-
1
-
-
78149406113
-
-
Owen, J. S.; Melhem, M.; Passarell, J. A.; D'Andrea, D.; Darwish, M.; Kahl, B. Cancer Chemother. Pharmacol. 2010, 66, 1039
-
(2010)
Cancer Chemother. Pharmacol.
, vol.66
, pp. 1039
-
-
Owen, J.S.1
Melhem, M.2
Passarell, J.A.3
D'Andrea, D.4
Darwish, M.5
Kahl, B.6
-
3
-
-
70350048900
-
-
Eichbaum, M.; Bischofs, E.; Nehls, K.; Schneeweiss, A.; Sohn, C. Drugs Today 2009, 45, 431
-
(2009)
Drugs Today
, vol.45
, pp. 431
-
-
Eichbaum, M.1
Bischofs, E.2
Nehls, K.3
Schneeweiss, A.4
Sohn, C.5
-
4
-
-
40749085662
-
-
Leoni, L. M.; Bailey, B.; Reifert, J.; Bendall, H. H.; Zeller, R. W.; Corbeil, J.; Elliott, G.; Niemeyer, C. C. Clin. Cancer Res. 2008, 14, 309
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 309
-
-
Leoni, L.M.1
Bailey, B.2
Reifert, J.3
Bendall, H.H.4
Zeller, R.W.5
Corbeil, J.6
Elliott, G.7
Niemeyer, C.C.8
-
5
-
-
22344452534
-
-
Teichert, J.; Sohr, R.; Bauman, F.; Hennig, L.; Merkle, K.; Caca, K.; Preiss, R. Drug Metab. Dispos. 2005, 33, 984
-
(2005)
Drug Metab. Dispos.
, vol.33
, pp. 984
-
-
Teichert, J.1
Sohr, R.2
Bauman, F.3
Hennig, L.4
Merkle, K.5
Caca, K.6
Preiss, R.7
-
6
-
-
80053021420
-
-
Gao, L.; Wang, Y.; Song, D. Chinese J. New Drugs 2007, 16, 1960
-
(2007)
Chinese J. New Drugs
, vol.16
, pp. 1960
-
-
Gao, L.1
Wang, Y.2
Song, D.3
-
8
-
-
0026114082
-
-
Werner, W.; Letsch, G.; Ihn, W.; Sohr, R.; Preiss, R. Pharmazie 1991, 46, 113
-
(1991)
Pharmazie
, vol.46
, pp. 113
-
-
Werner, W.1
Letsch, G.2
Ihn, W.3
Sohr, R.4
Preiss, R.5
-
10
-
-
0023319641
-
-
Werner, W.; Letsch, G.; Ihn, W. Pharmazie 1987, 42, 272
-
(1987)
Pharmazie
, vol.42
, pp. 272
-
-
Werner, W.1
Letsch, G.2
Ihn, W.3
-
11
-
-
80053010947
-
-
U.S. Patent Application 2010042568, April 15, 2010
-
Chen, J.; Przyuski, K.; Roemmele, R. Processes for the Preparation of Bendamustine. U.S. Patent Application 2010042568, April 15, 2010
-
Processes for the Preparation of Bendamustine
-
-
Chen, J.1
Przyuski, K.2
Roemmele, R.3
-
12
-
-
80053000540
-
-
Chem. Abstr. 2010, 152, 469331
-
(2010)
Chem. Abstr.
, vol.152
, pp. 469331
-
-
-
13
-
-
80053007283
-
-
Abstracts of Papers, 240th ACS National Meeting, Boston, MA, United States, August 22-26, 2010.
-
Chen, J.; Przyuski, K.; Roemmele, R. Abstracts of Papers, 240th ACS National Meeting, Boston, MA, United States, August 22-26, 2010; Chem. Abstr. 2010, 152, 1012421.
-
(2010)
Chem. Abstr.
, vol.152
, pp. 1012421
-
-
Chen, J.1
Przyuski, K.2
Roemmele, R.3
-
16
-
-
0842328913
-
-
Chen, B.; Zhao, R.; Bednarz, M. S.; Wang, B.; Sundeen, J. E.; Barrish, J. C. J. Org. Chem. 2004, 69, 977
-
(2004)
