An automation-assisted generic approach for biological sample preparation and LC-MS/MS method validation

Bioanalysis

Volumn 3, Issue 17, 2011, Pages 1975-1986

  Zhang, Jie ^a   Wei, Shimin ^a   Ayres, David W ^a   Smith, Harold T ^a   Tse, Francis L S ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHIR 265;

ANALYTIC METHOD; ARTICLE; AUTOMATION; CONTROLLED STUDY; DRUG STRUCTURE; GRAVIMETRY; HUMAN; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MATHEMATICAL ANALYSIS; MOLECULAR WEIGHT; PIPETTE; PLASMA; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

AUTOMATION; CHROMATOGRAPHY, LIQUID; DRUG DISCOVERY; HUMANS; IMIDAZOLES; MOLECULAR STRUCTURE; PLASMA; PYRIDINES; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; ROBOTICS; TANDEM MASS SPECTROMETRY;

EID: 80052733165     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.11.178     Document Type: Article

References (22)

1. Jemal M. High-throughput quantitative bioanalysis by LC-MS/MS. Biomed. Chromatogr. 14(6), 422-429 (2000).
2. Xu RN, Fan L, Rieser MJ, El-Shourbagy TA. Recent advances in high-throughput quantitative bioanalysis by LC-MS/MS. J. Pharm. Biomed. Anal. 44(2), 342-355 (2007). (Pubitemid 46880094)
3. Biddlecombe RA, Pleasance S. Automated protein precipitation by filtration in the 96-well format. J. Chromatogr. B 734(2), 257-265 (1999).
4. Kocan G, Quang C, Tang D. Evaluation of protein precipitation filter plates for high-throughput LC-MS/MS bioanalytical sample preparation. American Drug Discovery 1(3), 21-24 (2006).
5. Watt AP, Morrison D, Locker KL, Evans DC. Higher throughput bioanalysis by automation of a protein precipitation assay using a 96-well format with detection by LC-MS/MS. Anal. Chem. 72(5), 979-984 (2000). (Pubitemid 30127404)
6. O'Connor D, Clarke DE, Morrison D, Watt AP. Determination of drug concentrations in plasma by a highly automated, generic and flexible protein precipitation and liquid chromatography/ tandem mass spectrometry method applicable to the drug discovery environment. Rapid Commun. Mass Spectrom. 16(11), 1065-1071(2002). (Pubitemid 34555908)
7. Tong XS, Wang J, Zheng S, Pivnichny JV. High-throughput pharmacokinetics screen of VLA-4 antagonists by LC/MS/MS coupled with automated solid-phase extraction sample preparation. J. Pharm. Biomed. Anal. 35(4), 867-877 (2004). (Pubitemid 38757677)
8. Shou WZ, Jiang X, Beato BD, Naidong W. A highly automated 96-well solid phase extraction and liquid chromatography/ tandem mass spectrometry method for the determination of fentanyl in human plasma. Rapid Commun. Mass Spectrom. 15(7), 466-476 (2001). (Pubitemid 32294642)
9. Jemal M, Teitz D, Ouyang Z, Khan S. Comparison of plasma sample purification by manual liquid-liquid extraction, automated 96-well liquid-liquid extraction and automated 96-well solid-phase extraction for analysis by high-performance liquid chromatography with tandem mass spectrometry. J. Chromatogr. B Biomed. Sci. 732(2), 501-508 (1999). (Pubitemid 29460867)
10. Song Q, Junga H, Tang Y et al. Automated 96-well solid phase extraction and hydrophilic interaction liquid chromatography-tandem mass spectrometric method for the analysis of cetirizine (ZYRTEC) in human plasma-with emphasis on method ruggedness. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 814(1), 105-114 (2005). (Pubitemid 40017942)
11. Pucci V, Monteagudo E, Bonelli F. High sensitivity determination of valproic acid in mouse plasma using semi-automated sample preparation and liquid chromatography with tandem mass spectrometric detection. Rapid Commun. Mass Spectrom. 19(24), 3713-3718 (2005). (Pubitemid 41812679)
12. Ma J, Shi J, Le H et al. A fully automated plasma protein precipitation sample preparation method for LC-MS/MS bioanalysis. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 862(1-2), 219-226 (2008).
13. Xue YJ, Liu J, Pursley J, Unger S. A 96-well single-pot protein precipitation, liquid chromatography/tandem mass spectrometry (LC-MS/MS) method for the determination of muraglitazar, a novel diabetes drug, in human plasma. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 831(1-2), 213-222 (2006). (Pubitemid 43155798)
14. Deng Y, Wu JT, Lloyd TL, Chi CL, Olah TV, Unger SE. High-speed gradient parallel liquid chromatography-tandem mass spectrometry with fully automated sample preparation for bioanalysis: 30 seconds per sample from plasma. Rapid Commun. Mass Spectrom. 16(11), 1116-1123 (2002). (Pubitemid 34555915)
15. Wang PG, Wei JS, Kim G, Chang M, El-Shourbagy T. Validation and application of a high-performance liquid chromatography- tandem mass spectrometric method for simultaneous quantification of lopinavir and ritonavir in human plasma using semi-automated 96-well liquid-liquid extraction. J. Chromatogr. A 1130(2), 302-307 (2006). (Pubitemid 44441317)
16. Xu N, Kim GE, Gregg H et al. Automated 96-well liquid-liquid back extraction liquid chromatography-tandem mass spectrometry method for the determination of ABT-202 in human plasma. J. Pharm. Biomed. Anal. 36(1), 189-195 (2004). (Pubitemid 39209424)
17. Bolden RD, Hoke SH 2nd, Eichhold TH, McCauley-Myers DL, Wehmeyer KR. Semi-automated liquid-liquid back-extraction in a 96-well format to decrease sample preparation time for the determination of dextromethorphan and dextrorphan in human plasma. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 772(1), 1-10 (2002). (Pubitemid 34450747)
18. Palandra J, Weller D, Hudson G et al. Flexible automated approach for quantitative liquid handling of complex biological samples. Anal. Chem. 79(21), 8010-8015 (2007). (Pubitemid 350059995)
19. Licea-Perez H, Wang S, Bowen CL, Yang E. A semi-automated 96-well plate method for the simultaneous determination of oral contraceptives concentrations in human plasma using ultra performance liquid chromatography coupled with tandem mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 852(1-2), 69-76 (2007). (Pubitemid 46839209)
20. Tweed JA, Gu Z, Xu H et al. Automated sample preparation for regulated bioanalysis: an integrated multiple assay extraction platform using robotic liquid handling. Bioanalysis 2(6), 1023-1040(2010).
21. Vindigni M, Walter E, Zhang J. A semi-automated generic approach for rapid development and evaluation of sample preparation procedures. Proceedings of: the 50th ASMS Conference on Mass Spectrometry and Allied Topics. Orlando, FL, USA, 1-6 June 2002.
22. Li W, Tse FL. Dried blood spot sampling in combination with LC-MS/MS for quantitative analysis of small molecules. Biomed. Chromatogr. 24(1), 49-65 (2010).