Cycloheximide blocks TGF-β1-induced apoptosis in murine hepatocytes

Acta Pharmacologica Sinica

Volumn 22, Issue 2, 2001, Pages 176-182

  Liao, J H ^a   Zhou, B H ^a   Chai, M Q ^a   Song, J G ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Apoptosis; Ceramides; Cycloheximide; Transforming growth factor

Indexed keywords

CERAMIDE; CRYSTAL VIOLET; CYCLOHEXIMIDE; DNA FRAGMENT; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN BAX; PROTEIN P53; TRANSFORMING GROWTH FACTOR BETA1; MAPK KINASE KINASE 7; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; ONCOPROTEIN; PROTEIN SYNTHESIS INHIBITOR; PROTO ONCOGENE PROTEINS; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL LYSATE; CELL VIABILITY; CHROMATIN CONDENSATION; CONTROLLED STUDY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; IMMUNOBLOTTING; LIVER CELL; MOUSE; NONHUMAN; PROTEIN SYNTHESIS; THIN LAYER CHROMATOGRAPHY; ANIMAL; CYTOLOGY; DRUG EFFECT; METABOLISM;

ANIMAL; APOPTOSIS; CERAMIDES; CYCLOHEXIMIDE; HEPATOCYTES; MAP KINASE KINASE KINASES; MICE; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN P53; PROTEIN SYNTHESIS INHIBITORS; PROTO-ONCOGENE PROTEINS; SUPPORT, NON-U.S. GOV'T; TRANSFORMING GROWTH FACTOR BETA;

EID: 0035137544     PISSN: 02539756     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. TGF-β receptor signaling
2. TGF-β signaling from cell membrane to nucleus through smad proteins
3. Identification of a member of the MAPKKK family as a potential mediator of TGF-β signal transduction
4. Apoptosis induced by serum deprivation of PC12 cells is not preceded by growth arrest and can occur at each phase of the cell cycle
5. V-Src increases diacylglycerol levels via a type D phospholipase-mediated hydrolysis of phosphatidylcholine
6. 1 initiated apoptosis in rat liver epithelial cells
7. 1-induced apoptosis in rat hepatoma cells: A possible association with Bcl-xL induction
8. Hematopoietic progenitor kinase 1 is a component of transforming growth factor β-induced c-Jun N-terminal kinase signaling cascade
9. TAK1 mediates the ceramide signaling to stress-activated protein kinase/c-Jun N-terminal kinase