메뉴 건너뛰기




Volumn 10, Issue , 2011, Pages

Increased interleukin-10 and interferon-levels in Plasmodium vivax malaria suggest a reciprocal regulation which is not altered by IL-10 gene promoter polymorphism

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 4; IL10 PROTEIN, HUMAN; INTERFERON;

EID: 80052838921     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-10-264     Document Type: Article
Times cited : (61)

References (56)
  • 2
    • 4644337572 scopus 로고    scopus 로고
    • Serum levels of the proinflammatory cytokines interleukin-1 beta (IL-1), IL-6, IL-8, IL-10, tumor necrosis factor alpha, and IL-12(p70) in Malian children with severe Plasmodium falciparum malaria and matched uncomplicated malaria or healthy controls
    • DOI 10.1128/IAI.72.10.5630-5637.2004
    • Serum levels of the proinflammatory cytokines interleukin-1 beta (IL-1) IL-6, IL-8, IL-10, tumor necrosis factor alpha, and IL-12 (p70) in Malian children with severe Plasmodium falciparum malaria and matched uncomplicated malaria or healthy controls. Lyke KE, Burges R, Cissoko Y, Sangare L, Dao M, Diarra I, Kone A, Harley R, Plowe CV, Doumbo OK, Sztein MB, Infect Immun 2004 72 5630 5637 10.1128/IAI.72.10.5630-5637.2004 15385460 (Pubitemid 39303671)
    • (2004) Infection and Immunity , vol.72 , Issue.10 , pp. 5630-5637
    • Lyke, K.E.1    Burges, R.2    Cissoko, Y.3    Sangare, L.4    Dao, M.5    Diarra, I.6    Kone, A.7    Harley, R.8    Plowe, C.V.9    Doumbo, O.K.10    Sztein, M.B.11
  • 3
    • 33750625136 scopus 로고    scopus 로고
    • Human malarial disease: A consequence of inflammatory cytokine release
    • DOI 10.1186/1475-2875-5-85
    • Human malarial disease: a consequence of inflammatory cytokine release. Clark IA, Budd AC, Alleva LM, Cowden WB, Malar J 2006 5 85 10.1186/1475-2875-5- 85 17029647 (Pubitemid 44687371)
    • (2006) Malaria Journal , vol.5 , pp. 85
    • Clark, I.A.1    Budd, A.C.2    Alleva, L.M.3    Cowden, W.B.4
  • 4
    • 65349181325 scopus 로고    scopus 로고
    • The pathophysiology of vivax malaria
    • 10.1016/j.pt.2009.02.003 19349210
    • The pathophysiology of vivax malaria. Anstey NM, Russell B, Yeo TW, Price RN, Trends Parasitol 2009 25 220 227 10.1016/j.pt.2009.02.003 19349210
    • (2009) Trends Parasitol , vol.25 , pp. 220-227
    • Anstey, N.M.1    Russell, B.2    Yeo, T.W.3    Price, R.N.4
  • 7
    • 16844369607 scopus 로고    scopus 로고
    • Natural regulatory T cells in infectious disease
    • DOI 10.1038/ni1181
    • Natural regulatory T cells in infectious disease. Belkaid Y, Rouse BT, Nat Immnunol 2005 6 353 360 (Pubitemid 41716772)
    • (2005) Nature Immunology , vol.6 , Issue.4 , pp. 353-360
    • Belkaid, Y.1    Rouse, B.T.2
  • 8
    • 44449096726 scopus 로고    scopus 로고
    • IL-10: The master regulator of immunity to infection
    • 18424693
    • IL-10: The master regulator of immunity to infection. Couper KN, Blount DG, Riley EM, J Immunol 2008 180 5771 5777 18424693
    • (2008) J Immunol , vol.180 , pp. 5771-5777
    • Couper, K.N.1    Blount, D.G.2    Riley, E.M.3
  • 9
    • 77954037319 scopus 로고    scopus 로고
    • Natural Regulatory T cells in malaria: Host or parasite allies?