J. Org. Chem.
, vol.69
, pp. 977
-
-
Chen, B.1
Zhao, R.2
Bednarz, M.S.3
Wang, B.4
Sundeen, J.E.5
Barrish, J.C.6
-
17
-
-
12344311063
-
-
Yang, D.; Fokas, D.; Li, J.; Yu, L.; Baldino, C. M. Synthesis 2005, 1, 47
-
(2005)
Synthesis
, vol.1
, pp. 47
-
-
Yang, D.1
Fokas, D.2
Li, J.3
Yu, L.4
Baldino, C.M.5
-
18
-
-
71649112099
-
-
Ruiz, V. R.; Corma, A.; Sabater, M. J. Tetrahedron 2010, 66, 730
-
(2010)
Tetrahedron
, vol.66
, pp. 730
-
-
Ruiz, V.R.1
Corma, A.2
Sabater, M.J.3
-
19
-
-
2442528324
-
-
Fouad, F. S.; Xi, Z.; Goldberg, I. H.; Jones, G. B. Bioorg. Med. Chem. Lett. 2004, 14, 3337
-
(2004)
Bioorg. Med. Chem. Lett.
, vol.14
, pp. 3337
-
-
Fouad, F.S.1
Xi, Z.2
Goldberg, I.H.3
Jones, G.B.4
-
20
-
-
0001459622
-
-
Peck, R. M.; Preston, R. K.; Creech, H. J. J. Am. Chem. Soc. 1959, 81, 3984
-
(1959)
J. Am. Chem. Soc.
, vol.81
, pp. 3984
-
-
Peck, R.M.1
Preston, R.K.2
Creech, H.J.3
-
21
-
-
34250219551
-
-
Rachid, Z.; Brahimi, F.; Qiu, Q.; Williams, C.; Hartley, J. M.; Hartley, J. A.; Jean-Claude, B. J. J. Med. Chem. 2007, 50, 2605
-
(2007)
J. Med. Chem.
, vol.50
, pp. 2605
-
-
Rachid, Z.1
Brahimi, F.2
Qiu, Q.3
Williams, C.4
Hartley, J.M.5
Hartley, J.A.6
Jean-Claude, B.J.7
-
22
-
-
0038607503
-
-
Lee, H. H.; Palmer, B. D.; Boyd, M.; Denny, W. A. J. Heterocycl. Chem. 1996, 33, 1191
-
(1996)
J. Heterocycl. Chem.
, vol.33
, pp. 1191
-
-
Lee, H.H.1
Palmer, B.D.2
Boyd, M.3
Denny, W.A.4
-
23
-
-
2342519428
-
-
Niculescu-Duvaz, I.; Scanlon, I.; Niculescu-Duvaz, D.; Friedlos, F.; Martin, J.; Marais, R.; Springer, C. J. J. Med. Chem. 2004, 47, 2651
-
(2004)
J. Med. Chem.
, vol.47
, pp. 2651
-
-
Niculescu-Duvaz, I.1
Scanlon, I.2
Niculescu-Duvaz, D.3
Friedlos, F.4
Martin, J.5
Marais, R.6
Springer, C.J.7
-
24
-
-
78751644718
-
-
Lin, S.; Sun, Q.; Ge, Z.; Wang, X.; Ye, J.; Li, R. Bioorg. Med. Chem. Lett. 2011, 21, 940
-
(2011)
Bioorg. Med. Chem. Lett.
, vol.21
, pp. 940
-
-
Lin, S.1
Sun, Q.2
Ge, Z.3
Wang, X.4
Ye, J.5
Li, R.6
-
25
-
-
0025021102
-
-
Palmer, B. D.; Wilson, W. R.; Pullen, S. M.; Denny, W. A. J. Med. Chem. 1990, 33, 112
-
(1990)
J. Med. Chem.
, vol.33
, pp. 112
-
-
Palmer, B.D.1
Wilson, W.R.2
Pullen, S.M.3
Denny, W.A.4
-
26
-
-
0842326737
-
-
Ferlin, M. G.; Via, L. D.; Gia, O. M. Bioorg. Med. Chem. 2004, 12, 771
-
(2004)
Bioorg. Med. Chem.
, vol.12
, pp. 771
-
-
Ferlin, M.G.1
Via, L.D.2
Gia, O.M.3
-
27
-
-
23444457117
-
-
Davies, L. C.; Friedlos, F.; Hedley, D.; Martin, J.; Ogilvie, L. M.; Scalon, I. J.; Springer, C. J. J. Med. Chem. 2005, 48, 5321
-
(2005)
J. Med. Chem.
, vol.48
, pp. 5321
-
-
Davies, L.C.1
Friedlos, F.2
Hedley, D.3
Martin, J.4
Ogilvie, L.M.5
Scalon, I.J.6
Springer, C.J.7
-
28
-
-
3042793405
-
-
Delfourne, E.; Kiss, R.; Le Corre, L.; Dujols, F.; Bastide, J.; Collignon, F.; Lesur, B.; Frydman, A.; Darro, F. Bioorg. Med. Chem. 2004, 12, 3987
-
(2004)
Bioorg. Med. Chem.
