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Volumn 184, Issue 6, 2011, Pages 637-641

Matrix elastin: A promising biomarker for chronic obstructive pulmonary disease

Author keywords

Biomarkers; COPD; Desmosine; Elastin; Isodesmosine

Indexed keywords

ALPHA 1 ANTICHYMOTRYPSIN; ALPHA 1 ANTITRYPSIN; ALPHA 2 MACROGLOBULIN; C REACTIVE PROTEIN; DESMOSINE; ELASTASE; ELASTIN; FIBRINOGEN; INTERLEUKIN 6; INTERLEUKIN 8; ISODESMOSINE; MATRIX PROTEIN; PEPTIDE; PROTEINASE; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR;

EID: 80052923746     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201103-0450PP     Document Type: Review
Times cited : (49)

References (65)
  • 1
    • 34548222188 scopus 로고    scopus 로고
    • Global burden of COPD: risk factors, prevalence, and future trends
    • DOI 10.1016/S0140-6736(07)61380-4, PII S0140673607613804
    • Mannino DM, Buist AS. Global burden of COPD: risk factors, prevalence and future trends. Lancet 2007;370:765-773. (Pubitemid 47321908)
    • (2007) Lancet , vol.370 , Issue.9589 , pp. 765-773
    • Mannino, D.M.1    Buist, A.S.2
  • 4
    • 0018885920 scopus 로고
    • Continuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease: A clinical trial
    • Nocturnal Oxygen Therapy Trial Group
    • Nocturnal Oxygen Therapy Trial Group. Continuous or nocturnal oxygen therapy in hypoxemic chronic obstructive lung disease: a clinical trial. Ann Intern Med 1980;93:391-398.
    • (1980) Ann Intern Med , vol.93 , pp. 391-398
  • 7
    • 24644492301 scopus 로고    scopus 로고
    • Prevention of exacerbation of chronic obstructive lung disease with tiotropium, a once daily inhaled anticholinergic bronchodilator
    • Niewoehner DE, Rice K, Cote C, Paulson D, Cooper JA Jr, Korducki L, Cassino C, Kesten S. Prevention of exacerbation of chronic obstructive lung disease with tiotropium, a once daily inhaled anticholinergic bronchodilator. Ann Intern Med 2005;143:317-326.
    • (2005) Ann Intern Med , vol.143 , pp. 317-326
    • Niewoehner, D.E.1    Rice, K.2    Cote, C.3    Paulson, D.4    Cooper Jr., J.A.5    Korducki, L.6    Cassino, C.7    Kesten, S.8
  • 9
    • 0033603794 scopus 로고    scopus 로고
    • Users' guides to the medical literature: XIX. Applying clinical trial results. A. How to use an article measuring the effect of an intervention on surrogate end points: Evidence-based medicine working group
    • Bucher HC, Guyatt GH, Cook DJ, Holbrook A, McAlister FA. Users' guides to the medical literature: XIX. Applying clinical trial results. A. How to use an article measuring the effect of an intervention on surrogate end points: evidence-based medicine working group. JAMA 1999;282:771-778.
    • (1999) JAMA , vol.282 , pp. 771-778
    • Bucher, H.C.1    Guyatt, G.H.2    Cook, D.J.3    Holbrook, A.4    McAlister, F.A.5
  • 10
    • 79954623980 scopus 로고    scopus 로고
    • US Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER) [accessed April 14, 2009]. Available from
    • US Department of Health and Human Services Food and Drug Administration Center for Drug Evaluation and Research (CDER). Guidance for industry chronic obstructive pulmonary disease: developing drugs for treatment. 2007 [accessed April 14, 2009]. Available from: http://www.fda.gov/CDER/GUIDANCE/7875dft.pdf
    • (2007) Guidance for Industry Chronic Obstructive Pulmonary Disease: Developing Drugs for Treatment
  • 11
    • 0001326524 scopus 로고    scopus 로고
    • Elastin fibers in the lung
    • Crystal RG, West JB, Weibel ER, Barnes PJ editors. Philadelphia: Lippincott- Raven
    • Mecham RP. Elastin fibers in the lung. In Crystal RG, West JB, Weibel ER, Barnes PJ editors. Scientific foundations. Philadelphia: Lippincott- Raven; 1997. pp:729-736.
    • (1997) Scientific Foundations , pp. 729-736
    • Mecham, R.P.1
  • 12
    • 0019491077 scopus 로고
    • Elastin structure, biosynthesis, and relation to disease states
    • Sandberg LB, Soskel NT, Leslie JG. Elastin structure, biosynthesis, and relation to disease states. N Engl J Med 1981;304:566-579.
