Cadmium Accumulation and Metallothionein Overexpression in Internal Spermatic Vein of Patients With Varicocele

Urology

Volumn 73, Issue 6, 2009, Pages 1231-1235

  Jeng, Shaw Yeu ^a,b   Wu, Su Mei ^c   Lee, Jane Dar ^b,d  

^a Yuanshan Veterans Hospital   (Taiwan)

^b CENTRAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^c NATIONAL CHIAYI UNIVERSITY   (Taiwan)

^d TAICHUNG ARMED FORCES GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM; METALLOTHIONEIN;

ADULT; APOPTOSIS; ARTICLE; CLINICAL ARTICLE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; HUMAN; HYPOXIA; IMMUNOHISTOCHEMISTRY; INCISION; INFERTILITY; INGUINAL HERNIA; MALE; METAL BINDING; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SPERMATIC VEIN; VARICOCELE;

CADMIUM; HUMANS; MALE; METALLOTHIONEIN; TESTIS; VARICOCELE; VEINS; YOUNG ADULT;

EID: 67349253603     PISSN: 00904295     EISSN: 15279995     Source Type: Journal    
DOI: 10.1016/j.urology.2009.01.008     Document Type: Article

References (30)

1. Marmar J., and Benoff S. New scientific information related to varicoceles. J Urol 170 (2003) 2371-2373
2. Lee J.D., Jeng S.Y., and Lee T.H. Increased expression of hypoxia-inducible factor-1α in the internal spermatic vein of patients with varicocele. J Urol 175 (2006) 1045-1048
3. Benoff S., Hurley I.R., Barcia M., et al. A potential role for cadmium in the etiology of varicocele-associated infertility. Fertil Steril 67 (1997) 336-347
4. Benoff S., Jacob A., and Hurley I.R. Male infertility and environmental exposure to lead and cadmium. Hum Reprod Update 6 (2000) 107-121
5. Benoff S.H., Millan C., Hurley I.R., et al. Bilateral increased apoptosis and bilateral accumulation of cadmium in infertile men with left varicocele. Hum Reprod 19 (2004) 616-627
6. Wang G.W., Zhou Z., Klein J.B., et al. Inhibition of hypoxia/reoxygenation-induced apoptosis in metallothionein-overexpressing cardiomyocytes. Am J Physiol Heart Circul Physiol 280 (2001) H2292-H2299
7. Cherian M.G., Jayasurya A., and Bay B.H. Metallothioneins in human tumors and potential roles in carcinogenesis. Mutat Res 533 (2003) 201-209
8. Iguchi K., Otsuka T., Usui S., et al. Zinc and metallothionein levels and expression of zinc transporters in androgen-independent subline of LNCaP cells. J Androl 25 (2004) 154-161
9. Li X., Chen H., and Epstein P.N. Metallothionein protects islets from hypoxia and extends islet graft survival by scavenging most kinds of reactive oxygen species. J Biol Chem 279 (2004) 765-771
10. Tasci A.I., Resim S., Caskurlu T., et al. Color Doppler ultrasonography and spectral analysis of venous flow in diagnosis of varicocele. Eur Urol 39 (2001) 316-321
11. Sakamoto H., Saito K., Shichizyo T., et al. Color Doppler ultrasonography as a routine clinical examination in male infertility. Int J Urol 13 (2006) 1073-1078
12. Liguori G., Trombetta C., Garaffa G., et al. Color Doppler ultrasound investigation of varicocele. World J Urol 22 (2004) 378-381
13. Hsu H.S., Wei Y.H., Li A.F., et al. Defective mitochondrial oxidative phosphorylation in varicocele-bearing testicles. Urology 46 (1995) 545-549
14. Chang M.H., Lin H.C., and Hwang P.P. Effects of cadmium on the kinetics of calcium uptake in developing tilapia larvae, Oreochromis mossambicus. Fish Physiol Biochem 16 (1997) 459-470
15. Wu S.M., Weng C.F., Yu M.J., et al. Cadmium-inducible metallothionein in tilapia (Oreochromis mossambicus). Bull Environ Contam Toxicol 62 (1999) 758-768
16. Wu S.M., Weng C.F., Hwang J.C., et al. Metallothionein induction in early larval stages of tilapia (Oreochromis mossambicus). Physiol Biochem Zool 73 (2000) 531-537
17. Tang C.H., and Lee T.H. The novel correlation of carbonic anhydrase II and anion exchanger 1 in gills of the spotted green pufferfish, Tetraodon nigrovirids. J Exp Zool A Ecol Genet Physiol 307 (2007) 411-418
18. Benoff S., and Gilbert B.R. Varicocele and male infertility. Part I. Preface. Hum Reprod Update 7 (2001) 47-54
19. Marmar J.L. The pathophysiology of varicoceles in the light of current molecular and genetic information. Hum Reprod Update 7 (2001) 461-472
20. Rosenberger P., Khoury J., Kong T., et al. Identification of vasodilator-stimulated phosphoprotein (VASP) as an HIF-regulated tissue permeability factor during hypoxia. FASEB J 21 (2007) 2613-2621
21. Fischer S., Wobben M., Marti H.H., et al. Hypoxia-induced hyperpermeability in brain microvessel endothelial cells involves VEGF-mediated changes in the expression of zonula occludens-1. Microvasc Res 63 (2002) 70-80
22. Wojciak-Stothard B., and Leiper J. Rho GTPases and hypoxia in pulmonary vascular endothelial cells. Methods Enzymol 439 (2008) 267-283
23. Prozialeck W.C., Edwards J.R., and Woods J.M. The vascular endothelium as a target of cadmium toxicity. Life Sci 79 (2006) 1493-1506
24. Woods J.M., Leone M., Klosowska K., et al. Direct antiangiogenic actions of cadmium on human vascular endothelial cells. Toxicol In Vitro 22 (2008) 643-651
25. Yamasaki M., Nomura T., Sato F., et al. Metallothionein is up-regulated under hypoxia and promotes the survival of human prostate cancer cells. Oncol Rep 18 (2007) 1145-1153
26. Murphy B.J., Kimura T., Sato B.G., et al. Metallothionein induction by hypoxia involves cooperative interactions between metal-responsive transcription factor-1 and hypoxia-inducible transcription factor-1α. Mol Cancer Res 6 (2008) 483-490
27. Bay B.H., Jin R., and Jayasura A. Analysis of metallothionein expression in human cancers. Acta Histochem Cytochem 34 (2001) 171-176
28. Suzuki T., Umeyama T., Ohma C., et al. Immunohistochemical study of metallothionein in normal and benign prostatic hyperplasia of human prostate. Prostate 19 (1991) 35-42
29. Goyer R.A., Liu J., and Waalkes M.P. Cadmium and cancer of prostate and testis. Biometals 17 (2004) 555-558
30. Shimoda R., Achanzar W.E., Qu W., et al. Metallothionein is a potential negative regulator of apoptosis. Toxicol Sci 73 (2003) 294-300