Surgical treatment of male infertility in the era of intracytoplasmic sperm injection-new insights

Clinics

Volumn 66, Issue 8, 2011, Pages 1463-1477

  Esteves, Sandro C ^a   Miyaoka, Ricardo ^a   Agarwal, Ashok ^b  

^a ANDROFERT Andrology and Human Reproduction Clinic   (Brazil)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Infertility; Male; Review; Sperm retrieval; Surgery

Indexed keywords

EJACULATORY DUCT; HUMAN; MALE; MALE INFERTILITY; MICROSURGERY; PROGNOSIS; REVIEW; VARICOCELE; VASOVASOSTOMY;

EJACULATORY DUCTS; HUMANS; INFERTILITY, MALE; MALE; MICROSURGERY; PROGNOSIS; VARICOCELE; VASOVASOSTOMY;

EID: 80052773426     PISSN: 18075932     EISSN: None     Source Type: Journal    
DOI: 10.1590/S1807-59322011000800026     Document Type: Review

References (124)

1. Vital and Health Statistics, series 23, no. 26, CDC. http://www.cdc.gov. Acessed December 10, 2009.
2. Silber SJ, Nagy ZP, Liu J, Godoy H, Devroey P, Van Steirteghem AC. Conventional in-vitro fertilization versus intracytoplasmic sperm injection for patients requiring microsurgical sperm aspiration. Hum Reprod. 1994;9:1705-9.
3. Devroey P, Liu J, Nagy Z, Goossens A, Tournaye H, Camus M, et al. Pregnancies after testicular extraction (TESE) and intracytoplasmic sperm injection (ICSI) in non-obstructive azoospermia. Hum Reprod. 1995;10:1457-60.
4. Schlegel PN. Testicular sperm extraction: microdissection improves sperm yield with minimal tissue excision. Hum Reprod. 1999;14:131-5, doi: 10.1093/humrep/14.1.131.
5. a. ed Porto Alegre, RS: Artmed Editora; 2009:470-500.
6. Libman J, Jarvi K, Lo K, Zini A. Beneficial effect of microsurgical varicocelectomy is superior for men with bilateral versus unilateral repair. J Urol. 2006;176:2602-5, doi: 10.1016/j.juro.2006.07.161.
7. Gat Y, Bachar GN, Zukerman Z, Belenky A, Gorenish M. Physical examination may miss the diagnosis of bilateral varicocele: a comparative study of 4 diagnostic modalities. J Urol. 2004;172:1414-7, doi: 10.1097/01.ju.0000138540.57137.5f.
8. Geatti O, Gasparini D, Shapiro B. A comparison of scintigraphy, thermography, ultrasound and phlebography in grading of clinical varicocele. J Nucl Med. 1991;32:2092-7.
9. Yamamoto M, Hibi H, Hirata Y, Miyake K, Ishigaki T. Effect of varicocelectomy on sperm parameters and pregnancy rate in patients with subclinical varicocele: a randomized prospective controlled study. J Urol. 1996;155:1636-8, doi: 10.1016/S0022-5347(01)66149-4.
10. Kantartzi PD, Goulis ChD, Goulis GD, Papadimas I. Male infertility and varicocele: myths and reality. Hippokratia. 2007;11:99-104.
11. Esteves SC, Glina S. Recovery of spermatogenesis after microsurgical subinguinal varicocele repair in azoospermic men based on testicular histology. Int Braz J Urol. 2005;31:541-8, doi: 10.1590/S1677-55382005000600005.
12. Weedin JW, Khera M, Lipshultz LI. Varicocele Repair in Patients with Nonobstructive Azoospermia-A Meta-Analysis. J Urol. 2010;183:2309-15, doi: 10.1016/j.juro.2010.02.012.
13. Esteves SC. Editorial comment. J Urol. 2010;183:2315, doi: 10.1016/j. juro.2010.02.2419.
14. Cayan S, Shavakhabov S, Kadioglu A. Treatment of palpable varicocele review in infertile men: a meta-analysis to define the best technique. J Androl. 2009;30:33-40, doi: 10.2164/jandrol.108.005967.
15. Sautter T, Sulser T, Suter S, Gretener H, Hauri D. Treatment of varicocele: a prospective randomized comparison of laparoscopy versus antegrade sclerotherapy. Eur Urol. 2002;41:398-400, doi: 10.1016/S0302-2838(02)00022-2.
