Determining allosteric modulator mechanism of action: Integration of radioligand binding and functional assay data

Methods in Molecular Biology

Volumn 746, Issue , 2011, Pages 195-209

  Langmead, Christopher J ^a  

^a Heptares Therapeutics Ltd   (United Kingdom)

Author keywords

Affinity; Allosteric; Binding; Efficacy; Orthosteric; Potency

Indexed keywords

G PROTEIN COUPLED RECEPTOR; RADIOLIGAND; GUANOSINE TRIPHOSPHATE; LIGAND; MUSCARINIC RECEPTOR;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; LIGAND BINDING; PRIORITY JOURNAL; ALLOSTERISM; BINDING SITE; BIOLOGICAL MODEL; METABOLISM; PROTEIN BINDING; RADIOASSAY;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; GUANOSINE TRIPHOSPHATE; LIGANDS; MODELS, BIOLOGICAL; PROTEIN BINDING; RADIOLIGAND ASSAY; RECEPTORS, MUSCARINIC;

EID: 80052817143     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-126-0_10     Document Type: Article

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