    • 10.1371/journal.ppat.1000771
    • Natural Regulatory T cells in malaria: host or parasite allies? Hansen DS, Schofield L, PlosS Pathog 2010 6 1000771 10.1371/journal.ppat.1000771
    • (2010) PlosS Pathog , vol.6 , pp. 51000771
    • Hansen, D.S.1    Schofield, L.2
  • 10
    • 45549097494 scopus 로고    scopus 로고
    • Immunity to malaria: More questions than answers
    • DOI 10.1038/ni.f.205, PII NI.F.205
    • Immunity to malaria: more questions than answers. Langhorne J, Ndungu FM, Sponaas AM, Marsh K, Nat Immunol 2008 9 725 732 18563083 (Pubitemid 351859155)
    • (2008) Nature Immunology , vol.9 , Issue.7 , pp. 725-732
    • Langhorne, J.1    Ndungu, F.M.2    Sponaas, A.-M.3    Marsh, K.4
  • 11
    • 0026653880 scopus 로고
    • Tumour necrosis factor-dependent parasite-killing effects during paroxysms in non-immune Plasmodium vivax malaria patients
    • 1351432
    • Tumour necrosis factor-dependent parasite-killing effects during paroxysms in non-immune Plasmodium vivax malaria patients. Karunaweera ND, Carter R, Grau GE, Kwiatkowski D, Del Giudice G, Mendis KN, Clin Exp Immunol 1992 88 499 505 1351432
    • (1992) Clin Exp Immunol , vol.88 , pp. 499-505
    • Karunaweera, N.D.1    Carter, R.2    Grau, G.E.3    Kwiatkowski, D.4    Del Giudice, G.5    Mendis, K.N.6
  • 13
    • 33645861671 scopus 로고    scopus 로고
    • Parasite density and serum cytokine levels in Plasmodium vivax malaria in Turkey
    • 10.1111/j.1365-3024.2006.00822.x 16629705
    • Parasite density and serum cytokine levels in Plasmodium vivax malaria in Turkey. Zeyrek FY, Kurcer MA, Zeyrek D, Simsek Z, Parasite Immunol 2006 28 201 207 10.1111/j.1365-3024.2006.00822.x 16629705
    • (2006) Parasite Immunol , vol.28 , pp. 201-207
    • Zeyrek, F.Y.1    Kurcer, M.A.2    Zeyrek, D.3    Simsek, Z.4
  • 14
    • 0026523620 scopus 로고
    • Dynamics of fever and serum levels of tumor necrosis factor are closely associated during clinical paroxysms in Plasmodium vivax malaria
    • 10.1073/pnas.89.8.3200 1565611
    • Dynamics of fever and serum levels of tumor necrosis factor are closely associated during clinical paroxysms in Plasmodium vivax malaria. Karunaweera ND, Grau GE, Gamage P, Carter R, Mendis KN, Proc Natl Acad Sci USA 1992 89 3200 3203 10.1073/pnas.89.8.3200 1565611
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 3200-3203
    • Karunaweera, N.D.1    Grau, G.E.2    Gamage, P.3    Carter, R.4    Mendis, K.N.5
  • 16
    • 33746128777 scopus 로고    scopus 로고
    • Clusters of cytokines determine malaria severity in Plasmodium falciparum-infected patients from endemic areas of central India
    • DOI 10.1086/504720
    • Clusters of cytokines determine malaria severity in Plasmodium falciparum-infected patients from endemic areas of central India. Prakash D, Fesel C, Jain R, Cazenave PA, Mishra GC, Pied S, J Infect Dis 2006 194 198 207 10.1086/504720 16779726 (Pubitemid 44087191)
    • (2006) Journal of Infectious Diseases , vol.194 , Issue.2 , pp. 198-207
    • Prakash, D.1    Fesel, C.2    Jain, R.3    Cazenave, P.-A.4    Mishra, G.C.5    Pied, S.6
  • 17
    • 78649736819 scopus 로고    scopus 로고
    • Interferon - Central mediator of protective immune responses against the pre-erythrocytic and blood stage of malaria
    • 10.1189/jlb.0310137 20610802
    • Interferon - central mediator of protective immune responses against the pre-erythrocytic and blood stage of malaria. McCall MBB, Sauerwein RW, J Leukoc Biol 2010 88 1131 1143 10.1189/jlb.0310137 20610802
