Synthesis of an immunogenic template for the generation of catalytic antibodies for (-)-cocaine hydrolysis

Journal of Organic Chemistry

Volumn 61, Issue 16, 1996, Pages 5686-5689

  Berkman, Clifford E ^a   Underiner, Gail E ^a   Cashman, John R ^a  

^a SEATTLE BIOMEDICAL RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYTIC ANTIBODY; COCAINE;

ARTICLE; DRUG HYDROLYSIS; IMMUNOGENICITY;

EID: 0029682583     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo960522q     Document Type: Article

References (10)

1. Landry, D. W.; Zhao, K.; Yang, G. X. Q.; Glickman, M.; Georgiadis, T. M. Science 1993, 259, 1899.
2. Rocio, M.; Carrera, A.; Ashley, J. A.; Parsons, L. H.; Wirsching, P.; Koob, G. F.; Janda, K. D. Nature 1995, 378, 727.
3. Brzezinski, M. R.; Abraham, T. L.; Stone, C. L.; Dean, R. A.; Bosron, W. F. Biochem. Phamacol. 1994, 48, 1747.
4. Kozikowski, A. P.; Xiang, L.; Tanaka, J.; Bergmann, J. S.; Johnson, K. M. Med. Chem. Res. 1991, 1, 312.
5. Lewin, A. H.; Gao, Y.; Abraham, P.; Boja, J. W.; Kuhar, M. J.; Carroll, F. I. J. Med. Chem. 1992, 35, 135.
6. Hernandez, A. S; Thaler, A.; Castells, J.; Rapoport, H. J. Org. Chem. 1996, 61, 314.
7. Kozikowski, A.; Saiah, M. K. E.; Johnson, K. M.; Bergmann, J. S. J. Med. Chem. 1995, 38, 3086.
8. Zhao, K.; Landry, D. W. Tetrahedron Lett. 1993, 49, 363.
9. Jackson, A. G.; Kenner, G. W.; Moore, G. A.; Ramage, R.; Thorpe, W. D. Tetrahedron Lett. 1976, 40, 3627.
10. Mckenna, C. E.; Schmidhauser, J. J. Chem. Soc., Chem. Commun. 1979, 739.