    • (1981) N Engl J Med , vol.304 , pp. 566-579
    • Sandberg, L.B.1    Soskel, N.T.2    Leslie, J.G.3
  • 13
    • 0000522901 scopus 로고
    • Elastic tissue of normal and emphysematous lungs - A tridimensional histologic study
    • Wright RR. Elastic tissue of normal and emphysematous lungs - a tridimensional histologic study. Am J Pathol 1961;39:355-367.
    • (1961) Am J Pathol , vol.39 , pp. 355-367
    • Wright, R.R.1
  • 14
    • 0025163596 scopus 로고
    • The regulation of lung elastin synthesis
    • Foster JA, Curtiss SW. The regulation of lung elastin synthesis. Am J Physiol 1990;259:L23.
    • (1990) Am J Physiol , vol.259
    • Foster, J.A.1    Curtiss, S.W.2
  • 15
    • 1842464817 scopus 로고
    • The interstitium of the lung
    • Schraufnagel DE, editor. New York: Marcel Dekker
    • Kuhn C III, Oldmixon EH. The interstitium of the lung. In Schraufnagel DE, editor. Electron microscopy of the lung. New York: Marcel Dekker; 1990. pp.177-214.
    • (1990) Electron Microscopy of the Lung , pp. 177-214
    • Kuhn III, C.1    Oldmixon, E.H.2
  • 16
    • 0025780051 scopus 로고
    • Marked longevity of human lung parenchymal elastic fibers deduced fromprevalence of D-aspartate and nuclear weapons-related radiocarbon
    • Shapiro SD, Endicott SK, Province MA, Pierce JA, Campbell EJ. Marked longevity of human lung parenchymal elastic fibers deduced fromprevalence of D-aspartate and nuclear weapons-related radiocarbon. J Clin Invest 1991;87:1828-1834.
    • (1991) J Clin Invest , vol.87 , pp. 1828-1834
    • Shapiro, S.D.1    Endicott, S.K.2    Province, M.A.3    Pierce, J.A.4    Campbell, E.J.5
  • 20
    • 0018852010 scopus 로고
    • Elastin content of normal and emphysematous lung parenchyma
    • DOI 10.1016/0002-9343(80)90004-2
    • Chrzanowski P, Keller S, Cerreta J, Mandl I, Turino GM. Elastin content of normal and emphysematous lung parenchyma. Am J Med 1980;69:351-359. (Pubitemid 10059680)
    • (1980) American Journal of Medicine , vol.69 , Issue.3 , pp. 351-359
    • Chrzanowski, P.1    Keller, S.2    Cerreta, J.3
  • 21
    • 84907041622 scopus 로고
    • The electrophoretic alpha-1-globulin pattern of serum in alpha-1-antitrypsin deficiency
    • Laurell C-B, Eriksson S. The electrophoretic alpha-1-globulin pattern of serum in alpha-1-antitrypsin deficiency. Scand J Clin Lab Invest 1963;15:132-140.
    • (1963) Scand J Clin Lab Invest , vol.15 , pp. 132-140
    • Laurell, C.-B.1    Eriksson, S.2
  • 22
    • 0023795389 scopus 로고
    • Clinical features and history of the destructive lung disease associated with alpha-1-antitrypsin deficiency of adults with pulmonary symptoms
    • Brantly MS, Paul LD, Miller BH, Falk RT, Wu M, Crystal RG. Clinical features and history of the destructive lung disease associated with alpha-1-antitrypsin deficiency of adults with pulmonary symptoms. Am Rev Respir Dis 1988;138:327-336.
    • (1988) Am Rev Respir Dis , vol.138 , pp. 327-336
    • Brantly, M.S.1    Paul, L.D.2    Miller, B.H.3    Falk, R.T.4    Wu, M.5    Crystal, R.G.6
  • 23
    • 0022628541 scopus 로고
    • Elastinolytic activity of human cathepsin L
    • Mason RW, Johnson DA, Barrett AJ, Chapman HA. Elastinolytic activity of human cathepsin L. Biochem J 1986;233:925-927. (Pubitemid 16116171)
    • (1986) Biochemical Journal , vol.233 , Issue.3 , pp. 925-927
    • Mason, R.W.1    Johnson, D.A.2    Barrett, A.J.3
  • 24
    • 0002669303 scopus 로고
    • Proteinases and matrix degradation
    • Kelley WN, Harris ED, Ruddy S, Sledge CB, editors. 3rd ed. Philadelphia: W.B. Saunders
    • Werbe Z. Proteinases and matrix degradation. In: Kelley WN, Harris ED, Ruddy S, Sledge CB, editors. Textbook of rheumatology, 3rd ed. Philadelphia: W.B. Saunders; 1989. pp. 300-321.