    • (2010) J Leukoc Biol , vol.88 , pp. 1131-1143
    • McCall, M.B.B.1    Sauerwein, R.W.2
  • 18
    • 79551684627 scopus 로고    scopus 로고
    • Interferon-gamma, a valuable surrogate marker of Plasmodium falciparum pre-erythrocytic stages protective immunity
    • 10.1186/1475-2875-10-27 21303495
    • Interferon-gamma, a valuable surrogate marker of Plasmodium falciparum pre-erythrocytic stages protective immunity. Perlaza BL, Sauzet JP, Brahimi K, BenMohamed L, Druilhe P, Malar J 2011 10 27 10.1186/1475-2875-10-27 21303495
    • (2011) Malar J , vol.10 , pp. 27
    • Perlaza, B.L.1    Sauzet, J.P.2    Brahimi, K.3    Benmohamed, L.4    Druilhe, P.5
  • 19
    • 0033787711 scopus 로고    scopus 로고
    • A Single nucleotide polymorphism in the first intron of the human IFN-gamma gene: Absolute correlation with a polymorphic CA microsatellite marker of high IFN-gamma production
    • 10.1016/S0198-8859(00)00167-1 11053629
    • A Single nucleotide polymorphism in the first intron of the human IFN-gamma gene: absolute correlation with a polymorphic CA microsatellite marker of high IFN-gamma production. Pravica V, Perrey C, Stevens A, Lee JH, Hutchinson IV, Hum Immunol 2000 61 863 866 10.1016/S0198-8859(00)00167-1 11053629
    • (2000) Hum Immunol , vol.61 , pp. 863-866
    • Pravica, V.1    Perrey, C.2    Stevens, A.3    Lee, J.H.4    Hutchinson, I.V.5
  • 20
    • 34047245791 scopus 로고    scopus 로고
    • Interferon- gene+874T-A polymorphism is associated with tuberculosis and gamma interferon response
    • DOI 10.1016/j.tube.2006.10.002, PII S1472979206001077
    • Interferon-gamma gene +874T-A polymorphism is associated with tuberculosis and gamma interferon response. Sallakci N, Coskun M, Berber Z, Gürkan F, Kocamaz H, Uysal G, Bhuju S, Yavuzer U, Singh M, Yegin O, Tuberculosis 2007 87 225 230 10.1016/j.tube.2006.10.002 17276141 (Pubitemid 46551843)
    • (2007) Tuberculosis , vol.87 , Issue.3 , pp. 225-230
    • Sallakci, N.1    Coskun, M.2    Berber, Z.3    Gurkan, F.4    Kocamaz, H.5    Uysal, G.6    Bhuju, S.7    Yavuzer, U.8    Singh, M.9    Yegin, O.10
  • 21
    • 62849092522 scopus 로고    scopus 로고
    • Cytokine gene polymorphisms across tuberculosis clinical spectrum in Pakistani patients
    • 10.1371/journal.pone.0004778 19274101
    • Cytokine gene polymorphisms across tuberculosis clinical spectrum in Pakistani patients. Ansari A, Talat N, Jamil B, Hasan Z, Razzaki T, Dawood G, Hussain R, PloS One 2009 4 4778 10.1371/journal.pone.0004778 19274101
    • (2009) PloS One , vol.4 , pp. 54778
    • Ansari, A.1    Talat, N.2    Jamil, B.3    Hasan, Z.4    Razzaki, T.5    Dawood, G.6    Hussain, R.7
  • 22
    • 77953945368 scopus 로고    scopus 로고
    • IFNG +874T/A polymorphism and cytokine plasma levels are associated with susceptibility to Mycobacterium tuberculosis infection and clinical manifestation of tuberculosis
    • 10.1016/j.humimm.2010.03.008
    • IFNG +874T/A polymorphism and cytokine plasma levels are associated with susceptibility to Mycobacterium tuberculosis infection and clinical manifestation of tuberculosis. Vallinoto ACR, Graça ES, Araújo MS, Azevedo VN, Cayres-Vallinoto I, Machado LFA, Ishak MOG, Ishak R, Human Immunol 2010 71 692 696 10.1016/j.humimm.2010.03.008
    • (2010) Human Immunol , vol.71 , pp. 692-696
    • Vallinoto, A.C.R.1    Graça, E.S.2    Araújo, M.S.3    Azevedo, V.N.4    Cayres-Vallinoto, I.5    MacHado, L.F.A.6    Ishak, M.O.G.7    Ishak, R.8
  • 23
