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Volumn 18, Issue 7, 2011, Pages 478-484

Folate-conjugated methoxy poly (ethylene glycol)/poly (L-Alanine) amphiphilic block copolymeric micelles for targeted delivery of paclitaxel

Author keywords

Amphiphilic block copolymer; folate; micelles; paclitaxel; targeted delivery

Indexed keywords

COPOLYMER; FOLIC ACID; FOLIC ACID METHOXY POLY (ETHYLENE GLYCOL) CONJUGATE; FOLIC ACID POLY(ALANINE) CONJUGATE; PACLITAXEL; UNCLASSIFIED DRUG;

EID: 80052930019     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2011.589086     Document Type: Article
Times cited : (17)

References (41)
  • 1
    • 54949100738 scopus 로고    scopus 로고
    • DNA block copolymer micelles -A combinatorial tool for cancer Nanotechnology
    • ALEMDAROGLU, F. E., ALEMDAROGLU, N. C., LANGGUTH, P. & HERRMANN, A. (2008) DNA block copolymer micelles -A combinatorial tool for cancer Nanotechnology. Advanced Materials. 20:899-902.
    • (2008) Advanced Materials , vol.20 , pp. 899-902
    • Alemdaroglu, F.E.1    Alemdaroglu, N.C.2    Langguth, P.3    Herrmann, A.4
  • 3
    • 0038246506 scopus 로고    scopus 로고
    • Folate-targeted PEG as a potential carrier for carboplatin analogs. Synthesis and in vitro studies
    • DOI 10.1021/bc025642l
    • ARONOV, O., HOROWITZ, A. T., GABIZON, A. & GIBSON, D. (2003) Folate-targeted PEG as a potential carrier for carboplatin analogs. Synthesis and in vitro studies. Bioconjugate Chemistry. 14:563-574. (Pubitemid 36597366)
    • (2003) Bioconjugate Chemistry , vol.14 , Issue.3 , pp. 563-574
    • Aronov, O.1    Horowitz, A.T.2    Gabizon, A.3    Gibson, D.4
  • 4
    • 29244463596 scopus 로고    scopus 로고
    • Folate-mediated targeting of polymeric conjugates of gemcitabine
    • DOI 10.1016/j.ijpharm.2005.10.015, PII S0378517305006721
    • CAVALLARO, G., MARIANO, L., SALMASO, S., CALICETI, P. & GAETANO, G. (2006) Folate-mediated targeting of polymeric conjugates of gemcitabine. International Journal of Pharmaceutics. 307:258-269. (Pubitemid 41820423)
    • (2006) International Journal of Pharmaceutics , vol.307 , Issue.2 , pp. 258-269
    • Cavallaro, G.1    Mariano, L.2    Salmaso, S.3    Caliceti, P.4    Gaetano, G.5
  • 5
    • 55049115208 scopus 로고    scopus 로고
    • Functionalized amphiphilic hyperbranched polymers for targeted drug delivery
    • CHEN, S., ZHANG, X. Z., CHENG, S. X., ZHUO, R. X. & GU, Z. W. (2008) Functionalized Amphiphilic Hyperbranched Polymers for Targeted Drug Delivery. Biomacromolecules. 9:2578-2585.
    • (2008) Biomacromolecules , vol.9 , pp. 2578-2585
    • Chen, S.1    Zhang, X.Z.2    Cheng, S.X.3    Zhuo, R.X.4    Z, W.G.U.5
  • 6
    • 62749159930 scopus 로고    scopus 로고
    • Morphology and in vitro release kinetics of drug-loaded micelles based on well-defined PMPC-b-PBMA copolymer
    • CHU, H. Y., LIU, N., WANG, X., JIAO, Z. & CHEN, Z. M. (2009) Morphology and in vitro release kinetics of drug-loaded micelles based on well-defined PMPC-b-PBMA copolymer. International Journal of Pharmaceutics. 371:190-196.