16. Al-Kandari AM, Shabaan H, Ibrahim HM, Elshebiny YH, Shokeir AA. Comparison of outcomes of different varicocelectomy techniques: open inguinal, laparoscopic, and subinguinal microscopic varicocelectomy: a randomized clinical trial. Urology. 2007;69:417-20, doi: 10.1016/j. urology.2007.01.057.
17. Hopps CV, Lemer ML, Schlegel PN, Goldstein M. Intraoperative varicocele anatomy: a microscopic study of the inguinal versus subinguinal approach. J Urol. 2003;170:2366-70, doi: 10.1097/01.ju.0000097400.67715.f8.
18. Esteves SC, Oliveira FV, Bertolla RP. Clinical outcomes of intracytoplasmic sperm injection in infertile men with treated and untreated clinical varicocele. J Urol. 2010;184:1442-6, doi: 10.1016/j.juro.2010.06.004.
19. Belker AM, Thomas AJ Jr, Fuchs EF, Konnak JW, Sharlip ID. Results of 1469 microsurgical vasectomy reversals by the Vasovasostomy Study Group. J Urol. 1991;145:505-11.
20. Vasectomia no Brasil. Veja online; http://veja.abril.com.br/041000/p_084.html. Accessed October 3rd, 2010.
21. Lipshultz LI, Rumohr JA, Bennet RC. Techniques for Vasectomy Reversal. Urol Clin N Am. 2009;36:375-82, doi: 10.1016/j.ucl.2009.05.011.
22. Parekattil SJ, Kuang W, Agarwal A, Thomas AJ. Model to predict if a vasoepididymostomy will be required for vasectomy reversal. J Urol. 2005;173:1681-4, doi: 10.1097/01.ju.0000154608.08496.f2.
23. Hernandez J, Sabanegh ES. Repeat vasectomy reversal after initial failure. J Urol. 1999;161:1153-6, doi: 10.1016/S0022-5347(01)61616-1.
24. Boorjian S, Lipkin M, Goldstein M. The impact of obstructive interval and sperm granuloma on outcome of vasectomy reversal. J Urol. 2004;171:304-6, doi: 10.1097/01.ju.0000098652.35575.85.
25. Carbone DJ Jr, Shah A, Thomas AJ Jr, Agarwal A. Partial obstruction, not antisperm antibodies, causing infertility after vasovasostomy. J Urol. 1998;159:827-30, doi: 10.1016/S0022-5347(01)63744-3.
26. Chawla A, O'Brien J, Lisi M, Zini A, Jarvi K. Should all urologists performing vasectomy reversal be able to perform vasoepididymostomy if required? J Urol. 2004;172:1048-50, doi: 10.1097/01.ju.0000135118.43383.b1.
27. Schiff J, Chan P, Li PS, Finkelberg S, Goldstein M. Outcome and late failures compared in 4 techniques of microsurgical vasoepididymostomy in 153 consecutive men. J Urol. 2005;174:651-5, doi: 10.1097/01.ju.0000165573.53109.92.
28. st ed. New York, NY: WB Saunders Co., 1995:67-76.
29. st ed. New York, NY: WB Saunders Co, 1995:61-76.
30. st ed. New York, NY: WB Saunders Co, 1995:46-60.
31. Fleming C. Robot-assisted vasovasostomy. Urol Clin N Am. 2004;31:769-772, doi: 10.1016/j.ucl.2004.07.001.
32. Parekattil SJ, Cohen MS. Robotic surgery in male infertility and chronic orchialgia. Curr Opin Urol. 2010;20:75-79, doi: 10.1097/MOU. 0b013e3283337aa0.
33. Boyle KE, Thomas AJ Jr, Marmar JL, Hirshberg S, Belker AM, Jarow JP. Sperm harvesting and cryopreservation during vasectomy reversal is not cost effective. Fertil Steril. 2006;85:961-4, doi: 10.1016/j.fertnstert.2005.09.031.
34. Silber S. Microscopic vasoepididymostomy: specific microanastomosis to the epididymal tubule. Fertil Steril. 1978;30:565-71.
