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Volumn 46, Issue 9, 2011, Pages 4702-4708
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Synthesis, molecular modeling and biological evaluation of chalcone thiosemicarbazide derivatives as novel anticancer agents
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Author keywords
Antiproliferative; Chalcone; EGFR; Thiosemicarbazide
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Indexed keywords
2 ( 3 PHENYL 1 4 TOLYLALLYLIDENE)HYDRAZINECARBOTHIOAMIDE;
2 (1 PHENYL 3 4 TOLYLALLYLIDENE)HYDRAZINECARBOTHIOAMIDE;
2 (1,3 DIPHENYLALLYLIDENE)HYDRAZINECARBOTHIOAMIDE;
2 (3 (2 BROMOPHENYL) 1 PHENYLALLYLIDENE)HYDRAZINECARBOTHIOAMIDE;
2 [1 (3,4 DICHLOROPHENYL) 3 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [1 (4 BROMOPHENYL) 3 (4 FLUOROPHENYL)ALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [1 (4 BROMOPHENYL) 3 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [1 (4 CHLOROPHENYL) 3 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [1 (4 METHOXYPHENYL) 3 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [3 (2 CHLOROPHENYL) 1 (4 METHOXYPHENYL)ALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [3 (2 CHLOROPHENYL) 1 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [3 (2 FLUOROPHENYL) 1 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [3 (2 METHOXYPHENYL) 1 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [3 (3 FLUOROPHENYL) 1 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [3 (3 METHOXYPHENYL) 1 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [3 (3 NITROPHENYL) 1 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [3 (4 BROMOPHENYL) 1 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [3 (4 CHLOROPHENYL) 1 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [3 (4 FLUOROPHENYL) 1 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [3 (4 METHOXYPHENYL) 1 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [3 (4 NITROPHENYL) 1 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [3 (BIPHENYL 4 YL) 1 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [3 (NAPHTHALEN 1 YL) 1 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
2 [3 [4 (BENZYLOXY)PHENYL] 1 PHENYLALLYLIDENE]HYDRAZINECARBOTHIOAMIDE;
ANTINEOPLASTIC AGENT;
CHALCONE DERIVATIVE;
EPIDERMAL GROWTH FACTOR RECEPTOR KINASE INHIBITOR;
THIOSEMICARBAZIDE DERIVATIVE;
UNCLASSIFIED DRUG;
ANTINEOPLASTIC ACTIVITY;
APOPTOSIS;
ARTICLE;
BIOLOGICAL ACTIVITY;
CANCER GROWTH;
CANCER INHIBITION;
CONTROLLED STUDY;
DRUG BINDING;
DRUG DESIGN;
DRUG STRUCTURE;
DRUG SYNTHESIS;
HEPATOMA CELL;
HUMAN;
HUMAN CELL;
IC 50;
MOLECULAR DOCKING;
STRUCTURE ACTIVITY RELATION;
ANTINEOPLASTIC AGENTS;
APOPTOSIS;
CELL LINE, TUMOR;
CHALCONES;
CRYSTALLOGRAPHY, X-RAY;
HUMANS;
MAGNETIC RESONANCE SPECTROSCOPY;
RECEPTOR, EPIDERMAL GROWTH FACTOR;
SEMICARBAZIDES;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
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EID: 80052948424
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2011.07.016 Document Type: Article |
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Times cited : (109)
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References (23)
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