Allergenicity assessment of the papaya ringspot virus coat protein expressed in transgenic rainbow papaya

Journal of Agricultural and Food Chemistry

Volumn 59, Issue 18, 2011, Pages 10006-10013

  Fermín, Gustavo ^a,b,c   Keith, Ronald C ^a   Suzuki, Jon Y ^a   Ferreira, Stephen A ^b   Gaskill, Douglas A ^b   Pitz, Karen Y ^b   Manshardt, Richard M ^b   Gonsalves, Dennis ^a   Tripathi, Savarni ^a,b  

^a U S DEPARTMENT OF AGRICULTURE   (United States)

^b UNIVERSITY OF HAWAII AT MANOA   (United States)

^c UNIVERSIDAD DE LOS ANDES   (Venezuela)

Author keywords

allergenicity; coat protein; papaya ringspot virus; Rainbow; transgenic papaya

Indexed keywords

ALLERGENICITY; COAT PROTEINS; PAPAYA RINGSPOT VIRUS; RAINBOW; TRANSGENICS;

AMINO ACIDS; ANTIGENS; BIOINFORMATICS; GENES; PROTEINS; RATING; VIRUSES;

ALLERGIES;

ALLERGEN; CAPSID PROTEIN; VIRUS ANTIGEN;

ARTICLE; CARICA; CHEMISTRY; DRUG STABILITY; FOOD ALLERGY; FRUIT; GENETICS; HEAT; HUMAN; IMMUNOLOGY; POTYVIRUS; TRANSGENIC PLANT; VIROLOGY;

ALLERGENS; ANTIGENS, VIRAL; CAPSID PROTEINS; CARICA; DRUG STABILITY; FOOD HYPERSENSITIVITY; FRUIT; HOT TEMPERATURE; HUMANS; PLANTS, GENETICALLY MODIFIED; POTYVIRUS;

CARICA PAPAYA; PAPAYA RINGSPOT VIRUS;

EID: 80053111822     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf201194r     Document Type: Article

References (42)