35. Thomas AJ Jr. Vasoepididymostomy. Urol Clin North Am. 1987;14:527-38.
36. Jee SH, Hong YK. One-layer vasovasostomy: microsurgical versus loupe-assisted. Fertil Steril. 2010;94:2308-11, doi: 10.1016/j.fertnstert.2009.12.013.
37. Netto NR Jr, Esteves SC, Neves PA. Transurethral resection of partially obstructed ejaculatory ducts: seminal parameters and pregnancy outcomes according to the etiology of obstruction. J Urol. 1998;159:2048-53, doi: 10.1016/S0022-5347(01)63243-9.
38. Meacham RB, Hellerstein DK, Lipshultz LI. Evaluation and treatment of ejaculatory duct obstruction in the infertile male. Fertil Steril. 1993;59:393-7.
39. Carter SS, Shinohara K, Lipshultz LI. Transrectal ultrasonography in disorders of the seminal vesicles and ejaculatory ducts. Urol Clin N Am. 1989;16:773-90.
40. Hellerstein DK, Meacham RB, Lipshultz LI. Transrectal ultrasound and partial ejaculatory duct obstruction in male infertility. Urology. 1992;39:449-52, doi: 10.1016/0090-4295(92)90245-R.
41. Jones TR, Zagoria RJ, Jarow JP. Transrectal US-guided seminal vesiculography. Radiology. 1997;205:276-8.
42. Jarow JP, Espeland MA, Lipshultz LI. Evaluation of the azoospermic patient. J Urol. 1989;142:62-5.
43. Farley S, Barnes R. Stenosis of ejaculatory ducts treated by endoscopic resection. J Urol. 1973;109:664-6.
44. Craft I, Tsirigotis M, Bennett V, Taranissi M, Khalifa Y, Hogewind G, et al. Percutaneous epididymal sperm aspiration and intracytoplasmic sperm injection in the management of infertility due to obstructive azoospermia. Fertil Steril. 1995;63:1038-42.
45. Craft I, Tsirigotis M. Simplified recovery, preparation and cryopreservation of testicular spermatozoa. Hum Reprod. 1995;10:1623-7.
46. Okada H, Dobashi M, Yamazaki T, Hara I, Fujisawa M, Arakawa S, et al. Conventional versus microdissection testicular sperm extraction for nonobstructive azoospermia. J Urol. 2002;168:1063-7, doi: 10.1016/ S0022-5347(05)64575-2.
47. Tsujimura A, Matsumiya K, Miyagawa Y, Tohda A, Miura H, Nishimura K, Koga M, et al. Conventional multiple or microdissection testicular sperm extraction: a comparative study. Hum Reprod. 2002;17:2924-29, doi: 10.1093/humrep/17.11.2924.
48. Ramasamy R, Lin K, Gosden LV, Rosenwaks Z, Palermo GD, Schlegel PN. High serum FSH levels in men with nonobstructive azoospermia does not affect success of microdissection testicular sperm extraction. Fertil Steril. 2009;92:590-3, doi: 10.1016/j.fertnstert.2008.07.1703.
49. Esteves SC, Verza S Jr, Gomes AP. Successful retrieval of testicular spermatozoa by microdissection (micro-TESE) in nonobstructive azoospermia is related to testicular histology. Fertil Steril. 2006;86:S354, doi:10.1016/j.fertnstert.2006.07.966.
50. Schlegel PN. Causes of azoospermia and their management. Reprod Fertil Dev. 2004;16:561-72, doi: 10.1071/RD03087.
51. Sharlip ID, Jarow J, Belker AM, Damewood M, Howards SS, Lipshultz LI, et al. Report on Evaluation of the Azoospermic Male. AUA Best Practice Policy and ASRM Practice Committee Report. American Urological Association, April 2001.
52. Esteves SC, Verza S, Prudencio C, Seol B. Sperm retrieval rates (SRR) in nonobstructive azoospermia (NOA) are related to testicular histopathology results but not to the etiology of azoospermia. Fertil Steril. 2010;94(Suppl):S132, doi: 10.1016/j.fertnstert.2010.07.532.
53. Male Infertility Best Practice Policy Committee of the American Urological Association; Practice Committee of the American Society for Reproductive Medicine. Report on evaluation of the azoospermic male. Fertil Steril. 2006;86(Suppl 1):S210-215.
