In vivo measurement of age-related stiffening in the crystalline lens by Brillouin optical microscopy

Biophysical Journal

Volumn 101, Issue 6, 2011, Pages 1539-1545

  Scarcelli, Giuliano ^a,b   Kim, Pilhan ^a,b   Yun, Seok Hyun ^a,b,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGING; ANIMAL; ARTICLE; BIOMECHANICS; C57BL MOUSE; CATTLE; CYTOLOGY; LENS; LIGHT RELATED PHENOMENA; MECHANICS; METHODOLOGY; MICROSCOPY; MOUSE; PHYSIOLOGY; SWINE;

AGING; ANIMALS; BIOMECHANICS; CATTLE; LENS, CRYSTALLINE; MECHANICAL PROCESSES; MICE; MICE, INBRED C57BL; MICROSCOPY; OPTICAL PROCESSES; SWINE;

ANIMALIA; MUS;

EID: 80053097200     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2011.08.008     Document Type: Article

References (42)

1. P. Artal, and J. Tabernero The eye's aplanatic answer Nat. Photonics. 2 2008 586 589
2. H. Bloemendal The vertebrate eye lens Science 197 1977 127 138
3. R.C. Augusteyn On the growth and internal structure of the human lens Exp. Eye Res. 90 2010 643 654
4. G.B. Benedek Theory of transparency of the eye Appl. Opt. 10 1971 459 473
5. M. Delaye, and A. Tardieu Short-range order of crystallin proteins accounts for eye lens transparency Nature 302 1983 415 417 (Pubitemid 13164324)
6. J.Z. Xia, and Q.H. Wang J. Clauwaert Structural basis of eye lens transparency: light scattering by concentrated solutions of bovine α-crystallin proteins Biophys. J. 71 1996 2815 2822 (Pubitemid 26367743)
7. C.R. Ethier, M. Johnson, and J. Ruberti Ocular biomechanics and biotransport Annu. Rev. Biomed. Eng. 6 2004 249 273 (Pubitemid 39209499)
8. K.R. Heys, S.L. Cram, and R.J.W. Truscott Massive increase in the stiffness of the human lens nucleus with age: the basis for presbyopia? Mol. Vis. 10 2004 956 963 (Pubitemid 41358196)
9. S.J. McGinty, and R.J.W. Truscott Presbyopia: the first stage of nuclear cataract? Ophthalmic Res. 38 2006 137 148 (Pubitemid 43780873)
10. A. Glasser, and M.C.W. Campbell Biometric, optical and physical changes in the isolated human crystalline lens with age in relation to presbyopia Vision Res. 39 1999 1991 2015 (Pubitemid 29156718)
11. H.A. Weeber, and G. Eckert R.G. van der Heijde Dynamic mechanical properties of human lenses Exp. Eye Res. 80 2005 425 434 (Pubitemid 40253584)
12. R.A. Schachar, R.W. Chan, and M. Fu Viscoelastic properties of fresh human lenses under 40 years of age: implications for the aetiology of presbyopia Br. J. Ophthalmol. 95 2011 1010 1013
13. H.A. Weeber, and R.G.L. van der Heijde On the relationship between lens stiffness and accommodative amplitude Exp. Eye Res. 85 2007 602 607 (Pubitemid 47633573)
14. K.R. Heys, and R.J.W. Truscott The stiffness of human cataract lenses is a function of both age and the type of cataract Exp. Eye Res. 86 2008 701 703
15. A. Glasser Restoration of accommodation: surgical options for correction of presbyopia Clin. Exp. Optom. 91 2008 279 295
16. H.J. Burd, G.S. Wilde, and S.J. Judge An improved spinning lens test to determine the stiffness of the human lens Exp. Eye Res. 92 2011 28 39
17. R.F. Fisher The elastic constants of the human lens J. Physiol. 212 1971 147 180
18. A. Glasser, and M.C.W. Campbell Presbyopia and the optical changes in the human crystalline lens with age Vision Res. 38 1998 209 229 (Pubitemid 27503836)
19. H.A. Weeber, and G. Eckert R.G. van der Heijde Stiffness gradient in the crystalline lens Graefes Arch. Clin. Exp. Ophthalmol. 245 2007 1357 1366 (Pubitemid 47287358)
