Mutations in a dominant nef epitope of simian immunodeficiency virus diminish TCR:epitope peptide affinity but not epitope peptide:MHC class I binding

Journal of Immunology

Volumn 187, Issue 6, 2011, Pages 3300-3313

  Cale, Evan M ^a   Bazick, Heidi S ^a   Rianprakaisang, Tony A ^a   Alam, S Munir ^b   Letvin, Norman L ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NEF PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; BINDING AFFINITY; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE RESPONSE; GENE; GENE EXPRESSION; GENE SEQUENCE; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; NONHUMAN; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; TARGET CELL; TCR VBETA GENE; VIRUS MUTATION;

ANIMALS; BASE SEQUENCE; CD8-POSITIVE T-LYMPHOCYTES; EPITOPES; EPITOPES, T-LYMPHOCYTE; GENE PRODUCTS, NEF; HISTOCOMPATIBILITY ANTIGENS CLASS I; IMMUNE EVASION; IMMUNODOMINANT EPITOPES; MACACA MULATTA; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN BINDING; RECEPTORS, ANTIGEN, T-CELL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 80053068719     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1101080     Document Type: Article

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