54. De Braekeleer M, Dao TN. Cytogenetic studies in male infertility: a review. Hum Reprod. 1991;6:245-50.
55. Brandell RA, Mielnik A, Liotta D, Ye Z, Veeck LL, Palermo GD, et al. AZFb deletions predict the absence of spermatozoa with testicular sperm extraction: preliminary report of a prognostic genetic test. Hum Reprod. 1998;13:2812-5.
56. Hopps CV, Mielnik A, Goldstein M, Palermo GD, Rosenwaks Z, Schlegel PN. Detection of sperm in men with Y chromosome microdeletions of the AZFa, AZFb and AZFc regions. Hum Reprod. 2003;18:1660-5, doi: 10.1093/humrep/deg348.
57. Cocuzza M, Pagani R, Coelho R, Srougi M, Hallak J. The systematic use of intraoperative vascular Doppler ultrasound during microsurgical subinguinal varicocelectomy improves precise identification and preservation of testicular blood supply. Fertil Steril. 2010;93:2396-9, doi: 10.1016/j.fertnstert.2009.01.088.
58. Schlesinger MH, Wilets IF, Nagler HM. Treatment outcome after varicocelectomy. A critical analysis. Urol Clin North Am. 1994;21:517-29.
59. Shindel AW, Yan Y, Naughton CK. Does the number and size of veins ligated at left-sided microsurgical subinguinal varicocelectomy affect semen analysis outcomes? Urology. 2007;69:1176-80, doi: 10.1016/j. urology.2007.01.086.
60. Colpi GM, Carmignani L, Nerva F, Piediferro G, Castiglioni F, Grugnetti C, et al. Surgical treatment of varicocele by a subinguinal approach combined with antegrade intraoperative sclerotherapy of venous vessels. BJU Int. 2006;97:142-5, doi: 10.1111/j.1464-410X.2006.05915.x.
61. Zini A, Blumenfeld A, Libman J, Willis J. Beneficial effect of microsurgical varicocelectomy on human sperm DNA integrity. Hum Reprod. 2005;20:1018-21, doi: 10.1093/humrep/deh701.
62. Moskovtsev SI, Lecker I, Mullen JB, Jarvi K, Willis J, White J, et al. Cause-specific treatment in patients with high sperm DNA damage resulted in significant DNA improvement. Syst Biol Reprod Med. 2009;55:109-15, doi: 10.1080/19396360902787944.
63. Kondo Y, Ishikawa T, Yamaguchi K, Fujisawa M. Predictors of improved seminal characteristics by varicocele repair. Andrologia. 2009;41:20-3, doi: 10.1111/j.1439-0272.2008.00882.x.
64. Cocuzza M, Cocuzza MA, Bragais FM, Agarwal A. The role of varicocele repair in the new era of assisted reproductive technology. Clinics. 2008;63:395-404, doi: 10.1590/S1807-59322008000300018.
65. Zheng YQ, Gao X, Li ZJ, Yu YL, Zhang ZG, Li W. Efficacy of bilateral and left varicocelectomy in infertile men with left clinical and right subclinical varicoceles: a comparative study. Urology. 2009;73:1236-40, doi: 10.1016/j.urology.2008.11.050.
66. Elbendary MA, Elbadry AM. Right subclinical varicocele: how to manage in infertile patients with clinical left varicocele? Fertil Steril. 2009;92:2050-3, doi: 10.1016/j.fertnstert.2009.05.069.
67. The Male Infertility Best Practice Policy Committee of the American Urological Association; Practice Committee of the American Society for Reproductive Medicine. Report on varicocele and infertility. Fertil Steril 2004;82:S142-5.
68. th, 2011).
69. th, 2011).
70. Marmar JL, Agarwal A, Prabakaran S, Agarwal R, Short RA, Benoff S, et al. Reassessing the value of varicocelectomy as a treatment for male subfertility with a new meta-analysis. Fertil Steril. 2007;88:639-48, doi:10.1016/j.fertnstert.2006.12.008.
71. nd ed. Cambridge: Cambridge University Press 1987;80p.
72. rd ed. Cambridge: Cambridge University Press 1992;107p.
73. th ed. Cambridge: Cambridge University Press 1999;128p.
74. th ed. Geneva: WHO press, 2010, 287p.
75. Agarwal A, Deepinder F, Cocuzza M, Agarwal R, Short RA, Sabanegh E, et al. Efficacy of Varicocelectomy in Improving Semen Parameters: New Meta-analytical Approach. Urology. 2007;70:532-8.