, vol.12
, pp. 3987
-
-
Delfourne, E.1
Kiss, R.2
Le Corre, L.3
Dujols, F.4
Bastide, J.5
Collignon, F.6
Lesur, B.7
Frydman, A.8
Darro, F.9
-
29
-
-
0037103341
-
-
Delfourne, E.; Darro, F.; Portefaix, P.; Galaup, C.; Bayssade, S.; Bouteillé, A.; Le Corre, L.; Bastide, J.; Collignon, F.; Lesur, B.; Frydman, A.; Kiss, R. J. Med. Chem. 2002, 45, 3765
-
(2002)
J. Med. Chem.
, vol.45
, pp. 3765
-
-
Delfourne, E.1
Darro, F.2
Portefaix, P.3
Galaup, C.4
Bayssade, S.5
Bouteillé, A.6
Le Corre, L.7
Bastide, J.8
Collignon, F.9
Lesur, B.10
Frydman, A.11
Kiss, R.12
-
30
-
-
22744433849
-
-
Palani, A.; Shapiro, S.; McBriar, M. D.; Clader, J. W.; Greenlee, W. J.; Spar, B.; Kowalski, T. J.; Farley, C.; Cook, J.; Heek, M.; Weig, B.; O'Neill, K.; Graziano, M.; Hawes, B. J. Med. Chem. 2005, 48, 4746
-
(2005)
J. Med. Chem.
, vol.48
, pp. 4746
-
-
Palani, A.1
Shapiro, S.2
McBriar, M.D.3
Clader, J.W.4
Greenlee, W.J.5
Spar, B.6
Kowalski, T.J.7
Farley, C.8
Cook, J.9
Heek, M.10
Weig, B.11
O'Neill, K.12
Graziano, M.13
Hawes, B.14
-
31
-
-
4043071644
-
-
Borch, R. F.; Bernstein, M. D.; Durst, H. D. J. Am. Chem. Soc. 1971, 93, 2897
-
(1971)
J. Am. Chem. Soc.
, vol.93
, pp. 2897
-
-
Borch, R.F.1
Bernstein, M.D.2
Durst, H.D.3
-
33
-
-
0001100460
-
-
Lumsden, M. D.; Wasylishen, R. E.; Eichele, I.; Schindler, M.; Penner, G. H.; Power, W. P.; Curtis, R. D. J. Am. Chem. Soc. 1994, 116, 1403
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 1403
-
-
Lumsden, M.D.1
Wasylishen, R.E.2
Eichele, I.3
Schindler, M.4
Penner, G.H.5
Power, W.P.6
Curtis, R.D.7
-
34
-
-
0000984934
-
-
Yamada, K.; Dong, S.; Wu, G. J. Am. Chem. Soc. 2000, 122, 11602
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 11602
-
-
Yamada, K.1
Dong, S.2
Wu, G.3
-
35
-
-
84986492398
-
-
Okuwaki, Y.; Inagawa, Y.; Tamamura, H.; Suzuki, T.; Kuwana, H.; Tahara, M.; Yuasa, K.; Ohta, A. J. Heterocycl. Chem. 1987, 24, 187
-
(1987)
J. Heterocycl. Chem.
, vol.24
, pp. 187
-
-
Okuwaki, Y.1
Inagawa, Y.2
Tamamura, H.3
Suzuki, T.4
Kuwana, H.5
Tahara, M.6
Yuasa, K.7
Ohta, A.8
-
38
-
-
66249099869
-
-
Van Alsten, J. G.; Jorgensen, M. L.; am Ende, D. J. Org. Process Res. Dev. 2009, 13, 629
-
(2009)
Org. Process Res. Dev.
, vol.13
, pp. 629
-
-
Van Alsten, J.G.1
Jorgensen, M.L.2
Am Ende, D.J.3
-
39
-
-
0346638131
-
-
Hoogenraad, M.; van der Linden, J. B.; Smith, A. A.; Hughes, B.; Derrick, A. M.; Harris, L. J.; Higginson, P. D.; Pettman, A. J. Org. Process Res. Dev. 2004, 8, 469
-
(2004)
Org. Process Res. Dev.