1. Sanford, J. C.; Johnston, S. A. The concept of parasite-derived resistance-Deriving resistance genes from the parasite's own genome J. Theor. Biol. 1985, 113, 395-405 (Pubitemid 16237868)
2. Gonsalves, D.; Suzuki, J.; Tripathi, S.; Ferreira, S. Papaya ringspot virus (Potyviridae). In Encyclopedia of Virology, 3 rd ed., 5 vols.; Mahy, B.; Van Regenmortel, M., Eds.; Elsevier: Oxford, U.K., 2008; Vol. 4, pp 1-8.
3. Gonsalves, D. Control of papaya ringspot virus in papaya: A case study Annu. Rev. Phytopathol. 1998, 36, 415-437 (Pubitemid 28456415)
4. NASS, USDA National Agricultural Statistics Service. http://www.nass. usda.gov/hi, 2009, (accessed May 2011).
5. Manshardt, R. M. 'UH Rainbow' papaya. New Plants for Hawaii-1; University of Hawaii College of Tropical Agriculture and Human Resources: Honolulu, 1999; Vol. 1, 2 pp.
6. Tripathi, S.; Suzuki, J. Y.; Carr, J. B.; McQuate, G. T.; Ferreira, S. A.; Manshardt, R. M.; Pitz, K. Y.; Wall, M. M.; Gonsalves, D. Nutritional composition of Rainbow papaya, the first commercialized transgenic fruit crop J. Food Compos. Anal. 2011, 24 (2) 140-147
7. Astwood, J. D.; Leach, J. N.; Fuchs, R. L. Stability of food allergens to digestion in vitro Nat. Biotechnol. 1996, 14 (10) 1269-1273 (Pubitemid 26332788)
8. Codex. Codex Principles and Guidelines on Foods Derived from Biotechnology; Food and Agriculture Organization of the United Nations: Rome, Italy, 2003.
9. FAO/WHO. Allergenicity of Genetically Modified Foods; Food and Agriculture Organization of the United Nations: Rome, Italy, 2001.
10. Fu, T. J.; Abbott, U. R.; Hatzos, C. Digestibility of food allergens and nonallergenic proteins in simulated gastric fluid and simulated intestinal fluid-A comparative study J. Agric. Food Chem. 2002, 50 (24) 7154-7160 (Pubitemid 35332799)
11. Harrison, L. A.; Bailey, M. R.; Naylor, M. W.; Ream, J. E.; Hammond, B. G.; Nida, D. L.; Burnette, B. L.; Nickson, T. E.; Mitsky, T. A.; Taylor, M. L.; Fuchs, R. L.; Padgette, S. R. The expressed protein in glyphosate-tolerant soybean, 5-enolpyruviylshikimate-3-phosphate synthase from Agrobacterium sp strain CP4, is rapidly digested in vitro and is not toxic to acutely gavaged mice J. Nutr. 1996, 126, 738-740
12. Herman, R. A.; Storer, N. P.; Gao, Y. Digestion assays in allergenicity assessment of transgenic proteins Environ. Health Perspect. 2006, 114 (8) 1154-1157 (Pubitemid 44184670)
13. Roesler, K. R.; Rao, A. G. Rapid gastric fluid digestion and biochemical characterization of engineered proteins enriched in essential aminoacids J. Agric. Food Chem. 2001, 49, 3443-3451 (Pubitemid 32845082)
14. Taylor, S. L. Protein allergenicity assessment of foods produced through agricultural biotechnology Annu. Rev. Pharmacol. Toxicol. 2002, 42, 99-112 (Pubitemid 34160521)
15. Metcalfe, D. D.; Astwood, J. D.; Townsend, R.; Sampson, H. A.; Taylor, S. L.; Fuchs, R. L. Assessment of the allergenic potential of foods derived from genetically engineered crop plants Crit. Rev. Food Sci. Nutr. 1996, 36, 165-186
16. Ivanciuc, O.; Schein, C. H.; Braun, W. SDAP: Database and computational tools for allergenic proteins Nucleic Acids Res. 2003, 31, 359-362 (Pubitemid 36150403)
17. Gonsalves, D.; Ishii, M. Purification and serology of papaya ringspot virus Phytopathology 1980, 70, 1028-1032
18. Bradford, M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal. Biochem. 1976, 72, 248-254
19. Ling, K.; Namba, S.; Gonsalves, C.; Slightom, J. L.; Gonsalves, D. Protection against detrimental effects of potyvirus infection in transgenic tobacco plants expressing the papaya ringspot virus coat protein gene Bio/Technology 1991, 9 (8) 752-758
20. Sambrook, J.; Russell, D. W. Molecular Cloning; A Laboratory Manual, 3 rd ed., 3 vols.; Cold Spring Harbor Laboratory Press: Plainview, NY, 2001.
21. Hames, B.; Rickwood, D. Electrophoresis of Proteins: A Practical Approach; IRL Press: Oxford, U.K., 1981; Vol. 1, pp 13996-14003.
22. U.S. Pharmacopeia. The United States Pharmacopeia 24, 2000. Simulated gastric fluid, TS. In The National Formulary 19; Board of Trustees, Eds.; United States Pharmacopeial Convention, Inc.: Rockville, MD, 2000; p 2235.
23. Umezawa, H.; Aoyagi, T.; Morishima, H.; Matsuzaki, H.; Hamada, M.; Takeuchi, T. Pepstatin, a new pepsin inhibitor produced by Actinomycetes J. Antibiot. 1970, 23, 259-262
24. Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4 Nature 1970, 227, 680-685
25. Umezawa, H. Structures and activities of protease inhibitors of microbial origin Methods Enzymol. 1976, XLV, 675-695
