Cytotoxic copper (II) mixed ligand complexes: Crystal structure and DNA cleavage activity

European Journal of Medicinal Chemistry

Volumn 46, Issue 9, 2011, Pages 4537-4547

  Manikandamathavan, Verasuntharam M ^a   Parameswari, Royapuram P ^c   Weyhermüller, Thomas ^b   Vasanthi, Hannah R ^c   Nair, Balachandran Unni ^a  

^a CENTRAL LEATHER RESEARCH INSTITUTE   (India)

^b MAX PLANCK INSTITUTE FOR CHEMICAL ENERGY CONVERSION   (Germany)

^c SRI RAMACHANDRA UNIVERSITY   (India)

Author keywords

Copper (II) mixed ligand complex; Cytotoxcity; Intercelator; Metallo nucleases; Terpyridine

Indexed keywords

ANTINEOPLASTIC AGENT; COPPER COMPLEX;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DNA BINDING; DNA CLEAVAGE; DRUG STRUCTURE; HYDROGEN BOND; HYDROLYSIS; IN VITRO STUDY; LUNG ADENOCARCINOMA;

APOPTOSIS; CELL LINE, TUMOR; COPPER; CRYSTALLOGRAPHY, X-RAY; DNA; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; HUMANS; HYDROLYSIS; LIGANDS; MODELS, MOLECULAR; SPECTROMETRY, FLUORESCENCE;

EID: 80052933594     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.07.030     Document Type: Article

References (51)