    • (1989) Textbook of Rheumatology , pp. 300-321
    • Werbe, Z.1
  • 26
    • 0026630108 scopus 로고
    • Molecular cloning and expression of human alveolar -macrophage cathepsin S, an elastinolytic cysteine protease
    • Shi GP, Munger JS, Meara JP, Rich DH, Chapman HA. Molecular cloning and expression of human alveolar -macrophage cathepsin S, an elastinolytic cysteine protease. J Biol Chem 1992;267:7258-7262.
    • (1992) J Biol Chem , vol.267 , pp. 7258-7262
    • Shi, G.P.1    Munger, J.S.2    Meara, J.P.3    Rich, D.H.4    Chapman, H.A.5
  • 27
    • 0019160540 scopus 로고
    • Degradation of connective tissue matrices by macrophages. III. Morphological and biochemical studies on extracellular, pericellular, and intracellular events in matrix proteolysis by macrophages in culture
    • DOI 10.1084/jem.152.6.1537
    • Werb Z, Bainton DF, Jones PA. Degradation of connective tissue matrices by macrophages. III. Morphological and biochemical studies on extracellular, pericellular and intracellular events in matrix proteolysis by macrophages in culture. J Exp Med 1980;152:1537-1553. (Pubitemid 11210335)
    • (1980) Journal of Experimental Medicine , vol.152 , Issue.6 , pp. 1537-1553
    • Werb, Z.1    Bainton, D.F.2    Jones, P.A.3
  • 29
    • 47849105932 scopus 로고    scopus 로고
    • Roles for proteinases in the pathogenesis of chronic obstructive pulmonary disease
    • Owen CA. Roles for proteinases in the pathogenesis of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis 2008;3:253-268. (Pubitemid 352037885)
    • (2008) International Journal of COPD , vol.3 , Issue.2 , pp. 253-268
    • Owen, C.A.1
  • 31
    • 0002016013 scopus 로고
    • Elastases: Catalytic and biological properties
    • Mecham RP, editor. Orlando: Academic Press
    • Bieth JG. Elastases: catalytic and biological properties. In Mecham RP, editor. Regulation of matrix accumulation. Orlando: Academic Press; 1986. pp. 217-320.
    • (1986) Regulation of Matrix Accumulation , pp. 217-320
    • Bieth, J.G.1
  • 32
    • 0022852281 scopus 로고
    • 1-antitrypsin: Molecular pathology, leukocytes, and tissue damage
    • Carrell RW. Alpha1-antitrypsin: molecular pathology, leukocytes, and tissue damage. J Clin Invest 1986;78:1427-1431. (Pubitemid 17219502)
    • (1986) Journal of Clinical Investigation , vol.78 , Issue.6 , pp. 1427-1431
    • Carrell, R.W.1
  • 35
    • 77049113770 scopus 로고    scopus 로고
    • The tissue inhibitors of metalloproteinases (TIMPS): An ancient family with structural and functional diversity
    • Brew K, Nagase H. The tissue inhibitors of metalloproteinases (TIMPS): an ancient family with structural and functional diversity. Biochim Biophys Acta 2010;1803:55-71.
    • (2010) Biochim Biophys Acta , vol.1803 , pp. 55-71
    • Brew, K.1    Nagase, H.2
  • 36
    • 0021984232 scopus 로고
    • 1-protease inhibitor in bronchoalveolar lavage fluid
    • Abboud RT, Fera T, Richter A, Tabona MZ, Johal S. Acute effect of smoking on the functional activity of alpha1-protease inhibitor in bronchoalveolar lavage fluid. Am Rev Respir Dis 1985;131:79-85. (Pubitemid 15161969)
    • (1985) American Review of Respiratory Disease , vol.131 , Issue.1 , pp. 79-85
    • Abboud, R.T.1    Fera, T.2    Richter, A.3
  • 37
    • 0020322233 scopus 로고
    • Solid-phase radioimmunoassay for estimation of elastin peptides in human sera
    • Darnule TV, McKee M, Darnule AT, Turino GM, Mandl I. Solid-phase radioimmunoassay for estimation of elastin peptides in human sera. Anal Biochem 1982;122:302-307.
