메뉴 건너뛰기




Volumn 39, Issue 10, 2011, Pages 969-976

Kinase suppressor of ras (ksr1) modulates multiple kit-ligand-dependent mast cell functions

Author keywords

[No Author keywords available]

Indexed keywords

F ACTIN; KINASE SUPPRESSOR OF RAS PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; P21 ACTIVATED KINASE; RAF PROTEIN; SCAFFOLD PROTEIN; STEM CELL FACTOR; UNCLASSIFIED DRUG;

EID: 80052861295     PISSN: 0301472X     EISSN: 18732399     Source Type: Journal    
DOI: 10.1016/j.exphem.2011.06.009     Document Type: Article
Times cited : (7)

References (30)
  • 1
    • 44349101991 scopus 로고    scopus 로고
    • Immunomodulatory mast cells: negative, as well as positive, regulators of immunity
    • Galli S.J., Grimbaldeston M., Tsai M. Immunomodulatory mast cells: negative, as well as positive, regulators of immunity. Nat Rev Immunol 2008, 8:478-486.
    • (2008) Nat Rev Immunol , vol.8 , pp. 478-486
    • Galli, S.J.1    Grimbaldeston, M.2    Tsai, M.3
  • 2
    • 41849095954 scopus 로고    scopus 로고
    • Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis
    • Piliponsky A.M., Chen C.C., Nishimura T., et al. Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis. Nat Med 2008, 14:392-398.
    • (2008) Nat Med , vol.14 , pp. 392-398
    • Piliponsky, A.M.1    Chen, C.C.2    Nishimura, T.3
  • 3
    • 33746642081 scopus 로고    scopus 로고
    • Mast cells can enhance resistance to snake and honeybee venoms
    • Metz M., Piliponsky A.M., Chen C.C., et al. Mast cells can enhance resistance to snake and honeybee venoms. Science 2006, 313:526-530.
    • (2006) Science , vol.313 , pp. 526-530
    • Metz, M.1    Piliponsky, A.M.2    Chen, C.C.3
  • 4
    • 9644269070 scopus 로고    scopus 로고
    • Mast cells promote homeostasis by limiting endothelin-1-induced toxicity
    • Maurer M., Wedemeyer J., Metz M., et al. Mast cells promote homeostasis by limiting endothelin-1-induced toxicity. Nature 2004, 432:512-516.
    • (2004) Nature , vol.432 , pp. 512-516
    • Maurer, M.1    Wedemeyer, J.2    Metz, M.3
  • 5
    • 33745225217 scopus 로고    scopus 로고
    • Mast cells can promote the development of multiple features of chronic asthma in mice
    • Yu M., Tsai M., Tam S.Y., Jones C., Zehnder J., Galli S.J. Mast cells can promote the development of multiple features of chronic asthma in mice. J Clin Invest 2006, 116:1633-1641.
    • (2006) J Clin Invest , vol.116 , pp. 1633-1641
    • Yu, M.1    Tsai, M.2    Tam, S.Y.3    Jones, C.4    Zehnder, J.5    Galli, S.J.6
  • 6
    • 0035911230 scopus 로고    scopus 로고
    • Inflammatory cells and cancer: think different!
    • Coussens L.M., Werb Z. Inflammatory cells and cancer: think different!. J Exp Med 2001, 193:F23-F26.
    • (2001) J Exp Med , vol.193
    • Coussens, L.M.1    Werb, Z.2
  • 7
    • 54549095884 scopus 로고    scopus 로고
    • Nf1-dependent tumors require a microenvironment containing Nf1+/- and c-kit-dependent bone marrow
    • Yang F.C., Ingram D.A., Chen S., et al. Nf1-dependent tumors require a microenvironment containing Nf1+/- and c-kit-dependent bone marrow. Cell 2008, 135:437-448.
    • (2008) Cell , vol.135 , pp. 437-448
    • Yang, F.C.1    Ingram, D.A.2    Chen, S.3
  • 8
    • 0025912874 scopus 로고
    • Induction of mast cell proliferation, maturation, and heparin synthesis by the rat c-kit ligand, stem cell factor
    • Tsai M., Takeishi T., Thompson H., et al. Induction of mast cell proliferation, maturation, and heparin synthesis by the rat c-kit ligand, stem cell factor. Proc Natl Acad Sci U S A 1991, 88:6382-6386.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 6382-6386
    • Tsai, M.1    Takeishi, T.2    Thompson, H.3
  • 9
    • 0028886995 scopus 로고
    • Stem-cell factor, the kit ligand, induces direct degranulation of rat peritoneal mast cells in vitro and in vivo: dependence of the in vitro effect on period of culture and comparisons of stem-cell factor with other mast cell-activating agents
    • Taylor A.M., Galli S.J., Coleman J.W. Stem-cell factor, the kit ligand, induces direct degranulation of rat peritoneal mast cells in vitro and in vivo: dependence of the in vitro effect on period of culture and comparisons of stem-cell factor with other mast cell-activating agents. Immunology 1995, 86:427-433.