    • (2009) International Journal of Pharmaceutics , vol.371 , pp. 190-196
    • Chu, H.Y.1    Liu, N.2    Wang, X.3    Jiao, Z.4    Chen, Z.M.5
  • 7
    • 41949105734 scopus 로고    scopus 로고
    • Folate-conjugated thermoresponsive block copolymers: Highly efficient conjugation and solution self-assembly
    • DOI 10.1021/bm701255v
    • DE, P., GONDI, S. R. & SUMERLIN, B. S. (2008) Folate-conjugated thermoresponsive block copolymers: Highly efficient conjugation and solution self-assembly. Biomacromolecules. 9:1064-1070. (Pubitemid 351560503)
    • (2008) Biomacromolecules , vol.9 , Issue.3 , pp. 1064-1070
    • De, P.1    Gondi, S.R.2    Sumerlin, B.S.3
  • 8
    • 1942439013 scopus 로고    scopus 로고
    • Tumor cell targeting of liposome-entrapped drugs with phospholipid-anchored folic acid-PEG conjugates
    • DOI 10.1016/j.addr.2004.01.011, PII S0169409X04000201
    • GABIZON, A., SHMEEDA, H., HOROWITZ, A. T. & ZALIPSKY, S. (2004) Tumor cell targeting of liposome-entrapped drugs with phospholipid-anchored folic acid-PEG conjugates. Advanced Drug Delivery Reviews. 56:1177-1192. (Pubitemid 38496514)
    • (2004) Advanced Drug Delivery Reviews , vol.56 , Issue.8 , pp. 1177-1192
    • Gabizon, A.1    Shmeeda, H.2    Horowitz, A.T.3    Zalipsky, S.4
  • 9
    • 64149104210 scopus 로고    scopus 로고
    • 9-NC-loaded folate-conjugated polymer micelles as tumor targeted drug delivery system: Preparation and evaluation in vitro
    • HAN, X., LIU, J., LIU, M., XIE, C., ZHAN, C. Y., GU, B., LIU, Y., FENG, L. L. & LU, W. Y. (2009) 9-NC-loaded folate-conjugated polymer micelles as tumor targeted drug delivery system: Preparation and evaluation in vitro. International Journal of Pharmaceutics. 372:125-131.
    • (2009) International Journal of Pharmaceutics , vol.372 , pp. 125-131
    • Han, X.1    Liu, J.2    Liu, M.3    Xie, C.4    Zhan, C.Y.5    U, B.G.6    Liu, Y.7    Feng, L.L.8    W, Y.L.U.9
  • 11
    • 34547903625 scopus 로고    scopus 로고
    • The characterization of paclitaxel-loaded microspheres manufactured from blends of poly(lactic-co-glycolic acid) (PLGA) and low molecular weight diblock copolymers
    • DOI 10.1016/j.ijpharm.2007.04.022, PII S0378517307003389
    • JACKSON, J. K., HUNG, T., LETCHFORD, K. & BURT, H. M. (2007) The characterization of paclitaxel-loaded microspheres manufactured from blends of poly(lactic-co-glycolic acid) (PLGA) and low molecular weight diblock copolymers. International Journal of Pharmaceutics. 342:6-17. (Pubitemid 47259315)
    • (2007) International Journal of Pharmaceutics , vol.342 , Issue.1-2 , pp. 6-17
    • Jackson, J.K.1    Hung, T.2    Letchford, K.3    Burt, H.M.4
  • 12
    • 0347224284 scopus 로고    scopus 로고
    • The folate receptor as a molecular target for tumor-selective radionuclide delivery
    • DOI 10.1016/S0969-8051(03)00117-3
    • KE, C. Y., MATHIAS, C. J. & GREEN, M. A. (2003) The folate receptor as a molecular target for tumor-selective radionuclide delivery. Nuclear Medicine and Biology. 30:811-817. (Pubitemid 38040989)
    • (2003) Nuclear Medicine and Biology , vol.30 , Issue.8 , pp. 811-817
    • Ke, C.-Y.1    Mathias, C.J.2    Green, M.A.3
  • 14
    • 55849090997 scopus 로고    scopus 로고
    • Doxorubicin-Loaded Polymeric Micelle Overcomes Multidrug Resistance of Cancer by Double-Targeting Folate Receptor and Early Endosomal pH
    • KIM, D., LEE, E. S., OH, K. T., GAO, Z. G. & BAE, Y. H. (2008) Doxorubicin-Loaded Polymeric Micelle Overcomes Multidrug Resistance of Cancer by Double-Targeting Folate Receptor and Early Endosomal pH. Small. 4:2043-2050.
