Overexpression of NUDT7, a candidate quantitative trait locus for pork color, downregulates heme biosynthesis in L6 myoblasts

Meat Science

Volumn 86, Issue 3, 2010, Pages 728-732

  Taniguchi, Masaaki ^a   Hayashi, Takeshi ^a   Nii, Masahiro ^b   Yamaguchi, Tomomi ^b   Fujishima Kanaya, Naoe ^c   Awata, Takashi ^a   Mikawa, Satoshi ^a  

^a NATIONAL INSTITUTE OF AGROBIOLOGICAL SCIENCES   (Japan)

^b Livestock Research Institute   (Japan)

^c Institute of the Society for Techno innovation of Agriculture   (Japan)

Author keywords

Differentiation; Gene expression; Heme biosynthesis; Meat color; QTL; Swine

Indexed keywords

DIFFERENTIATION; HEME BIOSYNTHESIS; MEAT COLOR; QTL; SWINE;

AGRICULTURE; BIOCHEMISTRY; BIOSYNTHESIS; COLOR; MAMMALS; MEATS; MUSCLE; PORPHYRINS;

GENE EXPRESSION;

HEME; INORGANIC PYROPHOSPHATASE; MESSENGER RNA;

ANIMAL; ARTICLE; BIOSYNTHESIS; CELL DIFFERENTIATION; COLOR; DOWN REGULATION; FOOD HANDLING; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; MEAT; METABOLISM; MYOBLAST; QUANTITATIVE TRAIT LOCUS; RAT; SKELETAL MUSCLE; SWINE;

ANIMALS; CELL DIFFERENTIATION; COLOR; DOWN-REGULATION; FOOD TECHNOLOGY; GENE EXPRESSION; HEME; MEAT; MUSCLE, SKELETAL; MYOBLASTS; PYROPHOSPHATASES; QUANTITATIVE TRAIT LOCI; RATS; RNA, MESSENGER; SUS SCROFA; TRANSFECTION;

MAMMALIA; PIERIS BRASSICAE; RATTUS; SUIDAE; SUS; SUS SCROFA;

EID: 80052866029     PISSN: 03091740     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.meatsci.2010.05.045     Document Type: Article

References (22)

1. Charnay P., Maniatis T. Transcriptional regulation of globin gene expression in the human erythroid cell line K562. Science 1983, 220(4603):1281-1283.
2. Cui Z., Chen X., Lu B., Park S.K., Xu T., Xie Z., Xue P., Hou J., Hang H., Yates J.R., Yang F. Preliminary quantitative profile of differential protein expression between rat L6 myoblasts and myotubes by stable isotope labeling with amino acids in cell culture. Proteomics 2009, 9(5):1274-1292.
3. Gasmi L., McLennan A.G. The mouse Nudt7 gene encodes a peroxisomal nudix hydrolase specific for coenzyme A and its derivatives. The Biochemical Journal 2001, 357(1):33-38.
4. Graber S.G., Woodworth R.C. Myoglobin expression in L6 muscle cells. Role of differentiation and heme. The Journal of Biological Chemistry 1986, 261(20):9150-9154.
5. Hornsey H.C. The colour of cooked cured pork. 1. Estimation of the nitric oxide-haem pigments. Journal of the Science of Food and Agriculture 1956, 7(8):534-541.
6. Huppertz C., Fischer B.M., Kim Y.B., Kotani K., Vidal-Puig A., Sliekeri L.J., Sloopi K.W., Lowell B.B., Kahn B.B. Uncoupling protein 3 (UCP3) stimulates glucose uptake in muscle cells through a phosphoinositide 3-kinase-dependent mechanism. The Journal of Biological Chemistry 2001, 276(16):12520-12529.
7. Jones P., Prudhoe K., Robson T. Oxidation of deuteroferrihaem by hydrogen peroxide. The Biochemical Journal 1973, 135(2):361-365.
8. Kim D., Jitrapakdee S., Thompson M. Differential regulation of the promoter activity of the mouse UCP2 and UCP3 genes by myoD and myogenin. Biochemistry and Molecular Biology 2007, 40(6):921-927.
9. Masuda T., Takahashi S. Chemiluminescent-based method for heme determination by reconstitution with horseradish peroxidase apo-enzyme. Analytical Biochemistry 2006, 355(2):307-309.
10. Medlock A.E., Dailey H.A. Regulation of mammalian heme biosynthesis. Tetrapyrroles: Birth, life and death 2007, 116-127. Landes Bioscience and Springer Science+Business Media, Austin, TX, USA. M. Warren, A.G. Smith (Eds.).
11. Newcom D.W., Stalder K.J., Baas T.J., Goodwin R.N., Parrish F.C., Wiegand B.R. Breed differences and genetic parameters of myoglobin concentration in porcine longissimus muscle. Journal of Animal Science 2004, 82(8):2264-2268.
12. Nii M., Hayashi T., Mikawa S., Tani F., Niki A., Mori N., Uchida Y., Fujishima-Kanaya N., Komatsu M., Awata T. Quantitative trait loci mapping for meat quality and muscle fiber traits in a Japanese wild boar×Large White intercross. Journal of Animal Science 2005, 83(2):308-315.
13. Ordway G.A., Garry D.J. Myoglobin: an essential hemoprotein in striated muscle. The Journal of Experimental Biology 2004, 207(20):3441-3446.
14. 2 pig population. Journal of Animal Science 2002, 80(11):2801-2808.
15. Pfaffl M.W., Georgieva T.M., Georgiev I.P., Ontsouka E., Hageleit M., Blum J.W. Real-time RT-PCR quantification of insulin-like growth factor (IGF)-1, IGF-1 receptor IGF-2, IGF-2 receptor, insulin receptor, growth hormone receptor, IGF-binding proteins 1, 2 and 3 in the bovine species. Domestic Animal Endocrinology 2002, 22(2):91-102.
16. Rajagopal A., Rao A.U., Amigo J., Tian M., Upadhyay S.K., Hall C., Uhm S., Mathew M.K., Fleming M.D., Paw B.H., Krause M., Hamza I. Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins. Nature 2008, 453(7198):1127-1131.
17. Ross J., Sautner D. Induction of globin mRNA accumulation by hemin in cultured erythroleukemic cells. Cell 1976, 8(4):513-520.
18. Sabourin L.A., Rudnicki M.A. The molecular regulation of myogenesis. Clinical Genetics 2000, 57(1):16-25.
19. Sono M., Roach M.P., Coulter E.D., Dawson J.H. Heme-containing oxygenases. Chemical Reviews 1996, 96(7):2841-2888.
20. Tanaka Y., Yamaguchi A., Fujikawa T., Sakuma K., Morita I., Ishii K. Expression of mRNA for specific fibroblast growth factors associates with that of the myogenic markers MyoD and proliferating cell nuclear antigen in regenerating and overloaded rat plantaris muscle. Acta Physiologica 2008, 194(2):149-159.
21. Taniguchi M., Hayashi T., Nii M., Yamaguchi T., Fujishima-Kanaya N., Awata T., Mikawa S. Fine mapping of quantitative trait loci for meat colour on SSC6: Analysis of the swine NUDT7 gene. Journal of Animal Science 2010, 88(1):23-31.
22. 2 crossbred pigs. Meat Science 2009, 81(1):108-115.