    • (1995) Immunology , vol.86 , pp. 427-433
    • Taylor, A.M.1    Galli, S.J.2    Coleman, J.W.3
  • 10
    • 0027716146 scopus 로고
    • The c-kit receptor, stem cell factor, and mast cells. What each is teaching us about the others
    • Galli S.J., Tsai M., Wershil B.K. The c-kit receptor, stem cell factor, and mast cells. What each is teaching us about the others. Am J Pathol 1993, 142:965-974.
    • (1993) Am J Pathol , vol.142 , pp. 965-974
    • Galli, S.J.1    Tsai, M.2    Wershil, B.K.3
  • 11
    • 0035796397 scopus 로고    scopus 로고
    • Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro
    • Ingram D.A., Hiatt K., King A.J., et al. Hyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitro. J Exp Med 2001, 194:57-69.
    • (2001) J Exp Med , vol.194 , pp. 57-69
    • Ingram, D.A.1    Hiatt, K.2    King, A.J.3
  • 12
    • 9144260570 scopus 로고    scopus 로고
    • Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells
    • Yang F.C., Ingram D.A., Chen S., et al. Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/- mast cells. J Clin Invest 2003, 112:1851-1861.
    • (2003) J Clin Invest , vol.112 , pp. 1851-1861
    • Yang, F.C.1    Ingram, D.A.2    Chen, S.3
  • 13
    • 33644537348 scopus 로고    scopus 로고
    • RabGEF1 regulates stem cell factor/c-Kit-mediated signaling events and biological responses in mast cells
    • Kalesnikoff J., Rios E.J., Chen C.C., et al. RabGEF1 regulates stem cell factor/c-Kit-mediated signaling events and biological responses in mast cells. Proc Natl Acad Sci U S A 2006, 103:2659-2664.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 2659-2664
    • Kalesnikoff, J.1    Rios, E.J.2    Chen, C.C.3
  • 14
    • 0033678937 scopus 로고    scopus 로고
    • Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells
    • Yang F.C., Kapur R., King A.J., et al. Rac2 stimulates Akt activation affecting BAD/Bcl-XL expression while mediating survival and actin function in primary mast cells. Immunity 2000, 12:557-568.
    • (2000) Immunity , vol.12 , pp. 557-568
    • Yang, F.C.1    Kapur, R.2    King, A.J.3
  • 15
    • 58149401317 scopus 로고    scopus 로고
    • Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells
    • McDaniel A.S., Allen J.D., Park S.J., et al. Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/- mast cells. Blood 2008, 112:4646-4654.
    • (2008) Blood , vol.112 , pp. 4646-4654
    • McDaniel, A.S.1    Allen, J.D.2    Park, S.J.3
  • 16
    • 33846916195 scopus 로고    scopus 로고
    • K-ras is critical for modulating multiple c-kit-mediated cellular functions in wild-type and Nf1+/- mast cells
    • Khalaf W.F., Yang F.C., Chen S., et al. K-ras is critical for modulating multiple c-kit-mediated cellular functions in wild-type and Nf1+/- mast cells. J Immunol 2007, 178:2527-2534.
    • (2007) J Immunol , vol.178 , pp. 2527-2534
    • Khalaf, W.F.1    Yang, F.C.2    Chen, S.3
  • 17
    • 0029850713 scopus 로고    scopus 로고
    • KSR modulates signal propagation within the MAPK cascade
    • Therrien M., Michaud N.R., Rubin G.M., Morrison D.K. KSR modulates signal propagation within the MAPK cascade. Genes Dev 1996, 10:2684-2695.
    • (1996) Genes Dev , vol.10 , pp. 2684-2695
    • Therrien, M.1    Michaud, N.R.2    Rubin, G.M.3    Morrison, D.K.4
  • 19
    • 2942531229 scopus 로고    scopus 로고
    • The molecular scaffold KSR1 regulates the proliferative and oncogenic potential of cells
    • Kortum R.L., Lewis R.E. The molecular scaffold KSR1 regulates the proliferative and oncogenic potential of cells. Mol Cell Biol 2004, 24:4407-4416.
    • (2004) Mol Cell Biol , vol.24 , pp. 4407-4416
    • Kortum, R.L.1    Lewis, R.E.2
  • 20
    • 9144244353 scopus 로고    scopus 로고
    • Phosphorylation regulates KSR1 stability, ERK activation, and cell proliferation
    • Razidlo G.L., Kortum R.L., Haferbier J.L., Lewis R.E. Phosphorylation regulates KSR1 stability, ERK activation, and cell proliferation. J Biol Chem 2004, 279:47808-47814.
    • (2004) J Biol Chem , vol.279 , pp. 47808-47814
    • Razidlo, G.L.1    Kortum, R.L.2    Haferbier, J.L.3    Lewis, R.E.4
  • 21
    • 20144373564 scopus 로고    scopus 로고
    • Expression of kinase suppressor of Ras1 enhances cisplatin-induced extracellular signal-regulated kinase activation and cisplatin sensitivity