    • 57049122803 scopus 로고    scopus 로고
    • Haplotypes of IL-10 promoter variants are associated with susceptibility to severe malarial anemia and functional changes in IL-10 production
    • 10.1007/s00439-008-0578-5 18972133
    • Haplotypes of IL-10 promoter variants are associated with susceptibility to severe malarial anemia and functional changes in IL-10 production. Ouma C, Davenport GC, Were T, Otieno MF, Hittner JB, Vulule JM, Martinson J, Ong'echa JM, Ferrell RE, Perkins DJ, Hum Genet 2008 124 515 524 10.1007/s00439-008-0578-5 18972133
    • (2008) Hum Genet , vol.124 , pp. 515-524
    • Ouma, C.1    Davenport, G.C.2    Were, T.3    Otieno, M.F.4    Hittner, J.B.5    Vulule, J.M.6    Martinson, J.7    Ong'Echa, J.M.8    Ferrell, R.E.9    Perkins, D.J.10
  • 25
    • 79651468824 scopus 로고    scopus 로고
    • Cytokine gene polymorphism and Chlamydia trachomatis-specific immune responses
    • 10.1016/j.humimm.2010.12.012 21215285
    • Cytokine gene polymorphism and Chlamydia trachomatis-specific immune responses. hman H, Tiitinen A, Halttunen M, Paavonen J, Surcel HM, Hum Immunol 2011 72 278 282 10.1016/j.humimm.2010.12.012 21215285
    • (2011) Hum Immunol , vol.72 , pp. 278-282
    • Hman, H.1    Tiitinen, A.2    Halttunen, M.3    Paavonen, J.4    Surcel, H.M.5
  • 26
    • 43049101705 scopus 로고    scopus 로고
    • Interleukin-10 and Tumor Necrosis Factor- gene polymorphisms in tuberculosis
    • 10.1007/s10875-007-9155-2 18071881
    • Interleukin-10 and Tumor Necrosis Factor- gene polymorphisms in tuberculosis. Ates O, Musellim B, Ongen G, Topal-Sarikaya A, J Clin Immunol 2008 28 232 236 10.1007/s10875-007-9155-2 18071881
    • (2008) J Clin Immunol , vol.28 , pp. 232-236
    • Ates, O.1    Musellim, B.2    Ongen, G.3    Topal-Sarikaya, A.4
  • 27
    • 45449083789 scopus 로고    scopus 로고
    • Cytokine gene polymorphisms and cytokine levels in pulmonary tuberculosis
    • 10.1016/j.cyto.2008.04.011 18522869
    • Cytokine gene polymorphisms and cytokine levels in pulmonary tuberculosis. Selvaraj P, Alagarasu K, Harishankar M, Vidyarani M, Rajeswari DN, Narayanan PR, Cytokine 2008 43 26 33 10.1016/j.cyto.2008.04.011 18522869
    • (2008) Cytokine , vol.43 , pp. 26-33
    • Selvaraj, P.1    Alagarasu, K.2    Harishankar, M.3    Vidyarani, M.4    Rajeswari, D.N.5    Narayanan, P.R.6
  • 29
    • 20644435346 scopus 로고    scopus 로고
    • Association of polymorphism of IL-10 and TNF-A genes with gastric cancer in Korea
    • DOI 10.1016/j.canlet.2004.11.028, PII S0304383504008936
    • Association of polymorphism of IL-10 and TNF- genes with gastric cancer in Korea. Lee JA, Kim HY, Kim KH, Kim SM, Jang MK, Park JY, Lee JH, Kim JH, Yoo JY, Cancer Lett 2005 225 207 214 10.1016/j.canlet.2004.11.028 15978325 (Pubitemid 40835868)
    • (2005) Cancer Letters , vol.225 , Issue.2 , pp. 207-214
    • Ja, Y.L.1    Hak, Y.K.2    Kyung, H.K.3    Seong, M.K.4    Myoung, K.J.5    Joon, Y.P.6    Jin, H.L.7    Kim, J.-H.8    Jae, Y.Y.9
  • 31
    • 2142711618 scopus 로고    scopus 로고
    • Cerebral Edema and Cerebral Hemorrhages in Interleukin-10-Deficient Mice Infected with Plasmodium chabaudi
    • DOI 10.1128/IAI.72.5.3054-3058.2004
    • Cerebral edema and cerebral hemorrhages in interleukin-10-deficient mice infected with Plasmodium chabaudi. Sanni LA, Jarra W, Li C, Langhorne J, Infect Immun 2004 72 3054 3058 10.1128/IAI.72.5.3054-3058.2004 15102820 (Pubitemid 38542438)
    • (2004) Infection and Immunity , vol.72 , Issue.5 , pp. 3054-3058
