Expression of bcl-2 and box in TGF-β1-induced apoptosis of L1210 leukemic cells

European Journal of Cell Biology

Volumn 75, Issue 4, 1998, Pages 367-374

  Motyl, Tomasz ^a   Grzelkowska, Katarzyna ^a   Zimowska, Wioletta ^a   Skierski, Janusz ^b   Warȩski, Przemysław ^a   Płoszaj, Tomasz ^a   Trzeciak, Lech ^c  

^a WARSAW UNIVERSITY OF LIFE SCIENCES   (Poland)

^b NATIONAL MEDICINES INSTITUTE   (Poland)

^c MEDICAL CENTER FOR POSTGRADUATE EDUCATION   (Poland)

Author keywords

Apoptosis; Bax; Bcl 2; Reactive oxygen species; TGF 1

Indexed keywords

CELL DNA; DNA FRAGMENT; FLUORESCEIN ISOTHIOCYANATE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; REGULATOR PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL CYCLE S PHASE; CELL DEATH; CELL STRUCTURE; CHROMATIN CONDENSATION; CONTROLLED STUDY; DIPLOIDY; DNA CLEAVAGE; DNA CONTENT; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENETIC TRANSCRIPTION; HOUSEKEEPING GENE; LEUKEMIA CELL; MOLECULAR GENETICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0031967404     PISSN: 01719335     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0171-9335(98)80070-8     Document Type: Article

References (43)

