Determination of ionization constants of N-imidazole derivatives, aromatase inhibitors, using capillary electrophoresis and influence of substituents on pKa shifts

Journal of Chromatography A

Volumn 1035, Issue 1, 2004, Pages 131-136

  Foulon, C ^a   Danel, C ^a   Vaccher, C ^a   Yous, S ^a   Bonte, J P ^a   Goossens, J F ^a  

^a UNIV LILLE   (France)

Author keywords

Benzothiazolinones; Benzoxazolinones; Dissociation constants; Enzyme inhibitors; Imidazoles; Ionization constants

Indexed keywords

CAPILLARITY; CHEMICAL MODIFICATION; ELECTROPHORESIS; IONIZATION; ULTRAVIOLET SPECTROSCOPY;

CHIRAL SELECTORS; IONIZATION CONSTANTS;

AROMATIC COMPOUNDS;

ANASTROZOLE; AROMATASE INHIBITOR; FADROZOLE; IMIDAZOLE DERIVATIVE; LETROZOLE; VOROZOLE;

ACIDITY; ARTICLE; CAPILLARY ELECTROPHORESIS; ENANTIOSELECTIVITY; ION TRANSPORT; IONIZATION; MATHEMATICAL COMPUTING; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; ULTRAVIOLET SPECTROSCOPY; VALIDATION PROCESS;

AROMATASE INHIBITORS; BUFFERS; ENZYME INHIBITORS; HYDROGEN-ION CONCENTRATION; IMIDAZOLES; IONS; OSMOSIS; REPRODUCIBILITY OF RESULTS;

EID: 1842450928     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2004.02.053     Document Type: Article

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