Vitisin B, a resveratrol tetramer, inhibits migration through inhibition of PDGF signaling and enhancement of cell adhesiveness in cultured vascular smooth muscle cells

Toxicology and Applied Pharmacology

Volumn 256, Issue 2, 2011, Pages 198-208

  Ong, Eng Thaim ^a   Hwang, Tsong Long ^b   Huang, Yu Ling ^c,d   Lin, Chwan Fwu ^d   Wu, Wen Bin ^e  

^a CATHAY GENERAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

^d CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^e FU JEN CATHOLIC UNIVERSITY   (Taiwan)

Author keywords

Adhesiveness; Cardiovascular disease; Migration; PDGF; Resveratrol; Stilbene; Vascular smooth muscle cell

Indexed keywords

ACTIN; AMPELOPSIN A; AMPELOPSIN C; ANTIMITOTIC AGENT; ESTROGEN RECEPTOR; FOCAL ADHESION KINASE; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHOPROTEIN; PHOSPHOTYROSINE; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR BB; PROTEIN KINASE B; PROTEIN TYROSINE KINASE INHIBITOR; RESVERATROL; STILBENE DERIVATIVE; TETRAMER; UNCLASSIFIED DRUG; VINIFERIN; VITISIN A; VITISIN B;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL MEMBRANE; CELL MIGRATION; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSKELETON; CYTOSOL; DRUG EFFECT; ENZYME ACTIVITY; FLUORESCENCE MICROSCOPY; FOCAL ADHESION; NONHUMAN; PROTEIN BINDING; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; TIME; VASCULAR SMOOTH MUSCLE;

ANIMALS; BENZOFURANS; BLOTTING, WESTERN; CELL ADHESION; CELL MIGRATION ASSAYS; CELL MOVEMENT; CELLS, CULTURED; FLOW CYTOMETRY; MICROSCOPY, FLUORESCENCE; MUSCLE, SMOOTH, VASCULAR; PHENOLS; PLATELET-DERIVED GROWTH FACTOR; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION;

VITACEAE;

EID: 80053131848     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2011.08.013     Document Type: Article

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