26. Hiebert, E.; Tremaine, J. H.; Ronald, W. P. The effect of limited proteolysis on the amino acid composition of five potyviruses and on the serological reaction and peptide map of the tobacco etch virus capsid protein Phytopathology 1984, 74, 411-416
27. Fuchs, R. L.; Ream, J. E.; Hammond, B. G.; Naylor, M. W.; Leimgruber, R. M.; Berberich, S. A. Safety assessment of the neomycin phosphotransferase II (NPTII) protein Bio/Technology 1993, 11, 1543-1547
28. Gilissen, L. J. W.; Metz, P. L. J.; Stiekema, W. J.; Nap, J. P. Biosafety of E. coli beta-glucuronidase (GUS) in plants Transgenic Res. 1998, 7 (3) 157-163 (Pubitemid 28214294)
29. Ramessar, K.; Peremarti, A.; Gomez-Galera, S.; Naqvi, S.; Moralejo, M.; Munoz, P.; Capell, T.; Christou, P. Biosafety and risk assessment framework for selectable marker genes in transgenic crop plants: A case of the science not supporting the politics Transgenic Res. 2007, 16 (3) 261-280 (Pubitemid 46646810)
30. Suzuki, J. Y.; Tripathi, S.; Fermín, G. A.; Jan, F.-J.; Hou, S.; Saw, J. H.; Ackerman, C. M.; Yu, Q.; Schatz, M. C.; Pitz, K. Y.; Yépes, M.; Fitch, M. M. M.; Manshardt, R. M.; Slightom, J. L.; Ferreira, S. A.; Salzberg, S. L.; Alam, M.; Ming, R.; Moore, P. H.; Gonsalves, D. Characterization of inserton sites in Rainbow papaya, the first commercialized transgenic fruit crop Trop. Plant Biol. 2008, 1, 293-309
31. Kleter, G. A.; Peijnenburg, A. A. C. M. Screening of transgenic proteins expressed in transgenic food crops for the presence of short amino acid sequences identical to potential, IgE-binding linear epitopes of allergens BMC Struct. Biol. 2002, 2, 1-11 (Pubitemid 38994296)
32. Goodman, R. E.; Vieths, S.; Sampson, H. A.; Hill, D.; Ebisawa, M.; Taylor, S. L.; Van Ree, R. Allergenicity assessment of genetically modified crops-What makes sense? Nat. Biotechnol. 2008, 26 (1) 73-81
33. Silvanovich, A.; Nemeth, M. A.; Song, P.; Herman, R.; Tagliani, L.; Bannon, G. A. The value of short amino acid sequence matches for prediction of protein allergenicity Toxicol. Sci. 2006, 90 (1) 252-258 (Pubitemid 43264745)
34. Stadler, M. B.; Stadler, B. M. Allergenicity prediction by protein sequence FASEB J. 2003, 17 (9) 1141-1143
35. Ladics, G. S.; Bardina, L.; Cressman, R. F.; Mattsson, J. L.; Sampson, H. A. Lack of cross-reactivity between the Bacillus thuringiensis derived protein Cry1F in maize grain and dust mite Der p7 protein with human sera positive for Der p7-IgE Regul. Toxicol. Pharmacol. 2006, 44 (2) 136-143 (Pubitemid 43234288)
36. Ladics, G. S.; Cressman, R. F.; Herouet-Guicheney, C.; Herman, R. A.; Privalle, L.; Song, P.; Ward, J. M.; McClain, S. Bioinformatics and the allergy assessment of agricultural biotechnology products: Industry practices and recommendations Regul. Toxicol. Pharmacol. 2011, 60 (1) 46-53
37. Hileman, R. E.; Silvanovich, A.; Goodman, R. E.; Rice, E. A.; Holleschak, G.; Astwood, J. D.; Hefle, S. L. Bioinformatic methods for allergenicity assessment using a comprehensive allergen database Int. Arch. Allergy Immunol. 2002, 128 (4) 280-291
38. Suzuki, J. Y.; Tripathi, S.; Gonsalves, D. Virus resistant transgenic papaya: Commercial development and regulatory and environmental issues. In Biotechnology and Plant Disease Management; Punja, Z. K.; DeBoer, S.; Sanfaçon, H., Eds.; CAB International: Wallingford, U.K., 2007; pp 436-461.
39. Xia, Y.; Spence, H.; Moore, J.; Heaney, N.; McDermott, L.; Cooper, A.; Watson, D.; Mei, B.; Komuniecki, R.; Kennedy, M. The ABA-1 allergen of Ascaris lumbricoides: Sequence polymorphism, stage and tissue-specific expression, lipid binding function, and protein biophysical properties Parasitology 2000, 120 (02) 211-224 (Pubitemid 30107745)
40. Gasteiger, E.; Hoogland, C.; Gattiker, A.; Duvaud, S.; Wilkins, M. R.; Appel, R. D.; Bairoch, A. ExPASy PeptideCutter tool: Protein identification and analysis tools on the ExPASy server. In The Proteomics Protocols Handbook; Walker, J. M., Ed.; Humana Press, Inc.: Totowa, NJ, 2005; pp 571-607.
41. Hansen, K. S.; Ballmer-Weber, B. K.; Lüttkopf, D.; Skov, P. S.; Wüthrich, B.; Bindslev-Jensen, C.; Vieths, S.; Poulsen, L. K. Roasted hazelnuts-Allergenic activity evaluated by double-blind, placebo-controlled food challenge Allergy 2003, 58 (2) 132-138 (Pubitemid 36362008)
42. Mondoulet, L.; Paty, E.; Drumare, M. F.; Ah-Leung, S.; Scheinmann, P.; Willemot, R. M.; Wal, J. M.; Bernard, H. Influence of thermal processing on the allergenicity of peanut proteins J. Agric. Food Chem. 2005, 53 (11) 4547-4553 (Pubitemid 40855485)