, vol.8
, pp. 469
-
-
Hoogenraad, M.1
Van Der Linden, J.B.2
Smith, A.A.3
Hughes, B.4
Derrick, A.M.5
Harris, L.J.6
Higginson, P.D.7
Pettman, A.J.8
-
40
-
-
0029682583
-
-
Berkman, C. E.; Underiner, G. E.; Cashman, J. R. J. Org. Chem. 1996, 61, 5686
-
(1996)
J. Org. Chem.
, vol.61
, pp. 5686
-
-
Berkman, C.E.1
Underiner, G.E.2
Cashman, J.R.3
-
41
-
-
0037424292
-
-
Shieh, W.; Dell, S.; Bach, A.; Repič, O.; Blacklock, T. J. J. Org. Chem. 2003, 68, 1954
-
(2003)
J. Org. Chem.
, vol.68
, pp. 1954
-
-
Shieh, W.1
Dell, S.2
Bach, A.3
Repič, O.4
Blacklock, T.J.5
-
42
-
-
0034366344
-
-
Hasanm, M.; Shaheen, F.; Yunas, U. Turk. J. Chem. 2000, 24, 73
-
(2000)
Turk. J. Chem.
, vol.24
, pp. 73
-
-
Hasanm, M.1
Shaheen, F.2
Yunas, U.3
-
43
-
-
33750129787
-
-
Magnus, N. A.; Staszak, M. A.; Udodong, U. E.; Wepsiec, J. P. Org. Process Res. Dev. 2006, 10, 899
-
(2006)
Org. Process Res. Dev.
, vol.10
, pp. 899
-
-
Magnus, N.A.1
Staszak, M.A.2
Udodong, U.E.3
Wepsiec, J.P.4
-
44
-
-
33644767061
-
-
Chiappe, C.; Piccioli, P.; Pieraccini, D. Green Chem. 2006, 8, 277
-
(2006)
Green Chem.
, vol.8
, pp. 277
-
-
Chiappe, C.1
Piccioli, P.2
Pieraccini, D.3
-
45
-
-
37049087585
-
-
Katritzky, A. R.; Drewniak, M.; Aurrecoechea, J. M. J. Chem. Soc. 1987, 1, 2539
-
(1987)
J. Chem. Soc.
, vol.1
, pp. 2539
-
-
Katritzky, A.R.1
Drewniak, M.2
Aurrecoechea, J.M.3
-
46
-
-
0038003837
-
-
Prashad, M.; Har, D.; Hu, B.; Kim, H.; Repic, O.; Blacklock, T. J. Org. Lett. 2003, 5, 125
-
(2003)
Org. Lett.
, vol.5
, pp. 125
-
-
Prashad, M.1
Har, D.2
Hu, B.3
Kim, H.4
Repic, O.5
Blacklock, T.J.6
-
47
-
-
80052989497
-
-
Cephalon, Inc. Frazer, PA, Unpublished work.
-
Landmesser, N. Cephalon, Inc., Frazer, PA, Unpublished work, 2009.
-
(2009)
-
-
Landmesser, N.1
-
48
-
-
0000844109
-
-
Abdel-Magid, A. F.; Carson, K. G.; Harris, B. D.; Maryanoff, C. A.; Shah., R. D. J. Org. Chem. 1996, 61, 3849
-
(1996)
J. Org. Chem.
, vol.61
, pp. 3849
-
-
Abdel-Magid, A.F.1
Carson, K.G.2
Harris, B.D.3
Maryanoff, C.A.4
Shah, R.D.5
-
50
-
-
12344289276
-
-
Lam, T. L.; Bagner, C.; Tuma, L. Thermochim. Acta 2005, 426, 109
-
(2005)
Thermochim. Acta
, vol.426
, pp. 109
-
-
Lam, T.L.1
Bagner, C.2
Tuma, L.3
-
51
-
-
0000408711
-
-
Gribble, G. W.; Lord, P. D.; Skotnicki, J.; Dietz, S. E.; Eaton, J. T.; Johnson, J. J. Am. Chem. Soc. 1974, 96, 7812
-
(1974)
J. Am. Chem. Soc.
, vol.96
, pp. 7812
-
-
Gribble, G.W.1
Lord, P.D.2
Skotnicki, J.3
Dietz, S.E.4
Eaton, J.T.5
Johnson, J.6
-
54
-
-
0000473171
-
-
Marchini, P.; Liso, G.; Reho, A.; Liberatore, F.; Moracci, F. M. J. Org. Chem. 1975, 40, 3453
-
(1975)
J. Org. Chem.
, vol.40
, pp. 3453
-
-
Marchini, P.1
Liso, G.2
Reho, A.3
Liberatore, F.4
Moracci, F.M.5
|