20. H. Baradia, N. Nikahd, and A. Glasser Mouse lens stiffness measurements Exp. Eye Res. 91 2010 300 307
21. T.N. Erpelding, K.W. Hollman, and M. O'Donnell Mapping age-related elasticity changes in porcine lenses using bubble-based acoustic radiation force Exp. Eye Res. 84 2007 332 341 (Pubitemid 44970458)
22. C.L. De Korte, and A.F.W. Van Der Steen G.J. Puppels Relation between local acoustic parameters and protein distribution in human and porcine eye lenses Exp. Eye Res. 59 1994 617 627 (Pubitemid 24359881)
23. G. Scarcelli, and S.H. Yun Confocal Brillouin microscopy for three-dimensional mechanical imaging Nat. Photonics. 2 2008 39 43
24. J.M. Vaughan, and J.T. Randall Brillouin scattering, density and elastic properties of the lens and cornea of the eye Nature 284 1980 489 491 (Pubitemid 10121335)
25. S.T. Bailey, and M.D. Twa R. Sooryakumar Light-scattering study of the normal human eye lens: elastic properties and age dependence IEEE Trans. Biomed. Eng. 57 2010 2910 2917
26. G. Scarcelli, P. Kim, and S.H. Yun Cross-axis cascading of spectral dispersion Opt. Lett. 33 2008 2979 2981
27. G. Scarcelli, and S.H. Yun Multistage VIPA etalons for high-extinction parallel Brillouin spectroscopy Opt. Express 19 2011 10913 10922
28. B.K. Pierscionek, A. Belaidi, and H.H. Bruun Refractive index distribution in the porcine eye lens for 532 nm and 633 nm light Eye (Lond.) 19 2005 375 381 (Pubitemid 40553135)
29. B.K. Pierscionek Refractive index of decapsulated bovine lens surfaces measured with a reflectometric sensor Vision Res. 34 1994 1927 1933
30. B.K. Pierscionek The refractive index along the optic axis of the bovine lens Eye (Lond.) 9 1995 776 782 (Pubitemid 26018206)
31. R.A. Schachar, R.W. Chan, and M. Fu Viscoelastic shear properties of the fresh porcine lens Br. J. Ophthalmol. 91 2007 366 368 (Pubitemid 46586536)
32. M.R.K. Mofrad, and R.D. Kamm Cytoskeletal Mechanics 2006 Cambridge University Press New York
33. B. Fabry, and G.N. Maksym J.J. Fredberg Scaling the microrheology of living cells Phys. Rev. Lett. 87 2001 148102
34. P. Sollich, and F. Lequeux M.E. Cates Rheology of soft glassy materials Phys. Rev. Lett. 78 1997 2020 2023 (Pubitemid 127647417)
35. F. Gittes, and F.C. MacKintosh Dynamic shear modulus of a semiflexible polymer network Phys. Rev. E Stat. Phys. Plasmas Fluids Relat. Interdiscip. Topics 58 1998 R1241 R1244
36. D. Discher, and C. Dong S. Weinbaum Biomechanics: cell research and applications for the next decade Ann. Biomed. Eng. 37 2009 847 859
37. J.F. Greenleaf, M. Fatemi, and M. Insana Selected methods for imaging elastic properties of biological tissues Annu. Rev. Biomed. Eng. 5 2003 57 78 (Pubitemid 40125308)
38. L.H. Deng, and X. Trepat J.J. Fredberg Fast and slow dynamics of the cytoskeleton Nat. Mater. 5 2006 636 640 (Pubitemid 44157681)
39. F.A. Duck Physical Properties of Tissue 1990 Academic Press London
40. S. Holm, and R. Sinkus A unifying fractional wave equation for compressional and shear waves J. Acoust. Soc. Am. 127 2010 542 559
41. S. Nishimoto, and K. Kawane S. Nagata Nuclear cataract caused by a lack of DNA degradation in the mouse eye lens Nature 424 2003 1071 1074 (Pubitemid 37064309)
42. Sistla, P. A., M. A. Reilly,..., N. Ravi. 2009. The effect of R120G mutation in αB-Crystallin on the mechanical properties of mouse lenses. Proc. ARVO Reducing Disparit. Eye Dis. Treat., Ft. Lauderdale, FL. Abstract 2107.