Homeobox gene Distal-less 3 (DLX3) is a regulator of villous cytotrophoblast differentiation

Placenta

Volumn 32, Issue 10, 2011, Pages 745-751

  Chui, A ^a,b   Evseenko, D A ^c   Brennecke, S P ^a,b   Keelan, J A ^d   Kalionis, B ^a,b   Murthi, P ^a,b  

^a ROYAL WOMEN'S HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

DLX3; Function; Homeobox; Placenta

Indexed keywords

FORSKOLIN; MESSENGER RNA;

ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL LINE; CONTROLLED STUDY; CYTOTROPHOBLAST; DISTAL-LESS 3 GENE; DNA FLANKING REGION; FEMALE; GENE ACTIVITY; GENE EXPRESSION; GENE FUNCTION; HOMEOBOX; HUMAN; HUMAN CELL; PLACENTA; PLACENTA DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUPERNATANT; TROPHOBLAST;

3-HYDROXYSTEROID DEHYDROGENASES; CELL DIFFERENTIATION; CELL LINE; FEMALE; GENE PRODUCTS, ENV; HOMEODOMAIN PROTEINS; HUMANS; IMMUNOBLOTTING; PLACENTA; PREGNANCY; PREGNANCY PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STATISTICS, NONPARAMETRIC; TRANSCRIPTION FACTORS; TROPHOBLASTS;

EID: 80052950304     PISSN: 01434004     EISSN: 15323102     Source Type: Journal    
DOI: 10.1016/j.placenta.2011.07.007     Document Type: Article

References (35)