    • (1982) Anal Biochem , vol.122 , pp. 302-307
    • Darnule, T.V.1    McKee, M.2    Darnule, A.T.3    Turino, G.M.4    Mandl, I.5
  • 38
    • 0018183681 scopus 로고
    • Urinary excretion of elastin peptides containing desmosine after intratracheal injection of elastase in hamsters
    • Goldstein RA, Starcher BC. Urinary excretion of elastin peptides containing desmosine after intratracheal injection of elastin in hamsters. J Clin Invest 1978;61:1286-1290. (Pubitemid 8324153)
    • (1978) Journal of Clinical Investigation , vol.61 , Issue.5 , pp. 1286-1290
    • Goldstein, R.A.1    Starcher, B.C.2
  • 40
    • 0020016250 scopus 로고
    • Antibodies to elastin
    • Starcher BC. Antibodies to elastin. Methods Enzymol 1982;82:759-762.
    • (1982) Methods Enzymol , vol.82 , pp. 759-762
    • Starcher, B.C.1
  • 41
    • 0021827757 scopus 로고
    • Utilization of a peroxidase antiperoxidase complex in an enzyme-linked immunosorbent assay of elastin-derived peptides in human plasma
    • Kucich U, Christner P, Lippmann M, et al. Utilization of a peroxidase antiperoxidase complex in an enzyme-linker immunosorbent assay of elastin-derived peptides in human plasma. Am Rev Respir Dis 1985;131:709-713. (Pubitemid 15066854)
    • (1985) American Review of Respiratory Disease , vol.131 , Issue.5 , pp. 709-713
    • Kucich, U.1    Christner, P.2    Lippmann, M.3
  • 43
    • 0026396692 scopus 로고
    • Measurement of urinary desmosine by isotope dilution and high performance liquid chromatography. Correlation between elastase-induced air-sace enlargement in the hamster and elevation of urinary desmosine
    • Stone PJ, Bryan-Rhafdi J, Lucey EC, Ciccolella DE, Crombie G, Faris B, Snider GL, Franzblau C. Measurement of urinary desmosine by isotope dilution and high performance liquid chromatography. Correlation between elastase-induced air-sace enlargement in the hamster and elevation of urinary desmosine. Am Rev Respir Dis 1991;144:284-290.
    • (1991) Am Rev Respir Dis , vol.144 , pp. 284-290
    • Stone, P.J.1    Bryan-Rhafdi, J.2    Lucey, E.C.3    Ciccolella, D.E.4    Crombie, G.5    Faris, B.6    Snider, G.L.7    Franzblau, C.8
  • 44
    • 0019186346 scopus 로고
    • Desmosine radioimmunoassay for measuring elastin degradation in vivo
    • Harel S, Janoff A, Yu SY, Hurewitz A, Bergofsky EH. Desmosine radioimmunoassay for measuring elastin degradation in vivo. Am Rev Respir Dis 1980;122:769-773. (Pubitemid 11194225)
    • (1980) American Review of Respiratory Disease , vol.122 , Issue.5 I , pp. 769-773
    • Harel, S.1    Janoff, A.2    Yu, S.Y.3
  • 48
    • 34248566919 scopus 로고    scopus 로고
    • Measurements of desmosine and isodesmosine by mass spectrometry in COPD
    • DOI 10.1378/chest.06-2251
    • Ma S, Lin YY, Turino GM. Measurement of desmosine and isodesmosine by mass spectrometry in COPD. Chest 2007;131:1363-1371. (Pubitemid 46762340)
    • (2007) Chest , vol.131 , Issue.5 , pp. 1363-1371
    • Ma, S.1    Lin, Y.Y.2    Turino, G.M.3
  • 49
    • 0018712731 scopus 로고
    • Neutrophil lysosomal elastase activity in normal subjects and in patients with chronic obstructive pulmonary disease
    • Rodriguez JR, Seals JE, Radin A, Lin JS, Mandl I, Turino GM. Neutrophil lysosomal elastase activity in normal subjects and in patients with chronic obstructive pulmonary disease. Am Rev Respir Dis 1979;119:409-417. (Pubitemid 10231998)
    • (1979) American Review of Respiratory Disease , vol.119 , Issue.3 , pp. 409-417
    • Rodriguez, J.R.1    Seals, J.E.2    Radin, A.3
  • 50
    • 80052958371 scopus 로고    scopus 로고
    • Quantitation of desmosine and isodesmosine in urine, plasma, and sputum by LC-MS/MS as biomarkers for elastin degradation
    • Ma S, Turino GM, Lin YY. Quantitation of desmosine and isodesmosine in urine, plasma, and sputum by LC-MS/MS as biomarkers for elastin degradation. J Chromatography B 2011;879:1893-1898.