1. Alexandrow, M. G., H. L. Moses: Transforming growth factor β and cell cycle regulation. Cancer Res. 55, 1452-1457 (1994).
2. Attisano, L., J. L. Wrana, F. López-Casillas, J. Massagué: TGF-β receptors and actions. Biochim. Biophys. Acta 1222, 71-80 (1994).
3. Baker, A. M., M. M. Briehl, R. Dorr, G. Powis: Decreased antioxidant defence and increased oxidant stress during dexamethasone-induced apoptosis: bcl-2 prevents the loss of antioxidant enzyme activity. Cell Death and Differ. 3, 207-213 (1996).
4. Blachowski, S., T. Motyl, A. Orzechowski, K. Grzelkowska, B. Bałasińska: Comparison of metabolic effects of EGF, TGF-α, and TGF-β1 in primary culture of fetal bovine myoblasts and rat L6 myoblasts. Int. J. Biochem. 11, 1571-1577 (1993).
5. Douglas, R. S., R. J. Capocasale, R. J. Lamb, P. C. Nowell, J. S. Moore: Chronic lymphocytic leukemia B cells are resistant to the apoptotic effects of transforming growth factor-β. Blood 3, 941-947 (1997).
6. Fukuda, K., M. Kojiro, J.-F. Chiu: Induction of apoptosis by transforming growth factor-β1 in the rat hepatoma cell line McARH7777: a possible association with tissue transglutaminase expression. Hepatology 4, 945-953 (1993).
7. Fynan,T. M., M. D. Reiss: Resistance to inhibition of cell growth by transforming growth factor-β and its role in oncogenesis. Crit. Rev. Oncogenesis 5, 493-540 (1993).
8. Gong, J., F. Traganos, Z. Darzynkiewicz: A selective procedure for DNA extraction from apoptotic cells applicable for gel electrophoresis and flow cytometry. Anal. Biochem. 218, 314-319 (1994).
9. Gross, A.: Regulation of apoptosis by the Bcl-2 family members. 3rd Winter Research Conference on Oxidative Stress and Apoptosis. Les Arcs, France 1997.
10. Grzelkowska, K., T. Motyl, E. Malicka, J. Ostrowski, L. Trzeciak, M. Filipecki: Effect of orotic acid on TGF-β1-induced growth inhibition of L1210 leukemic cells. Int. J. Hematol. 61, 23-33 (1995).
11. Häcker G., D. L. Vaux: A sticky business. Curr. Biol. 6, 61-63 (1995).
12. Hockenbery, D. M, Z. N. Oltvai, X.-M. Yin, C. L. Milliman, S. J. Korsmeyer: Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75, 241-251 (1993).
13. Kayanoki, Y., J. Fujii, K. Suzuki, S. Kawata, Y. Matsuzawa, N. Taniguchi: Supression of antioxidative enzyme expression by transforming growth factor-β1 in rat hepatocytes. J. Biol. Chem. 269, 15488-15492 (1994).
14. Knudson, C. M., K. S. Tung, W. G. Tourtellotte, G. A. Brown, S. J. Korsmeyer: Bax-deficient mice with lymphoid hyperplasia and male germ cell death. Science 270, 96-99 (1995).
15. Kroemer, G.: The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nature Med. 3, 614-620 (1997).
16. Lafon, C. L., C. Mathieu, M. Guerrin, O. Pierre, S. Vidal, A. Valette: Transforming growth factor β1-induced apoptosis in human ovarian carcinoma cells: protection by antioxidant N-acetylcysteine and bcl-2. Cell Growth and Differ. 7, 1095-1104 (1996).
17. 2+ fluxes. Med. Sci. 91, 6569-6573 (1994).
18. Leof, E. B., J. A. Proper, A. S. Goustin, G. D. Shipley, P. E. DiCorleto, H. L. Moses: Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor-β: a proposed model for indirect mitogenesis involving autocrine activity. Proc. Natl. Acad. Sci. USA 83, 2453-2457 (1986).
19. Liu, X., C. M. Kim, J. Yang, R. Jemmerson, X. Wang: Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 12, 147-157 (1996).
20. Lotem, J., L. Sachs: Hematopoietic cytokines inhibit apoptosis induced by transforming growth factor β1 and cancer chemotherapy compounds in myeloid leukemic cells. Blood 80, 1750-1757 (1992).
21. Maccarrone, M., W. F. Nieuwenhuizen, H. F. Dullens, M. V. Catani, G. Mielino, G. A. Veldink, J. F. Vliegenthart, A. F. Agro: Membrane modifications in human erythroleukemia K562 cells during induction of programmed cell death by transforming growth factor β1 or cisplatin. Eur. J. Biochem. 241, 297-302 (1996).
22. Markowitz, S. D., A. B. Roberts: Tumor suppressor activity of the TGF-β pathway in human cancers. Cytokine and Growth Factor Rev. 1, 93-102 (1996).
23. Massague, J.: The transforming growth factors-β family. Annu. Rev. Cell Biol. 6, 597-641 (1990).
24. McDonnell, T. J., A. Beham, M. Sarkiss, M. M. Andersen, P. Lo: Importance of Bcl-2 family in cell death regulation. Experientia 52, 1008-1017 (1996).