    • (2008) Small , vol.4 , pp. 2043-2050
    • Kim, D.1    Lee, E.S.2    K, T.O.H.3    Gao, Z.G.4    Bae, Y.H.5
  • 15
    • 34548409638 scopus 로고    scopus 로고
    • Receptor-mediated gene delivery by folate-PEG-baculovirus in vitro
    • DOI 10.1016/j.jbiotec.2007.07.938, PII S0168165607013156
    • KIM, Y. K., CHOI, J. Y., YOO, M. K., JIANG, H. L., AROTE, R., JE, Y. H., CHO, M. H. & CHO, C. S. (2007) Receptor-mediated gene delivery by folate-PEG-baculovirus in vitro. Journal of Biotechnology. 131:353-361. (Pubitemid 47362433)
    • (2007) Journal of Biotechnology , vol.131 , Issue.3 , pp. 353-361
    • Kim, Y.-K.1    Choi, J.Y.2    Yoo, M.-K.3    Jiang, H.-L.4    Arote, R.5    Je, Y.H.6    Cho, M.-H.7    Cho, C.-S.8
  • 16
    • 0141921483 scopus 로고    scopus 로고
    • Polymeric micelle for tumor pH and folate-mediated targeting
    • DOI 10.1016/S0168-3659(03)00239-6
    • LEE, E. S., NA, K. & BAE, Y. H. (2003) Polymeric micelle for tumor pH and folate-mediated targeting. Journal of Controlled Release. 91:103-113. (Pubitemid 37288881)
    • (2003) Journal of Controlled Release , vol.91 , Issue.1-2 , pp. 103-113
    • Lee, E.S.1    Na, K.2    Bae, Y.H.3
  • 17
    • 0036242840 scopus 로고    scopus 로고
    • Synthesis and evaluation of Taxol-folic acid conjugates as targeted antineoplastics
    • DOI 10.1016/S0968-0896(02)00019-6, PII S0968089602000196
    • LEE, J. W., LU, J. Y., LOW, P. S. & FUCHS, P. L. (2002) Synthesis and evaluation of taxol-folic acid conjugates as targeted antineoplastics. Bioorganic & Medicinal Chemistry. 10:2397-2414. (Pubitemid 34450929)
    • (2002) Bioorganic and Medicinal Chemistry , vol.10 , Issue.7 , pp. 2397-2414
    • Lee, J.W.1    Lu, J.Y.2    Low, P.S.3    Fuchs, P.L.4
  • 19
    • 2942612987 scopus 로고    scopus 로고
    • Membrane transporter/receptor-targeted prodrug design: Strategies for human and veterinary drug development
    • DOI 10.1016/j.addr.2004.02.006, PII S0169409X04000699, Veterinary Drug Delivery: Part VI
    • MAJUMDAR, S., DUVVURI, S. & MITRA, A. K. (2004) Membrane transporter/receptor-targeted prodrug design: strategies for human and veterinary drug development. Advanced Drug Delivery Reviews. 56:1437-1452. (Pubitemid 38748825)
    • (2004) Advanced Drug Delivery Reviews , vol.56 , Issue.10 , pp. 1437-1452
    • Majumdar, S.1    Duvvuri, S.2    Mitra, A.K.3
  • 21
    • 0022858683 scopus 로고
    • A new concept for macromolecular therapeutics in cancer chemotherapy: Mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
    • MATSUMURA, Y. & MAEDA, H. (1986) A New Concept for Macromolecular Therapeutics in Cancer-Chemotherapy -Mechanism of Tumoritropic Accumulation of Proteins and the Antitumor Agent Smancs. Cancer Research. 46:6387-6392. (Pubitemid 17221789)
    • (1986) Cancer Research , vol.46 , Issue.12 , pp. 6387-6392
    • Matsumura, Y.1    Maeda, H.2
  • 22
    • 0037314879 scopus 로고    scopus 로고
    • Self-assembled nanoparticles of hydrophobically-modified polysaccharide bearing vitamin H as a targeted anti-cancer drug delivery system
    • DOI 10.1016/S0928-0987(02)00257-9
    • NA, K., LEE, T. B., PARK, K. H., SHIN, E. K., LEE, Y. B. & CHO, H. K. (2003) Self-assembled nanoparticles of hydrophobically-modified polysaccharide bearing vitamin H as a targeted anti-cancer drug delivery system. European Journal of Pharmaceutical Sciences. 18:165-173. (Pubitemid 36184755)
    • (2003) European Journal of Pharmaceutical Sciences , vol.18 , Issue.2 , pp. 165-173
    • Na, K.1    Lee, T.B.2    Park, K.-H.3    Shin, E.-K.4    Lee, Y.-B.5    Choi, H.-K.6
  • 23
    • 41949133558 scopus 로고    scopus 로고
    • Targeted delivery of paclitaxel using folate-decorated poly(lactide) -vitamin e TPGS nanoparticles
    • PAN, J. & FENG, S. S. (2008) Targeted delivery of paclitaxel using folate-decorated poly(lactide) -vitamin E TPGS nanoparticles. Biomaterials. 29:2663-2672.
