Ceruloplasmin deficiency reduces levels of iron and BDNF in the cortex and striatum of young mice and increases their vulnerability to stroke

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Texel, Sarah J ^a,b   Zhang, Jian ^a   Camandola, Simonetta ^b   Unger, Erica L ^c   Taub, Dennis D ^b   Koehler, Raymond C ^a   Harris, Z Leah ^d   Mattson, Mark P ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE ON AGING   (United States)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

^d VANDERBILT UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CERULOPLASMIN; IRON; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN ISCHEMIA; CELL METABOLISM; CELL VIABILITY; CERULOPLASMIN BLOOD LEVEL; CONTROLLED STUDY; CORPUS STRIATUM; HUMAN; HUMAN CELL; IRON CHELATION; LIPID PEROXIDATION; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DEFICIENCY; TRANSCRIPTION REGULATION; ANIMAL; BRAIN; CEREBRAL ARTERY DISEASE; CYTOLOGY; DISEASE MODEL; ENZYME IMMUNOASSAY; GENETICS; MALE; METABOLISM; MOUSE MUTANT; NEOSTRIATUM; NERVE CELL; NEUROBLASTOMA; PATHOLOGY; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; STROKE; TUMOR CELL CULTURE; WESTERN BLOTTING;

ANIMALIA; MUS;

ANIMALS; BLOTTING, WESTERN; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CERULOPLASMIN; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; HUMANS; IMMUNOENZYME TECHNIQUES; INFARCTION, MIDDLE CEREBRAL ARTERY; IRON; MALE; MICE; MICE, KNOCKOUT; NEOSTRIATUM; NEUROBLASTOMA; NEURONS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; STROKE; TUMOR CELLS, CULTURED;

EID: 80052863596     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025077     Document Type: Article

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