Endothelial nitric oxide synthase gene Glu298Asp polymorphism in patients with coronary artery disease

Annals of Saudi Medicine

Volumn 30, Issue 1, 2010, Pages 33-37

  Salimi, Saeedeh ^a,b   Firoozrai, Mohsen ^c   Zand, Hamid ^d   Nakhaee, Alireza ^a,b   Shafiee, Sayed M ^c   Tavilani, Heidar ^e   Mohebbi, Ahmad ^f  

^a IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ZAHEDAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^e HAMADAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^f IRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE;

ADULT; ANGIOCARDIOGRAPHY; ARTICLE; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY BLOOD VESSEL; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HUMAN; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR;

ANALYSIS OF VARIANCE; ARGININE; CASE-CONTROL STUDIES; CONFIDENCE INTERVALS; CORONARY ARTERY DISEASE; ENDOTHELIUM, VASCULAR; FEMALE; HUMANS; IRAN; LOGISTIC MODELS; MALE; MIDDLE AGED; NITRIC OXIDE SYNTHASE TYPE III; ODDS RATIO; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RISK FACTORS;

EID: 77249146428     PISSN: 02564947     EISSN: 09754466     Source Type: Journal    
DOI: 10.5144/0256-4947.59370     Document Type: Article

References (29)