25. Motyl, T., M. Kasterka, K. Grzelkowska, J. Ostrowski, M. Filipecki, E. Malicka, T. Płoszaj: Phorbol ester (12-O-tetra-decanoylphorbol 13-acetate) prevents ornithine decarboxylase inhibition and apoptosis in L1210 leukemic cells exposed to TGF-β1. Int. J. Biochem. Cell Biol. 28, 1327-1335 (1996).
26. Motyl, T., M. Kasterka, K. Grzelkowska, S. Blachowski, P. Sysa: TGF-β1 inhibits polyamine biosynthesis in K562 leukemic cells. Ann. Hematol. 67, 285-288 (1993).
27. Muchmore, S. W., M. Sattler, H. Liang, R. P. Meadows, J. E. Harlan, H. S. Yoon, D. Nettesheim, B. S. Chang, C. B. Thompson, S.-L.Wong, S.-C. Ng, S. W. Fesik: X-ray and NMR structure of human Bcl-xl, an inhibitor of programmed cell death. Nature 381, 335-341 (1996).
28. Ohba, M., M. Shibanuma, M. Kuroki, K. Nose: Production of hydrogen peroxide by transforming growth factor-β1 and its involvement in induction of egr-1 in mouse osteoblastic cells. J. Cell Biol. 126, 1079-1088 (1994).
29. Pollack, A., G. Ciancio: Cell cycle phase-specific analysis of cell viability using Hoechst 33342 and propidium iodide after ethanol preservation. In: Z. Darzynkiewicz, K. A. Crissman (eds.): Flow Cytometry. pp. 19-24. Academic Press San Diego 1991.
30. Reed, C. J.: Mechanisms of Bcl-2 family protein function and dysfunction in health and disease. Behring Inst. Mitt. 97, 72-100 (1996).
31. Roberts, A. B., M. A. Anzano, L. M. Wakefield, N. S. Roche, D. F. Stern, M. B. Sporn: Type β transforming growth factor a bifunctional regulator of cellular growth. Proc. Natl. Acad. Sci. USA 82, 119-123 (1985).
32. Rotello, R. J., R. C. Lieberman, A. F. Purchio, L. E. Gerschenson: Coordinated regulation of apoptosis and cell proliferation by transforming growth factor β in cultured murine epithelial cells. Proc. Natl. Acad. Sci. USA 88, 3412-3415 (1991).
33. Sánchez, A, A. M. Álvarez, M. Benito, I. Fabregat: Apoptosis induced by transforming growth factor-β in fetal hepatocyte primary cultures. J. Biol. Chem. 13, 7416-7422 (1996).
34. Satoh, T., N. Sakai, Y. Enokido, Y. Uchiyama, H. Hatanaka: Survival factor-insensitive generation of reactive oxygen species induced by serum deprivation in neuronal cells. Brain Res. 733, 9-14 (1996).
35. Selvakumaran, M., H.-K. Lin, R. Tjin Tham Sjin, J. C. Reed, D. A. Liebermann, B. Hoffman: The novel primary response gene MyD118 and the protooncogenes myb, myc, and bcl-2 modulate transforming growth factor β1-induced apoptosis of myeloid leukemia cells. Mol. Cell. Biol. 4, 2352-2360 (1994).
36. Soma, Y. G. R. Grotendorst: TGF-beta stimulates primary human fibroblast DNA synthesis via an autocrine production of PDGF-related peptides. J. Cell. Physiol. 140, 246-253 (1989).
37. Taetle, R., C. Payne, B. D. Santos, M. Russell, P. Segarini: Effects of transforming growth factor β1 on growth and apoptosis of human acute myelogenous leukemia cells. Cancer Research 53, 3386-3393 (1993).
38. 2 release from bovine pulmonary artery endothelial cells induced by TGF-β1. Am. J. Physiol. 265, L622-L626 (1993).
39. Theodorescu, D., R. S. Kerbel, C. Sheehan: TGF-β1 gene expression depends on tissue architecture. In Vitro Cell. Dev. Biol. 29A, 105-108 (1993).
40. Tsukada, T., K. Eguchi, K. Migita, Y. Kawabe, A. Kawakami, N. Matsuoka, H. Takashima, A. Mizokami, S. Nagataki: Transforming growth factor β1 induces apoptotic cell death in cultured human umbilical vein endothelial cells with down-regulated expression of Bcl-2. Biochem. Biophys. Res. Commun. 3, 1076-1082 (1995).
41. Tu, H., S. C. Jacobs, A. Borkowski, N. Kyprianou: Incidence of apoptosis and cell proliferation in prostate cancer: relationship with TGF-β1 and bcl-2 expression. Int. J. Cancer 69, 357-363 (1996).
42. Wright, J. A., E. A. Turley, A. H. Greenberg: Transforming growth factor beta and fibroblast growth factor as promoters of tumor progression to malignancy. Crit. Rev. Oncogenesis 4, 473-492 (1993).
43. Yamamoto, M., Y. Maehara, Y. Sakaguchi, T. Kusumoto, Y. Ichiyoshi, K. Sugimachi: Transforming growth factor-β1 induces apoptosis in gastric cancer cells throught a p53-independent pathway. Cancer (Suppl.) 8, 1628-1633 (1996).