76. Mori MM, Bertolla RP, Fraietta R, Ortiz V, Cedenho AP. Does varicocele grade determine extent of alteration to spermatogenesis in adolescents? Fertil Steril. 2008;90:1769-73, doi: 10.1016/j.fertnstert.2007.09.052.
77. Gorelick JI, Goldstein M. Loss of fertility in men with varicocele. Fertil Steril 1993;59:613-6.
78. Witt MA, Lipshultz LI. Varicocele: a progressive or static lesion? Urology. 1993;42:541-3, doi: 10.1016/0090-4295(93)90268-F.
79. Matkov TG, Zenni M, Sandlow J, Levine LA. Preoperative semen analysis as a predictor of seminal improvement following varicocelectomy. Fertil Steril. 2001;75:63-68, doi: 10.1016/S0015-0282(00)01644-7.
80. Smit M, Romijn JC, Wildhagen MF, Veldhoven JL, Weber RF, Dohle GR. Decreased sperm DNA fragmentation after surgical varicocelectomy is associated with increased pregnancy rate. J Urol. 2010;183:270-4, doi: 10.1016/j.juro.2009.08.161.
81. Jeng SY, Wu SM, Lee JD. Cadmium accumulation and metallothionein overexpression in internal spermatic vein of patients with varicocele. Urology. 2009;73:1231-5, doi: 10.1016/j.urology.2009.01.008.
82. Verza S Jr, Esteves SC. Sperm defect severity rather than sperm source is associated with lower fertilization rates after intracytoplasmic sperm injection. Int Braz J Urol. 2008,34:49-56.
83. Schlegel PN, Kaufmann J. Role of varicocelectomy in men with nonobstructive azoospermia. Fertil Steril. 2004;81:1585-8, doi: 10.1016/ j.fertnstert.2003.10.036.
84. Inci K, Hascicek M, Kara O, Dikmen AV, Gürgan T, Ergen A. Sperm retrieval and intracytoplasmic sperm injection in men with nonobstructive azoospermia, and treated and untreated varicocele. J Urol. 2009;182:1500-5, doi: 10.1016/j.juro.2009.06.028.
85. Chan PT, Goldstein M. Superior outcomes of microsurgical vasectomy reversal in men with the same female partners. Fertil Steril. 2004;81:1371-4, doi: 10.1016/j.fertnstert.2003.09.066.
86. Kolletis PN, Burns JR, Nangia AK, et al. Outcomes for vasovasostomy performed when only sperm parts are present in the vasal fluid. J Androl. 2006;27:565-7, doi: 10.2164/jandrol.05190.
87. Berger RE. Triangulation end-to-side vasoepididymostomy. J Urol. 1998;159:1951-3, doi: 10.1016/S0022-5347(01)63205-1.
88. Marmar JL. Modified vasoepididymostomy with simultaneous double needle placement, tubulotomy and tubular invagination. J Urol. 2000;163:483-6, doi: 10.1016/S0022-5347(05)67907-4.
89. Chan PT, Brandell RA, Goldstein M. Prospective analysis of outcomes after microsurgical intussusceptions vasoepididymostomy. BJU Int. 2005;96:598-601, doi: 10.1111/j.1464-410X.2005.05691.x.
90. Gerrard ER Jr, Sandlow JI, Oster RA, Burns JR, Box LC, Kolettis PN. Effect of female partner age on pregnancy rates after vasectomy reversal. Fertil Steril. 2007;87:1340-4, doi: 10.1016/j.fertnstert.2006.11.038.
91. Bolduc S, Fischer MA, Deceuninck G, Thabet M. Factors predicting overall success: a review of 74 microsurgical vasovasostomies. Can Urol Assoc J. 2007;1:388-91.
92. Marmar JL, Sharlip I, Goldstein M. Results of vasovasostomy or vasoepididymostomy after failed percutaneous epididymal sperm aspirations. J Urol. 2008;179:1506-9, doi: 10.1016/j.juro.2007.11.050.
93. Kolettis PN. Restructuring Reconstructive Techniques-Advances in Reconstructive Techniques. Urol Clin N Am. 2008;35:229-34, doi: 10.1016/j.ucl.2008.01.016.
