Genetic risk factors for coronary artery spasm: Significance of endothelial nitric oxide synthase gene T-786→C and missense Glu298Asp variants

Journal of Investigative Medicine

Volumn 48, Issue 5, 2000, Pages 367-374

  Yoshimura, M ^a   Yasue, H ^a   Nakayama, M ^a   Shimasaki, Y ^a   Ogawa, H ^a   Kugiyama, K ^a   Saito, Y ^a   Miyamoto, Y ^a   Ogawa, Y ^a   Kaneshige, T ^a   Hiramatsu, H ^a   Yoshioka, T ^a   Kamitani, S ^a   Teraoka, H ^a   Nakao, K ^a  

^a KUMAMOTO UNIV SCHOOL OF MEDICINE   (Japan)

Author keywords

Cigarette smoking; Coronary spasm; eNOS gene; Mutation; Risk factor

Indexed keywords

ASPARTIC ACID; CYTOSINE; GLUTAMIC ACID; NITRIC OXIDE SYNTHASE; TYROSINE;

ADULT; AGED; ARTICLE; CIGARETTE SMOKING; CONTROLLED STUDY; CORONARY ARTERY SPASM; ENZYME POLYMORPHISM; FEMALE; GENETIC LINKAGE; GENETIC RISK; HUMAN; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; RISK ASSESSMENT; RISK FACTOR;

EID: 0033850271     PISSN: 17088267     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Coronary-artery spasm
2. Coronary-artery spasm and myocardial infarction
3. Coronary arterial spasm in ischemic heart disease and its pathogenesis. A review
4. Coronary artery spasm and vasoconstriction. The case for a distinction
5. Nitric oxide-mediated flow-dependent dilation is impaired in coronary arteries in patients with coronary spastic angina
6. Nitric oxide activity is deficient in spasm arteries of patients with coronary spastic angina
7. Flow-mediated, endothelium-dependent dilation of the brachial arteries is impaired in patients with coronary spastic angina
8. Coronary artery spasm: Japanese view
9. Frequency of provoked coronary arterial spasm in 1089 consecutive patients undergoing coronary arteriography
10. A missense Glu298Asp variant in the endothelial nitric oxide synthase gene is associated with coronary spasm in the Japanese
11. Association of the missense Glu298Asp mutation of the endothelial nitric oxide synthase gene with myocardial infarction
12. -786→C mutation in the 5'-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm
13. -786→C mutation of the endothelial nitric oxide synthase gene is involved in coronary spastic angina
14. A smoking-dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase gene
15. Genetic contribution of the endothelial constitutive nitric oxide synthase gene to plasma nitric oxide levels
16. Evidence of association of the eNOS gene polymorphism with plasma NO metabolite levels in humans
17. Pathophysiology and treatment of coronary arterial spasm
18. Coronary spasm: Clinical features and pathogenesis
19. Induction of coronary artery spasm by acetylcholine in patients with variant angina: Possible role of the parasympathetic nervous system in the pathogenesis of coronary artery spasm
20. Multivessel coronary spasm in patients with variant angina: A study with intracoronary injection of Acetylcholine
21. Effects of intracoronary injection of acetylcholine on coronary arterial hemodynamics and diameter
22. Sensitivity and specificity of intracoronary injection of acetylcholine for the induction of coronary artery spasm
23. Estimation of linkage disequilibrium in randomly mating populations
24. Circadian variation of exercise capacity in patients with Prinzmetal's variant angina: Role of exercise-induced coronary arterial spasm
25. Endothelial nitric oxide synthase gene is positively associated with essential hypertension
26. Endothelial nitric oxide synthase as a potential susceptibility gene in the pathogenesis of emphysema in alphal-antitrypsin deficiency
27. Deficiency in nitric oxide bioactivity in epicardial coronary arteries of cigarette smokers
28. Long-term cigarette smoking impairs endothelium-dependent coronary arterial vasodilator function
29. Endothelium-dependent vasodilation in the brachial artery is impaired in smokers: Effect of vitamin C
30. Smoking is a risk factor for coronary spasm in young women
31. Cigarette smoking is a major risk factor for coronary spasm
32. Comparison of the risk factors for coronary artery spasm with those for organic stenosis in a Japanese population: Role of cigarette smoking