    • Sanni, L.A.1    Jarra, W.2    Li, C.3    Langhorne, J.4
  • 37
    • 77649179756 scopus 로고    scopus 로고
    • A preliminary study on pro- and anti-inflammatory cytokine profiles in Plasmodium vivax patients from central zone of India
    • 10.1016/j.actatropica.2009.11.009 19958746
    • A preliminary study on pro- and anti-inflammatory cytokine profiles in Plasmodium vivax patients from central zone of India. Jain V, Singh PP, Silawat N, Patel R, Saxena A, Bharit PK, Shukla M, Biswas S, Singh N, Acta Trop 2010 113 263 268 10.1016/j.actatropica.2009.11.009 19958746
    • (2010) Acta Trop , vol.113 , pp. 263-268
    • Jain, V.1    Singh, P.P.2    Silawat, N.3    Patel, R.4    Saxena, A.5    Bharit, P.K.6    Shukla, M.7    Biswas, S.8    Singh, N.9
  • 41
    • 0030948548 scopus 로고    scopus 로고
    • Acquired immune responses to the N- and C-terminal regions of Plasmodium vivax merozoite surface protein 1 in individuals exposed to malaria
    • Acquired immune responses to the N- and C-terminal regions of Plasmodium vivax Merozoite Surface Protein 1 in individuals exposed to malaria. Soares IS, Levitus G, Souza JM, Del Portillo HA, Rodrigues MM, Infect Immun 1997 65 1606 1614 9125537 (Pubitemid 27193576)
    • (1997) Infection and Immunity , vol.65 , Issue.5 , pp. 1606-1614
    • Soares, I.S.1    Levitus, G.2    Souza, J.M.3    Del Portillo, H.A.4    Rodrigues, M.M.5
  • 43
    • 36749090145 scopus 로고    scopus 로고
    • Expression and purification of a Plasmodium vivax antigen - PvTARAg55 tryptophan- and alanine-rich antigen and its immunological responses in human subjects
    • DOI 10.1016/j.vaccine.2007.10.042, PII S0264410X07012224
    • Expression and purification of a Plasmodium vivax antigen-PvTARAg55 tryptophan- and alanine-rich antigen and its immunological responses in human subjects. Siddiqui AA, Singh N, Sharma YD, Vaccine 2007 26 96 107 10.1016/j.vaccine.2007.10.042 18054126 (Pubitemid 350213202)
    • (2007) Vaccine , vol.26 , Issue.1 , pp. 96-107
    • Siddiqui, A.A.1    Singh, N.2    Sharma, Y.D.3
  • 45
    • 79952470466 scopus 로고    scopus 로고
    • Antibody-mediated and cellular immune responses induced in naive volunteers by vaccination with long synthetic peptides derived from the Plasmodium vivax circumsporozoite protein
    • 21292876
    • Antibody-mediated and cellular immune responses induced in naive volunteers by vaccination with long synthetic peptides derived from the Plasmodium vivax circumsporozoite protein. Arévalo-Herrera M, Soto L, Perlaza BL, Céspedes N, Vera O, Lenis AM, Bonelo A, Corradin G, Herrera S, Am J Trop Med Hyg 2011 84 Suppl 2 35 42 21292876
    • (2011) Am J Trop Med Hyg , vol.84 , Issue.SUPPL. 2 , pp. 35-42
    • Arévalo-Herrera, M.1    Soto, L.2    Perlaza, B.L.3    Céspedes, N.4    Vera, O.5    Lenis, A.M.6    Bonelo, A.7    Corradin, G.8    Herrera, S.9
  • 46
    • 37849042445 scopus 로고    scopus 로고
    • Increased circulating interleukin (IL)-23 in children with malarial anemia: In vivo and in vitro relationship with co-regulatory cytokines IL-12 and IL-10
    • 10.1016/j.clim.2007.08.007
    • Increased circulating interleukin (IL)-23 in children with malarial anemia: in vivo and in vitro relationship with co-regulatory cytokines IL-12 and IL-10. Ong'echa JM, Remo AM, Kristoff J, Hittner JB, Were T, Ouma C, Otieno RO, Vulule JM, Keller CC, Awandare GA, Perkins DJ, Clin Immun 2008 126 211 221 10.1016/j.clim.2007.08.007
    • (2008) Clin Immun , vol.126 , pp. 211-221