    • (2008) Biomaterials , vol.29 , pp. 2663-2672
    • Pan, J.1    Feng, S.S.2
  • 24
    • 28444473061 scopus 로고    scopus 로고
    • Folate-conjugated methoxy poly(ethylene glycol)/poly(ε-caprolactone) amphiphilic block copolymeric micelles for tumor-targeted drug delivery
    • DOI 10.1016/j.jconrel.2005.09.039, PII S016836590500489X
    • PARK, E. K., KIM, S. Y., LEE, S. B. & LEE, Y. M. (2005) Folateconjugated methoxy poly(ethylene glycol)/poly(epsiloncaprolactone) amphiphilic block copolymeric micelles for tumor-targeted drug delivery. Journal of Controlled Release. 109:158-168. (Pubitemid 41737262)
    • (2005) Journal of Controlled Release , vol.109 , Issue.1-3 , pp. 158-168
    • Park, E.K.1    Kim, S.Y.2    Lee, S.B.3    Lee, Y.M.4
  • 25
    • 0347005967 scopus 로고
    • New, easily removable poly(Ethylene glycol) supports for the liquid-phase method of peptide-synthesis
    • PILLAI, V. N. R., MUTTER, M., BAYER, E. & GATFIELD, I. (1980) New, Easily Removable Poly(Ethylene Glycol) Supports for the Liquid-Phase Method of Peptide-Synthesis. Journal of Organic Chemistry. 45:5364-5370.
    • (1980) Journal of Organic Chemistry , vol.45 , pp. 5364-5370
    • Pillai, V.N.R.1    Mutter, M.2    Bayer, E.3    Gatfield, I.4
  • 26
    • 0036889760 scopus 로고    scopus 로고
    • Targeted drug delivery via the transferrin receptor-mediated endocytosis pathway
    • DOI 10.1124/pr.54.4.561
    • QIAN, Z. M., LI, H. Y., SUN, H. Z. & HO, K. (2002) Targeted drug delivery via the transferrin receptor-mediated endocytosis pathway. Pharmacological Reviews. 54:561-587. (Pubitemid 35351196)
    • (2002) Pharmacological Reviews , vol.54 , Issue.4 , pp. 561-587
    • Qian, Z.M.1    Li, H.2    Sun, H.3    Ho, K.4
  • 27
    • 34547561267 scopus 로고    scopus 로고
    • Physical stimuli-responsive polymeric micelles for anti-cancer drug delivery
    • DOI 10.1016/j.progpolymsci.2007.05.009, PII S0079670007000640, Polymers in Biomedical Applications
    • RAPOPORT, N. (2007) Physical stimuli-responsive polymeric micelles for anti-cancer drug delivery. Progress in Polymer Science. 32:962-990. (Pubitemid 47198285)
    • (2007) Progress in Polymer Science (Oxford) , vol.32 , Issue.8-9 , pp. 962-990
    • Rapoport, N.1
  • 28
    • 5344270492 scopus 로고    scopus 로고
    • Vitamin-mediated targeting as a potential mechanism to increase drug uptake by tumours
    • DOI 10.1016/j.jinorgbio.2004.07.009, PII S0162013404002028
    • RUSSELL-JONES, G., MCTAVISH, K., MCEWAN, J., RICE, J. & NOWOTNIK, D. (2004) Vitamin-mediated targeting as a potential mechanism to increase drug uptake by tumours. Journal of Inorganic Biochemistry. 98:1625-1633. (Pubitemid 39349188)
    • (2004) Journal of Inorganic Biochemistry , vol.98 , Issue.10 SPEC. ISS. , pp. 1625-1633
    • Russell-Jones, G.1    McTavish, K.2    McEwan, J.3    Rice, J.4    Nowotnik, D.5
  • 29
    • 0038797831 scopus 로고    scopus 로고
    • Ligand-targeted liposomal anticancer drugs
    • DOI 10.1016/S0163-7827(03)00032-8
    • SAPRA, P. & ALLEN, T. M. (2003) Ligand-targeted liposomal anticancer drugs. Progress in Lipid Research. 42:439-462. (Pubitemid 36700404)
