Pauken, K.E.2    Eagar, T.N.3    Obu, T.4    Wu, J.5    Tang, Q.6    Azuma, M.7
  • 16
    • 77955359941 scopus 로고    scopus 로고
    • Deficiency in B7-H1 (PD-L1)/PD-1 coinhibition triggers pancreatic beta-cell destruction by insulin-specific, murine CD8 T-cells
    • Rajasalu, T., Brosi, H., Schuster, C., Spyrantis, A., Boehm, B. O., Chen, L., Reimann, J. and Schirmbeck, R., Deficiency in B7-H1 (PD-L1)/PD-1 coinhibition triggers pancreatic beta-cell destruction by insulin-specific, murine CD8 T-cells. Diabetes 2010. 59: 1966-1973.
    • (2010) Diabetes , vol.59 , pp. 1966-1973
    • Rajasalu, T.1    Brosi, H.2    Schuster, C.3    Spyrantis, A.4    Boehm, B.O.5    Chen, L.6    Reimann, J.7    Schirmbeck, R.8
  • 17
    • 50949129546 scopus 로고    scopus 로고
    • Effect of attenuation of Treg during BCG immunization on anti-mycobacterial Th1 responses and protection against Mycobacterium tuberculosis
    • Jaron, B., Maranghi, E., Leclerc, C. and Majlessi, L., Effect of attenuation of Treg during BCG immunization on anti-mycobacterial Th1 responses and protection against Mycobacterium tuberculosis. PLoS One 2008. 3: e2833.
    • (2008) PLoS One , vol.3
    • Jaron, B.1    Maranghi, E.2    Leclerc, C.3    Majlessi, L.4
  • 18
  • 20
    • 41949141343 scopus 로고    scopus 로고
    • Immune-potentiating effects of the chemotherapeutic drug cyclophosphamide
    • Brode, S. and Cooke, A., Immune-potentiating effects of the chemotherapeutic drug cyclophosphamide. Crit. Rev. Immunol. 2008. 28: 109-126.
    • (2008) Crit. Rev. Immunol. , vol.28 , pp. 109-126
    • Brode, S.1    Cooke, A.2
  • 21
    • 77957729952 scopus 로고    scopus 로고
    • An immunohistochemical study on the distribution and frequency of T regulatory cells in pancreatic islets of NOD mice during various stages of spontaneous and cyclophosphamide-accelerated diabetes
    • Kaur, S., Tan, W. L., Soo, C., Cheung, C. C., Stewart, J. and Reddy, S., An immunohistochemical study on the distribution and frequency of T regulatory cells in pancreatic islets of NOD mice during various stages of spontaneous and cyclophosphamide-accelerated diabetes. Pancreas 2010. 39: 1024-1033.
    • (2010) Pancreas , vol.39 , pp. 1024-1033
    • Kaur, S.1    Tan, W.L.2    Soo, C.3    Cheung, C.C.4    Stewart, J.5    Reddy, S.6
  • 23
    • 18944379171 scopus 로고    scopus 로고
    • + regulatory T cells play a critical role in granulocyte-macrophage colony-stimulating factor-induced suppression of experimental autoimmune thyroiditis
    • + regulatory T cells play a critical role in granulocyte-macrophage colony-stimulating factor-induced suppression of experimental autoimmune thyroiditis. J. Immunol. 2005. 174: 7006-7013.
    • (2005) J. Immunol. , vol.174 , pp. 7006-7013
    • Gangi, E.1    Vasu, C.2    Cheatem, D.3    Prabhakar, B.S.4
  • 24
    • 77958132478 scopus 로고    scopus 로고
    • Regulatory T cell suppressive potency dictates the balance between bacterial proliferation and clearance during persistent Salmonella infection
    • e1001043.
    • Johanns, T. M., Ertelt, J. M., Rowe, J. H. and Way, S. S., Regulatory T cell suppressive potency dictates the balance between bacterial proliferation and clearance during persistent Salmonella infection. PLoS Pathog. 2010. 6: e1001043.
    • (2010) PLoS Pathog. , vol.6
    • Johanns, T.M.1    Ertelt, J.M.2    Rowe, J.H.3    Way, S.S.4
  • 26
    • 54549096767 scopus 로고    scopus 로고
    • CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease
    • Hadeiba, H., Sato, T., Habtezion, A., Oderup, C., Pan, J. and Butcher, E. C., CCR9 expression defines tolerogenic plasmacytoid dendritic cells able to suppress acute graft-versus-host disease. Nat. Immunol. 2008. 9: 1253-1260.
    • (2008) Nat. Immunol. , vol.9 , pp. 1253-1260
    • Hadeiba, H.1    Sato, T.2    Habtezion, A.3    Oderup, C.4    Pan, J.5    Butcher, E.C.6
  • 27
    • 79953102525 scopus 로고    scopus 로고
    • Targeting MOG expression to dendritic cells delays onset of experimental autoimmune disease
    • Ko, H. J., Chung, J. Y., Nasa, Z., Chan, J., Siatskas, C., Toh, B. H. and Alderuccio, F., Targeting MOG expression to dendritic cells delays onset of experimental autoimmune disease. Autoimmunity 2011. 44: 177-187.