94. Ho KL, Witte MN, Bird ET, Hakim S. Fibrin glue assisted 3-suture vasovasostomy. J Urol. 2005;174:1360-3, doi: 10.1097/01.ju.0000173941.87775.35.
95. Vrijhof EJ, De Bruine A, Zwinderman AH, Lycklamà Nijeholt AA, Koole LH. The use of newly designed nonabsorbable polymeric stent in reconstructing the vas deferens: a feasibility study in New Zealand white rabbits. BJU Int. 2005;95:1081-5, doi: 10.1111/j.1464-410X.2005.05471.x.
96. Parekattil SJ, Atalah HN, Cohen MS. Video technique for human robotassisted microsurgical vasovasostomy. J Endourol. 2010;24:511-4, doi:10.1089/end.2009.0235.
97. Schiff J, Li PS, Goldstein M. Robotic microsurgical vasovasostomy and vasoepididymostomy in rats. Int J Med Robot. 2005;1:122-126.
98. Eisenberg ML, Walsh TJ, Garcia MM, Shinohara K, Turek PJ. Ejaculatory duct manometry in normal men and in patients with ejaculatory duct obstruction. J Urol. 2008;180:255-60, doi: 10.1016/j.juro.2008.03.019.
99. Orhan I, Duksal I, Onur R, Balci TA, Poyraz K, Firdolas F, et al. Technetium Tc 99m sulphur colloid seminal vesicle scintigraphy: a novel approach for the diagnosis of the ejaculatory duct obstruction. Urology. 2008;71:672-6, doi: 10.1016/j.urology.2007.11.103.
100. Onur MR, Orhan I, Firdolas F, Onur R, Kocakoç E. Clinical and radiological evaluation of ejaculatory duct obstruction. Arch Androl. 2007;53:179-86, doi: 10.1080/01485010701426448.
101. Lawler LP, Cosin O, Jarow JP, Kim HS. Transrectal US-guided seminal vesiculography and ejaculatory duct recanalization and balloon dilation for treatment of chronic pelvic pain. J Vasc Interv Radiol. 2006;17:169-73, doi: 10.1097/01.RVI.0000186956.00155.26.
102. Manohar T, Ganpule A, Desai M. Transrectal ultrasound-and fluoroscopic-assisted transurethral incision of ejaculatory ducts: a problem-solving approach to nonmalignant hematospermia due to ejaculatory duct obstruction. Endourol. 2008;22:1531-5, doi: 10.1089/ end.2007.0415.
103. Van Peperstraten A, Proctor ML, Johnson NP, Philipson G. Techniques for surgical retrieval of sperm prior to ICSI for azoospermia. Cochrane Database Syst Rev. 2006;3:CD002807.
104. Male Infertility Best Practice Policy Committee of the American Urological Association; Practice Committee of the American Society for Reproductive Medicine. Report on the management of infertility due to obstructive azoospermia. Fertil Steril. 2008;90(Suppl. 3):S121-24.
105. Nicopoullos JD, Gilling-Smith C, Almeida PA, Norman-Taylor J, Grace I, Ramsay JW. Use of surgical sperm retrieval in azoospermic men: a meta-analysis. Fertil Steril. 2004;82:691-701, doi: 10.1016/j.fertnstert.2004.02.116.
106. Esteves SC, Verza S, Prudencio C, Seol B. Success of percutaneous sperm retrieval and intracytoplasmic sperm injection (ICSI) in obstructive azoospermic (OA) men according to the cause of obstruction. Fertil Steril. 2010;94(Suppl):S233, doi: 10.1016/j.fertnstert.2010.07.906.
107. Kamal A, Fahmy I, Mansour R, Serour G, Aboulghar M, Ramos L, et al. Does the outcome of ICSI in cases of obstructive azoospermia depend on the origin of the retrieved spermatozoa or the cause of obstruction? A comparative analysis. Fertil Steril. 2010;94:2135-40, doi: 10.1016/j. fertnstert.2010.01.041.
108. Hauser R, Yogev L, Paz G, Yavetz H, Azem F, Lessing JB, et al. Comparison of efficacy of two techniques for testicular sperm retrieval in nonobstructive azoospermia: multifocal testicular sperm extraction versus multifocal testicular sperm aspiration. J Androl. 2006;27:28-33, doi: 10.2164/jandrol.05055.
