Centella asiatica in food and beverage applications and its potential antioxidant and neuroprotective effect

International Food Research Journal

Volumn 18, Issue 4, 2011, Pages 1215-1222

  Hashim, P ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

Antioxidant; Beverage; Centella asiatica; Food; Neuroprotection

Indexed keywords

CENTELLA; CENTELLA ASIATICA;

EID: 80052874099     PISSN: 19854668     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (67)

1. Anonymous, 2011a. Pengaga. Downloaded from http://www.bio-asli.com/herb/daun.asp#pengaga on 21/03/11.
2. Anonymous, 2011b. Panduan Menanam Pegaga. Downloaded from http://www.organikpro.com/files/Pegaga-Panduan_Menanam.pdf on 21/03/11.
3. Anonymous, 2011c. Gotu Kola. Downloaded from http://www.indianmirror.com/ayurveda/gotu-kola.html on 22/03/11.
4. Apichartsrangkoon, A., Wongfhun, P., Michael, H. and Gordon, M. H. 2009. Flavor characterization of sugaradded pennywort (Centella asiatica L.) juices treated with ultra-high pressure and thermal processes. Journal of Food Science 9: C643-C646.
5. Aruoma, O. I. 1994. Nutrition and health aspects of free radicals and antioxidants. Food Chemical Toxicology 62: 671-683.
6. Bjelakovic, G., Nikolova, D., Gluud, L.L., Simonetti, R.G. and Gluud, C. 2007. Mortality in Randomized Trials of Antioxidant Supplements for Primary and Secondary Prevention. Systematic Review and Meta-analysis. American Medical Association 297: 842- 857.
7. Boely, C. 1975. Indication of titrated extract of Centellaasiatica in phlebology. Gaz Medical France 82: 741-744.
8. Bradwejn, J., Zhou, Y., Koszycki, D. and Shlik J., 2000.A double-blind, placebo-controlled study on theeffects of Gotu Kola (Centella asiatica) on acousticstartle response in healthy subjects. Journal of ClinicalPsychopharmacology 20: 680-684.
9. Brinkhaus, B., Lindner, M., Schuppan, D. and Hahn, E. G. 2000. Chemical, pharmacological and clinical profile of the East Asian medical plant Centella asiatica. Phytomedicine 7: 427-428.
10. Chew, K.K., Ng, S.Y., Thoo, M.Z., Wan Aida, W.M. and Ho. C.W. 2011. Effect of ethanol concentration, extraction time and extraction temperature on the recovery of phenolic compounds and antioxidant capacity of Centella asiatica. International Food Research Journal 18: 566- 573.
11. Dev, R. D. O., Mohamed, S., Hambali, Z. l. and Abu Samah, B. 2009. Comparison on cognitive effects of Centella asiatica in healthy middle age female and male volunteers. European Journal of Scientific Research. European Journal of Scientific Research 1: 553-565.
12. st edn. New York: CRC Press.
13. Flora, S. J. and Gupta, R. 2007. Beneficial effects of Centella asiatica aqueous extract against arsenicinduced oxidative stress and essential metal status in rats. Phytotheraphy Research 21: 980-988.
14. Gulcin, I., Oktay, M., Kirecci, E. and Kufrevioglu, O.I. 2003. Screening of antioxidant and antimicrobial activities of anise (Pimpinella anisum L.) seed extracts. Food Chemistry 83: 371-382.
15. Haleagrahara, N. and Ponnusanny, K. 2010. Neuroprotective effect of Centella asiatica extract (CAE) on experimentally induced parkinsonism in aged Sprague-Dawley rats. Journal of Toxicology Science 35: 41-47.
16. Hamid, A. A, Md Shah, Z., Muse, R. and Mohamed, S. 2002 Characterisation of antioxidative of Centella asiatica (L) Urban. Food Chemistry 77: 465-469.