1. P.B. Dervan Bioorg. Med. Chem. 9 2001 2215 2235
2. M.J. Hannon Chem. Soc. Rev. 36 2007 280 295
3. R. Martinez, and G.L. Chacon Curr. Med. Chem. 12 2005 127 151
4. J. Reedijk Chem. Commun. 1996 801 806
5. B. Lippert Cisplatin: Chemistry and Biochemistry of a Leading Anticancer Drug 1999 Wiley-VCH Weinheim, Germany
6. A. Marin-Hernandez, I. Gracia Mora, L. Ruiz-Ramirez, and R. Moreno Sanchez Biochem. Pharmacol. 65 2003 1979 1989
7. Y. Uno, and M. Morita Mutat. Res. Genet. Toxicol. 298 1993 269 275
8. T. Gebel, H. Lantzsch, K. Plessow, and H. Dunkelberg Mutat. Res. Genet. Toxicol. Environ. Mutagen 389 1997 183 190
9. S.M. Cohen, and S.J. Lippard Prog. Nucleic Acid Res. Mol. Biol. 67 2001 93 130
10. A. Arbuse, C. Anda, M.A. Martinez, J. PerezMiron, C. Jaime, T. Parella, and A. Llobet Inorg. Chem. 46 2007 10632 10638
11. T. Chao, S. Ying, G. Ning, X. Qiang, and G. Zijian Inorg. Chem. 43 2004 4761 4766
12. C. Jingwen, W. Xiaoyong, S. Ying, Z. Jianhui, Z. Yangguang, L. Yizhi, X. Qiang, and G. Zijian Inorg. Chem. 46 2007 3306 3312
13. K.E. Erkilla, D.T. Odom, and J.K. Barton Chem. Rev. 99 1999 2777 2795
14. T. Gupta, S. Dhar, M. Nethaji, and A.R. Chakravarty Dalton Tran. 2004 1896 1900
15. A. Arounaguiry, and B.G. Maiya Inorg. Chem. 39 2000 4256 4263
16. V.M. Manikandamathavan, M. Kavitha, V. Uma, R.P. Parameswari, H.R. Vasanthi, and B.U. Nair Polyhedron 30 2011 1604 1611
17. S. Arounaguiri, and B.G. Maiya Inorg. Chem. 35 1996 4267 4270
18. D.S. Sigman, A. Mazumder, and D.M. Perrin Chem. Rev. 93 1993 2295 2316
19. D.S. Sigman Acc. Chem. Res. 19 1986 180 186
20. K.A. Reich, L.E. Marshall, D.R. Graham, and D.S. Sigman J. Am. Chem. Soc. 103 1981 3582 3584
21. E. Kovari, and R. Kramer Chem. Ber. 127 1994 2151 2157
22. E. Kovari, J. Heitker, and R. Kramer J. Chem. Soc. Chem. Commun. 1995 1205 1206
23. E. Kovari, and R. Kramer J. Am. Chem. Soc. 118 1996 12704 12709
24. V.G. Vaidyanathan, T. Weyhermuller, B.U. Nair, and J. Subramanian J. Inorg. Biochem. 99 2005 2248 2255
25. V. Uma, M. Elango, and B.U. Nair Eur. J. Inorg. Chem. 2007 3484 3490
26. V. Uma, A. Castineiras, and B.U. Nair Polyhedron 26 2007 3008 3016
27. R. Indumathy, M. Kanthimathi, T. Weyhermuller, and B.U. Nair Polyhedron 27 2008 3443 3450
28. G. Sathyaraj, T. Weyhermuller, and B.U. Nair Eur. J. Med. Chem. 45 2010 284 291
29. K. Nakamoto Infrared and Raman Spectra of Inorganic and Coordination Compounds 1986 Wiley New York 243
30. A.A. Schilt, and R.C. Taylor J. Inorg. Nucl. Chem. 9 1959 211 221
31. C. Furlani Coord. Chem. Rev. 3 1968 141 167
32. G. Ondrejovic, A. Kotocova, and D. valigura Chem. Pap. 56 2002 168 173
33. J. Zemann Z. Anorg. Allg. Chem. 324 1963 241 249
34. M.J. Belousoff, L. Tjioe, B. Graham, and L. Spiccia Inorg. Chemistry 47 2008 8641 8651
35. S. Cudzilo, W. Trzcinski, M. Nita, S. Michalik, S. Krompiec, R. Kruszynski, and J. Kusz Propellants Explos. Pyrotech 36 2011 151 159
36. J. Mcginley, V. Mckee, H. Toftlund, and J.M.D. Walsh Dalton Trans. 2009 8406 8412
37. V. Uma, M. Kanthimathi, T. Weyhermuller, and B.U. Nair J. Inorg. Bio. Chem. 99 2005 2299 2307
38. J.K. Barton, J.M. Goldberg, C.V. Kumar, and N.J. Turro J. Am. Chem. Soc. 108 1986 2081 2088
39. J.M. Kelly, A.B. Tossi, D.J. McConnell, and C. Ohuigin Nucleic Acids Res. 13 1985 6017 6034
40. S.J. Martin, C.P. Reutelingsperger, A.J. McGahon, J.A. Rader, R.C. van-Schie, D.M. Laface, and D.R. Green Abl. J. Exp. Med. 182 1995 1545 1556
41. J.C. Kern, and J.P. Kehrer Chem.-Bio. Int. 139 2002 79 95
42. S.V. Lennon, S.J. Martin, and T.G. Cotter Cell Prolif. 24 1991 203 214
43. M.J. Gomkex-Lechon, E.O. Connor, J.V. Castell, and R. Jover Toxicological Sci. 65 2002 299 308
44. G.W.V. Cave, and C.L. Raston J. Chem. Soc. Perkin Trans. I 2001 3258 3264
45. J. Murmur J. Mol. Biol. 3 1961 208 218
46. M.F. Reichmann, S.A. Rice, C.A. Thomas, and P. Doty J. Am. Chem. Soc. 76 1954 3047 3053
47. ShelXtl V. 5 1994 Siemens Analytical X-Ray Instruments, Inc.
48. ShelXL97, and G.M. Sheldrick 1997 University of Gottingen
49. F.F. Safadi, J. Xu, S.L. Smock, R.A. Kanaan, A.H. Selim, P.R. Odgren, S.C. Marks Jr., T.A. Owen, and S.N. Popoff J. Cell. Physiol. 196 2003 51 62
50. G. Haslam, D. Wyatt, and P.A. Kitos Cytotechnology 32 2000 63 75
51. H.T. Wolterbeek, and A.J. vander meer Assay Drug Dev. Technol. 3 2005 675 682