    • (2003) Progress in Lipid Research , vol.42 , Issue.5 , pp. 439-462
    • Sapra, P.1    Allen, T.M.2
  • 30
    • 44149103399 scopus 로고    scopus 로고
    • Design and synthesis of releasable folate-drug conjugates using a novel heterobifunctional disulfide-containing linker
    • DOI 10.1016/j.bmcl.2008.04.063, PII S0960894X08004678
    • SATYAM, A. (2008) Design and synthesis of releasable folate-drug conjugates using a novel heterobifunctional disulfide-containing linker. Bioorganic & Medicinal Chemistry Letters. 18:3196-3199. (Pubitemid 351718341)
    • (2008) Bioorganic and Medicinal Chemistry Letters , vol.18 , Issue.11 , pp. 3196-3199
    • Satyam, A.1
  • 31
    • 0037161316 scopus 로고    scopus 로고
    • Efficient intracellular drug and gene delivery using folate receptor-targeted pH-sensitive liposomes composed of cationic/anionic lipid combinations
    • DOI 10.1016/S0168-3659(02)00017-2, PII S0168365902000172
    • SHI, G. F., GUO, W. J., STEPHENSON, S. M. & LEE, R. J. (2002) Efficient intracellular drug and gene delivery using folate receptor-targeted pH-sensitive liposomes composed of cationic/anionic lipid combinations. Journal of Controlled Release. 80:309-319. (Pubitemid 34273768)
    • (2002) Journal of Controlled Release , vol.80 , Issue.1-3 , pp. 309-319
    • Shi, G.1    Guo, W.2    Stephenson, S.M.3    Lee, R.J.4
  • 32
    • 0343882023 scopus 로고    scopus 로고
    • Targeted drug delivery via the folate receptor
    • DOI 10.1016/S0169-409X(99)00062-9, PII S0169409X99000629
    • SUDIMACK, J. & LEE, R. J. (2000) Targeted drug delivery via the folate receptor. Advanced Drug Delivery Reviews. 41:147-162. (Pubitemid 30122955)
    • (2000) Advanced Drug Delivery Reviews , vol.41 , Issue.2 , pp. 147-162
    • Sudimack, J.1    Lee, R.J.2
  • 33
    • 34447093841 scopus 로고    scopus 로고
    • Design, synthesis, and biological activity of folate receptor-targeted prodrugs of thiolate histone deacetylase inhibitors
    • DOI 10.1016/j.bmcl.2007.05.040, PII S0960894X07005938
    • SUZUKI, T., HISAKAWA, S., ITOH, Y., SUZUKI, N., TAKAHASHI, K., KAWAHATA, M., YAMAGUCHI, K., NAKAGAWA, H. & MIYATA, N. (2007) Design, synthesis, and biological activity of folate receptortargeted prodrugs of thiolate histone deacetylase inhibitors. Bioorganic & Medicinal Chemistry Letters. 17:4208-4212. (Pubitemid 47028601)
    • (2007) Bioorganic and Medicinal Chemistry Letters , vol.17 , Issue.15 , pp. 4208-4212
    • Suzuki, T.1    Hisakawa, S.2    Itoh, Y.3    Suzuki, N.4    Takahashi, K.5    Kawahata, M.6    Yamaguchi, K.7    Nakagawa, H.8    Miyata, N.9
  • 34
    • 36849012080 scopus 로고    scopus 로고
    • Self-assembled thermosensitive micelles based on Poly(L-lactide
    • star block-N-isopropylacrylamide) for drug delivery
    • WEI, H., ZHANG, X. Z., CHEN, W. Q., CHENG, S. X. & ZHUO, R. X. (2007) Self-assembled thermosensitive micelles based on Poly(L-lactide-star block-N-isopropylacrylamide) for drug delivery. Journal of Biomedical Materials Research Part A, 83A, 980-989.