    • (2011) J Chromatography B , vol.879 , pp. 1893-1898
    • Ma, S.1    Turino, G.M.2    Lin, Y.Y.3
  • 52
    • 70249128358 scopus 로고    scopus 로고
    • The effect of tiotropium (TIO) on levels of desmosine and isodesmosine (D/I) in urine, plasma and sputum in COPD
    • Ma S, Lin YY, Turino GM. The effect of tiotropium (TIO) on levels of desmosine and isodesmosine (D/I) in urine, plasma and sputum in COPD. Respir Res 2009;10:12.
    • (2009) Respir Res , vol.10 , pp. 12
    • Ma, S.1    Lin, Y.Y.2    Turino, G.M.3
  • 57
    • 0018893350 scopus 로고
    • Chemotactic activity of elastinderived peptides
    • Senior RM, Griffin GL, Mecham RP. Chemotactic activity of elastinderived peptides. J Clin Invest 1980;66:859-862.
    • (1980) J Clin Invest , vol.66 , pp. 859-862
    • Senior, R.M.1    Griffin, G.L.2    Mecham, R.P.3
  • 58
    • 0021170197 scopus 로고
    • Val-Gly-Val-Ala-Pro-Gly, a repeating peptide in elastin, is chemotactic for fibroblasts and monocytes
    • Senior RM, Griffin GL, Mecham RP, Wrenn DS, Prasad KU, Urry DW. Val-Gly-Val-Ala-Pro-Gly, a repeating peptide in elastin, is chemotactic for fibroblasts and monocytes. J Cell Biol 1985;99:870-874.
    • (1985) J Cell Biol , vol.99 , pp. 870-874
    • Senior, R.M.1    Griffin, G.L.2    Mecham, R.P.3    Wrenn, D.S.4    Prasad, K.U.5    Urry, D.W.6
  • 59
    • 0019519757 scopus 로고
    • Elastin fragments attract macrophage precursors to diseased sites in pulmonary emphysema
    • Hunninghake GW, Davidson JM, Rennard S, Szapiel S, Gadek JE, Crystal RG. Elastin fragments attract macrophage precursors to diseased sites in pulmonary emphysema. Science 1981;212:925-927. (Pubitemid 11120475)
    • (1981) Science , vol.212 , Issue.4497 , pp. 925-927
    • Hunninghake, G.W.1    Davidson, J.M.2    Rennard, S.3
  • 61
    • 0027717916 scopus 로고
    • Peptide sequences selected by BA4, a tropoelastin-specific monoclonal antibody, are ligands for the 67-kilodalton bovine elastin receptor
    • DOI 10.1021/bi00211a052
    • Grosso LE, Scott M. Peptide sequences selected by BA4, a tropoelastinspecific monoclonal antibody, are ligands for the 67-kilodalton bovine elastin receptor. Biochemistry 1993;32:13369-13374. (Pubitemid 24005949)
    • (1993) Biochemistry , vol.32 , Issue.48 , pp. 13369-13374
    • Grosso, L.E.1    Scott, M.2
  • 62
    • 0032513204 scopus 로고    scopus 로고
    • The 67-kDa enzymatically inactive alternatively spliced variant of beta-galactosidase is identical to the elastin/laminin-binding protein
    • Privitera S, Prody CA, Callahan JW, Hinek A. The 67-kDa enzymatically inactive alternatively spliced variant of beta-galactosidase is identical to the elastin/laminin-binding protein. J Biol Chem 1998;273:6319-6327.
    • (1998) J Biol Chem , vol.273 , pp. 6319-6327
    • Privitera, S.1    Prody, C.A.2    Callahan, J.W.3    Hinek, A.4
  • 63
    • 77957995597 scopus 로고    scopus 로고
    • Characterization of peptide fragments from lung elastin degradation in chronic obstructive pulmonary disease
    • He J, Turino GM, Lin YY. Characterization of peptide fragments from lung elastin degradation in chronic obstructive pulmonary disease. Exp Lung Res 2010;36:548-557.
    • (2010) Exp Lung Res , vol.36 , pp. 548-557
    • He, J.1    Turino, G.M.2    Lin, Y.Y.3
  • 64
    • 79251585548 scopus 로고    scopus 로고
    • Smoke exposure as a determinant of autoantibody titre in {alpha}1-antitrypsin deficiency and COPD
    • Wood AM, dePablo P, Buckley CD, Ahmad A, Stockley RA. Smoke exposure as a determinant of autoantibody titre in {alpha}1-antitrypsin deficiency and COPD. Eur Respir J 2010;37:32-38.
    • (2010) Eur Respir J , vol.37 , pp. 32-38
    • Wood, A.M.1    DePablo, P.2    Buckley, C.D.3    Ahmad, A.4    Stockley, R.A.5


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