    • Ong'Echa, J.M.1    Remo, A.M.2    Kristoff, J.3    Hittner, J.B.4    Were, T.5    Ouma, C.6    Otieno, R.O.7    Vulule, J.M.8    Keller, C.C.9    Awandare, G.A.10    Perkins, D.J.11
  • 47
    • 0032526338 scopus 로고    scopus 로고
    • Molecular mechanisms of the induction of IL-12 and its inhibition by IL- 10
    • Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10. Aste-Amezaga M, Ma X, Sartori A, Trinchieri G, J Immunol 1998 160 5936 5944 9637507 (Pubitemid 28298054)
    • (1998) Journal of Immunology , vol.160 , Issue.12 , pp. 5936-5944
    • Aste-Amezaga, M.1    Ma, X.2    Sartori, A.3    Trinchieri, G.4
  • 49
    • 33748032407 scopus 로고    scopus 로고
    • Acquisition of hemozoin by monocytes down-regulates interleukin-12 p40 (IL-12p40) transcripts and circulating IL-12p70 through an IL-10-dependent mechanism: In vivo and in vitro findings in severe malarial anemia
    • DOI 10.1128/IAI.00843-06
    • Acquisition of hemozoin by monocytes down-regulates interleukin-12 p40 (Il-12p40) transcripts and circulating IL-12p70 through an IL-10-dependent mechanism: in vivo and in vitro findings in severe malarial anemia. Keller CC, Yamo O, Ouma C, Ong'echa JM, Ounah D, Hittner JB, Vulule JM, Perkins DJ, Infect Immun 2006 74 5249 5260 10.1128/IAI.00843-06 16926419 (Pubitemid 44300444)
    • (2006) Infection and Immunity , vol.74 , Issue.9 , pp. 5249-5260
    • Keller, C.C.1    Yamo, O.2    Ouma, C.3    Ong'echa, J.M.4    Ounah, D.5    Hittner, J.B.6    Vulule, J.M.7    Perkins, D.J.8
  • 50
    • 4844223378 scopus 로고    scopus 로고
    • Does malaria suffer from lack of memory?
    • DOI 10.1111/j.0105-2896.2004.00181.x
    • Does malaria suffer from lack of memory. Struik SS, Riley EM, Immunol Rev 2004 201 268 290 10.1111/j.0105-2896.2004.00181.x 15361247 (Pubitemid 39318458)
    • (2004) Immunological Reviews , vol.201 , pp. 268-290
    • Struik, S.S.1    Riley, E.M.2
  • 52
    • 38949148275 scopus 로고    scopus 로고
    • Alleles -308A and -1031C in the TNF- gene promoter do not increase the risk but associated with circulating levels of TNF- and clinical features of vivax malaria in Indian patients
    • DOI 10.1016/j.molimm.2007.10.002, PII S0161589007007912
    • Alleles -308A and -1031C in the TNF- gene promoter do not increase the risk but associated with circulating levels of TNF- and clinical features of vivax malaria in Indian patients. Sohail M, Kaul A, Bali P, Raziuddin M, Singh MP, Singh OP, Dash AP, Adak T, Mol Immunol 2008 45 1682 1692 10.1016/j.molimm.2007.10.002 17996942 (Pubitemid 351227404)
    • (2008) Molecular Immunology , vol.45 , Issue.6 , pp. 1682-1692
    • Sohail, M.1    Kaul, A.2    Bali, P.3    Raziuddin, M.4    Singh, M.P.5    Singh, O.P.6    Dash, A.P.7    Adak, T.8
  • 54
    • 0033031984 scopus 로고    scopus 로고
    • Polymorphic haplotypes of the interleukin-10 5'-flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis
    • DOI 10.1002/1529-0131(199906)42:6<1101::AID-ANR6>3.0.CO;2-Y
    • Polymorphic haplotypes of the interleukin-10 5' flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis. Crawley E, Kay R, Sillibourne J, Patel P, Hutchinson I, Woo P, Arthritis Rheum 1999 42 1101 1108 10.1002/1529-0131(199906)42:6<1101::AID-ANR6>3.0.CO;2-Y 10366102 (Pubitemid 29268946)
    • (1999) Arthritis and Rheumatism , vol.42 , Issue.6 , pp. 1101-1108
    • Crawley, E.1    Kay, R.2    Sillibourne, J.3    Patel, P.4    Hutchinson, I.5    Woo, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.