Endothelial nitric oxide synthase gene Glu298Asp polymorphism and risk of preeclampsia in South East of Iran

African Journal of Biotechnology

Volumn 10, Issue 52, 2011, Pages 10712-10717

  Yaghmaei, Minoo ^a   Salimi, Saeedeh ^a,b   Mokhtari, Mojgan ^a   Naghavi, Anoosh ^b,c   Saravani, Mohsen ^a   Farajian Mashhadi, Farzaneh ^a,b  

^a ZAHEDAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ZAHEDAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TARBIAT MODARES UNIVERSITY   (Iran)

Author keywords

Nitric oxide synthase; Polymorphism; Preeclampsia; Pregnancy

Indexed keywords

GENOMIC DNA;

ADULT; ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; ENDOTHELIAL NITRIC OXIDE SYNTHASE GENE; ETHNIC DIFFERENCE; ETHNICITY; FEMALE; GENE FREQUENCY; GENE IDENTIFICATION; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HUMAN; IRAN; MAJOR CLINICAL STUDY; MARKER GENE; MOLECULAR PATHOLOGY; POLYMERASE CHAIN REACTION; PREECLAMPSIA; PREGNANT WOMAN; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK ASSESSMENT; RISK FACTOR;

EID: 80052856327     PISSN: 16845315     EISSN: None     Source Type: Journal    
DOI: 10.5897/ajb11.895     Document Type: Article

References (32)