17. Hashim, P., Sidek, H., Helan, M.H.M., Sabery, A., Palanisamy, U.D. and Ilham, M. 2011. Triterpene composition and bioactivities of Centella asiatica. Molecules 16: 1310-1322.
18. Huda-Faujan, N., Noriham A., Norrakiah, A. S. and Babji, A. S. 2007. Antioxidant activities of water extracts of some Malaysian herbs. ASEAN Food Journal 14: 61-68.
19. Hussin, M., Hamid, A. A., Mohamad, S., Saari, N., Bakar, F. and Dek, S. P. 2009. Modulation of lipid metabolism by Centella asiatica in oxidative stress rats. Journal of Food Science 74: H72-H78.
20. Inamdar, P. K., Teola, R. D., Ghogare, A. B. and de Souza, N. J. 1996. Determination of biologically active constituents in Centella asiatica. Journal of Chromatography A 742: 127-130.
21. James, J. T. and Dubery, I. A. 2009. Pentacyclic triterpenoids from the medicinal herb, Centella asiatica (L.) Urban. Molecules 14: 3922-3941.
22. James, J. T., Meyer, R. and Dubery, I. A. 2008. Characterisation of two phenotypes of Centella asiatica in Southern Africa through the consumption of four triterpenoids in callus, cell suspension and leaves. Plant Cell Tissue Organ Culture 94: 91-99.
23. Jamil, S. S., Qudsia, N. and Salam, M. 2007. Centella asiatica (Linn.) Urban - A review. Indian Journal of Natural Products and Resources 6: 158-170.
24. Jaswir, I., Hassan, T. and Said, M. Z. 2004. Efficacy of Malaysian plant extracts in preventing peroxidataion in model and food oil systems 53: 525-529.
25. Jayashree, G., Muraleedhara, G. K., Sudarslal, S. and Jacob, V. B. 2003. Antioxidant activity of Centella asiatica on lymphoma-bearing mice. Fitoterapia 74:431-434.
26. Kim, O. T., Bang, K. H., Shin, Y. S., Lee, M. J., Jung, S. J., Hyun, D. Y., Kim, Y. C., Seong, N. S., Cha, S.W. and Hwang, B. 2007. Enhanced production of asiaticoside from hairy root cultures of Centella asiatica (L.) Urban elicited by methyl jasmonate. Plant Cell Reports 26: 1941-1949
27. Kim, O. T., Kim, S. H., Ohyama, K., Muranaka, T., Choi, Y. E., Lee, H. Y., Kim, M. Y. and Hwang, B. 2010 Upregulation of phytosterol and triterpene biosynthesis in Centella asiatica hairy roots over expressed ginseng farnesyl diphospahte synthase. Plant Cell Reports 29: 403-411.
28. Kimura, Y., Sumiyoshi, M., Samukawa, K., Satake N. and Sakanaka M., 2008. Facilitating action of asiaticoside at low doses on burn wound repair and its mechanism. European Journal of Pharmacology 584: 415-421.
29. Kormin, S. 2005. The effect of heat processing on triterpene glycosides and antioxidant activity of herbal pegaga (Centella asiatica L. urban) drink. Skudai, Malaysia: University Technology Malaysia, MSc Thesis.
30. Kumar, V. H. V. and Gupta, Y. K. 2002. Effect of different extracts of Centella asiatica on cognition and markers of oxidative stress in rats. Journal of Ethnopharmacology 79: 253-260.
31. Ling, A. P.K. 2004. Triterpene production in Centella asiatica (l.) urban (pegaga) callus and cell suspension cultures. Serdang, Malaysia: Universiti Putra Malaysia, PhD Thesis.
32. Loiseau, A. and Mercier, M. 2000. Centella asiatica and skin care. Cosmetics and Toiletries Magazine 115: 63-67.
33. Mohd Ilham, A. 1998. Opportunities on the planting of medicinal and herbal plants in Malaysia. Planter 74: 339-342
34. Nath, S. and Buragohain, A. K. 2005. Establishment of callus and cell suspension cultures of Centella asiatica, Biological Plantarum 49: 411-413.