1. Moncada S, Palmer RM, Higgs EA. Nitric oxide: physiology, pathophysiology, and pharmacology. Pharmacol Rev 1991;43:109-142
2. Wang Y, Marsden PA. Nitric oxide synthase: biochemical and molecular regulation. Curr Opin Nephrol Hypertens 1995;4:12-22.
3. Waldman SA, Murad F. Biochemical mechanisms underlying vascular smooth muscle relaxation: the guanylate cyclase-cyclic GMP system. J Cardiovasc Pharmacol 1988;12:S115-8.
4. Marsden PA, Heng HH, Scherer SW, Stewart RJ, Hall AV, Shi XM, et al. Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. J Biol Chem 1993;268:17478-17488
5. Nadaud S, Bonnardeaux A, Lathrop M, Soubrier F. Gene structure, polymorphism and mapping of the human endothelial nitric oxide synthase gene. Biochem Biophys Res Commun 1994;198:1027-1033
6. Yoon S, Moon J, Shin C, Kim E, Jo SA, Jo I. Smoking status-dependent association of the 27-bp repeat polymorphism in intron 4 of endothelial nitric oxide synthase gene with plasma nitric oxide concentrations. Clin Chim Acta 2002;324:113-120
7. Kone BC. Molecular biology of natriuretic peptides and nitric oxide synthase. Cardiovasc Res 2002;51:429-441
8. Yoshimura M, Yasue H, Nakayama M, Shimasaki Y, Sumida H, Sugiyama S, et al. A missense Glu298Asp variant in the endothelial nitric oxide synthase gene is associated with coronary spam in the Japanese. Hum Genet 1998;103:65-69 (Pubitemid 28398388)
9. Wang XL, Sim AS, Badenhop RF, McCredie RM, Wilcken DE. A smoking-dependent risk of coronaryartery disease associated with a polymorphism of the endothelial nitric oxide synthase gene. Nat Med 1996;2:41-45
10. Hingorani AD, Liang CF, Fatibene J, Lyon A, Monteith S, Parsons A, et al. A common variant of the endothelial nitric oxide synthase (Glu298Asp) is a major risk factor for coronary artery disease in the UK. Circulation 1998;100:1515-1520
11. Yashimura M, Yasue H, Nakayama M, Kujiyama Y. Risk factors for Coronary artery spam: significance of endothelial nitric oxide synthase gene T-786C and missence Glu298Asp variants. J Invest Med 2000;48:367-374
12. Nakayama M, Yasue H, Yoshimura M, Shimasaki Y, Kugiyama K, Ogawa H, et al. T786C mutation in the 5́-flanking region of the endothelial nitric oxide synthase gene is associated with coronary spasm. Circulation 1999;99:2864-2870
13. Stangl K, Cascorbi I, Laule M, Klein T, Stangl V, Rost S, et al. High CA repeat numbers in intron 13 of the endothelial nitric oxide synthase gene and increased risk of coronary artery disease. Pharmacogenetics 2000;10:133-140
14. Colombo MG, Andreassi MG, Paradossi U, Botto N, Manfredi S, Masetti S, et al. Evidence for association of a common variant of the endothelial nitric oxide synthase gene (Glu298→Asp polymorphism) to the presence, extent, and severity of coronary artery disease. Heart 2002;87:525-528
15. Hibi K, Ishigami T, Tamura K, Mizushima S, Nyui N, Fujita T, et al. Endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction. Hypertension 1998;32:521-526
16. Umbach DM, Weinberg CR. Designing and analyzing case-control studies to exploit independence of genotype and exposure. Stat Med 1997;16:1731-1743
17. Wang XL, Sim AS, Badenhop RF, McCredie RM, Wilcken DE. A smoking-dependent risk of coronary artery disease associated with a polymorphism of the endothelial nitric oxide synthase gene. Nat Med 1996;2:41-45
18. Loscalzo J, Welch G. Nitric oxide and its role in cardiovascular system. Prog Cardiovasc Dis 1995;38:87-104.
19. Cai H, Wilcken DE, Wang XL. The Glu298Asp mutation at exon 7 of the endothelial nitric oxide synthase gene and coronary artery disease. J Mol Med 1998;77:511-514
20. Lembo G, De Luca N, Battagli C, Iovino G, Aretini A, Musicco M, et al. A common variant of endothelial nitric oxide synthase (Glu298Asp) is an independent risk factor for carotid atherosclerosis. Stroke 2001;32:735-740
21. Gardemann A, Lohre J, Cayci S, Katz N, Tillmanns H, Haberbosch W. The T allele of the missense Glu(298)Asp endothelial nitric oxide synthase gene polymorphism is associated with coronary heart disease in younger individuals with high atherosclerotic risk profile. Atherosclerosis 2002;160:167-175
22. Nassar BA, Bevin LD, Johnstone DE, O'neill BJ, Bata IR, Kirkland SA, et al. Relationship of the Glu298Asp polymorphism of the endothelial nitric oxide synthase gene and early-onset coronary artery disease. Am Heart J 2001;142:586-589
23. Schmoelzer I, Renner W, Paulweber B, Malaimare L, Iglseder B, Schmid P, et al. Lack of association of the Glu298Asp polymorphism of endothelial nitric oxide synthase with manifest coronary artery disease, carotid atherosclerosis and forearm vascular reactivity in two Austrian populations. Eur J Clin Invest 2003;33:191-198
24. Jaramillo PC, Muñoz MA, Lanas MC, Lanas ZF, Salazar LA. Endothelial nitric oxide synthase G894T gene polymorphism in Chilean subjects with coronary artery disease and controls. Clin Chim Acta 2006;371:102-106
25. Kerkeni M, Addad F, Chauffert M, Myara A, Ben Farhat M, Miled A, et al. Hyperhomocysteinemia, endothelial nitric oxide synthase polymorphism, and risk of coronary artery disease. Clin Chem 2006;52:53-58
26. Cam SF, Sekuri C, Tengiz I, Ercan E, Sagcan A, Akin M, et al. The G894T polymorphism on endothelial nitric oxide synthase gene is associated with premature coronary artery disease in a Turkish population. Thromb Res 2005;116:287-292
27. Berdeli A, Sekuri C, Sirri Cam F, Ercan E, Sagcan A, Tengiz I, et al. Association between eNOS(Glu298Asp) and the RAS genes polymorphisms and premature coronary artery disease in a Turkish population. Clin Chim Acta 2005;351:87-94. (Pubitemid 39563560)
28. Salimi S, Firoozrai M, Nourmohammadi I, Shabani M, Mohebbi A. Endothelial nitric oxide synthase gene intron4 VNTR polymorphism in patients with coronary artery disease in Iran. Indian J Med Res 2006;124:683-688 (Pubitemid 46592109)
29. Srivastava K, Biswas UK, Narang R, Varghese JJ, Das N. Prevalence of NOS3 Glu298Asp polymorphism in healthy volunteers from a region of Northern India. Community Genet 2005;8:180-183