Membrane-associated CD93 regulates leukocyte migration and C1q-hemolytic activity during murine peritonitis

Journal of Immunology

Volumn 187, Issue 6, 2011, Pages 3353-3361

  Greenlee Wacker, Mallary C ^a   Briseño, Carlos ^a   Galvan, Manuel ^a,b   Moriel, Gabriela ^a   Velázquez, Peter ^a,b   Bohlson, Suzanne S ^a,b  

^a UNIVERSITY OF NOTRE DAME   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD93 ANTIGEN; COMPLEMENT COMPONENT C1Q; GLYCOPROTEIN; THIOGLYCOLIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHIMERA; COMPLEMENT ACTIVATION; COMPLEMENT CLASSICAL PATHWAY; CONTROLLED STUDY; EMBRYO; HEMATOPOIETIC CELL; HEMOLYSIS; HUMAN; HUMAN CELL; INFLAMMATION; LEUKOCYTE MIGRATION; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PERITONITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEPSIS; WILD TYPE;

ANIMALS; CELL MEMBRANE; CHEMOTAXIS, LEUKOCYTE; COMPLEMENT C1Q; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEK293 CELLS; HEMOLYSIS; HUMANS; IMMUNOHISTOCHEMISTRY; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PERITONITIS; RECEPTORS, COMPLEMENT; TRANSFECTION;

EID: 80053087267     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1100803     Document Type: Article

References (23)

1. Nathan, C. 2002. Points of control in inflammation. Nature 420: 846-852. (Pubitemid 36019637)
2. Coussens, L. M., and Z. Werb. 2002. Inflammation and cancer. Nature 420: 860-867. (Pubitemid 36019639)
3. Serhan, C. N., N. Chiang, and T. E. Van Dyke. 2008. Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat. Rev. Immunol. 8: 349-361. (Pubitemid 351595216)
4. Greenlee, M. C., S. A. Sullivan, and S. S. Bohlson. 2008. CD93 and related family members: their role in innate immunity. Curr. Drug Targets 9: 130-138. (Pubitemid 351461011)
5. Shi, C. S., G. Y. Shi, S. M. Hsiao, Y. C. Kao, K. L. Kuo, C. Y. Ma, C. H. Kuo, B. I. Chang, C. F. Chang, C. H. Lin, et al. 2008. Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response. Blood 112: 3661-3670.
6. Van de Wouwer, M., S. Plaisance, A. De Vriese, E. Waelkens, D. Collen, J. Persson, M. R. Daha, and E. M. Conway. 2006. The lectin-like domain of thrombomodulin interferes with complement activation and protects against arthritis. J. Thromb. Haemost. 4: 1813-1824. (Pubitemid 44144810)
7. Conway, E. M., M. Van de Wouwer, S. Pollefeyt, K. Jurk, H. Van Aken, A. De Vriese, J. I. Weitz, H. Weiler, P. W. Hellings, P. Schaeffer, et al. 2002. The lectinlike domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways. J. Exp. Med. 196: 565-577. (Pubitemid 35024436)
8. Delvaeye, M., M. Noris, A. De Vriese, C. T. Esmon, N. L. Esmon, G. Ferrell, J. Del-Favero, S. Plaisance, B. Claes, D. Lambrechts, et al. 2009. Thrombomodulin mutations in atypical hemolytic-uremic syndrome. N. Engl. J. Med. 361: 345-357.
9. Harhausen, D., V. Prinz, G. Ziegler, K. Gertz, M. Endres, H. Lehrach, P. Gasque, M. Botto, P. F. Stahel, U. Dirnagl, et al. 2010. CD93/AA4.1: a novel regulator of inflammation in murine focal cerebral ischemia. J. Immunol. 184: 6407-6417.
10. Bohlson, S. S., R. Silva, M. I. Fonseca, and A. J. Tenner. 2005. CD93 is rapidly shed from the surface of human myeloid cells and the soluble form is detected in human plasma. J. Immunol. 175: 1239-1247. (Pubitemid 41095013)
11. Greenlee, M. C., S. A. Sullivan, and S. S. Bohlson. 2009. Detection and characterization of soluble CD93 released during inflammation. Inflamm. Res. 58: 909-919.
12. Jeon, J. W., J. G. Jung, E. C. Shin, H. I. Choi, H. Y. Kim, M. L. Cho, S. W. Kim, Y. S. Jang, M. H. Sohn, J. H. Moon, et al. 2010. Soluble CD93 induces differentiation of monocytes and enhances TLR responses. J. Immunol. 185: 4921-4927.
13. Roach, T., S. Slater, M. Koval, L. White, E. D. Cahir McFarland, M. Okumura, M. Thomas, and E. Brown. 1997. CD45 regulates Src family member kinase activity associated with macrophage integrin-mediated adhesion. Curr. Biol. 7: 408-417. (Pubitemid 27274794)
14. Li, M., R. R. Ager, D. A. Fraser, N. O. Tjokro, and A. J. Tenner. 2008. Development of a humanized C1q A chain knock-in mouse: assessment of antibody independent beta-amyloid induced complement activation. Mol. Immunol. 45: 3244-3252.
15. Velázquez, P., B. Wei, M. McPherson, L. M. Mendoza, S. L. Nguyen, O. Turovskaya, M. Kronenberg, T. T. Huang, M. Schrage, L. N. Lobato, et al. 2008. Villous B cells of the small intestine are specialized for invariant NK T cell dependence. J. Immunol. 180: 4629-4638.
16. Tenner, A. J., P. H. Lesavre, and N. R. Cooper. 1981. Purification and radiolabeling of human C1q. J. Immunol. 127: 648-653. (Pubitemid 11054682)
17. Whaley, K., and J. North. 1997. Haemolytic assays for whole complement activity and individual components. In Complement: a practical approach. A.W. Dodds, and R. B. Sim, eds. Oxford University Press, Oxford, UK, p. 19-47.
18. Coligan, J. E., and S. N. Vogel. 2006. Innate immunity. Current Protocols in Immunology, Vol. 4. Richard Coico, ed. Hoboken, NJ, p. 14.1.1-14.1.3.
19. Qureshi, R., and B. A. Jakschik. 1988. The role of mast cells in thioglycollateinduced inflammation. J. Immunol. 141: 2090-2096.
20. Norsworthy, P. J., L. Fossati-Jimack, J. Cortes-Hernandez, P. R. Taylor, A. E. Bygrave, R. D. Thompson, S. Nourshargh, M. J. Walport, and M. Botto. 2004. Murine CD93 (C1qRp) contributes to the removal of apoptotic cells in vivo but is not required for C1q-mediated enhancement of phagocytosis. J. Immunol. 172: 3406-3414. (Pubitemid 38337919)
21. Binstadt, B. A., P. R. Patel, H. Alencar, P. A. Nigrovic, D. M. Lee, U. Mahmood, R.Weissleder, D. Mathis, and C. Benoist. 2006. Particularities of the vasculature can promote the organ specificity of autoimmune attack. Nat. Immunol. 7: 284-292.
22. Dunn, K., T. Sutton, and R. Sandoval. 2007. Live-animal imaging of renal function by multiphoton microscopy. In Current Protocols in Cytometry, Vol. 41. J. Paul Robinson, ed. Wiley, Hoboken, NJ, p. 12.9.1-12.9.18.
23. Mälarstig, A., A. Silveira, D. Wa° gsäter, J. Ohrvik, A. Bäcklund, A. Samnega° rd M. Khademi, M. L. Hellenius, K. Leander, T. Olsson, et al. 2011. Plasma CD93 concentration is a potential novel biomarker for coronary artery disease. J. Intern. Med.