35. Naithani, V., Nair, S. and Kakkar, P. 2006. Decline in antioxidant capacity of Indian herbal teas during storage and its relation to phenolic content. Food Research International 39: 176-181.
36. Ong, M. K. 2008. Optimization of in vitro cultures and effects of elicitation on the flavonoid contents of pegaga (Centella asiatica L. Urban). Serdang, Malaysia: Universiti Putra Malaysia, MSc Thesis.
37. Oyedeji, O. A. and Adayan, A. J. 2005. Chemical composition and antibacterial activity of the essential oil of Centella asiatica growing in South Africa. Journal of Pharmaceutical Biology 43: 249-252.
38. Paocharoen, V. 2010. The efficiency and side effects of oral Centella asiatica extract for wound healing promotion in diabetic wound patients. Journal of Medical Association Thailand 93: S166- S169.
39. Pittella, F., Dutra, R. C., Junior, D. D., Lopes, M. T. and Barbosa, N. 2009. Antioxidant and cytotoxic activites of Centella asiatica (L) Urb. International Journal of Molecular Science 10: 3713-3721.
40. Ponnusamy, K., Mohan, M. and Nagaraja, H.S. 2008. Protective antioxidant effect of Centella asiatica bioflavonoids on lead acetate induced neurotoxicity. Medical Journal of Malaysia 63: 102.
41. Punturee, K., Wild, C. P. and Vinitketkumneun, U. 2004. Thai medicinal plants modulate nitric oxide and tumor necrosis factor-alpha in J774.2 mouse macrophages Journal of Ethnopharmacology. 95: 183-189.
42. Qin, L. P., Ling, R. X., Zhang, W. D. et al. 1998. Essential oil from Centella asiatica and its antidepressant activity. Di Er Jun Yi Da Xue Xue Bao (Second Military Medical University) 19: 186-187.
43. Rajadurai, M. and Prince, P. S. M. 2006. Preventive effect of naringin on lipid peroxide and antioxidants in isoproterenol-induced cardiotoxicity in Wistar rats: biochemical and histopathological evidence. Toxicology 228: 259-268.
44. Ramanathan, M., Sivakumar, S., Anandvijayakumar, P. R., Saravanababu, C. and Pandian, P. R. 2007. Neuroprotective evaluation of standardized extract of Centella asiatica in mono sodium glutamate treated rats. Indian Journal Experimental Biology 45: 425-431.
45. Raza, S.A., Rashid, A., Qureshi, F.A., Asim, M.F. and William, J. 2009. Analytical Investigation of oxidative deterioration of sunflower oil stored under different conditions. Biharean Biologist 3: 93- 97.
46. Sahelian, R. 2011d. Galantamine supplement benefit, side effects, dosage information, risks, danger, no prescription required, use for Alzheimer's disease. Downloaded from http://www.raysahelian.com/galantamine.html on 22/03/11.
47. Shinomol, K. G. and Muralidhara. 2008. Prophylactic neuroprotective property of Centella asiatica against 3-nitropropionic acid induced oxidative stress and mitochondrial dysfunctions in brain regions of prepubertal mice. Neurotoxicology 29: 948-57.
48. Shinomol, K. G., Ravikumar, H. and Muralidhara. 2010. Prophylaxis with Centella asiatica confers protection to prepubertal mice against 3-nitropropionic-acidinduced oxidative stress in brain. Phytotheraphy Research 24: 885-892.
49. Shukla, A., Rasik, A. M. and Dhawan, B. N. 1999. Asiaticoside-induced elevation of antioxidant levels in healing wounds. Phytotheraphy Research 13: 50-54.