1. Aggrawal PK, Jain V, Jha V (2010). Endothelial nitric oxide synthase, angiotensin-converting enzyme and angiotensinogen gene polymorphisms in hypertensive disorders of pregnancy. Hypertens. Res., 33(5): 473-7
2. Arngrimsson R, Hayward C, Nadaud S, Baldursdottir A, Walker JJ, Liston WA, Bjarnadottir RI, Brock DJ, Geirsson RT, Connor JM, Soubrier F (1997). Evidence for a familial pregnancy-induced hypertension locus in the eNOS-gene region. Am. J. Hum. Genet., 61: 354-362.
3. Benjafield AV, Morris BJ (2000). Association analyses of endothelial nitric oxide synthase gene polymorphisms in essential hypertension. Am. J. Hypertens., 13: 994-998.
4. Broughton Pipkin F (2001). Risk factors for preeclampsia. N Engl J Med., 344: 925-926.
5. Buhimschi IA, Saade GR, Chwalisz K, Garfield RE (1998). The nitric oxide pathway in pre-eclampsia: pathophysiological implications. Hum. Reprod. Update. 4: 25-42.
6. Chen LK, Huang CH, Yeh HM, Lee CN, Shyu MK, Hsieh FJ, Lai LP, Sun WZ (2007). Polymorphisms in the endothelial nitric oxide synthase gene may be protective against preeclampsia in a Chinese population. Reprod. Sci., 14(2): 175-81.
7. Elbaz A, Poirier O, Moulin T, Chedru F, Cambien F, Amarenco P (2000). Association between the Glu298Asp polymorphism in the endothelial constitutive nitric oxide synthase gene and brain infarction. The GENIC Investigators. Stroke, 31: 1634-1639.
8. Hakli T, Romppanen EL, Hiltunen M, Helisalmi S, Punnonen K, Heinonen S (2003). Endothelial nitric oxide synthase polymorphism in preeclampsia. J. Soc. Gynecol. Invest., 10: 154-157.
9. Hibi K, Ishigami T, Tamura K, Mizushima S, Nyui N, Fujita T, Ochiai H, Kosuge M, Watanabe Y, Yoshii Y, Kihara M, Kimura K, Ishii M, Umemura S (1998). Endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction. Hypertension, 32: 521-526.
10. Hocher B, Chen YP, Hugle S, Repey J, Krause K, Slowinski T, Godes M, Schaeffeler E, Guthmann F, Wauer R, Halle H, Gossing G, Pfab T (2008). Impact of maternal endothelial nitric oxide synthase gene polymorphisms on blood pressure, protein excretion and fetal outcome in pregnancy. J. Hum. Hypertens, 22(9): 641-7.
11. Kim YJ, Park HS, Lee HY, Ha EH, Suh SH, Oh SK, Yoo HS (2006). Reduced L-arginine level and decreased placental eNOS activity in preeclampsia. Placenta, 27(4-5): 438-44
12. Kobashi G, Yamada H, Ohta K, Kato E, Ebina Y, Fujimoto S (2001). Endothelial nitric oxide synthase gene (NOS3) variant and hypertensionin pregnancy. Am. J. Med. Genet., 103: 241-244.
13. Lade JA, Moses EK, Guo G, Wilton AN, Grehan M, Cooper DW, Brennecke SP (1999). The eNOS gene: a candidate for the preeclampsia susceptibility locus? Hypertens Pregnancy, 18: 81-93.
14. Landau R, Xie HG, Dishy V, Wood AJ, Stein CM, Smiley RM (2004). No association of the Asp298 variant of the endothelial nitric oxide synthase gene with preeclampsia. Am. J. Hypertens. 17(5 Pt 1): 391-4.
15. Lewis I, Lachmeijer G, Downing S, Dekker G, Glazebrook C, Clayton D, Morris NH, O'Shaughnessy KM (1999). Failure to detect linkage of preeclampsia to the region of the NOS3 locus on chromosome7q. Am. J. Hum. Genet., 64: 310-313.
16. Marsden PA, Heng HH, Scherer SW, Stewart RJ, Hall AV, Shi XM (1993). Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. J. Biol. Chem., 268: 17478-88.
17. Medica I, Kastrin A, Peterlin B (2007). Genetic polymorphisms in vasoactive genes and preeclampsia: a meta-analysis. Eur. J. Obstet. Gynecol. Reprod. Biol., 131(2): 115-28.
18. Noiri E, Satoh H, Taguchi J, Brodsky S, Nakao A, Ogawa Y, Nishijima S, Yokomizo T, Tokunaga K, Fujita T (2002). Association of eNOS Glu298Asp polymorphism with end-stage renal disease. Hypertension, 40: 535-540.16.
19. Salimi S, Firoozrai M, Zand H, Nakhaee A, Shafiee SM, Tavilani H, Mohebbi A (2010). Endothelial nitric oxide synthase gene Glu298Asp polymorphism in patients with coronary artery disease. Ann. Saudi Med., 30(1): 33-7.
20. Salonen Ros H, Lichtenstein P, Lipworth L, Cnattingius S (2000). Genetic effects on the liability of developing pre-eclampsia and gestational hypertension. Am. J. Med. Genet., 91: 256-260.
21. Sandrim VC, Palei AC, Cavalli RC, Araujo FM, Ramos ES, Duarte G, Tanus-Santos JE (2008). eNOS haplotypes associated with gestational hypertension or preeclampsia. Pharmacogenomics, 9(10): 1467-73.
22. Serrano NC, Casas JP, Diaz LA, Paez C, Mesa CM, Cifuentes R, Monterrosa A, Bautista A, Hawe E, Hingorani AD, Vallance P, Lopez-Jaramillo P (2004). Endothelial NO synthase genotype and risk of preeclampsia: a multicenter case-control study. Hypertension, 44(5): 702-7.
23. Sharma D, Singh A, Trivedi SS, Bhattacharjee J (2011). Intergenotypic variation of nitric oxide and inflammatory markers in preeclampsia: a pilot study in a North Indian population. Hum. Immunol., 72(5): 436-9.
24. Singh A, Sharma D, Raghunandan C, Bhattacharjee J (2010). Role of inflammatory cytokines and eNOS gene polymorphism in pathophysiology of pre-eclampsia. Am. J. Reprod. Immunol. 63(3): 244-51.
25. Tempfer CB, Dorman K, Deter RL, O'Brien WE, Gregg AR (2001). An endothelial nitric oxide synthase gene polymorphism is associated with preeclampsia. Hypertens. Pregnancy, 20: 107-118.
26. Tesauro M, Thompson WC, Rogliani P, Qi L, Chaudhary PP, Moss J (2004). Intracellular processing of endothelial nitric oxide synthase isoforms associated with differences in severity of cardiopulmonary diseases: cleavage of proteins with aspartate vs. glutamate at position 298. Proc. Natl. Acad. Sci. USA., 6: 2832-2835.
27. Wang XL, Mahaney MC, Sim AS, Wang J, Blangero J, Almasy L, Badenhop RB, Wilcken DE (1997). Genetic contribution of the endothelial constitutive nitric oxide synthase gene to plasma nitric oxide levels. Arterioscler Thromb Vasc Biol., 17: 3147-3153.
28. Yoshimura T, Yoshimura M, Tabata A, Shimasaki Y, Nakayama M, Miyamoto Y, Saito Y, Nakao K, Yasue H, Okamura H (2000). Association of the missense Glu298Asp variant of the endothelial nitric oxide synthase gene with severe preeclampsia. J. Soc. Gynecol. Invest., 7: 238-241.
29. Yoshimura M, Yasue H, Nakayama M, Shimasaki Y, Ogawa H, Kugiyama K, Saito Y, Miyamoto Y, Ogawa Y, Kaneshige T, Hiramatsu H, Yoshioka T, Kamitani S, Teraoka H, Nakao K (2000). Genetic risk factors for coronary artery spasm: significance of endothelial nitric oxide synthase gene T-7863C and missense Glu298Asp variants. J. Invest. Med., 48: 367-374.
30. Yoshimura T, Yoshimura M, Tabata A, Yasue H, Okamura H (2001). The missense Glu298Asp variant of the endothelial nitric oxide synthase gene is strongly associated with placental abruption. Hum. Genet., 108: 181-183.
31. Yoshimura T, Chowdhury FA, Yoshimura M, Okamura H (2003). Genetic and environmental contributions to severe preeclampsia; lack of association with the endothelial nitric oxide synthase Glu298Asp variant in a developing country. Gynecol. Obstet. Invest., 56: 10-13.
32. Yu CK, Casas JP, Savvidou MD, Sahemey MK, Nicolaides KH, Hingorani AD (2006). Endothelial nitric oxide synthase gene polymorphism (Glu298Asp) and development of pre-eclampsia: a case-control study and a meta-analysis. BMC Pregnancy Childbirth, 16: 6-7.