Oxidative phosphorylation flexibility in the liver of mice resistant to high-fat diet-induced hepatic steatosis

Diabetes

Volumn 60, Issue 9, 2011, Pages 2216-2224

  Poussin, Carinne ^a   Ibberson, Mark ^a,b   Hall, Diana ^a   Ding, Jun ^a   Soto, Jamie ^c   Abel, E Dale ^c   Thorens, Bernard ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; TRANSCRIPTOME;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FATTY LIVER; GENE EXPRESSION PROFILING; LIPID DIET; LIVER MITOCHONDRION; MALE; MOUSE; NONHUMAN; OBESITY; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; RESPIRATORY CHAIN; TRANSCRIPTOMICS; UPREGULATION;

ANIMALS; DIETARY FATS; FATTY LIVER; INSULIN; INSULIN RESISTANCE; LIVER; MICE; MITOCHONDRIA, LIVER; OXIDATIVE PHOSPHORYLATION; RNA, MESSENGER;

EID: 80052908820     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db11-0338     Document Type: Article

References (37)

1. Postic C, Girard J. Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice. J Clin Invest 2008;118:829-838 (Pubitemid 351364588)
2. Cai D, Yuan M, Frantz DF, et al. Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB. Nat Med 2005;11:183-190 (Pubitemid 40321354)
3. de Luca C, Olefsky JM. Inflammation and insulin resistance. FEBS Lett 2008;582:97-105 (Pubitemid 50010731)
4. Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006;444: 860-867 (Pubitemid 46024993)
5. Sethi JK, Vidal-Puig AJ. Thematic review series: adipocyte biology. Adipose tissue function and plasticity orchestrate nutritional adaptation. J Lipid Res 2007;48:1253-1262 (Pubitemid 47312027)
6. Biddinger SB, Hernandez-Ono A, Rask-Madsen C, et al. Hepatic insulin resistance is sufficient to produce dyslipidemia and susceptibility to atherosclerosis. Cell Metab 2008;7:125-134 (Pubitemid 351168555)
7. Surwit RS, Feinglos MN, Rodin J, et al. Differential effects of fat and sucrose on the development of obesity and diabetes in C57BL/6J and A/J mice. Metabolism 1995;44:645-651
8. Hall D, Poussin C, Velagapudi VR, et al. Peroxisomal and microsomal lipid pathways associated with resistance to hepatic steatosis and reduced proinflammatory state. J Biol Chem 2010;285:31011-31023
9. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159 (Pubitemid 17064313)
10. De Fourmestraux V, Neubauer H, Poussin C, et al. Transcript profiling suggests that differential metabolic adaptation of mice to high fat diet is associated with changes in liver to muscle lipid fluxes. J Biol Chem 2004; 279:50743-50753 (Pubitemid 40017812)
11. Gentleman RC, Carey VJ, Bates DM, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 2004;5:R80
12. Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA 2005;102:15545-15550 (Pubitemid 41528093)
13. Mootha VK, Lindgren CM, Eriksson KF, et al. PGC-1alpha-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes. Nat Genet 2003;34:267-273 (Pubitemid 36792858)
14. O'Neill BT, Kim J, Wende AR, et al. A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy. Cell Metab 2007;6:294-306 (Pubitemid 47450187)
15. Zhang Y, Soto J, Park K, et al. Nuclear receptor SHP, a death receptor that targets mitochondria, induces apoptosis and inhibits tumor growth. Mol Cell Biol 2010;30:1341-1356
16. Cantó C, Auwerx J. PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure. Curr Opin Lipidol 2009;20:98-105
17. Larrouy D, Laharrague P, Carrera G, et al. Kupffer cells are a dominant site of uncoupling protein 2 expression in rat liver. Biochem Biophys Res Commun 1997;235:760-764 (Pubitemid 27326558)