    • Kim M., Yan Y., Kortum R.L., et al. Expression of kinase suppressor of Ras1 enhances cisplatin-induced extracellular signal-regulated kinase activation and cisplatin sensitivity. Cancer Res 2005, 65:3986-3992.
    • (2005) Cancer Res , vol.65 , pp. 3986-3992
    • Kim, M.1    Yan, Y.2    Kortum, R.L.3
  • 22
    • 35448966080 scopus 로고    scopus 로고
    • Role of kinase suppressor of Ras-1 in neuronal survival signaling by extracellular signal-regulated kinase 1/2
    • Szatmari E., Kalita K.B., Kharebava G., Hetman M. Role of kinase suppressor of Ras-1 in neuronal survival signaling by extracellular signal-regulated kinase 1/2. J Neurosci 2007, 27:11389-11400.
    • (2007) J Neurosci , vol.27 , pp. 11389-11400
    • Szatmari, E.1    Kalita, K.B.2    Kharebava, G.3    Hetman, M.4
  • 23
    • 0037373098 scopus 로고    scopus 로고
    • Overexpression of kinase suppressor of Ras upregulates the high-molecular-weight tropomyosin isoforms in ras-transformed NIH 3T3 fibroblasts
    • Janssen R.A., Kim P.N., Mier J.W., Morrison D.K. Overexpression of kinase suppressor of Ras upregulates the high-molecular-weight tropomyosin isoforms in ras-transformed NIH 3T3 fibroblasts. Mol Cell Biol 2003, 23:1786-1797.
    • (2003) Mol Cell Biol , vol.23 , pp. 1786-1797
    • Janssen, R.A.1    Kim, P.N.2    Mier, J.W.3    Morrison, D.K.4
  • 24
    • 0036239642 scopus 로고    scopus 로고
    • Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo
    • Nguyen A., Burack W.R., Stock J.L., et al. Kinase suppressor of Ras (KSR) is a scaffold which facilitates mitogen-activated protein kinase activation in vivo. Mol Cell Biol 2002, 22:3035-3045.
    • (2002) Mol Cell Biol , vol.22 , pp. 3035-3045
    • Nguyen, A.1    Burack, W.R.2    Stock, J.L.3
  • 25
    • 0034598363 scopus 로고    scopus 로고
    • Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo
    • Ingram D.A., Yang F.C., Travers J.B., et al. Genetic and biochemical evidence that haploinsufficiency of the Nf1 tumor suppressor gene modulates melanocyte and mast cell fates in vivo. J Exp Med 2000, 191:181-188.
    • (2000) J Exp Med , vol.191 , pp. 181-188
    • Ingram, D.A.1    Yang, F.C.2    Travers, J.B.3
  • 26
    • 0037111634 scopus 로고    scopus 로고
    • Lymphoproliferative defects in mice lacking the expression of neurofibromin: functional and biochemical consequences of Nf1 deficiency in T-cell development and function
    • Ingram D.A., Zhang L., McCarthy J., et al. Lymphoproliferative defects in mice lacking the expression of neurofibromin: functional and biochemical consequences of Nf1 deficiency in T-cell development and function. Blood 2002, 100:3656-3662.
    • (2002) Blood , vol.100 , pp. 3656-3662
    • Ingram, D.A.1    Zhang, L.2    McCarthy, J.3
  • 27
    • 78650193984 scopus 로고    scopus 로고
    • Nf1-/- Schwann cell-conditioned medium modulates mast cell degranulation by c-Kit-mediated hyperactivation of phosphatidylinositol 3-kinase
    • Chen S., Burgin S., McDaniel A., et al. Nf1-/- Schwann cell-conditioned medium modulates mast cell degranulation by c-Kit-mediated hyperactivation of phosphatidylinositol 3-kinase. Am J Pathol 2010, 177:3125-3132.
    • (2010) Am J Pathol , vol.177 , pp. 3125-3132
    • Chen, S.1    Burgin, S.2    McDaniel, A.3
  • 28
    • 34248563290 scopus 로고    scopus 로고
    • The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
    • Meloche S., Pouyssegur J. The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition. Oncogene 2007, 26:3227-3239.
    • (2007) Oncogene , vol.26 , pp. 3227-3239
    • Meloche, S.1    Pouyssegur, J.2
  • 29
    • 0033151608 scopus 로고    scopus 로고
    • Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis
    • Coussens L.M., Raymond W., Bergers G., et al. Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis. Genes Dev 1999, 13:1382-1397.
    • (1999) Genes Dev , vol.13 , pp. 1382-1397
    • Coussens, L.M.1    Raymond, W.2    Bergers, G.3
  • 30
    • 0037180757 scopus 로고    scopus 로고
    • Inflammation and cancer
    • Coussens L.M., Werb Z. Inflammation and cancer. Nature 2002, 420:860-867.
    • (2002) Nature , vol.420 , pp. 860-867
    • Coussens, L.M.1    Werb, Z.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.