The mouse Nudt7 gene encodes a peroxisomal nudix hydrolase specific for coenzyme A and its derivatives

Biochemical Journal

Volumn 357, Issue 1, 2001, Pages 33-38

  Gasmi, L ^a   McLennan, A G ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Fatty acid oxidation; Peroxisomes; Pyrophosphatase

Indexed keywords

AMINO ACIDS; COENZYMES; ENZYME INHIBITION; ESCHERICHIA COLI; METABOLISM; TISSUE CULTURE;

KIDNEYS;

GENETIC ENGINEERING;

ACYL COENZYME A; COENZYME A; CYCLIC AMP; ENZYME VARIANT; FLUORIDE; GENE PRODUCT; HYBRID PROTEIN; HYDROLASE; MAGNESIUM ION; MANGANESE; NUDIX HYDROLASE; PANTETHEINE PHOSPHATE; PROTEIN NUDT7ALPHA; PROTEIN NUDT7BETA; PROTEIN PCD1P; RED FLUORESCENT PROTEIN; THIOREDOXIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ENZYME ANALYSIS; ENZYME SPECIFICITY; EXPRESSION VECTOR; GENE EXPRESSION REGULATION; GENE FUSION; HUMAN; HUMAN CELL; IC 50; KIDNEY; LIVER; LUNG; MOLECULAR CLONING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION; PEROXISOME; PRIORITY JOURNAL; PROTEIN MOTIF; SACCHAROMYCES CEREVISIAE; SEQUENCE HOMOLOGY; TISSUE DISTRIBUTION;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BRAIN; CLONING, MOLECULAR; COENZYME A; ESCHERICHIA COLI; FEMALE; HELA CELLS; HUMANS; ISOENZYMES; KIDNEY; KINETICS; LUNG; MICE; MOLECULAR SEQUENCE DATA; MYOCARDIUM; ORGAN SPECIFICITY; PEROXISOMES; PYROPHOSPHATASES; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; TRANSCRIPTION, GENETIC; VARIATION (GENETICS);

ANIMALIA; ESCHERICHIA COLI; SACCHAROMYCES CEREVISIAE;

EID: 0035397652     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/0264-6021:3570033     Document Type: Article

References (16)

1. The MutT proteins or 'nudix' hydrolases, a family of versatile, widely distributed, 'housecleaning' enzymes
2. The MutT motif family of nucleotide phosphohydrolases in man and human pathogens
3. Studies on the ADP-ribose pyrophosphatase subfamily of the Nudix hydrolases and tentative identification of trgB, a gene associated with tellurite resistance
4. The diadenosine hexaphosphate hydrolases from Schizosaccharomyces pombe and Saccharomyces cerevisiae are homologues of the human diphosphoinositol polyphosphate phosphohydrorase - Overlapping substrate specificities in a MutT-type protein
5. Discovery of molecular and catalytic diversity among human diphosphoinositol-polyphosphate phosphohydrolases - An expanding Nudt family
6. GDP-mannose mannosyl hydrolase catalyzes nucleophilic substitution at carbon, unlike all other nudix hydrolases
7. The Saccharomyces cerevisiae PCD1 gene encodes a peroxisomal nudix hydrolase active towards coenzyme A and its derivatives
8. 6-hexaphosphate hydrolase member of the MutT motif (nudix hydrolase) family
9. Cloning, expression and characterization of YSA1H, a human adenosine 5′-diphosphosugar pyrophosphatase possessing a MutT motif
10. The hydrolytic activity of bovine adrenal medullary plasma membranes towards diadenosine polyphosphates is due to alkaline phosphodiesterase-I
11. Determination of total protein
12. Interpreting DNA sequences: Some insights from studies on translation
13. The nudix hydrolases of Deinococcus radiodurans
14. Subcellular distribution of coenzyme A: Evidence for a separate coenzyme A pool in peroxisomes
15. Coenzyme A in purified peroxisomes is not freely soluble in the matrix but firmly bound to a matrix protein
16. Computational method to predict mitochondrially imported proteins and their targeting sequences