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Volumn 46, Issue 9, 2011, Pages 4184-4191
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Targeting the human malaria parasite Plasmodium falciparum: In vitro identification of a new antiplasmodial hit in 4-phenoxy-2- trichloromethylquinazoline series
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Author keywords
Malaria; Phenoxquinazolines; Plasmodium falciparum; Trichloromethyl group
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Indexed keywords
2 TRICHLOROMETHYL 4 [2 (TRIFLUOROMETHYL)PHENOXY]QUINAZOLINE;
2 TRICHLOROMETHYL 4 [3 (TRIFLUOROMETHYL)PHENOXY]QUINAZOLINE;
2 TRICHLOROMETHYL 4 [4 (TRIFLUOROMETHYL)PHENOXY]QUINAZOLINE;
4 (2 CHLOROPHENOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 (2 FLUOROPHENOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 (2 METHOXYPHENOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 (2 METHYLPHENOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 (2 NITROPHENOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 (3 CHLOROPHENOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 (3 FLUOROPHENOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 (3 METHOXYPHENOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 (3 METHYLPHENOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 (3 NITROPHENOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 (3,4 DIMETHYLPHENOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 (4 CHLOROPHENOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 (4 FLUOROPHENOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 (4 METHOXYPHENOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 (4 METHYLPHENOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 (4 NITROPHENOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 (NAPHTHALEN 1 YLOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 (NAPHTHALEN 2 YLOXY) 2 TRICHLOROMETHYLQUINAZOLINE;
4 CHLORO 2 TRICHLOROMETHYLQUINAZOLINE;
4 HYDROXY 2 TRICHLOROMETHYLQUINAZOLINE;
4 PHENOXY 2 TRICHLOROMETHYLQUINAZOLINE;
ANTIMALARIAL AGENT;
CHLOROQUINE;
DOXORUBICIN;
DOXYCYCLINE;
QUINAZOLINE DERIVATIVE;
UNCLASSIFIED DRUG;
UNINDEXED DRUG;
ANTIPROTOZOAL ACTIVITY;
ARTICLE;
CELL STRAIN HEPG2;
CONTROLLED STUDY;
CYTOTOXICITY;
DRUG IDENTIFICATION;
DRUG SYNTHESIS;
DRUG TARGETING;
HUMAN;
HUMAN CELL;
IC 50;
IN VITRO STUDY;
MALARIA;
NONHUMAN;
PLASMODIUM FALCIPARUM;
STRUCTURE ACTIVITY RELATION;
TOXOPLASMA;
ANIMALS;
ANTIMALARIALS;
CELL LINE;
HUMANS;
INHIBITORY CONCENTRATION 50;
MAGNETIC RESONANCE SPECTROSCOPY;
PLASMODIUM FALCIPARUM;
QUINAZOLINES;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 80052926545
PISSN: 02235234
EISSN: 17683254
Source Type: Journal
DOI: 10.1016/j.ejmech.2011.06.021 Document Type: Article |
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Times cited : (29)
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References (24)
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