Pharmacologic suppression of hepatic ATP-binding cassette transporter 1 activity in mice reduces high-density lipoprotein cholesterol levels but promotes reverse cholesterol transport

Circulation

Volumn 124, Issue 12, 2011, Pages 1382-1390

  Yamamoto, Shigenori ^a   Tanigawa, Hiroyuki ^a   Li, Xiaoyu ^a   Komaru, Yohei ^a   Billheimer, Jeffrey T ^a,b   Rader, Daniel J ^a,b,c  

^a Institute for Translational Medicine and Therapeutics   (United States)

^b Cardiovascular Institute   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

atherosclerosis; cholesterol, HDL; lipids; lipoproteins; pharmacology

Indexed keywords

ABC TRANSPORTER A1; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; PROBUCOL; SCAVENGER RECEPTOR BI;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DRUG EFFECT; DRUG INDICATION; DRUG MECHANISM; KNOCKOUT MOUSE; LIVER; LIVER CELL; MACROPHAGE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTICHOLESTEREMIC AGENTS; ATHEROSCLEROSIS; ATP-BINDING CASSETTE TRANSPORTERS; BILIARY TRACT; BIOLOGICAL TRANSPORT; CELLS, CULTURED; CHOLESTEROL, HDL; DISEASE MODELS, ANIMAL; HEPATOCYTES; HUMANS; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; MICE, KNOCKOUT; PROBUCOL; XANTHOMATOSIS;

EID: 80052969415     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.110.009704     Document Type: Article

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