    • (2011) Autoimmunity , vol.44 , pp. 177-187
    • Ko, H.J.1    Chung, J.Y.2    Nasa, Z.3    Chan, J.4    Siatskas, C.5    Toh, B.H.6    Alderuccio, F.7
  • 28
    • 40449124650 scopus 로고    scopus 로고
    • Protective role of interleukin-10-producing regulatory dendritic cells against murine autoimmune gastritis
    • Torisu, M., Murakami, H., Akbar, F., Matsui, H., Hiasa, Y., Matsuura, B. and Onji, M., Protective role of interleukin-10-producing regulatory dendritic cells against murine autoimmune gastritis. J. Gastroenterol. 2008. 43: 100-107.
    • (2008) J. Gastroenterol. , vol.43 , pp. 100-107
    • Torisu, M.1    Murakami, H.2    Akbar, F.3    Matsui, H.4    Hiasa, Y.5    Matsuura, B.6    Onji, M.7
  • 29
    • 78049398483 scopus 로고    scopus 로고
    • Dendritic cells induce regulatory T cell proliferation through antigen-dependent and -independent interactions
    • Zou, T., Caton, A. J., Koretzky, G. A. and Kambayashi, T., Dendritic cells induce regulatory T cell proliferation through antigen-dependent and -independent interactions. J. Immunol. 2010. 185: 2790-2799.
    • (2010) J. Immunol. , vol.185 , pp. 2790-2799
    • Zou, T.1    Caton, A.J.2    Koretzky, G.A.3    Kambayashi, T.4
  • 30
    • 34247884612 scopus 로고    scopus 로고
    • The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection
    • Sharpe, A. H., Wherry, E. J., Ahmed, R. and Freeman, G. J., The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection. Nat. Immunol. 2007. 8: 239-245.
    • (2007) Nat. Immunol. , vol.8 , pp. 239-245
    • Sharpe, A.H.1    Wherry, E.J.2    Ahmed, R.3    Freeman, G.J.4
  • 31
    • 77956928620 scopus 로고    scopus 로고
    • B7-H1 (programmed cell death ligand 1) is required for the development of multifunctional Th1 cells and immunity to primary, but not secondary, Salmonella infection
    • Lee, S. J., O'Donnell, H. and McSorley, S. J., B7-H1 (programmed cell death ligand 1) is required for the development of multifunctional Th1 cells and immunity to primary, but not secondary, Salmonella infection. J. Immunol. 2010. 185: 2442-2449.
    • (2010) J. Immunol. , vol.185 , pp. 2442-2449
    • Lee, S.J.1    O'Donnell, H.2    McSorley, S.J.3
  • 32
    • 44449142522 scopus 로고    scopus 로고
    • Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway
    • Benedict, C. A., Loewendorf, A., Garcia, Z., Blazar, B. R. and Janssen, E. M., Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway. J. Immunol. 2008. 180: 4836-4847.
    • (2008) J. Immunol. , vol.180 , pp. 4836-4847
    • Benedict, C.A.1    Loewendorf, A.2    Garcia, Z.3    Blazar, B.R.4    Janssen, E.M.5
  • 33
    • 3142750528 scopus 로고    scopus 로고
    • Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages
    • Smith, P., Walsh, C. M., Mangan, N. E., Fallon, R. E., Sayers, J. R., McKenzie, A. N. and Fallon, P. G., Schistosoma mansoni worms induce anergy of T cells via selective up-regulation of programmed death ligand 1 on macrophages. J. Immunol. 2004. 173: 1240-1248.
    • (2004) J. Immunol. , vol.173 , pp. 1240-1248
    • Smith, P.1    Walsh, C.M.2    Mangan, N.E.3    Fallon, R.E.4    Sayers, J.R.5    McKenzie, A.N.6    Fallon, P.G.7
  • 34
    • 0242366612 scopus 로고    scopus 로고
    • Preferential contribution of B7-H1 to programmed death-1-mediated regulation of hapten-specific allergic inflammatory responses
    • Tsushima, F., Iwai, H., Otsuki, N., Abe, M., Hirose, S., Yamazaki, T., Akiba, H. et al., Preferential contribution of B7-H1 to programmed death-1-mediated regulation of hapten-specific allergic inflammatory responses. Eur. J. Immunol. 2003. 33: 2773-2782.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 2773-2782
    • Tsushima, F.1    Iwai, H.2    Otsuki, N.3    Abe, M.4    Hirose, S.5    Yamazaki, T.6    Akiba, H.7
  • 36
    • 9444225935 scopus 로고    scopus 로고
    • Java Treeview - extensible visualization of microarray data
    • Saldanha, A. J., Java Treeview - extensible visualization of microarray data. Bioinformatics 2004. 20: 3246-3248.
    • (2004) Bioinformatics , vol.20 , pp. 3246-3248
    • Saldanha, A.J.1
  • 37
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak, K. J. and Schmittgen, T. D., Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001. 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2


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