1. J. Stulc Extracellular transport pathways in the haemochorial placenta Placenta 10 1 1989 113 119 (Pubitemid 19113480)
2. M. Knofler, L. Saleh, S. Bauer, B. Galos, H. Rotheneder, and P. Husslein Transcriptional regulation of the human chorionic gonadotropin beta gene during villous trophoblast differentiation Endocrinology 145 4 2004 1685 1694 (Pubitemid 38402376)
3. L. Peng, J. Arensburg, J. Orly, and A.H. Payne The murine 3beta-hydroxysteroid dehydrogenase (3beta-HSD) gene family: a postulated role for 3beta-HSD VI during early pregnancy Mol Cell Endocrinol 187 1-2 2002 213 221 (Pubitemid 34436951)
4. A.J. Potgens, S. Drewlo, M. Kokozidou, and P. Kaufmann Syncytin: the major regulator of trophoblast fusion? Recent developments and hypotheses on its action Hum Reprod Update 10 6 2004 487 496 (Pubitemid 39529881)
5. D.W. Morrish, D. Bhardwaj, L.K. Dabbagh, H. Marusyk, and O. Siy Epidermal growth factor induces differentiation and secretion of human chorionic gonadotropin and placental lactogen in normal human placenta J Clin Endocrinol Metab 65 6 1987 1282 1290 (Pubitemid 18026872)
6. D.W. Morrish, V. Manickavel, L.D. Jewell, and O. Siy Immunolocalization of alpha and beta chains of human chorionic gonadotropin, placental lactogen and pregnancy-specific beta-glycoprotein in term placenta by a touch preparation method Histochemistry 88 1 1987 57 60 (Pubitemid 18012387)
7. D.W. Morrish, H. Marusyk, and O. Siy Demonstration of specific secretory granules for human chorionic gonadotropin in placenta J Histochem Cytochem 35 1 1987 93 101 (Pubitemid 17221602)
8. I.P. Crocker, B.K. Strachan, G.E. Lash, S. Cooper, A.Y. Warren, and P.N. Baker Vascular endothelial growth factor but not placental growth factor promotes trophoblast syncytialization in vitro J Soc Gynecol Investig 8 6 2001 341 346 (Pubitemid 34031763)
9. S. Black, M. Kadyrov, P. Kaufmann, B. Ugele, N. Emans, and B. Huppertz Syncytial fusion of human trophoblast depends on caspase 8 Cell Death Differ 11 1 2004 90 98 (Pubitemid 38111376)
10. D. Baczyk, S. Drewlo, L. Proctor, C. Dunk, S. Lye, and J. Kingdom Glial cell missing-1 transcription factor is required for the differentiation of the human trophoblast Cell Death Differ 16 5 2009 719 727
11. H. Rehder, and U. Friedrich Molecular approaches to developmental genetics and pathology Am J Med Genet Suppl 3 1987 15 22
12. W.J. Gehring, Y.Q. Qian, M. Billeter, K. Furukubo-Tokunaga, A.F. Schier, and D. Resendez-Perez Homeodomain-DNA recognition Cell 78 2 1994 211 223 (Pubitemid 24241090)
13. W.J. Gehring, M. Muller, M. Affolter, A. Percival-Smith, M. Billeter, and Y.Q. Qian The structure of the homeodomain and its functional implications Trends Genet 6 10 1990 323 329
14. K. Chawengsaksophak, W. de Graaff, J. Rossant, J. Deschamps, and F. Beck Cdx2 is essential for axial elongation in mouse development Proc Natl Acad Sci U S A 101 20 2004 7641 7645 (Pubitemid 38658082)
15. Y. Li, and R.R. Behringer Esx1 is an X-chromosome-imprinted regulator of placental development and fetal growth Nat Genet 20 3 1998 309 311 (Pubitemid 28507681)
16. J. van Nes, W. de Graaff, F. Lebrin, M. Gerhard, F. Beck, and J. Deschamps The Cdx4 mutation affects axial development and reveals an essential role of Cdx genes in the ontogenesis of the placental labyrinth in mice Development 133 3 2006 419 428 (Pubitemid 43273828)
17. M.I. Morasso, N.G. Markova, and T.D. Sargent Regulation of epidermal differentiation by a Distal-less homeodomain gene J Cell Biol 135 6 Pt 2 1996 1879 1887 (Pubitemid 27036448)
18. A.J. Bendall, and C. Abate-Shen Roles for Msx and Dlx homeoproteins in vertebrate development Gene 247 1-2 2000 17 31 (Pubitemid 30201557)
19. S.A. Anderson, D.D. Eisenstat, L. Shi, and J.L. Rubenstein Interneuron migration from basal forebrain to neocortex: dependence on Dlx genes Science 278 5337 1997 474 476 (Pubitemid 27454433)
20. G. Panganiban, and J.L. Rubenstein Developmental functions of the Distal-less/Dlx homeobox genes Development 129 19 2002 4371 4386 (Pubitemid 35203722)
21. J.C. Cross How to make a placenta: mechanisms of trophoblast cell differentiation in mice-a review Placenta 26 Suppl. A 2005 S3 S9
22. M.I. Morasso, A. Grinberg, G. Robinson, T.D. Sargent, and K.A. Mahon Placental failure in mice lacking the homeobox gene Dlx3 Proc Natl Acad Sci U S A 96 1 1999 162 167 (Pubitemid 29036070)
23. L. Peng, and A.H. Payne AP-2 gamma and the homeodomain protein distal-less 3 are required for placental-specific expression of the murine 3 beta-hydroxysteroid dehydrogenase VI gene, Hsd3b6 J Biol Chem 277 10 2002 7945 7954 (Pubitemid 34968245)
24. K.A. Berghorn, P.A. Clark, B. Encarnacion, C.J. Deregis, J.K. Folger, and M.I. Morasso Developmental expression of the homeobox protein Distal-less 3 and its relationship to progesterone production in mouse placenta J Endocrinol 186 2 2005 315 323 (Pubitemid 41167400)
25. L. Peng, Y. Huang, F. Jin, S.W. Jiang, and A.H. Payne Transcription enhancer factor-5 and a GATA-like protein determine placental-specific expression of the Type I human 3beta-hydroxysteroid dehydrogenase gene, HSD3B1 Mol Endocrinol 18 8 2004 2049 2060 (Pubitemid 39006508)
26. M.S. Roberson, S. Meermann, M.I. Morasso, J.M. Mulvaney-Musa, and T. Zhang A role for the homeobox protein Distal-less 3 in the activation of the glycoprotein hormone alpha subunit gene in choriocarcinoma cells J Biol Chem 276 13 2001 10016 10024
27. A. Chui, N.A. Pathirage, B. Johnson, M. Cocquebert, T. Fournier, and D. Evain-Brion Homeobox gene distal-less 3 is expressed in proliferating and differentiating cells of the human placenta Placenta 31 8 2010 691 697
28. D.A. Evseenko, J.W. Paxton, and J.A. Keelan The xenobiotic transporter ABCG2 plays a novel role in differentiation of trophoblast-like BeWo cells Placenta 28 Suppl. A 2007 S116 S120
29. K.E. Green, C. Thota, G.D. Hankins, C. Yallampalli, and Y.L. Dong Calcitonin gene-related peptide stimulates human villous trophoblast cell differentiation in vitro Mol Hum Reprod 12 7 2006 443 450 (Pubitemid 44288203)
30. D.A. Evseenko, J.W. Paxton, and J.A. Keelan Independent regulation of apical and basolateral drug transporter expression and function in placental trophoblasts by cytokines, steroids, and growth factors Drug Metab Dispos 35 4 2007 595 601 (Pubitemid 46513262)
31. P. Murthi, V. Doherty, J. Said, S. Donath, S.P. Brennecke, and B. Kalionis Homeobox gene HLX1 expression is decreased in idiopathic human fetal growth restriction Am J Pathol 168 2 2006 511 518 (Pubitemid 43271149)
32. P. Murthi, J.M. Said, V.L. Doherty, S. Donath, C.J. Nowell, and S.P. Brennecke Homeobox gene DLX4 expression is increased in idiopathic human fetal growth restriction Mol Hum Reprod 12 12 2006 763 769 (Pubitemid 44811655)
33. K.J. Livak, and T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method Methods 25 4 2001 402 408 (Pubitemid 34164012)
34. M. Ruebner, P.L. Strissel, M. Langbein, F. Fahlbusch, D.L. Wachter, and F. Faschingbauer Impaired cell fusion and differentiation in placentae from patients with intrauterine growth restriction correlate with reduced levels of HERV envelope genes J Mol Med 88 11 2010 1143 1156
35. B. Huppertz, H.G. Frank, J.C. Kingdom, F. Reister, and P. Kaufmann Villous cytotrophoblast regulation of the syncytial apoptotic cascade in the human placenta Histochem Cell Biol 110 5 1998 495 508 (Pubitemid 28480282)