50. Singh, R. H., Narsimhamurthy, K. and Singh G. 2008. Neuronutrient impact of Ayurvedic Rasayana therapy in brain aging. Biogerontology 9: 369-374.
51. Subathra, M., Shila, S., Devi, M. A. and Panneerselvam, C. 2005. Emerging role of Centella asiatica in improving age-related neurological antioxidant status. Experimental Gerontology 40: 707-715.
52. Suntornsuk, L. and Anurukvorakun, O. 2005. Precision improvement for the analysis of flavonoids in selected Thai plants by capillary zone electrophoresis. Electrophoresis 26: 648-660.
53. Tan, P.W., Tan, C.P. and Ho, C.W. 2011. Antioxidant properties: Effects of solid-to-solvent ratio on antioxidant compounds and capacities of Pegaga (Centella asiatica). International Food Research Journal 18: 553-558.
54. th ed. Malaysian Food Composition Database Programme, p.16. Kuala Lumpur: Institute of Medical Research.
55. Thomas, M. T., Kurup, R., Johnson, A. J., Chandrika, S. P., Mathew, P. J., Dan, M. and Baby, S. 2010. Elite genotypes.chemotypes, with high contents of madecassoside and asiaticoside from sixty accessions of Centella asiatica of South India and the Andaman islands: for cultivation and utility in cosmetic and herbal drug applications. Industrial Crop and Products 32: 545- 550.
56. Tiwari, S., Singha, S., Patwardhan, K., Gehlot, S. and Gambhira, I. S. 2008. Effect of Centella asiatica on mild cognitive impairment (mci) and other common age-related clinical problems. Digest Journal of Nanomaterials and Biostructures 3: 215 - 220.
57. Tolkah, N. M. 1999. Genetic variation of Centella asiatica based on randomly amplified polymorphic DNA. Ethnobotanical Journal 22: 7-13.
58. Ullah, M. O., Sultana, S., Haque, A. and Tasmin, S. 2009. Antimicrobial, cytotoxic and antioxidant of Centella asiatica. European Journal of Scientific Research 30: 260-264.
59. Vimala, S., Adenan, M. I., Ahmad, A. R. and Shahdan, R. 2003. Nature's choice to wellness: antioxidant vegetables/ulam. Siri Alam dan Rimba No. 7. Kuala Lumpur: FRIM. p. 90-92.
60. Wangrangsimakul, K. 1999. Treatment of recurrent oral ophthous ulcerations. Annal Dentistry University Malaya 6: 58-59.
61. Wattanathorn, J., Mator, L., Muchimapura, S., Tongun. T., Pasuriwong, O., Piyawatkul, N., Yimtae, K., Sripanidkulchai, B. and Singkhoraard, J. 2008. Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica. Journal of Ethnopharmacology 116: 325-332.
62. Wijeweera, P., Arnason, J.T., Koszycki, D. and Merali, Z. 2006. Evaluation of anxiolytic properties of Gotukola (Centella asiatica) extracts and asiaticoside in rat behavioral models. Phytomedicine 13: 668-676.
63. Wongfhun, P., Gordon, M. H. and Apichartsrangkoon, A. 2010. Flavour characterization of fresh and processed pennywort (Centella asiatica L.) juices. Food Chemistry 119: 69-74.
64. Young, I. S. and Woodside, J. V. 2001. Antioxidants in health and disease. Journal of Clinical Pathology 54: 176-186.
65. Zainol, M. K. M. 2004. Determination of flavonoids in Centella asiatica (L.) Urban and their utilization in herbal noodles. Serdang, Malaysia: Universiti Putra Malaysia, MSc Thesis.
66. Zainol, N.A., Voo, S. C., Sarmidi, M. R. and Aziz, R. A. 2008. Profiling of Centella asiatica (L.) Urban extract. The Malaysian Journal of Analytical Sciences 12: 322-327.
67. Zheng, C. J. and Qin, L.P. 2007. Chemical components of Centella asiatica and their bioactives. Journal of Chinese Integrative Medicine 5: 348-351.