    • (2007) Journal of Biomedical Materials Research Part A , vol.83 , pp. 980-989
    • Wei, H.1    Zhang, X.Z.2    Chen, W.Q.3    Cheng, S.X.4    Zhuo, R.X.5
  • 35
    • 33646894333 scopus 로고    scopus 로고
    • A folate receptor-targeted liposomal formulation for paclitaxel
    • DOI 10.1016/j.ijpharm.2006.02.027, PII S0378517306001505
    • WU, J., LIU, Q. & LEE, R. J. (2006) A folate receptor-targeted liposomal formulation for paclitaxel. International Journal of Pharmaceutics. 316:148-153. (Pubitemid 43786219)
    • (2006) International Journal of Pharmaceutics , vol.316 , Issue.1-2 , pp. 148-153
    • Wu, J.1    Liu, Q.2    Lee, R.J.3
  • 37
    • 11144293514 scopus 로고    scopus 로고
    • In vitro and in vivo evaluation of actively targetable nanoparticles for paclitaxel delivery
    • DOI 10.1016/j.ijpharm.2004.10.009, PII S0378517304006210
    • XU, Z. H., GU, W. W., HUANG, J., SUI, H., ZHOU, Z. H., YANG, Y. X., YAN, Z. & LI, Y. P. (2005) In vitro and in vivo evaluation of actively targetable nanoparticles for paclitaxel delivery. International Journal of Pharmaceutics. 288:361-368. (Pubitemid 40038589)
    • (2005) International Journal of Pharmaceutics , vol.288 , Issue.2 , pp. 361-368
    • Xu, Z.1    Gu, W.2    Huang, J.3    Sui, H.4    Zhou, Z.5    Yang, Y.6    Yan, Z.7    Li, Y.8
  • 38
    • 47149117199 scopus 로고    scopus 로고
    • Folate-encoded and Fe3O4-loaded polymeric micelles for dual targeting of cancer cells
    • YANG, X. Q., CHEN, Y. H., YUAN, R. X., CHEN, G. H., BLANCO, E., GAO, J. M. & SHUAI, X. T. (2008) Folate-encoded and Fe3O4-loaded polymeric micelles for dual targeting of cancer cells. Polymer. 49:3477-3485.
    • (2008) Polymer , vol.49 , pp. 3477-3485
    • Yang, X.Q.1    Chen, Y.H.2    Yuan, R.X.3    Chen, G.H.4    Blanco, E.5    Gao, J.M.6    Shuai, X.T.7
  • 40
    • 4143081572 scopus 로고    scopus 로고
    • Pteroyl-γ-glutamate-cysteine synthesis and its application in folate receptor-mediated cancer cell targeting using folate-tethered liposomes
    • DOI 10.1016/j.ab.2004.05.034, PII S0003269704004531
    • ZHANG, Y. H., GUO, L. L., ROESKE, R. W., ANTONY, A. C. & JAYARAM, H. N. (2004) Pteroyl-gamma-glutamate-cysteine synthesis and its application in folate receptor-mediated cancer cell targeting using folate-tethered liposomes. Analytical Biochemistry. 332:168-177. (Pubitemid 39099484)
    • (2004) Analytical Biochemistry , vol.332 , Issue.1 , pp. 168-177
    • Zhang, Y.1    Guo, L.2    Roeske, R.W.3    Antony, A.C.4    Jayaram, H.N.5
  • 41
    • 37349053715 scopus 로고    scopus 로고
    • Selectivity of folate conjugated polymer micelles against different tumor cells
    • DOI 10.1016/j.ijpharm.2007.07.040, PII S0378517307006564
    • ZHAO, H. Z. & YUNG, L. Y. L. (2008) Selectivity of folate conjugated polymer micelles against different tumor cells. International Journal of Pharmaceutics. 349:256-268. (Pubitemid 350299702)
    • (2008) International Journal of Pharmaceutics , vol.349 , Issue.1-2 , pp. 256-268
    • Zhao, H.1    Yung, L.Y.L.2


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