109. Donoso P, Tournaye H, Devroey P. Which is the best sperm retrieval technique for non-obstructive azoospermia? A systematic review. Hum Reprod Update. 2007;13:539-549, doi: 10.1093/humupd/dmm029.
110. Carpi A, Sabanegh E, Mechanick J. Controversies in the management of nonobstructive Azoospermia. Fertil Steril. 2009;91:963-970, doi: 10.1016/j.fertnstert.2009.01.083.
111. Schiff JD, Palermo GD, Veeck LL, Goldstein M, Rosenwaks Z, Schlegel PN, et al. Success of testicular sperm injection and intracytoplasmic sperm injection in men with Klinefelter syndrome. J Clin Endocrinol Metab. 2005;90:6263-7, doi: 10.1210/jc.2004-2322.
112. Ramasamy R, Yagan N, Schlegel PN. Structural and functional changes to the testis after conventional versus microdissection testicular sperm extraction. Urology. 2005;65:1190-4, doi: 10.1016/j.urology.2004.12.059.
113. Carpi A, Menchini Fabris FG, Palego P, Di Coscio G, Romani R, Nardini V, et al. Fine-needle and large needle percutaneous aspiration biopsy of the testicle in men with nonobstructive azoospermia: safety and diagnostic performance. Fertil Steril. 2005;83:1029-33, doi: 10.1016/j. fertnstert.2004.09.027.
114. Prudencio C, Seol B, Esteves SC. Reproductive potential of azoospermic men undergoing intracytoplasmic sperm injection is dependent on the type of azoospermia. Fertil Steril. 2010;94(Suppl):S232-S233, doi: 10.1016/j.fertnstert.2010.07.903.
115. Turunc T, Gul U, Haydardedeoglu B, Bal N, Kuzgunbay B, Peskircioglu L, et al. Conventional testicular sperm extraction combined with the microdissection technique in nonobstructive azoospermic patients: a prospective comparative study. Fertil Steril. 2010;94:2157-60, doi: 10.1016/j.fertnstert.2010.01.008.
116. Tesarik J. Paternal effects on cell division in the human preimplantation embryo. Reprod Biomed Online. 2005;10:370-5, doi: 10.1016/S1472-6483(10)61798-1.
117. Alukal JP, Lamb DJ. Intracytoplasmic sperm injection (ICSI)-what are the risks? Urol Clin North Am. 2008;35:277-88, doi: 10.1016/j.ucl.2008.01.004.
118. Knoester M, Helmerhorst FM, Vandenbroucke JP, van der Westerlaken LA, Walther FJ, Veen S, et al. Artificial Reproductive Techniques Follow-up Project. Cognitive development of singletons born after intracytoplasmic sperm injection compared with in vitro fertilization and natural conception. Fertil Steril. 2008;90:289-96, doi: 10.1016/j. fertnstert.2007.06.090.
119. Belva F, Henriet S, Liebaers I, et al. Medical outcome of 8-year-old singleton ICSI children and a spontaneously conceived comparison group. Hum Reprod. 2007;22:506-15, doi: 10.1093/humrep/del372.
120. Woldringh GH, Besselink DE, Tillema AH, Hendriks JC, Kremer JA. Karyotyping, congenital anomalies and follow-up of children after intracytoplasmic sperm injection with non-ejaculated sperm: a systematic review. Hum Reprod Update. 2010;16:12-9, doi: 10.1093/humupd/ dmp030.
121. Lee R, Li PS, Goldstein M, Tanrikut C, Schattman G, Schlegel PN. A decision analysis of treatments for obstructive azoospermia. Hum Reprod. 2008;23:2043-9, doi: 10.1093/humrep/den200.
122. Robb P, Sandlow JI. Cost-Effectiveness of Vasectomy Reversal. Urol Clin N Am. 2009;36:391-6, doi: 10.1016/j.ucl.2009.05.003.
123. Malizia BA, Hacker MR, Penzias AS. Cumulative live-birth rates after in vitro fertilization. N Engl J Med. 2009;360:236-43, doi: 10.1056/ NEJMoa0803072.
124. Hsieh MH, Meng MV, Turek PJ. Markov modeling of vasectomy reversal and ART for infertility: how do obstructive interval and female partner age influence cost effectiveness? Fertil Steril. 2007;88:840-6, doi:10.1016/j.fertnstert.2006.11.199.