18. Lowell BB, Shulman GI. Mitochondrial dysfunction and type 2 diabetes. Science 2005;307:384-387 (Pubitemid 40139974)
19. Wisløff U, Najjar SM, Ellingsen O, et al. Cardiovascular risk factors emerge after artificial selection for low aerobic capacity. Science 2005;307:418-420 (Pubitemid 40139985)
20. Rabøl R, Boushel R, Dela F. Mitochondrial oxidative function and type 2 diabetes. Appl Physiol Nutr Metab 2006;31:675-683
21. Dahlman I, Forsgren M, Sjögren A, et al. Downregulation of electron transport chain genes in visceral adipose tissue in type 2 diabetes independent of obesity and possibly involving tumor necrosis factor-alpha. Diabetes 2006;55:1792-1799 (Pubitemid 44324134)
22. Misu H, Takamura T, Matsuzawa N, et al. Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes. Diabetologia 2007;50:268-277
23. Pospisilik JA, Knauf C, Joza N, et al. Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes. Cell 2007;131:476-491 (Pubitemid 350017761)
24. Takamura T, Misu H, Matsuzawa-Nagata N, et al. Obesity upregulates genes involved in oxidative phosphorylation in livers of diabetic patients. Obesity (Silver Spring) 2008;16:2601-2609
25. Boss O, Hagen T, Lowell BB. Uncoupling proteins 2 and 3: potential regulators of mitochondrial energy metabolism. Diabetes 2000;49:143-156 (Pubitemid 30070991)
26. Horimoto M, Fülöp P, Derdák Z, Wands JR, Baffy G. Uncoupling protein-2 deficiency promotes oxidant stress and delays liver regeneration in mice. Hepatology 2004;39:386-392 (Pubitemid 38222179)
27. Nègre-Salvayre A, Hirtz C, Carrera G, et al. A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation. FASEB J 1997;11:809-815 (Pubitemid 27349566)
28. Chance B, Sies H, Boveris A. Hydroperoxide metabolism in mammalian organs. Physiol Rev 1979;59:527-605 (Pubitemid 9236599)
29. Chavin KD, Yang S, Lin HZ, et al. Obesity induces expression of uncoupling protein-2 in hepatocytes and promotes liver ATP depletion. J Biol Chem 1999;274:5692-5700 (Pubitemid 29109222)
30. Tsuboyama-Kasaoka N, Sano K, Shozawa C, Osaka T, Ezaki O. Studies of UCP2 transgenic and knockout mice reveal that liver UCP2 is not essential for the antiobesity effects of fish oil. Am J Physiol Endocrinol Metab 2008; 294:E600-E606 (Pubitemid 351355231)
31. Burcelin R, Crivelli V, Dacosta A, Roy-Tirelli A, Thorens B. Heterogeneous metabolic adaptation of C57BL/6J mice to high-fat diet. Am J Physiol Endocrinol Metab 2002;282:E834-E842 (Pubitemid 34654745)
32. Poussin C, Hall D, Minehira K, Galzin AM, Tarussio D, Thorens B. Different transcriptional control of metabolism and extracellular matrix in visceral and subcutaneous fat of obese and rimonabant treated mice. PLoS ONE 2008;3:e3385
33. Koza RA, Nikonova L, Hogan J, et al. Changes in gene expression fore-shadow diet-induced obesity in genetically identical mice. PLoS Genet 2006;2:e81
34. Singer JB, Hill AE, Burrage LC, et al. Genetic dissection of complex traits with chromosome substitution strains of mice. Science 2004;304:445-448 (Pubitemid 38495941)
35. Gaulton KJ, Nammo T, Pasquali L, et al. A map of open chromatin in human pancreatic islets. Nat Genet 2010;42:255-259
36. Kelley DE, Mandarino LJ. Fuel selection in human skeletal muscle in insulin resistance: a reexamination. Diabetes 2000;49:677-683 (Pubitemid 30339979)
37. Mandarino LJ, Consoli A, Jain A, Kelley DE. Interaction of carbohydrate and fat fuels in human skeletal muscle: impact of obesity and NIDDM. Am J Physiol 1996;270:E463-E470